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The map label for this gene is ubiA [H]

Identifier: 148358961

GI number: 148358961

Start: 1645087

End: 1645935

Strand: Direct

Name: ubiA [H]

Synonym: LPC_0846

Alternate gene names: 148358961

Gene position: 1645087-1645935 (Clockwise)

Preceding gene: 148358960

Following gene: 148358973

Centisome position: 46.0

GC content: 33.57

Gene sequence:

>849_bases
ATGATTCCCTGGAATGCCTATGTCAGATTATTACGCTTAAATAAACCAATAGGAATTTTATTACTTTGGTATCCCACCGC
ATGGGCACTTTGGATGGCAAATCAGGGCTTTCCTTCTATTGATTTGCTTATGATTTTTTTATTCGGTACAGTATTCATGC
GTTCCGCAGGTTGTGTTATTAACGATATTGCTGACAGGCATATTGATAGGCATGTAGCCCGAACCCAATTTCGCCCCTTG
ACTTCTGGAGAGGTCAGCTTGTCTGAGGCATTTATTTTATTGTTTATATTACTTTGTGCCTCATTGCTTTTATTATTAAA
ACTTCCAATCAATTGTTTTTATTTTGCGGTTATTTCCGTGCTAATTACTTTTTTATACCCATTTTGTAAACGATTTTTGA
ATGCTCCACAGCTGATATTAGGCTTGGCTTTTTCCATGGGTATTCCTATGGCATTTATTGCCTCAGGAAAAAATTTAAAT
AGCGATTTTATTGTATTGTTTTTAATTAATTTCTCCTGGATTATCGCTTATGACACGATGTATGCGATGACTGACAAAGC
CGATGATTTAAAAATAGGAGTCAAATCGACTGCAATATATTTTGCAAGTTATGACAGATTAATTATTGCTTTGTTACTGA
TTTTTCTACATTCTTTATGGTTGGTATGGGCAATAAATAAGAACGCAGAATGGTTTTTTTATTTGTTATGGTGTACCGCT
GCTGGAATATTGACTTATCAACTAAAATTAATTTATGCAAGAATACCTAAAAATTGTTTTAAAGCATTTTTAGTGAGTGG
TTATTATGGATTAGTAATGTGGTTTGCTGTTGGATTAGCATTGATTTAA

Upstream 100 bases:

>100_bases
AATACTCTCAGATGTGGGTCAGGTTTACGGAGCTAGTATTTCAGGAAAAGAGTTCTTTTTATTTGGTTGAAATCTTGTTA
CCGGAGTTGGAAAGTTTATT

Downstream 100 bases:

>100_bases
ATAATATGTCCTCTCAACCCTAATATAAAATTTGTTGTGCCAAGAGATTATGGGTGTCGGAAAATTCCTTCATAAGACAG
GCTTTAGAAGAAAAAATCCA

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLFGTVFMRSAGCVINDIADRHIDRHVARTQFRPL
TSGEVSLSEAFILLFILLCASLLLLLKLPINCFYFAVISVLITFLYPFCKRFLNAPQLILGLAFSMGIPMAFIASGKNLN
SDFIVLFLINFSWIIAYDTMYAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNAEWFFYLLWCTA
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI

Sequences:

>Translated_282_residues
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLFGTVFMRSAGCVINDIADRHIDRHVARTQFRPL
TSGEVSLSEAFILLFILLCASLLLLLKLPINCFYFAVISVLITFLYPFCKRFLNAPQLILGLAFSMGIPMAFIASGKNLN
SDFIVLFLINFSWIIAYDTMYAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNAEWFFYLLWCTA
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI
>Mature_282_residues
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLFGTVFMRSAGCVINDIADRHIDRHVARTQFRPL
TSGEVSLSEAFILLFILLCASLLLLLKLPINCFYFAVISVLITFLYPFCKRFLNAPQLILGLAFSMGIPMAFIASGKNLN
SDFIVLFLINFSWIIAYDTMYAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNAEWFFYLLWCTA
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=2e-35,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=43.6363636363636, Blast_Score=224, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17553718, Length=272, Percent_Identity=32.7205882352941, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32565247, Length=276, Percent_Identity=31.1594202898551, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17553720, Length=181, Percent_Identity=36.4640883977901, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=40.4255319148936, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32565243, Length=138, Percent_Identity=40.5797101449275, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324370, Length=269, Percent_Identity=34.2007434944238, Blast_Score=145, Evalue=8e-36,
Organism=Drosophila melanogaster, GI21355567, Length=282, Percent_Identity=34.7517730496454, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32272; Mature: 32272

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLFGTVFMRSAGCVI
CCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHH
NDIADRHIDRHVARTQFRPLTSGEVSLSEAFILLFILLCASLLLLLKLPINCFYFAVISV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITFLYPFCKRFLNAPQLILGLAFSMGIPMAFIASGKNLNSDFIVLFLINFSWIIAYDTM
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHH
YAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNAEWFFYLLWCTA
HHHCCCCCCCEEEHHHHEEEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHH
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLFGTVFMRSAGCVI
CCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHH
NDIADRHIDRHVARTQFRPLTSGEVSLSEAFILLFILLCASLLLLLKLPINCFYFAVISV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITFLYPFCKRFLNAPQLILGLAFSMGIPMAFIASGKNLNSDFIVLFLINFSWIIAYDTM
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHH
YAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNAEWFFYLLWCTA
HHHCCCCCCCEEEHHHHEEEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHH
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA