BacMap

Definition	Legionella pneumophila str. Corby chromosome, complete genome.
Accession	NC_009494
Length	3,576,470

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The map label for this gene is ucpA [H]

Identifier: 148358958

GI number: 148358958

Start: 1643171

End: 1643950

Strand: Direct

Name: ucpA [H]

Synonym: LPC_0843

Alternate gene names: 148358958

Gene position: 1643171-1643950 (Clockwise)

Preceding gene: 148358957

Following gene: 148358959

Centisome position: 45.94

GC content: 37.31

Gene sequence:

>780_bases
ATGATGACCTTAATAACGGGGGCCACGAGAGGTATAGGCTTGGCCTTGGCGTATGAGTTTGCATCACATGGCCATGATTT
AATACTTATTGGTAGAGATTCTGAACAGCTGGAGCACATTTCAAAGCAATTAAATACACAATATCAAGTTAATGTTGAAT
ATAAAGTACATGACTTAAGTAAACCTGGAAGCGCATTTAAGTTGTATACTGATTTAAAGGAGCAGGGTATAGAAGTCAAC
TGCCTGGTTAATAATGCGGGCATAGGCTATATGGGTTCTTTTGTTGAAATGGGCATGAACAAGCTCGATGATTTAATGAA
CATAAACATGATTTCTTTAAGTGAATTAACACTATGTTTTCTTCATGATTTTGTAGCTCGTAACGAAGGCAGTATTTTAC
AGGTTTCTTCAACAGCAGCATTTCAACCGGGTCCTTTTATGGCAGCCTACTATGCGAGTAAGGCATATGTAGCAACGCTT
TCTCATGCTATTGCTTATGAGCTTAAAGATACTAAGGTATCTATGTCTATTCTTTGTCCTGGAGCAACAAAAACCAATTT
TTTCCATGCTTCTGGTATGGAAAATTCTATGTTGGAGAGGGGATATATTGGAATGATGACCCCTGAAAAGGTCGCTAAAA
TTGCTTATAAAGGACTAAAAAAAGGAAAGTTGTATATTATTCCGGGGCTAAGAAATAAAATTTTAGCCTATGCCGCAGCT
ATATCACCCAAAGCGATTGCTCTTAGGATCGCATCTTATCTTCATCATAAAATTTTGTAG

Upstream 100 bases:

>100_bases
AATTTGTTAAAACAGGAAAAGCATGACGATGTATCTCGGCAATTGGATTGCCTACGTAACCAAATGGAGCCTGTGCAAAC
AGTAAAAGGAGGAGTGCATC

Downstream 100 bases:

>100_bases
ATGATATGCGGCTTCAATTGATGAAAATAACAGGATTTACTCTACTTGAAACGATGCTTACATTAGCTTTGCTTTTAGGA
TTATTGCTTTTAGGTTCATG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MMTLITGATRGIGLALAYEFASHGHDLILIGRDSEQLEHISKQLNTQYQVNVEYKVHDLSKPGSAFKLYTDLKEQGIEVN
CLVNNAGIGYMGSFVEMGMNKLDDLMNINMISLSELTLCFLHDFVARNEGSILQVSSTAAFQPGPFMAAYYASKAYVATL
SHAIAYELKDTKVSMSILCPGATKTNFFHASGMENSMLERGYIGMMTPEKVAKIAYKGLKKGKLYIIPGLRNKILAYAAA
ISPKAIALRIASYLHHKIL

Sequences:

>Translated_259_residues
MMTLITGATRGIGLALAYEFASHGHDLILIGRDSEQLEHISKQLNTQYQVNVEYKVHDLSKPGSAFKLYTDLKEQGIEVN
CLVNNAGIGYMGSFVEMGMNKLDDLMNINMISLSELTLCFLHDFVARNEGSILQVSSTAAFQPGPFMAAYYASKAYVATL
SHAIAYELKDTKVSMSILCPGATKTNFFHASGMENSMLERGYIGMMTPEKVAKIAYKGLKKGKLYIIPGLRNKILAYAAA
ISPKAIALRIASYLHHKIL
>Mature_259_residues
MMTLITGATRGIGLALAYEFASHGHDLILIGRDSEQLEHISKQLNTQYQVNVEYKVHDLSKPGSAFKLYTDLKEQGIEVN
CLVNNAGIGYMGSFVEMGMNKLDDLMNINMISLSELTLCFLHDFVARNEGSILQVSSTAAFQPGPFMAAYYASKAYVATL
SHAIAYELKDTKVSMSILCPGATKTNFFHASGMENSMLERGYIGMMTPEKVAKIAYKGLKKGKLYIIPGLRNKILAYAAA
ISPKAIALRIASYLHHKIL

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI226371731, Length=198, Percent_Identity=33.8383838383838, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI7705855, Length=218, Percent_Identity=27.9816513761468, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4557649, Length=186, Percent_Identity=32.7956989247312, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI20149619, Length=252, Percent_Identity=26.984126984127, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI32483357, Length=220, Percent_Identity=28.6363636363636, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI142976729, Length=232, Percent_Identity=28.8793103448276, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI210032110, Length=250, Percent_Identity=24, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=25.1282051282051, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI109715829, Length=223, Percent_Identity=23.3183856502242, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=221, Percent_Identity=24.8868778280543, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031737, Length=194, Percent_Identity=26.2886597938144, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=183, Percent_Identity=32.2404371584699, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787820, Length=221, Percent_Identity=26.2443438914027, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787335, Length=189, Percent_Identity=25.3968253968254, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786812, Length=183, Percent_Identity=28.4153005464481, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082160, Length=186, Percent_Identity=24.7311827956989, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789208, Length=188, Percent_Identity=26.063829787234, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=211, Percent_Identity=29.8578199052133, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25152911, Length=203, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=201, Percent_Identity=29.8507462686567, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=251, Percent_Identity=28.6852589641434, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=198, Percent_Identity=30.3030303030303, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=208, Percent_Identity=29.8076923076923, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=243, Percent_Identity=27.1604938271605, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17557668, Length=202, Percent_Identity=25.2475247524752, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=249, Percent_Identity=26.5060240963855, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560176, Length=193, Percent_Identity=25.9067357512953, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17559552, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=206, Percent_Identity=28.1553398058252, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=247, Percent_Identity=27.9352226720648, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI212646214, Length=202, Percent_Identity=25.2475247524752, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=187, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532725, Length=213, Percent_Identity=26.7605633802817, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=247, Percent_Identity=25.9109311740891, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=31.25, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319635, Length=222, Percent_Identity=26.5765765765766, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076933, Length=184, Percent_Identity=32.0652173913043, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24584748, Length=184, Percent_Identity=32.0652173913043, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574402, Length=201, Percent_Identity=30.8457711442786, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24584744, Length=201, Percent_Identity=30.8457711442786, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24644339, Length=193, Percent_Identity=31.6062176165803, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24640442, Length=190, Percent_Identity=34.2105263157895, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24584752, Length=198, Percent_Identity=29.2929292929293, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=29.8429319371728, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=31.1475409836066, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21356301, Length=286, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357041, Length=200, Percent_Identity=28, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580925, Length=198, Percent_Identity=28.2828282828283, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21358495, Length=251, Percent_Identity=27.0916334661355, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28471; Mature: 28471

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLITGATRGIGLALAYEFASHGHDLILIGRDSEQLEHISKQLNTQYQVNVEYKVHDLS
CEEEEECCCCCCHHEEEEEHHHCCCEEEEEECCHHHHHHHHHHHCCEEEEEEEEEEEECC
KPGSAFKLYTDLKEQGIEVNCLVNNAGIGYMGSFVEMGMNKLDDLMNINMISLSELTLCF
CCCCEEEEEEHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
LHDFVARNEGSILQVSSTAAFQPGPFMAAYYASKAYVATLSHAIAYELKDTKVSMSILCP
HHHHHHCCCCCEEEEECCCCCCCCCCEEEHHHCHHHHHHHHHHHHEEECCCEEEEEEEEC
GATKTNFFHASGMENSMLERGYIGMMTPEKVAKIAYKGLKKGKLYIIPGLRNKILAYAAA
CCCCCCEEECCCCCCHHHHCCCEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHH
ISPKAIALRIASYLHHKIL
CCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMTLITGATRGIGLALAYEFASHGHDLILIGRDSEQLEHISKQLNTQYQVNVEYKVHDLS
CEEEEECCCCCCHHEEEEEHHHCCCEEEEEECCHHHHHHHHHHHCCEEEEEEEEEEEECC
KPGSAFKLYTDLKEQGIEVNCLVNNAGIGYMGSFVEMGMNKLDDLMNINMISLSELTLCF
CCCCEEEEEEHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
LHDFVARNEGSILQVSSTAAFQPGPFMAAYYASKAYVATLSHAIAYELKDTKVSMSILCP
HHHHHHCCCCCEEEEECCCCCCCCCCEEEHHHCHHHHHHHHHHHHEEECCCEEEEEEEEC
GATKTNFFHASGMENSMLERGYIGMMTPEKVAKIAYKGLKKGKLYIIPGLRNKILAYAAA
CCCCCCEEECCCCCCHHHHCCCEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHH
ISPKAIALRIASYLHHKIL
CCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]