Click here to switch to the map view.

The map label for this gene is argE [H]

Identifier: 148358750

GI number: 148358750

Start: 1407469

End: 1408623

Strand: Direct

Name: argE [H]

Synonym: LPC_0629

Alternate gene names: 148358750

Gene position: 1407469-1408623 (Clockwise)

Preceding gene: 148358749

Following gene: 148358751

Centisome position: 39.35

GC content: 38.01

Gene sequence:

>1155_bases
ATGACAACTTTAGATTGGTTAAAACAACTCATTTCTTTTGATACTACTTCGCGGAACTCTAATTTATCATTGATTGAATA
TTTGGCGAATGGGTTAAATGATTTCAAGATTAATCCTATCCTAATTCACGATAATAAAGAGCAGAAAGCTAATCTGTTAG
CTACTTTGCCAGGAAAACAAGGGCGTTTGGAAGGGGGTATTATTCTGTCTGGTCATACTGATGTTGTTCCTGTTGACGGT
CAAATTTGGGATAGTGATCCTTTTCAAGCCACTCTTAAAAATAACAAAGTGTATGGTCGTGGCGCGTGTGATATGAAAGG
ATTTATTGCAGTCGTGATGGCTTTAGTCCCACAATTGAAAGAAATGAATCTGGACTTTCCAGTTCATTTTGCATTTTCTT
ATGATGAGGAAATTGGTTGTCTTGGTGTACCTTCTCTGATCGATAAAATAGTGGAGCTTAATTATCAACCGCGTGCCTGC
ATTGTAGGTGAGCCAACCTTAATGAAGCCTGTTGTGGGTCATAAAGGCAAATATTCCTATCGCTGCCAAATACATGGTGT
AGCTGCTCACTCTTCATTAACGAATCAAGGATGTAATGCGATCGAACATGCCGCGTCTTTTATAAGCTATCTTCGAGGGA
TGGCTAATGAATTTAAAAAATATGGAAATCGAGATTTTTCTTATGATGTTCCATATACAACACTTACCACCAATCTGATC
AAAGGAGGTAATGCTTATAATACTATTCCAAACTTGTGTGAGTTTGTTTTTGAGTTTAGAAATCTGTCTACTGATAGCTC
TGAGGATTTAAATCAGAAAATTATGTCTTATGTTAAGGAACAGCTTGTTCCTAACCTGCATCAGGATCATCCTGACTCTA
ATGTTAATCTTGATACCATAGCAAAAGCTCCTGGTTTGGATATGCCGATTACAGATCCTTTTGTCAGAGCAGCTCAAACA
GTTTGCCAGAGCGATAAACTGATGAAAGTAGCTTACGCTACAGAAGCCGGGCTATTTCAACAGGCAGAAATTCCCACTAT
TGTGTGTGGTCCAGGTAGTATCGAACAAGCCCATAGAGCAAATGAATATGTTGAAGTAGAGCAATTACGATTATGTGAGG
AATTTATAATCAATATGCTGCGCTCTCATTTTTGA

Upstream 100 bases:

>100_bases
CGGTCTTTATCAGTTTGCTAGCAGTCCTTTCTTATCAGGAGGAAAGGAAGCTATCTGAGAATCAGCCAGAACATCTCGTT
GCAATTTAAAAGGTAGGAAT

Downstream 100 bases:

>100_bases
GCTTTATCAGATTGGTAAGTAAAAAATCATCGGTATTTGATGCTGATTTTACTAGCACTTTTATAAGGTATTCACAAAGA
TATACACAGTTTTTGTGGAT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDNKEQKANLLATLPGKQGRLEGGIILSGHTDVVPVDG
QIWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLKEMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRAC
IVGEPTLMKPVVGHKGKYSYRCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEQLVPNLHQDHPDSNVNLDTIAKAPGLDMPITDPFVRAAQT
VCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRANEYVEVEQLRLCEEFIINMLRSHF

Sequences:

>Translated_384_residues
MTTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDNKEQKANLLATLPGKQGRLEGGIILSGHTDVVPVDG
QIWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLKEMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRAC
IVGEPTLMKPVVGHKGKYSYRCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEQLVPNLHQDHPDSNVNLDTIAKAPGLDMPITDPFVRAAQT
VCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRANEYVEVEQLRLCEEFIINMLRSHF
>Mature_383_residues
TTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDNKEQKANLLATLPGKQGRLEGGIILSGHTDVVPVDGQ
IWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLKEMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRACI
VGEPTLMKPVVGHKGKYSYRCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLIK
GGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEQLVPNLHQDHPDSNVNLDTIAKAPGLDMPITDPFVRAAQTV
CQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRANEYVEVEQLRLCEEFIINMLRSHF

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=374, Percent_Identity=32.620320855615, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788816, Length=230, Percent_Identity=29.5652173913043, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24649206, Length=296, Percent_Identity=22.6351351351351, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42802; Mature: 42671

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDNKEQKANLLATLPGKQ
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHCCEEEECCCCC
GRLEGGIILSGHTDVVPVDGQIWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLK
CCCCCCEEEECCCCEEECCCEECCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHH
EMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRACIVGEPTLMKPVVGHKGKYSY
HCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCEEE
RCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
EEEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEQLVPNLHQDHPDSNVNLDTI
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
AKAPGLDMPITDPFVRAAQTVCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRA
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCEEEECCCCHHHHHHH
NEYVEVEQLRLCEEFIINMLRSHF
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDNKEQKANLLATLPGKQ
CHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHCCEEEECCCCC
GRLEGGIILSGHTDVVPVDGQIWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLK
CCCCCCEEEECCCCEEECCCEECCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHH
EMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRACIVGEPTLMKPVVGHKGKYSY
HCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCEEE
RCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
EEEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEQLVPNLHQDHPDSNVNLDTI
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
AKAPGLDMPITDPFVRAAQTVCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRA
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCEEEECCCCHHHHHHH
NEYVEVEQLRLCEEFIINMLRSHF
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]