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The map label for this gene is yciR [C]

Identifier: 148360207

GI number: 148360207

Start: 1342711

End: 1345095

Strand: Reverse

Name: yciR [C]

Synonym: LPC_2139

Alternate gene names: 148360207

Gene position: 1345095-1342711 (Counterclockwise)

Preceding gene: 148360206

Following gene: 148360208

Centisome position: 37.61

GC content: 36.06

Gene sequence:

>2385_bases
GTGATTTCAAACTACCCTGTAATCACTCAAAACTTCTGGTATCAACTGGTTGAAAAAATGGCTATAGGGGTGTTGGTGAT
TAATAATGAAGGGCGAATTCTTTATGCGAATGATTATGTAGTGCAAATCTTTGGTGTACCCAGCACAGAACTTGTTGGCA
CCAATTTTTTATATCCTATGGCTGCAAATGAAACACAGGAAGTTGAAATTTTAAAATCCAATAATGAAGTTTTAACAGCT
CATATGACAGTCAAGAAAAGTATCTGGGAAAATCGCCAGGTATGGATTATTTCTCTCTTTGATATTACAGAGCTCAAATT
AAAAGAAAAACTTTTGAAAATTTCAAGCAAAGGCATCAGTTCAGCCTTTGAAGGCATTATCATCATCGATCCCGAAGGCA
CGATTATTGAAGCCAATAACGCGTTTATGAAAATGACCGGATATACAGAAAAAGAAATCATAGGACAAAAACCTGTTCTC
TTGCATTCAAGGAAGCAAAACGAGAAATTTTACAAGGAGCTATGGAATATACTCATGGCGAAGGGTCGGTGGAGCGGTGA
ACTTTGGGCAAAAAAGAAAAATAAAAGGTTATTTCCTGCCTTTTTAGCCATTTCGGCTGTTAAAAACTCCGATGGTGACG
TGATTAATTACATTGGTTATTATCACGATTTAACGTTAATAAAAAAACAAGAACAACAAATCGAGAGTTTCAAATATTAT
GACTATTTAACAGGACTACCGAACAAACTTTTACTCACCCAAAGACTTCAGATGCTCATTAACAGATTATCCGAGGAAAA
TAAAGAACTCATCATTTTTAATATCAGGATATTTGATTCGAGTAGCAAAAACTCTCTGTTAGATTTTCTTCCAAATATCC
GAGATAAAATCATCTTGGAGGTGGTTAAGCGTATTGACCGAACATCACCTAAAAAAATGTTTTTCTCACGCATCGGCTTG
AGTGAGTTTATTGTTGTTTATTTTATCAAATGTAGAATTGAAGTAATGGCTTCCATCGCCCAGAGAATGATAGAAAAACT
CTCTTGCCCTTATCACATTGGTCACAAAACTATTATCTTGCAAACGATCATTGGATTAACTGCGTACTACAAAAATACCG
CGTTCAGTGCCGAGGATTTTTTGCAACAATCAGAAGTTGCCCGCCACAAAGCCCAAATCAAGGGTATTAATATTTTTGAG
TTTTTTGACCCTCAGGTTGAAGAGCGAATTATAGAATTTAATAAACGCATAGAATCTGTCTCTAAAGCAATCCAGTTAAA
TGAGTTGAAAATTTACTACCAACCTATTGTGGAATTAAGTAAAGCTGAAGTGGCAAGTTTGGAGGCTTTGCTGCGCTGGA
AACACCCCAAAAAAGGCCTGTTACTTCCAAAACAATTTTTATCTGACATCGATAATCACCCTCTTTCTCTGCAACTTGGA
GATTGGGTTCTGCATCAGGTATTAGAGCAAATTGAAAAACTACTGGCATGCGGCATAAAAATTCCCATTCACATTAATGT
GAGCGCTTATCAGCTGCAACATCCCAATTTTGTCAAAAAACTGTTTGACACATTGGCACTATACCCAAGCGTTCCCCCTC
ACCTAATCATGCTTGAAGTCCTTGAAACAGAAGCCATTGAAGATTTGATATTAGTATCTCAGATAATAGCCGAATGTAAG
ACCAAGGGAGTCAACTTTTCTTTGGATGATTTTGGAACAGGTTATGCCTCTTTAACTTTTCTTAAAGAATTGAATACAAC
TGAAGTTAAAATTGATCGAAGTTTTATCATTGATATTTTTGATAACCCGAAGGAACTTGTTCTTCTGAAAACAATGATAG
AATTTTGCCGAGTCATTGGTCGTACCCTGGTTGCAGAAGGGGTTGAAACAGTAGCACATGGGAAATTATTAAGCTTGTTT
GGTTGCAATCTAATCCAAGGCTACGCTATTGCCAAACCTATCCCCGCTACCAAATTAATTCCATGGATAAAAAACTGGAA
GCTTGCTCCAGAATGGGGAGAAAACCGGTTTTCGCATGCCGCATTAAATAAATTAGTCAAAATCTCCATAAAACACTATC
TTAACTTTCAATTAATCAGACTTTATTTAGAGAATGATCAATCTCTCAAACCTGAATTATCACTTCAAGCATGCCCAATA
GAGCAGTGGTTTCTTGAAAACCAACAAACAATCAAAGAGGACAGGCGATTTAAAAAAGTCTGTGATTTACATCACAAGGA
ACATCAATTGGGCAATATAATAATTCAGTTAATTCAAACAGGGCAAAAAGAACAAGCGGCCAAACAACTGGTAAGCCTTG
ATAGTTTAAGAATTAATTTCTTGAAAGAGTTAATGCATTTCATTTGTAATTCAAATACCATTTAA

