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The map label for this gene is bioC [C]

Identifier: 148360062

GI number: 148360062

Start: 2974884

End: 2976617

Strand: Direct

Name: bioC [C]

Synonym: LPC_1993

Alternate gene names: 148360062

Gene position: 2974884-2976617 (Clockwise)

Preceding gene: 148360063

Following gene: 148360058

Centisome position: 83.18

GC content: 38.41

Gene sequence:

>1734_bases
ATGAACAGTGAAGTAGATACTCTTTTTGCACAAGCCTATAAGCTTCAATATGAAGGCCATTTACCTCAAGCCATTAGCTT
ATATGAGCAAATACTTGCCCAATCACCCAAACATACGGAAACTCTGCATTTCCTGGGATTAACCTATGCCCAATTGGGTG
ATATGGAAAATGCCATTTTATATTTTTTGCAAGCCAGAAAAATTAACCCCAATGACGTTGGTATACTCAATAATCTCGCT
AACGCTTATAAAAAGGCAGGTCAATTAGATGAGGCAATTAAATACTACCAGCAAGCCATTGAGATTAAACCAGAGTATGT
CCAGGCTCATAATAATCTGGCAGCAACCTACGCATTACTCAACAATTACCAGAAAGCGTTGCATCATTATGTGATTGCAG
TGAATACAGAACCTGACTTTAGCGCGGCTCACTTTAATTTAGGTTTGTTACTTCTCAAAAATCAACAATTGTCTGCTGCC
AAAACACAATTTAATAATGTGATAGCTCTAAATCCCCAGCACAGAGAAGCTCAATTTTACTTAGGTATTTTGCATTTGGA
AGACAATTTACTCTCAGAAGCAGAACAGGCATTTCATAAAGTGTTAGAGCAAGATCATGAACATGTTCAATCCCTAATTA
ACTTGGGCGTGATCGCTTTGAAAAGAGAACAAAACCAATTGGCTGTTGATTATTTTACCAAAGCCTTGGCTTTGGATAAT
GAAGACATTGATGCACGTAATAATTTGGCAGCCACCTTCATGCATCATGATCGATTTGAAAATGCGCTCATGCATTACGA
TGTTTTACTGAAAAAAGAACCCGATAATCTGGAGTATTTATACAATTCCGGAGTCGCTCAAATGGCATTGGGCCATCTCA
ATGAAGCCACCCTTTTGTTTGATCAGATTTTAACATTACAAAGTGATCACACCCCATCCTTGAATAATCTGGCCGCTATT
TATTTAAAAATGGACATGCGAGAAACCGCGCGCGAATATCTTGAGCGCGCACTGGTAATCAACCCCGATGATGTGGTCAG
CAGGCATATGCTGAATGCCATTACAGGAGCAACGAGCGTTAATACTACAGAAAAATATGCCCAAAATTTATTTAATAATT
ATGCCTTGTATTACGATCAACACATGCAAGGTGAATTACACTATAAGATTCCGCATCACATTGGCCGCCTCATCCACCAA
CTTCAACTTTTGCAAACCAGTCATTCTTTGGACTTGGGTTGTGGTACTGGATTAACAGGTATTGTGCTTCGTGAAATAAG
CAAACACTTAACCGGAGTAGATATAGCAGAAAAAATGATAGCTCGAGCAAAGGAAAAAAACATCTATGATCTTCTGGTAT
GCTCGGAATTAATCGATTTTTTAAGAAAAGATAAAAACGATTACGATTTAGCGGTCGCTGCAGACGTCCTACCCTATTTT
GGTAATCTCGATGATATTTTTAATTCCATCAATCAACATCTGAAGCAAGAAGGGTATTTTATTTTCACTACCGAAATCAG
CACAACAACTCCGTGGAAACTGGAAAGCAGCGCTCGATTTAGCCATCAACCCGAATACATAGAGAGCTTAATCAATAAAT
ACCAATTTCATCTTATCAAACAAGAGAAAATACCAGGCCGAACACAAAACAAACAAGTGCTGGAAGTCATGTTGTATTGT
GTTAAGAAGTCAACATCTCATTTTGTTTCCAACAGAACTTACGAAACCCCCTAA

Upstream 100 bases:

>100_bases
TATCAATGCACAGCCGCTGAATTACCTGCTAAAATTAAAAATAGGATTAGCCATCGCGCAAAAGCTTTAAACCAATTACG
CGCCCTTCTTCCAGATTAAT

Downstream 100 bases:

