Click here to switch to the map view.

The map label for this gene is lssX [H]

Identifier: 148359045

GI number: 148359045

Start: 1738097

End: 1738696

Strand: Direct

Name: lssX [H]

Synonym: LPC_0931

Alternate gene names: 148359045

Gene position: 1738097-1738696 (Clockwise)

Preceding gene: 148359044

Following gene: 148359046

Centisome position: 48.6

GC content: 38.0

Gene sequence:

>600_bases
ATGATAATTCATAATTTAGGCATAAAAGATTATACTGAAATATGGGAGCAGATGAAGGCGTTCACTGCAATCCGTGACAG
TAATTCTTGTGATGAGCTTTGGTTACTAGAGCATTACCCTGTATATACTCAGGGGCAGGCAGGGAAACCAGAGCATGTAC
TTAATCCCAACTCCATAAAAATTGTGCAATCTGATCGTGGTGGACAAGTTACATATCATGGCCCAGGCCAACTAGTAGCC
TATGTTTTAATGGATATTCGTCGCAGGAACCTGGGCATAAGAACTTTAGTAGCAAAACTGGAAGAAATATTAATTTCGGT
TTTAAAGCATTATAAAATTCCAGCAAACATTCGCAGTGGGGCACCTGGGGTTTACGTAGGTGAAAAAAAAATTGCATCGA
TAGGACTGAGGGTGAAAAATGGGTGTACCTATCATGGTATAGCATTAAATGTGAACATGGATTTGAGCCCATTCTTAGGT
ATTAACCCATGTGGTTTTGCTAAAATGGAAATGACACAGATGAGTCATTTCCATCCTAATATTCAGTTAGAGGAAGTAAG
CCAACATTTTGTACAGTATTTTTTGACTCAATTTAAATAA

Upstream 100 bases:

>100_bases
ATTTGGCTATTACTGTGACAGTATATGCAGAAAATCAAATCTCGCTGGATGGATTATATCAGGATTTAAGCCAACATCCG
GCTGTGAAAATGGTTTTATA

Downstream 100 bases:

>100_bases
TAGGAAATTATGAATTTGTTAGCAGATTATGTGCAACCACTGACTTATTGGCTACAAGCAAACCCACATTGGTCACTGTT
TATTACTTTCTTAATCGCTT

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIIHNLGIKDYTEIWEQMKAFTAIRDSNSCDELWLLEHYPVYTQGQAGKPEHVLNPNSIKIVQSDRGGQVTYHGPGQLVA
YVLMDIRRRNLGIRTLVAKLEEILISVLKHYKIPANIRSGAPGVYVGEKKIASIGLRVKNGCTYHGIALNVNMDLSPFLG
INPCGFAKMEMTQMSHFHPNIQLEEVSQHFVQYFLTQFK

Sequences:

>Translated_199_residues
MIIHNLGIKDYTEIWEQMKAFTAIRDSNSCDELWLLEHYPVYTQGQAGKPEHVLNPNSIKIVQSDRGGQVTYHGPGQLVA
YVLMDIRRRNLGIRTLVAKLEEILISVLKHYKIPANIRSGAPGVYVGEKKIASIGLRVKNGCTYHGIALNVNMDLSPFLG
INPCGFAKMEMTQMSHFHPNIQLEEVSQHFVQYFLTQFK
>Mature_199_residues
MIIHNLGIKDYTEIWEQMKAFTAIRDSNSCDELWLLEHYPVYTQGQAGKPEHVLNPNSIKIVQSDRGGQVTYHGPGQLVA
YVLMDIRRRNLGIRTLVAKLEEILISVLKHYKIPANIRSGAPGVYVGEKKIASIGLRVKNGCTYHGIALNVNMDLSPFLG
INPCGFAKMEMTQMSHFHPNIQLEEVSQHFVQYFLTQFK

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Homo sapiens, GI221554520, Length=168, Percent_Identity=34.5238095238095, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI87081767, Length=196, Percent_Identity=53.5714285714286, Blast_Score=238, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6323268, Length=183, Percent_Identity=32.2404371584699, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355483, Length=173, Percent_Identity=33.5260115606936, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 22554; Mature: 22554

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIHNLGIKDYTEIWEQMKAFTAIRDSNSCDELWLLEHYPVYTQGQAGKPEHVLNPNSIK
CEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCEE
IVQSDRGGQVTYHGPGQLVAYVLMDIRRRNLGIRTLVAKLEEILISVLKHYKIPANIRSG
EEECCCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
APGVYVGEKKIASIGLRVKNGCTYHGIALNVNMDLSPFLGINPCGFAKMEMTQMSHFHPN
CCCEEECCHHHHHCCEEECCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCC
IQLEEVSQHFVQYFLTQFK
CCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIHNLGIKDYTEIWEQMKAFTAIRDSNSCDELWLLEHYPVYTQGQAGKPEHVLNPNSIK
CEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCEE
IVQSDRGGQVTYHGPGQLVAYVLMDIRRRNLGIRTLVAKLEEILISVLKHYKIPANIRSG
EEECCCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
APGVYVGEKKIASIGLRVKNGCTYHGIALNVNMDLSPFLGINPCGFAKMEMTQMSHFHPN
CCCEEECCHHHHHCCEEECCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCC
IQLEEVSQHFVQYFLTQFK
CCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA