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The map label for this gene is fadH [H]

Identifier: 148359888

GI number: 148359888

Start: 2765041

End: 2767065

Strand: Reverse

Name: fadH [H]

Synonym: LPC_1816

Alternate gene names: 148359888

Gene position: 2767065-2765041 (Counterclockwise)

Preceding gene: 148359890

Following gene: 148359887

Centisome position: 77.37

GC content: 41.58

Gene sequence:

>2025_bases
ATGGAATTGAGAATTGATAATACCCCTTTTAAAGCCATTTTTCAGCCTTTGGATCTGGGCTTTACCCAAATTAAGAATCG
TTTATTGATGGGTTCAATGCACACTGGACTTGAGGAAGATAAAGAAAATTTAAATCGCCTGGCAAGCTTTTATAGAGAAA
GGGCTCAAGGTGGAGTTGGATTAATCGTAACGGGTGGTTTTGCTCCTAACCGAGCTGGCCGTCTGGCTCCCTTCGCTGCC
AAGCTGACTAATAGTAAAGAGCAACATCGGCATGAGGTCATTACTCAAGCGGTCCATGAAGCAGGCGGAAAAATTGCCTT
GCAAATATTGCATGCAGGGCGTTATGGTTATCACCCTTTTATTGTAGCGCCGAGCGGCATTAAATCCCCCATTAGCCCGT
TTAAACCGTGGGAAATGAGTAAAAGACGAATTATCAAAACTATCAAACATTTTGCCCGATGTGCCAGACTGGCTCAATTG
GCTGGCTATGATGGGGTTGAGATCATGGGAAGCGAAGGATATTTGATAAACCAGTTTATAGTCACTCATACCAATCATCG
AAGGGATGAATGGGGAGGAAGTTTCTCTAATCGCATTCGATTTCCTATTGAAATAGTTCGCAGTGTTCGTGAGGCGGTAG
GCGAGCACTTTATTATCATTTATCGCTTGTCTATGCTTGATTTAGTGGCTGAGGGGAGTAATTGGCAGGAAGTGGTTACC
CTCGCTAAAGCCATTGAACAAGCTGGTGCCAGTTTAATCAATACGGGTATAGGTTGGCATGAAGCAAGAATTCCAACGAT
AGGAACGATGGTTCCATCTGCTGCCTTCACTCAAGTGACCCAGCATTTAAAACCGGAAATTAAAATACCTGTAATTACAT
CTAACCGAATTAATACACCAGAATTGGCTAATCAATTATTAGAAGATGGGGTCGCAGATATGATCTCTATGGCCAGACCA
TTTCTAGCGGATCCCTGCTTTGCAGAAAAAGCAAAATTAGGCGAAAGCAAAGCGATTAATGTATGCATCGCTTGTAATCA
AGCATGTCTTGATCAAGTTTTTGTGAACAAAACAGCATCTTGCCTAGTTAATCCCCGCGCATGCAACGAGACAACCTTGG
TTTATGAAACAACAAATCAACCGAAAGCTATTGCTGTAGTTGGTTCTGGGCCAGCTGGCCTTGCTTTTGCTGTAACAGCA
GCTGAGCGAGGGCATAAAATTACCCTGTTTGAAAAAGCGAATCAGATTGGCGGGCAGTTTAATTTAGCGAAAAAAATTCC
TGGAAAAGAAGAGTTTCAGCATACCTTGAATTATTTTGCTTACCAACTCCAAAAGTATAAAGTGGATGTACGTTTGAATA
CCGAAGCTACTGTGGAATTACTTAAAGACTATGATGAAGTGGTCTTGGCCAGTGGAATTATACCCAGAGTTCCCGAAATT
AAAGGTATAGATCATAAAAAGGTGGTGAGTTATATTGATGTGATTACTCAAAACAAACCCGTTGGTTCACGAGTTGCCGT
CATTGGGGCAGGAGGAATTGGTTTTGATGTCGCTGAGTTTTTAACTCATGATCATCAATTGACTTCTGAGCAATTTTATA
ATGAATGGGGAATTGATATTAGCGGGCAGCATAGAGGTGGATTAAAACCACCTGAAATTGCACCGAGCCCTCGTGAAGTG
TATTTATTACAACGCAAAAAAGAAAAAATGGGTAAACGATTGGGAAAAACTACCGGATGGATTCATCGCTCCAGTTTAAA
ACATAAACAAGTCAAAATGTTTTCGGGTGTAAATTACGAGCGTATTGATGATCAGGGATTGCACTTGACTATTGACGACA
AGCCTCAAGTTTTGGAAGTTGATTCTATAGTGATTTGTGCAGGCCAAATAGAATTAAAGAATTTGTATGAGCCTCTGAAA
ATGGCAGGCAAGTTGGTCCATTTAATAGGAGGCGCTTATAAAGCTTTGGAGCTTGACGCACGTCATGCTATTGATCAGGC
TTGTCGGTTGGCTGCATTAGTATGA