Upstream 100 bases:

>100_bases
TACTAATTAAAAAAGAACCCTTGCCTGAACGTCGAATCATCGGTGATTTATCTGATAGACAAAAAGTTATTGCTGCTCTG
GAAATGGATTAGGTGATATC

Downstream 100 bases:

>100_bases
TTGATTACATAATGCACTTCAATTAAAACGCCTGATTACATCCAAGAGAAGCCTCAAGATTTTCTTAATTTCAACTTTAG
CCACTTTTTCGTAAACTGCT

Product: GGDEF/EAL domain-containing sensory box protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 794

Protein sequence:

>794_residues
MISNYPVITQNFWYQLVEKMAIGVLVINNEGRILYANDYVVQIFGVPSTELVGTNFLYPMAANETQEVEILKSNNEVLTA
HMTVKKSIWENRQVWIISLFDITELKLKEKLLKISSKGISSAFEGIIIIDPEGTIIEANNAFMKMTGYTEKEIIGQKPVL
LHSRKQNEKFYKELWNILMAKGRWSGELWAKKKNKRLFPAFLAISAVKNSDGDVINYIGYYHDLTLIKKQEQQIESFKYY
DYLTGLPNKLLLTQRLQMLINRLSEENKELIIFNIRIFDSSSKNSLLDFLPNIRDKIILEVVKRIDRTSPKKMFFSRIGL
SEFIVVYFIKCRIEVMASIAQRMIEKLSCPYHIGHKTIILQTIIGLTAYYKNTAFSAEDFLQQSEVARHKAQIKGINIFE
FFDPQVEERIIEFNKRIESVSKAIQLNELKIYYQPIVELSKAEVASLEALLRWKHPKKGLLLPKQFLSDIDNHPLSLQLG
DWVLHQVLEQIEKLLACGIKIPIHINVSAYQLQHPNFVKKLFDTLALYPSVPPHLIMLEVLETEAIEDLILVSQIIAECK
TKGVNFSLDDFGTGYASLTFLKELNTTEVKIDRSFIIDIFDNPKELVLLKTMIEFCRVIGRTLVAEGVETVAHGKLLSLF
GCNLIQGYAIAKPIPATKLIPWIKNWKLAPEWGENRFSHAALNKLVKISIKHYLNFQLIRLYLENDQSLKPELSLQACPI
EQWFLENQQTIKEDRRFKKVCDLHHKEHQLGNIIIQLIQTGQKEQAAKQLVSLDSLRINFLKELMHFICNSNTI

Sequences:

