Click here to switch to the map view.

The map label for this gene is nuoG [H]

Identifier: 148285161

GI number: 148285161

Start: 2103155

End: 2105194

Strand: Direct

Name: nuoG [H]

Synonym: OTBS_2159

Alternate gene names: 148285161

Gene position: 2103155-2105194 (Clockwise)

Preceding gene: 148285159

Following gene: 148285162

Centisome position: 98.88

GC content: 31.81

Gene sequence:

>2040_bases
ATGGTTAACCTGATAATTAATAATAAAAAAGTTAAAATTAAAGACGAAATAACAATTATTCAAGCTTGTGAGTTATTGAA
TATCGAAGTGCCAAGATTTTGCTATCACGAACGTTTGGCTATAGCTGGTAATTGTAGAATGTGCTTAGTTGAAATTGAAA
GTTCTCCTAAGTTAGTAGCTTCATGTGCGATGCTTATATCAGATGGTATGGTAATTCATACAAATTCTCCAAGAGTTGAA
AAAGCTCGAAAAAGTGTTATGGAATTTTTATTAATTAATCATCCACTAGATTGTCCAGTTTGTGATCAAGGTGGAGAATG
CGATTTACAGGATCAAGCATTTAAATATGGTAGTCAAGTTAGCCGCTTTAATGAAAATAAACGCATAGTTAAAGATAAAT
ATATGGGTCCATTAATTGCAACTCATATGACACGGTGTATTCACTGTACTAGATGTATTAGATTTGCTCAAGATATAGCT
GGGCTACCAGAAATAGGAGCTATTGGCAGAGGAGAAAATATGGAAGTACAGACTTATTTAGAGAAAAGTATGAAATCTGA
ATTGTCTGGTAATGTAATTGATCTTTGCCCAGTTGGGGCATTGAATTCTAAGCCTTATGCTTGTACAGCAAGGTCATGGG
AATTAACATATACTGAATCAGTTGATGTATTTGATGCTATGGGATCGAATATTAAGATAAATTCTCGTGGTTTAGAGGTA
ATGCGAATTTTGCCATCTTATTGTGATGAAATTAATGAAGAATGGATATCTGATAAAACTAGGTTTTCTTATGATGGGCT
AAAATATCAGCGTCTTGATAGGCCATATATAAAAAAAAATGGCAGATTGCAAGAAGCAAGCTGGAATGATGCTGTAGAAT
ATATAGCTGACAAGATGAGAAAAACTCCTGGAGACAAAATGGCTGCTATTGCTGGTACTATGGTAGATTGTGAATCAATG
TTTGCTCTGAAATTATTGATGCAAAATTTTGGCTGTAATAATTTTGATACCAATCAATTTAATTATAAATTGGACATTAG
CTCTAGGGGCAATTATTTATTTAATACCTCGATTGCTGGAGTTGATTTTTCGGATTTATGTTTGTTGGTTGGTGTTGATA
TGAATTTTTCTGCTCCAGTTCTTGGAGCGAGGTTAACAAGATTACAACGTTGGAAGAAACTAAAAATATTAAATATTGGC
CCAGAAAATTATGAGCACAGATTTAATGTGATTAACATAGGGAATAGCCCTAGTTTATTAGTTGATATTTTAAGTGGTAA
CCACAAAATTATAAATGAAATTAATAGCGCTAAAAATCCGATGATAATTATTGGTGACTTAGCTTATGCTCGTGATGATG
GTTTAAAAGTTCTTGAATTATGTCAAAATATTGCTTACAAGTATAATTTTATTCGACAAAATTGGAATGGGTATAATATT
TTACATAATCATGCTTCGACTGTTGGAGCTATTGATTTGGGATTTTTTGCAGATAGTAATAGTAAAAATGTAACTAAAAT
TTTAAATGGCTGCGAACAAGGAGAAATATCATTAGTTTATTTGTTAGGGGCTGATGAGCTTGATACAAGTAAGCTAAGTA
ATGCTTTTGTTATTTATCAAGGACATCATGGTGATATAGGCGCTAACTGTGCTGATGTAGTATTGCCTGGAGCAGCATAT
ACTGAAAAAAATGCTATTTATGTTAATTTTGAGGGTAGGGCGCAATATGCTAGACAAGCAGTTGCTAAAGTAGGTTCAGC
TAAAGATGATTGGTTAATTATCAAAAATATATCGGATAAAGTAAAATCTAAATTTTACTTTAAGGATCTATATGATTTAA
GAAGTCAAGCTGCTAAAGTTGCTAAATCATTAAGAAATATTGGTAATATACAAAAAAGCAGCGTAAAAAAGATTAAAAGT
GATATCATATTAAATACGGAAGAAGTATTTGCTTTAAAGAAACGCAATTTTTATATTACTGATGTAATTACTAGAGTATC
ACCAGTTATGGCAGAATGTACAAAAGTACAAAAAGGATAA

Upstream 100 bases:

>100_bases
AAGCGCGAATTAATTCACGAATTCCAAGAAATTAGTTTACTGCTGAAAGCTTAAGTTCTATAATCGATAAGTGGTTATTT
TATAACATATATTTATTTTA

Downstream 100 bases:

>100_bases
TATTAGAGTTAAAGTTAAATCTTGTACATTAAATAAAAAATAATAATTATGACTATATGACTATCTGTACAGATATAATT
GCCAATGGCTATGATTTAAA

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 679; Mature: 679

Protein sequence:

>679_residues
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIESSPKLVASCAMLISDGMVIHTNSPRVE
KARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQVSRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIA
GLPEIGAIGRGENMEVQTYLEKSMKSELSGNVIDLCPVGALNSKPYACTARSWELTYTESVDVFDAMGSNIKINSRGLEV
MRILPSYCDEINEEWISDKTRFSYDGLKYQRLDRPYIKKNGRLQEASWNDAVEYIADKMRKTPGDKMAAIAGTMVDCESM
FALKLLMQNFGCNNFDTNQFNYKLDISSRGNYLFNTSIAGVDFSDLCLLVGVDMNFSAPVLGARLTRLQRWKKLKILNIG
PENYEHRFNVINIGNSPSLLVDILSGNHKIINEINSAKNPMIIIGDLAYARDDGLKVLELCQNIAYKYNFIRQNWNGYNI
LHNHASTVGAIDLGFFADSNSKNVTKILNGCEQGEISLVYLLGADELDTSKLSNAFVIYQGHHGDIGANCADVVLPGAAY
TEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDKVKSKFYFKDLYDLRSQAAKVAKSLRNIGNIQKSSVKKIKS
DIILNTEEVFALKKRNFYITDVITRVSPVMAECTKVQKG

Sequences:

>Translated_679_residues
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIESSPKLVASCAMLISDGMVIHTNSPRVE
KARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQVSRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIA
GLPEIGAIGRGENMEVQTYLEKSMKSELSGNVIDLCPVGALNSKPYACTARSWELTYTESVDVFDAMGSNIKINSRGLEV
MRILPSYCDEINEEWISDKTRFSYDGLKYQRLDRPYIKKNGRLQEASWNDAVEYIADKMRKTPGDKMAAIAGTMVDCESM
FALKLLMQNFGCNNFDTNQFNYKLDISSRGNYLFNTSIAGVDFSDLCLLVGVDMNFSAPVLGARLTRLQRWKKLKILNIG
PENYEHRFNVINIGNSPSLLVDILSGNHKIINEINSAKNPMIIIGDLAYARDDGLKVLELCQNIAYKYNFIRQNWNGYNI
LHNHASTVGAIDLGFFADSNSKNVTKILNGCEQGEISLVYLLGADELDTSKLSNAFVIYQGHHGDIGANCADVVLPGAAY
TEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDKVKSKFYFKDLYDLRSQAAKVAKSLRNIGNIQKSSVKKIKS
DIILNTEEVFALKKRNFYITDVITRVSPVMAECTKVQKG
>Mature_679_residues
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIESSPKLVASCAMLISDGMVIHTNSPRVE
KARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQVSRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIA
GLPEIGAIGRGENMEVQTYLEKSMKSELSGNVIDLCPVGALNSKPYACTARSWELTYTESVDVFDAMGSNIKINSRGLEV
MRILPSYCDEINEEWISDKTRFSYDGLKYQRLDRPYIKKNGRLQEASWNDAVEYIADKMRKTPGDKMAAIAGTMVDCESM
FALKLLMQNFGCNNFDTNQFNYKLDISSRGNYLFNTSIAGVDFSDLCLLVGVDMNFSAPVLGARLTRLQRWKKLKILNIG
PENYEHRFNVINIGNSPSLLVDILSGNHKIINEINSAKNPMIIIGDLAYARDDGLKVLELCQNIAYKYNFIRQNWNGYNI
LHNHASTVGAIDLGFFADSNSKNVTKILNGCEQGEISLVYLLGADELDTSKLSNAFVIYQGHHGDIGANCADVVLPGAAY
TEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDKVKSKFYFKDLYDLRSQAAKVAKSLRNIGNIQKSSVKKIKS
DIILNTEEVFALKKRNFYITDVITRVSPVMAECTKVQKG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=697, Percent_Identity=46.4849354375897, Blast_Score=622, Evalue=1e-178,
Organism=Escherichia coli, GI145693161, Length=645, Percent_Identity=24.8062015503876, Blast_Score=203, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17565758, Length=696, Percent_Identity=44.3965517241379, Blast_Score=577, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI32566231, Length=597, Percent_Identity=47.4036850921273, Blast_Score=545, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI193209088, Length=251, Percent_Identity=58.1673306772908, Blast_Score=322, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24640559, Length=691, Percent_Identity=42.9811866859624, Blast_Score=576, Evalue=1e-164,
Organism=Drosophila melanogaster, GI24640557, Length=691, Percent_Identity=42.9811866859624, Blast_Score=576, Evalue=1e-164,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 76219; Mature: 76219

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIESSPKLVA
CEEEEEECCEEEEECCEEHEEHHHHHCCCCCHHHHHCCEEEECCCEEEEEEECCCCHHHH
SCAMLISDGMVIHTNSPRVEKARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQV
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
SRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIAGLPEIGAIGRGENMEVQTYL
HHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
EKSMKSELSGNVIDLCPVGALNSKPYACTARSWELTYTESVDVFDAMGSNIKINSRGLEV
HHHHHHHHCCCEEEECCCCCCCCCCCEEECCCEEEEEECCCHHHHHCCCCEEECCCCHHH
MRILPSYCDEINEEWISDKTRFSYDGLKYQRLDRPYIKKNGRLQEASWNDAVEYIADKMR
HHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCHHHCCCEEECCCHHHHHHHHHHHHH
KTPGDKMAAIAGTMVDCESMFALKLLMQNFGCNNFDTNQFNYKLDISSRGNYLFNTSIAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEECEECC
VDFSDLCLLVGVDMNFSAPVLGARLTRLQRWKKLKILNIGPENYEHRFNVINIGNSPSLL
CCHHHEEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEECCCCCCCCEEEEEEECCCCCEE
VDILSGNHKIINEINSAKNPMIIIGDLAYARDDGLKVLELCQNIAYKYNFIRQNWNGYNI
EEEECCCHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
LHNHASTVGAIDLGFFADSNSKNVTKILNGCEQGEISLVYLLGADELDTSKLSNAFVIYQ
EECCCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCEEEEEE
GHHGDIGANCADVVLPGAAYTEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDK
CCCCCCCCCHHHEEECCCCEECCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHH
VKSKFYFKDLYDLRSQAAKVAKSLRNIGNIQKSSVKKIKSDIILNTEEVFALKKRNFYIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECHHHHHHHHCCCEEHH
DVITRVSPVMAECTKVQKG
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNLIINNKKVKIKDEITIIQACELLNIEVPRFCYHERLAIAGNCRMCLVEIESSPKLVA
CEEEEEECCEEEEECCEEHEEHHHHHCCCCCHHHHHCCEEEECCCEEEEEEECCCCHHHH
SCAMLISDGMVIHTNSPRVEKARKSVMEFLLINHPLDCPVCDQGGECDLQDQAFKYGSQV
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
SRFNENKRIVKDKYMGPLIATHMTRCIHCTRCIRFAQDIAGLPEIGAIGRGENMEVQTYL
HHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
EKSMKSELSGNVIDLCPVGALNSKPYACTARSWELTYTESVDVFDAMGSNIKINSRGLEV
HHHHHHHHCCCEEEECCCCCCCCCCCEEECCCEEEEEECCCHHHHHCCCCEEECCCCHHH
MRILPSYCDEINEEWISDKTRFSYDGLKYQRLDRPYIKKNGRLQEASWNDAVEYIADKMR
HHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCHHHCCCEEECCCHHHHHHHHHHHHH
KTPGDKMAAIAGTMVDCESMFALKLLMQNFGCNNFDTNQFNYKLDISSRGNYLFNTSIAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEECEECC
VDFSDLCLLVGVDMNFSAPVLGARLTRLQRWKKLKILNIGPENYEHRFNVINIGNSPSLL
CCHHHEEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEECCCCCCCCEEEEEEECCCCCEE
VDILSGNHKIINEINSAKNPMIIIGDLAYARDDGLKVLELCQNIAYKYNFIRQNWNGYNI
EEEECCCHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
LHNHASTVGAIDLGFFADSNSKNVTKILNGCEQGEISLVYLLGADELDTSKLSNAFVIYQ
EECCCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCEEEEEE
GHHGDIGANCADVVLPGAAYTEKNAIYVNFEGRAQYARQAVAKVGSAKDDWLIIKNISDK
CCCCCCCCCHHHEEECCCCEECCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHH
VKSKFYFKDLYDLRSQAAKVAKSLRNIGNIQKSSVKKIKSDIILNTEEVFALKKRNFYIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECHHHHHHHHCCCEEHH
DVITRVSPVMAECTKVQKG
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA