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The map label for this gene is etfA [H]

Identifier: 148360429

GI number: 148360429

Start: 1103237

End: 1104175

Strand: Direct

Name: etfA [H]

Synonym: LPC_2368

Alternate gene names: 148360429

Gene position: 1103237-1104175 (Clockwise)

Preceding gene: 148360430

Following gene: 148360428

Centisome position: 30.85

GC content: 39.4

Gene sequence:

>939_bases
ATGAGCACTTTAGTTTTAGTTGAACATAATAATCAGCAGTTACATCCAGCAACCCGTAATACACTGTCTGCTGCTTTAGA
ACTCGGTGATAAAATTACGTTACTAGTAGTTGGATATCAATGCCGTTCAGTAGCCGAGGAGGCAGCCATTCTCAAAGGAG
TTCATGCTGTTTTGCATGTAGATAATCCTTGTTACGAACATCAATTGACTGAAGCAGTTAGCGATTTGGTGGTGTCTTTT
GCGAATTCATTCAGTGCTATTTTAGCTCCTTCCAGTACTTATGGGAAAAATATATTGCCCAGAGTTGCCGCACAACTTGA
TGTGACCCAGATTTCTGATGTGAGCAAGATAATTAATTCAGACACATTTGAACATCCTGTTTATGCTGGTAATGCCATAG
AGACTGTGCGTGTTTTGGATTCATTAAAAGTAATGACTATTAGAACGACAGTTTTTGATTCCATCACATCAAGTCAGGAA
GCATGTTGCATAGAAAGTATTGATAAGGAATTTCAAGCCAAAGGAAGTCAATTTGTGCGCCATGAATTAAGTAAATCCGA
GAGACCGGATTTAGGTAGCGCTAAAATAGTTGTTTCTGGCGGTAGGGGACTACAAAGTGCAGAAAAATTTAAATTAATCG
AAGAGTTAGCTGATACTTTGGGCGCAGCAGTAGGGGCATCCAGAGCTGCAGTAGATGCCGGTTTTGTTCCTAATGATTAT
CAGGTTGGTCAAACCGGGAAGGTAGTAGCTCCTATGCTTTATATTGCCGTGGGTATTTCTGGAGCAGTTCAACATTTGGC
AGGTATGAAGGATTCCAAGGTTATTGTTGCAATTAATAAAGACGCAGATGCACCTATTTTTCAAATCGCGACTTATGGGT
TAGTAGGTGATCTGTTTGAATTAGTTCCACAATTAATAGAACAATTAAAGAATCGATAA

Upstream 100 bases:

>100_bases
GCCCCGGCAACGAGAAGTGGTGGTGTCATACTTGATTCTGTGGCTGCATTGTTGGATAAATTACAACATGAAGCCAAAGT
GCTTTAATTAAGGAGATGAG

Downstream 100 bases:

>100_bases
GAGGTAACAATATGTTAGTAGGGGTACCAAAAGAAATCAAATCGCACGAAAACAGAGTAGGACTTGTTCCCTCGAGTGTT
AGAGAAATTATTAGGGCAGG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSTLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAAILKGVHAVLHVDNPCYEHQLTEAVSDLVVSF
ANSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINSDTFEHPVYAGNAIETVRVLDSLKVMTIRTTVFDSITSSQE
ACCIESIDKEFQAKGSQFVRHELSKSERPDLGSAKIVVSGGRGLQSAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDY
QVGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFELVPQLIEQLKNR

Sequences:

>Translated_312_residues
MSTLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAAILKGVHAVLHVDNPCYEHQLTEAVSDLVVSF
ANSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINSDTFEHPVYAGNAIETVRVLDSLKVMTIRTTVFDSITSSQE
ACCIESIDKEFQAKGSQFVRHELSKSERPDLGSAKIVVSGGRGLQSAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDY
QVGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFELVPQLIEQLKNR
>Mature_311_residues
STLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAAILKGVHAVLHVDNPCYEHQLTEAVSDLVVSFA
NSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINSDTFEHPVYAGNAIETVRVLDSLKVMTIRTTVFDSITSSQEA
CCIESIDKEFQAKGSQFVRHELSKSERPDLGSAKIVVSGGRGLQSAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDYQ
VGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFELVPQLIEQLKNR

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=313, Percent_Identity=52.3961661341853, Blast_Score=319, Evalue=2e-87,
Organism=Homo sapiens, GI189181759, Length=273, Percent_Identity=53.1135531135531, Blast_Score=281, Evalue=4e-76,
Organism=Escherichia coli, GI1787990, Length=235, Percent_Identity=35.3191489361702, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1786226, Length=229, Percent_Identity=35.3711790393013, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87082157, Length=118, Percent_Identity=39.8305084745763, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=310, Percent_Identity=51.9354838709677, Blast_Score=319, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6325261, Length=296, Percent_Identity=44.5945945945946, Blast_Score=226, Evalue=4e-60,
Organism=Drosophila melanogaster, GI17136898, Length=311, Percent_Identity=53.3762057877814, Blast_Score=327, Evalue=5e-90,
Organism=Drosophila melanogaster, GI24652801, Length=311, Percent_Identity=53.3762057877814, Blast_Score=327, Evalue=5e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33418; Mature: 33286

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAAILKGVHAVLHV
CCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHEEEC
DNPCYEHQLTEAVSDLVVSFANSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCC
DTFEHPVYAGNAIETVRVLDSLKVMTIRTTVFDSITSSQEACCIESIDKEFQAKGSQFVR
CCCCCCCCCCCHHHHHHHHHHHHHEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
HELSKSERPDLGSAKIVVSGGRGLQSAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDY
HHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
LVPQLIEQLKNR
HHHHHHHHHHCC
>Mature Secondary Structure 
STLVLVEHNNQQLHPATRNTLSAALELGDKITLLVVGYQCRSVAEEAAILKGVHAVLHV
CEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHEEEC
DNPCYEHQLTEAVSDLVVSFANSFSAILAPSSTYGKNILPRVAAQLDVTQISDVSKIINS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCC
DTFEHPVYAGNAIETVRVLDSLKVMTIRTTVFDSITSSQEACCIESIDKEFQAKGSQFVR
CCCCCCCCCCCHHHHHHHHHHHHHEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
HELSKSERPDLGSAKIVVSGGRGLQSAEKFKLIEELADTLGAAVGASRAAVDAGFVPNDY
HHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPMLYIAVGISGAVQHLAGMKDSKVIVAINKDADAPIFQIATYGLVGDLFE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
LVPQLIEQLKNR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]