>Translated_794_residues
MISNYPVITQNFWYQLVEKMAIGVLVINNEGRILYANDYVVQIFGVPSTELVGTNFLYPMAANETQEVEILKSNNEVLTA
HMTVKKSIWENRQVWIISLFDITELKLKEKLLKISSKGISSAFEGIIIIDPEGTIIEANNAFMKMTGYTEKEIIGQKPVL
LHSRKQNEKFYKELWNILMAKGRWSGELWAKKKNKRLFPAFLAISAVKNSDGDVINYIGYYHDLTLIKKQEQQIESFKYY
DYLTGLPNKLLLTQRLQMLINRLSEENKELIIFNIRIFDSSSKNSLLDFLPNIRDKIILEVVKRIDRTSPKKMFFSRIGL
SEFIVVYFIKCRIEVMASIAQRMIEKLSCPYHIGHKTIILQTIIGLTAYYKNTAFSAEDFLQQSEVARHKAQIKGINIFE
FFDPQVEERIIEFNKRIESVSKAIQLNELKIYYQPIVELSKAEVASLEALLRWKHPKKGLLLPKQFLSDIDNHPLSLQLG
DWVLHQVLEQIEKLLACGIKIPIHINVSAYQLQHPNFVKKLFDTLALYPSVPPHLIMLEVLETEAIEDLILVSQIIAECK
TKGVNFSLDDFGTGYASLTFLKELNTTEVKIDRSFIIDIFDNPKELVLLKTMIEFCRVIGRTLVAEGVETVAHGKLLSLF
GCNLIQGYAIAKPIPATKLIPWIKNWKLAPEWGENRFSHAALNKLVKISIKHYLNFQLIRLYLENDQSLKPELSLQACPI
EQWFLENQQTIKEDRRFKKVCDLHHKEHQLGNIIIQLIQTGQKEQAAKQLVSLDSLRINFLKELMHFICNSNTI
>Mature_794_residues
MISNYPVITQNFWYQLVEKMAIGVLVINNEGRILYANDYVVQIFGVPSTELVGTNFLYPMAANETQEVEILKSNNEVLTA
HMTVKKSIWENRQVWIISLFDITELKLKEKLLKISSKGISSAFEGIIIIDPEGTIIEANNAFMKMTGYTEKEIIGQKPVL
LHSRKQNEKFYKELWNILMAKGRWSGELWAKKKNKRLFPAFLAISAVKNSDGDVINYIGYYHDLTLIKKQEQQIESFKYY
DYLTGLPNKLLLTQRLQMLINRLSEENKELIIFNIRIFDSSSKNSLLDFLPNIRDKIILEVVKRIDRTSPKKMFFSRIGL
SEFIVVYFIKCRIEVMASIAQRMIEKLSCPYHIGHKTIILQTIIGLTAYYKNTAFSAEDFLQQSEVARHKAQIKGINIFE
FFDPQVEERIIEFNKRIESVSKAIQLNELKIYYQPIVELSKAEVASLEALLRWKHPKKGLLLPKQFLSDIDNHPLSLQLG
DWVLHQVLEQIEKLLACGIKIPIHINVSAYQLQHPNFVKKLFDTLALYPSVPPHLIMLEVLETEAIEDLILVSQIIAECK
TKGVNFSLDDFGTGYASLTFLKELNTTEVKIDRSFIIDIFDNPKELVLLKTMIEFCRVIGRTLVAEGVETVAHGKLLSLF
GCNLIQGYAIAKPIPATKLIPWIKNWKLAPEWGENRFSHAALNKLVKISIKHYLNFQLIRLYLENDQSLKPELSLQACPI
EQWFLENQQTIKEDRRFKKVCDLHHKEHQLGNIIIQLIQTGQKEQAAKQLVSLDSLRINFLKELMHFICNSNTI

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=570, Percent_Identity=26.8421052631579, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI87081921, Length=456, Percent_Identity=26.7543859649123, Blast_Score=165, Evalue=8e-42,
Organism=Escherichia coli, GI226510982, Length=429, Percent_Identity=27.2727272727273, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788502, Length=259, Percent_Identity=31.2741312741313, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787055, Length=258, Percent_Identity=28.6821705426357, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI87081845, Length=258, Percent_Identity=31.0077519379845, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI87081980, Length=256, Percent_Identity=27.734375, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081743, Length=257, Percent_Identity=29.5719844357977, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1786507, Length=250, Percent_Identity=28.8, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87082096, Length=243, Percent_Identity=29.6296296296296, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788849, Length=242, Percent_Identity=28.9256198347107, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788381, Length=579, Percent_Identity=21.4162348877375, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 91662; Mature: 91662

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNYPVITQNFWYQLVEKMAIGVLVINNEGRILYANDYVVQIFGVPSTELVGTNFLYPM
CCCCCCEEHHHHHHHHHHHHHCEEEEECCCCCEEEECCEEEEEECCCCCHHCCCCEEEEE
AANETQEVEILKSNNEVLTAHMTVKKSIWENRQVWIISLFDITELKLKEKLLKISSKGIS
CCCCCCEEEEEECCCCEEEEEHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHCCCCH
SAFEGIIIIDPEGTIIEANNAFMKMTGYTEKEIIGQKPVLLHSRKQNEKFYKELWNILMA
HHHCCEEEECCCCCEEECCCCEEEECCCCHHHHCCCCCCEECCCCCCHHHHHHHHHHHHH
KGRWSGELWAKKKNKRLFPAFLAISAVKNSDGDVINYIGYYHDLTLIKKQEQQIESFKYY
CCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
DYLTGLPNKLLLTQRLQMLINRLSEENKELIIFNIRIFDSSSKNSLLDFLPNIRDKIILE
HHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHCCHHHHHHHH
VVKRIDRTSPKKMFFSRIGLSEFIVVYFIKCRIEVMASIAQRMIEKLSCPYHIGHKTIIL
HHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHH
QTIIGLTAYYKNTAFSAEDFLQQSEVARHKAQIKGINIFEFFDPQVEERIIEFNKRIESV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHH
SKAIQLNELKIYYQPIVELSKAEVASLEALLRWKHPKKGLLLPKQFLSDIDNHPLSLQLG
HHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEHH
DWVLHQVLEQIEKLLACGIKIPIHINVSAYQLQHPNFVKKLFDTLALYPSVPPHLIMLEV
HHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHH
LETEAIEDLILVSQIIAECKTKGVNFSLDDFGTGYASLTFLKELNTTEVKIDRSFIIDIF
HHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCCHHHHHHHHHCCCCEEEEEEEEEEEEC
DNPKELVLLKTMIEFCRVIGRTLVAEGVETVAHGKLLSLFGCNLIQGYAIAKPIPATKLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHCCCHHCCCCCCHHHH
PWIKNWKLAPEWGENRFSHAALNKLVKISIKHYLNFQLIRLYLENDQSLKPELSLQACPI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCCEEECCC
EQWFLENQQTIKEDRRFKKVCDLHHKEHQLGNIIIQLIQTGQKEQAAKQLVSLDSLRINF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LKELMHFICNSNTI
HHHHHHHHHCCCCC
>Mature Secondary Structure
MISNYPVITQNFWYQLVEKMAIGVLVINNEGRILYANDYVVQIFGVPSTELVGTNFLYPM
CCCCCCEEHHHHHHHHHHHHHCEEEEECCCCCEEEECCEEEEEECCCCCHHCCCCEEEEE
AANETQEVEILKSNNEVLTAHMTVKKSIWENRQVWIISLFDITELKLKEKLLKISSKGIS
CCCCCCEEEEEECCCCEEEEEHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHCCCCH
SAFEGIIIIDPEGTIIEANNAFMKMTGYTEKEIIGQKPVLLHSRKQNEKFYKELWNILMA
HHHCCEEEECCCCCEEECCCCEEEECCCCHHHHCCCCCCEECCCCCCHHHHHHHHHHHHH
KGRWSGELWAKKKNKRLFPAFLAISAVKNSDGDVINYIGYYHDLTLIKKQEQQIESFKYY
CCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
DYLTGLPNKLLLTQRLQMLINRLSEENKELIIFNIRIFDSSSKNSLLDFLPNIRDKIILE
HHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHCCHHHHHHHH
VVKRIDRTSPKKMFFSRIGLSEFIVVYFIKCRIEVMASIAQRMIEKLSCPYHIGHKTIIL
HHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHH
QTIIGLTAYYKNTAFSAEDFLQQSEVARHKAQIKGINIFEFFDPQVEERIIEFNKRIESV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHH
SKAIQLNELKIYYQPIVELSKAEVASLEALLRWKHPKKGLLLPKQFLSDIDNHPLSLQLG
HHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCEEEEHH
DWVLHQVLEQIEKLLACGIKIPIHINVSAYQLQHPNFVKKLFDTLALYPSVPPHLIMLEV
HHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHH
LETEAIEDLILVSQIIAECKTKGVNFSLDDFGTGYASLTFLKELNTTEVKIDRSFIIDIF
HHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCCHHHHHHHHHCCCCEEEEEEEEEEEEC
DNPKELVLLKTMIEFCRVIGRTLVAEGVETVAHGKLLSLFGCNLIQGYAIAKPIPATKLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHCCCHHCCCCCCHHHH
PWIKNWKLAPEWGENRFSHAALNKLVKISIKHYLNFQLIRLYLENDQSLKPELSLQACPI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCCEEECCC
EQWFLENQQTIKEDRRFKKVCDLHHKEHQLGNIIIQLIQTGQKEQAAKQLVSLDSLRINF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LKELMHFICNSNTI
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]