>100_bases
TCTCTATATTAAAAAATGAACCTTGGGCTTTTTCGTTAGTCCTGTCCAAATCTGACAAATTCTGAGCAGAATAGCACTAT
ATTGAATTTTTCATATTCCT

Product: methyltransferase

Products: NA

Alternate protein names: Methyltransferase Type; TPR Domain-Containing Protein; Tetratricopeptide TPR_2 Repeat Protein; Methyltransferase; Tetratricopeptide Repeat Domain Protein; Tetratricopeptide Repeat Family; Peptidase; 3-Demethylubiquinone-9 3-Methyltransferase; Methyltransferase Protein; Tetratricopeptide TPR_1 Repeat-Containing Protein; Tetratricopeptide Repeat-Containing Protein; PEP-CTERM System TPR-Repeat Lipoprotein; O-Linked GlcNAc Transferase; O-Linked N-Acetylglucosamine Transferase; SPY Protein; TPR Repeat Protein; TPR Repeat-Containing Methyltransferase; O-GlcNAc Transferase; SAM-Dependent Methyltransferase; TPR Repeat-Containing Serine/Threonin Protein Kinase; TPR Domain-Containing Protein Putative Methyltransferase; Sulfotransferase; Two Domain Fusion Protein; TPR Domain Protein; Methyltransferase Domain Family; Peptidase S1 And S6 Chymotrypsin/Hap; FkbM Family Methyltransferase; Glycosyl Transferase Family Protein; Methyltransferase Domain Family Protein; SAM-Dependent Methyltransferases; Tetratricopeptide Repeat Domain-Containing Protein; LOW QUALITY PROTEIN Methyltransferase; Protein With TPR Motifs; Tetratricopeptide Domain-Containing Protein

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNSEVDTLFAQAYKLQYEGHLPQAISLYEQILAQSPKHTETLHFLGLTYAQLGDMENAILYFLQARKINPNDVGILNNLA
NAYKKAGQLDEAIKYYQQAIEIKPEYVQAHNNLAATYALLNNYQKALHHYVIAVNTEPDFSAAHFNLGLLLLKNQQLSAA
KTQFNNVIALNPQHREAQFYLGILHLEDNLLSEAEQAFHKVLEQDHEHVQSLINLGVIALKREQNQLAVDYFTKALALDN
EDIDARNNLAATFMHHDRFENALMHYDVLLKKEPDNLEYLYNSGVAQMALGHLNEATLLFDQILTLQSDHTPSLNNLAAI
YLKMDMRETAREYLERALVINPDDVVSRHMLNAITGATSVNTTEKYAQNLFNNYALYYDQHMQGELHYKIPHHIGRLIHQ
LQLLQTSHSLDLGCGTGLTGIVLREISKHLTGVDIAEKMIARAKEKNIYDLLVCSELIDFLRKDKNDYDLAVAADVLPYF
GNLDDIFNSINQHLKQEGYFIFTTEISTTTPWKLESSARFSHQPEYIESLINKYQFHLIKQEKIPGRTQNKQVLEVMLYC
VKKSTSHFVSNRTYETP

Sequences:

>Translated_577_residues
MNSEVDTLFAQAYKLQYEGHLPQAISLYEQILAQSPKHTETLHFLGLTYAQLGDMENAILYFLQARKINPNDVGILNNLA
NAYKKAGQLDEAIKYYQQAIEIKPEYVQAHNNLAATYALLNNYQKALHHYVIAVNTEPDFSAAHFNLGLLLLKNQQLSAA
KTQFNNVIALNPQHREAQFYLGILHLEDNLLSEAEQAFHKVLEQDHEHVQSLINLGVIALKREQNQLAVDYFTKALALDN
EDIDARNNLAATFMHHDRFENALMHYDVLLKKEPDNLEYLYNSGVAQMALGHLNEATLLFDQILTLQSDHTPSLNNLAAI
YLKMDMRETAREYLERALVINPDDVVSRHMLNAITGATSVNTTEKYAQNLFNNYALYYDQHMQGELHYKIPHHIGRLIHQ
LQLLQTSHSLDLGCGTGLTGIVLREISKHLTGVDIAEKMIARAKEKNIYDLLVCSELIDFLRKDKNDYDLAVAADVLPYF
GNLDDIFNSINQHLKQEGYFIFTTEISTTTPWKLESSARFSHQPEYIESLINKYQFHLIKQEKIPGRTQNKQVLEVMLYC
VKKSTSHFVSNRTYETP
>Mature_577_residues
MNSEVDTLFAQAYKLQYEGHLPQAISLYEQILAQSPKHTETLHFLGLTYAQLGDMENAILYFLQARKINPNDVGILNNLA
NAYKKAGQLDEAIKYYQQAIEIKPEYVQAHNNLAATYALLNNYQKALHHYVIAVNTEPDFSAAHFNLGLLLLKNQQLSAA
KTQFNNVIALNPQHREAQFYLGILHLEDNLLSEAEQAFHKVLEQDHEHVQSLINLGVIALKREQNQLAVDYFTKALALDN
EDIDARNNLAATFMHHDRFENALMHYDVLLKKEPDNLEYLYNSGVAQMALGHLNEATLLFDQILTLQSDHTPSLNNLAAI
YLKMDMRETAREYLERALVINPDDVVSRHMLNAITGATSVNTTEKYAQNLFNNYALYYDQHMQGELHYKIPHHIGRLIHQ
LQLLQTSHSLDLGCGTGLTGIVLREISKHLTGVDIAEKMIARAKEKNIYDLLVCSELIDFLRKDKNDYDLAVAADVLPYF
GNLDDIFNSINQHLKQEGYFIFTTEISTTTPWKLESSARFSHQPEYIESLINKYQFHLIKQEKIPGRTQNKQVLEVMLYC
VKKSTSHFVSNRTYETP

