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The map label for this gene is intR [H]

Identifier: 148358336

GI number: 148358336

Start: 213091

End: 214170

Strand: Direct

Name: intR [H]

Synonym: LPC_0199

Alternate gene names: 148358336

Gene position: 213091-214170 (Clockwise)

Preceding gene: 148358335

Following gene: 148358339

Centisome position: 5.96

GC content: 38.15

Gene sequence:

>1080_bases
TTGAAAATTGAACCAACCAAGGCAAATATAAAATATGCCGAAAGGTTAAGGGGTGAAATTCTAAACGCCATTAGTCTGGG
GACGTTTAATTATCAGGATTATTTCCCAAACTCACAACGGTCAAAAATGTTTGGTTTTTCAGTAGTGAAATCTACTGTGG
GTGAATTGCTCAAACAATATATGGAAATTGCTGAAAAAACACTTGAACCCAGTACCTTTAATGGCTATAGAAAGGCATGC
GAAGCTCATTTATACCCGGCATTTGGTGATATTCCTGTAAAAGATTTGTCATCTATGATGATTCGTAATTATGTGACAAA
GCTTCAATTGACGCTTAAAACCATACGAAATATTTTAACCCCTTTGAGAAATACTTTAGATCAGGCATTAAATGATGGCA
TGATTACATCCAACCCGTTGGATAGATTGGTATTATCTAAGTTGGTTGATAAAAAAACTCGCAGGAGTAATTGGGAGGTT
GATCCATTTAATCAAGATGAAATTAAAGCCATTCTTTCTGAAGCAAAAGGTCAAGCCAGGAATCTATTCCAATTCGCTTT
TTATAGTGGCTTACGAACATCGGAGCTTATCGCTTTAGAATGGGGCGATATTGATTGGTTAAATGGGATTGTGAGGGTAT
CAAGAGCCGTGGTTCTAAAAAAAGAAAAAGGTACTAAGACTAAATCAGGCCAACGTGACGTACTGTTACTTCCACCAGCA
TTAGAAGCTCTGCAAAATCAAAAGAAATTTACTTTTCTTGAAGGGGGTCGTGTGTTTTATAACCCTCGCACCAATACCCC
CTGGGAAACAGACGGTCAAATTCGAAAAACCTGCTGGGCACATATATTAAAAAAAGCAGGGGTTCGCTACCGCAACCCTT
ATCAAACACGCCATACTTATGCATCGATGATGCTCTCTGCTGGCGAAAATTCTTTATGGGTTGCTAAGCAAATGGGACAT
AAAGATACAGAGATGATTATCAAAAATTATGGCAGATGGATTCCTGATACATCTACTTTAGCAGGATATACAACAGTCAA
TGACTGGTCCTCACCATTGACTGGCGTAGTAAAAAAATAG

Upstream 100 bases:

>100_bases
CGAATATCCGGTTGCGCGCGGGATAAGTGTTAGAGAACTTGATTCCAGTAAATGTATTAGAATCGATTTTACTTATCGTG
GTGTTAGATGTCGTGAAACG

Downstream 100 bases:

>100_bases
CATTATCAGTCTGCACCTTTCCATGACTCGCCAGGTAAAGAAGAAAGAAACTTTTCTTTTATATGCTTTGCTGCATAATT
AATGTCCCAGCTTAAACCAG

Product: putative lambdoid prophage Rac integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKIEPTKANIKYAERLRGEILNAISLGTFNYQDYFPNSQRSKMFGFSVVKSTVGELLKQYMEIAEKTLEPSTFNGYRKAC
EAHLYPAFGDIPVKDLSSMMIRNYVTKLQLTLKTIRNILTPLRNTLDQALNDGMITSNPLDRLVLSKLVDKKTRRSNWEV
DPFNQDEIKAILSEAKGQARNLFQFAFYSGLRTSELIALEWGDIDWLNGIVRVSRAVVLKKEKGTKTKSGQRDVLLLPPA
LEALQNQKKFTFLEGGRVFYNPRTNTPWETDGQIRKTCWAHILKKAGVRYRNPYQTRHTYASMMLSAGENSLWVAKQMGH
KDTEMIIKNYGRWIPDTSTLAGYTTVNDWSSPLTGVVKK

Sequences:

>Translated_359_residues
MKIEPTKANIKYAERLRGEILNAISLGTFNYQDYFPNSQRSKMFGFSVVKSTVGELLKQYMEIAEKTLEPSTFNGYRKAC
EAHLYPAFGDIPVKDLSSMMIRNYVTKLQLTLKTIRNILTPLRNTLDQALNDGMITSNPLDRLVLSKLVDKKTRRSNWEV
DPFNQDEIKAILSEAKGQARNLFQFAFYSGLRTSELIALEWGDIDWLNGIVRVSRAVVLKKEKGTKTKSGQRDVLLLPPA
LEALQNQKKFTFLEGGRVFYNPRTNTPWETDGQIRKTCWAHILKKAGVRYRNPYQTRHTYASMMLSAGENSLWVAKQMGH
KDTEMIIKNYGRWIPDTSTLAGYTTVNDWSSPLTGVVKK
>Mature_359_residues
MKIEPTKANIKYAERLRGEILNAISLGTFNYQDYFPNSQRSKMFGFSVVKSTVGELLKQYMEIAEKTLEPSTFNGYRKAC
EAHLYPAFGDIPVKDLSSMMIRNYVTKLQLTLKTIRNILTPLRNTLDQALNDGMITSNPLDRLVLSKLVDKKTRRSNWEV
DPFNQDEIKAILSEAKGQARNLFQFAFYSGLRTSELIALEWGDIDWLNGIVRVSRAVVLKKEKGTKTKSGQRDVLLLPPA
LEALQNQKKFTFLEGGRVFYNPRTNTPWETDGQIRKTCWAHILKKAGVRYRNPYQTRHTYASMMLSAGENSLWVAKQMGH
KDTEMIIKNYGRWIPDTSTLAGYTTVNDWSSPLTGVVKK

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1787607, Length=373, Percent_Identity=33.5120643431635, Blast_Score=171, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR022000
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF12167 DUF3596; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 41023; Mature: 41023

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEPTKANIKYAERLRGEILNAISLGTFNYQDYFPNSQRSKMFGFSVVKSTVGELLKQY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
MEIAEKTLEPSTFNGYRKACEAHLYPAFGDIPVKDLSSMMIRNYVTKLQLTLKTIRNILT
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLRNTLDQALNDGMITSNPLDRLVLSKLVDKKTRRSNWEVDPFNQDEIKAILSEAKGQAR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHH
NLFQFAFYSGLRTSELIALEWGDIDWLNGIVRVSRAVVLKKEKGTKTKSGQRDVLLLPPA
HHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEECHH
LEALQNQKKFTFLEGGRVFYNPRTNTPWETDGQIRKTCWAHILKKAGVRYRNPYQTRHTY
HHHHCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ASMMLSAGENSLWVAKQMGHKDTEMIIKNYGRWIPDTSTLAGYTTVNDWSSPLTGVVKK
HHHHHHCCCCCEEHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MKIEPTKANIKYAERLRGEILNAISLGTFNYQDYFPNSQRSKMFGFSVVKSTVGELLKQY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
MEIAEKTLEPSTFNGYRKACEAHLYPAFGDIPVKDLSSMMIRNYVTKLQLTLKTIRNILT
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLRNTLDQALNDGMITSNPLDRLVLSKLVDKKTRRSNWEVDPFNQDEIKAILSEAKGQAR
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHH
NLFQFAFYSGLRTSELIALEWGDIDWLNGIVRVSRAVVLKKEKGTKTKSGQRDVLLLPPA
HHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEECHH
LEALQNQKKFTFLEGGRVFYNPRTNTPWETDGQIRKTCWAHILKKAGVRYRNPYQTRHTY
HHHHCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ASMMLSAGENSLWVAKQMGHKDTEMIIKNYGRWIPDTSTLAGYTTVNDWSSPLTGVVKK
HHHHHHCCCCCEEHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]