Upstream 100 bases:

>100_bases
GAGAGGATTACAAATTAATTGAATCGGTAAAAAATGATTGCTGTATAATAAGCAAGGTTTATACTTTATGTTTTAAGCTT
TAATTAAACAGAGAGTCCTC

Downstream 100 bases:

>100_bases
GTAAAATTGCTGTAGTGATAAATCCTATAGCAGGCGGCGGTCGCGGAAAAAAAATTTGGAAAGTCCTAAAACCCGGGTTA
CATGCCCTATTCGAACAAAC

Product: 2,4-dienoyl-CoA reductase FadH1

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 674; Mature: 674

Protein sequence:

>674_residues
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVGLIVTGGFAPNRAGRLAPFAA
KLTNSKEQHRHEVITQAVHEAGGKIALQILHAGRYGYHPFIVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQL
AGYDGVEIMGSEGYLINQFIVTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTPELANQLLEDGVADMISMARP
FLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTASCLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTA
AERGHKITLFEKANQIGGQFNLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDISGQHRGGLKPPEIAPSPREV
YLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMFSGVNYERIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLK
MAGKLVHLIGGAYKALELDARHAIDQACRLAALV

Sequences:

>Translated_674_residues
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVGLIVTGGFAPNRAGRLAPFAA
KLTNSKEQHRHEVITQAVHEAGGKIALQILHAGRYGYHPFIVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQL
AGYDGVEIMGSEGYLINQFIVTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTPELANQLLEDGVADMISMARP
FLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTASCLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTA
AERGHKITLFEKANQIGGQFNLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDISGQHRGGLKPPEIAPSPREV
YLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMFSGVNYERIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLK
MAGKLVHLIGGAYKALELDARHAIDQACRLAALV
>Mature_674_residues
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVGLIVTGGFAPNRAGRLAPFAA
KLTNSKEQHRHEVITQAVHEAGGKIALQILHAGRYGYHPFIVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQL
AGYDGVEIMGSEGYLINQFIVTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTPELANQLLEDGVADMISMARP
FLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTASCLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTA
AERGHKITLFEKANQIGGQFNLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDISGQHRGGLKPPEIAPSPREV
YLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMFSGVNYERIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLK
MAGKLVHLIGGAYKALELDARHAIDQACRLAALV

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=667, Percent_Identity=57.1214392803598, Blast_Score=788, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=354, Percent_Identity=25.1412429378531, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=310, Percent_Identity=24.5161290322581, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540738, Length=310, Percent_Identity=24.1935483870968, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565138, Length=299, Percent_Identity=23.7458193979933, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564188, Length=307, Percent_Identity=22.8013029315961, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17566914, Length=306, Percent_Identity=24.5098039215686, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72001454, Length=339, Percent_Identity=22.1238938053097, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17559804, Length=317, Percent_Identity=23.0283911671924, Blast_Score=76, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=226, Percent_Identity=28.3185840707965, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=225, Percent_Identity=27.1111111111111, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 74619; Mature: 74619

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVG
CEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEE
LIVTGGFAPNRAGRLAPFAAKLTNSKEQHRHEVITQAVHEAGGKIALQILHAGRYGYHPF
EEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCE
IVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQLAGYDGVEIMGSEGYLINQFI
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEE
VTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
EECCCCCCHHCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCHHHHHH
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTP
HHHHHHHHCHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCH
ELANQLLEDGVADMISMARPFLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTAS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCHH
CLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTAAERGHKITLFEKANQIGGQF
HEECCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEECHHHCCCCE
NLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
EEHHCCCCHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDI
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCEE
SGQHRGGLKPPEIAPSPREVYLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMFSGVNYE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCEECCCCCHHHHHHHCCCCCE
RIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLKMAGKLVHLIGGAYKALELDA
EECCCCCEEEECCCCCEEEECEEEEEECCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RHAIDQACRLAALV
HHHHHHHHHHHHCC
>Mature Secondary Structure
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVG
CEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEE
LIVTGGFAPNRAGRLAPFAAKLTNSKEQHRHEVITQAVHEAGGKIALQILHAGRYGYHPF
EEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCE
IVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQLAGYDGVEIMGSEGYLINQFI
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEE
VTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
EECCCCCCHHCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCHHHHHH
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTP
HHHHHHHHCHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCH
ELANQLLEDGVADMISMARPFLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTAS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCHH
CLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTAAERGHKITLFEKANQIGGQF
HEECCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEECHHHCCCCE
NLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
EEHHCCCCHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDI
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCEE
SGQHRGGLKPPEIAPSPREVYLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMFSGVNYE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCEECCCCCHHHHHHHCCCCCE
RIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLKMAGKLVHLIGGAYKALELDA
EECCCCCEEEECCCCCEEEECEEEEEECCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RHAIDQACRLAALV
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]