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG4976

COG function: function code R; Predicted methyltransferase (contains TPR repeat)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32307150, Length=379, Percent_Identity=25.3298153034301, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI32307148, Length=379, Percent_Identity=25.3298153034301, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI224809432, Length=319, Percent_Identity=25.3918495297806, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI301336134, Length=331, Percent_Identity=23.8670694864048, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI83415184, Length=331, Percent_Identity=23.8670694864048, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI118766330, Length=251, Percent_Identity=25.8964143426295, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI118766328, Length=251, Percent_Identity=25.8964143426295, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115532692, Length=363, Percent_Identity=25.068870523416, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115532690, Length=363, Percent_Identity=25.068870523416, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25147174, Length=270, Percent_Identity=23.7037037037037, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319387, Length=151, Percent_Identity=30.4635761589404, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17647755, Length=314, Percent_Identity=27.0700636942675, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585827, Length=314, Percent_Identity=27.0700636942675, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585829, Length=314, Percent_Identity=27.0700636942675, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24656717, Length=293, Percent_Identity=27.9863481228669, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI18110006, Length=293, Percent_Identity=27.9863481228669, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647123, Length=267, Percent_Identity=22.8464419475655, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 66035; Mature: 66035

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSEVDTLFAQAYKLQYEGHLPQAISLYEQILAQSPKHTETLHFLGLTYAQLGDMENAIL
CCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHH
YFLQARKINPNDVGILNNLANAYKKAGQLDEAIKYYQQAIEIKPEYVQAHNNLAATYALL
HHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHH
NNYQKALHHYVIAVNTEPDFSAAHFNLGLLLLKNQQLSAAKTQFNNVIALNPQHREAQFY
HHHHHHHHEEEEEEECCCCCCCHHCCEEEEEEECCCHHHHHHHHCCEEEECCCCCCCEEE
LGILHLEDNLLSEAEQAFHKVLEQDHEHVQSLINLGVIALKREQNQLAVDYFTKALALDN
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCC
EDIDARNNLAATFMHHDRFENALMHYDVLLKKEPDNLEYLYNSGVAQMALGHLNEATLLF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCHHHHHHHCCCHHHHHH
DQILTLQSDHTPSLNNLAAIYLKMDMRETAREYLERALVINPDDVVSRHMLNAITGATSV
HHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHHHHHCEEECCHHHHHHHHHHHHHCCCCC
NTTEKYAQNLFNNYALYYDQHMQGELHYKIPHHIGRLIHQLQLLQTSHSLDLGCGTGLTG
CCHHHHHHHHHHCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
IVLREISKHLTGVDIAEKMIARAKEKNIYDLLVCSELIDFLRKDKNDYDLAVAADVLPYF
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
GNLDDIFNSINQHLKQEGYFIFTTEISTTTPWKLESSARFSHQPEYIESLINKYQFHLIK
CCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHEE
QEKIPGRTQNKQVLEVMLYCVKKSTSHFVSNRTYETP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNSEVDTLFAQAYKLQYEGHLPQAISLYEQILAQSPKHTETLHFLGLTYAQLGDMENAIL
CCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHH
YFLQARKINPNDVGILNNLANAYKKAGQLDEAIKYYQQAIEIKPEYVQAHNNLAATYALL
HHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHH
NNYQKALHHYVIAVNTEPDFSAAHFNLGLLLLKNQQLSAAKTQFNNVIALNPQHREAQFY
HHHHHHHHEEEEEEECCCCCCCHHCCEEEEEEECCCHHHHHHHHCCEEEECCCCCCCEEE
LGILHLEDNLLSEAEQAFHKVLEQDHEHVQSLINLGVIALKREQNQLAVDYFTKALALDN
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCC
EDIDARNNLAATFMHHDRFENALMHYDVLLKKEPDNLEYLYNSGVAQMALGHLNEATLLF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCCHHHHHHHCCCHHHHHH
DQILTLQSDHTPSLNNLAAIYLKMDMRETAREYLERALVINPDDVVSRHMLNAITGATSV
HHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHHHHHCEEECCHHHHHHHHHHHHHCCCCC
NTTEKYAQNLFNNYALYYDQHMQGELHYKIPHHIGRLIHQLQLLQTSHSLDLGCGTGLTG
CCHHHHHHHHHHCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
IVLREISKHLTGVDIAEKMIARAKEKNIYDLLVCSELIDFLRKDKNDYDLAVAADVLPYF
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
GNLDDIFNSINQHLKQEGYFIFTTEISTTTPWKLESSARFSHQPEYIESLINKYQFHLIK
CCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHEE
QEKIPGRTQNKQVLEVMLYCVKKSTSHFVSNRTYETP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA