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The map label for this gene is tlc [H]

Identifier: 148284886

GI number: 148284886

Start: 1586874

End: 1588373

Strand: Direct

Name: tlc [H]

Synonym: OTBS_1636

Alternate gene names: 148284886

Gene position: 1586874-1588373 (Clockwise)

Preceding gene: 148284884

Following gene: 148284887

Centisome position: 74.6

GC content: 28.8

Gene sequence:

>1500_bases
ATGGCTATCTCCAAGATAAAGCTTTTTTTTTCTAGATTGGTTATTCATTTATGGCCTGTGCACCGCCATGAGCTGCAAAA
ATTTATTCCTACAGCTCTTTTAATGTTTTTCATACTTTTTAATCAAAATATTCTGCGTATTCTTAAAGATAGTATTGTAA
TACCAGAAATAAGTGCTGAAATTACAAGTTTTATAAAAGCATATTGTGTTACACCAACAGCAGCATTGCTTGTAATACTA
TATGCATATATGGTTAATAATTTAAATTATGAAAAAATATACCGGTATTTAACATTAGCATTTTTATCATTTTTTCTTTG
TTTTGCTTTTTGGTTTTATCCCAAAGCAAGTATATTTCACCTAAACATTGAAAAAGTTAACGAGTTAATGTTAATTTATC
CACATTTTAAATGGTATATAGCTCTTGCTGCTAATTGGAGTTACATAATTTTTTATGTATTATCAGAACTATGGCCTAAT
ATATTCTATGCTTTATTATTTTGGCAATTGGTTAATGAAATTACTACTACTGAAGAAGCTAAACGTTTCTATATGCTGTT
TTCATTATTTGGCAATTCTTCTTTAATAGTTGTAGGATTAATTGTAATGCATCTAGCATCTAGCAACTCTATACTTCAGG
GGTATTTTTTAGGAGTATCAAATAACATATTACTTGTACAGTCTTCAATAGCTATAATGGCAGCTAGCTCTATATGCTCA
ATTTTTTTAGTACGATTTATTTATTATAATGCTATACCAAAAACACAGTTACAGCATAAAATGCAGCATGAAAGAGAAGC
GAGACCAAAAATGAATTTACATGAAAGCTTCAAGTATATTATTTCATCAAGATATTTATGGCTTATTTTAATTTGCACTG
CTTCTTTTGGTTTTAGTATGAATTTAGTTGAAGGGATTTGGAAAGCTCAAATTAAAAACTTATACTCTACTACTAATACA
TATGCTGAGTTTAATGGCTCTTGTGTTGTATGGACAGGAGTATTAATAATTTTCTTAACAATTATTGGCAATAGTGTACT
ACGATATCATAGCTGGTTTGTAGTTGCTATTATTACTCCTATTATTATTATTACTACTGGTACAATATTTTTTATTTTTG
TAGTCTTTGATAAAGACATATTATTATGGGTTAATATGCTAAGTTCCGCCCAGCCTATTGCTATAGCTGTAATGGCTGGT
GCAATTCAAAATATTATTGCTAAAGGAGCTAAATACTCAATATGGGATACATCAAAGGAAATGTTATATATTCCGCTTGA
TAAAGAGCTAAAAACTAAAGGAAAAGCTGCTGTTGATATAATTAGTGCTAAAGTAGGAAAATCTTCAGGTGGATTAATTC
AGTCTCTTTTATTTGTTCTATTTCCAACAGCGAGCTATATTTCACTTTCTCCAGCTTTAATGATAATTTTTATTGTAGTA
TGTATAGTATGGATTTTTGCTGTTAAGCAAATTTATTCAGAATATAAAAAAATAGCGTAA

Upstream 100 bases:

>100_bases
ATTACTCTTAATTAACTACAATTCAGTTCTCATTCTCAGAATGCAAAAATATAAGGTATTAGCATTTGTTTGAAATAAGC
TGTAGGAGTAAATCTTAAGT

Downstream 100 bases:

>100_bases
TTTATTGATTATTAAATATAGCAAAAGAGATACATTTGTTAATCGTATGTAAGGTACAAATAAGGAATATTATAAGTTTA
TTGATTAAACAAAAAATTAA

Product: ADP/ATP carrier protein

Products: NA

Alternate protein names: ADP/ATP translocase 5 [H]

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MAISKIKLFFSRLVIHLWPVHRHELQKFIPTALLMFFILFNQNILRILKDSIVIPEISAEITSFIKAYCVTPTAALLVIL
YAYMVNNLNYEKIYRYLTLAFLSFFLCFAFWFYPKASIFHLNIEKVNELMLIYPHFKWYIALAANWSYIIFYVLSELWPN
IFYALLFWQLVNEITTTEEAKRFYMLFSLFGNSSLIVVGLIVMHLASSNSILQGYFLGVSNNILLVQSSIAIMAASSICS
IFLVRFIYYNAIPKTQLQHKMQHEREARPKMNLHESFKYIISSRYLWLILICTASFGFSMNLVEGIWKAQIKNLYSTTNT
YAEFNGSCVVWTGVLIIFLTIIGNSVLRYHSWFVVAIITPIIIITTGTIFFIFVVFDKDILLWVNMLSSAQPIAIAVMAG
AIQNIIAKGAKYSIWDTSKEMLYIPLDKELKTKGKAAVDIISAKVGKSSGGLIQSLLFVLFPTASYISLSPALMIIFIVV
CIVWIFAVKQIYSEYKKIA

Sequences:

>Translated_499_residues
MAISKIKLFFSRLVIHLWPVHRHELQKFIPTALLMFFILFNQNILRILKDSIVIPEISAEITSFIKAYCVTPTAALLVIL
YAYMVNNLNYEKIYRYLTLAFLSFFLCFAFWFYPKASIFHLNIEKVNELMLIYPHFKWYIALAANWSYIIFYVLSELWPN
IFYALLFWQLVNEITTTEEAKRFYMLFSLFGNSSLIVVGLIVMHLASSNSILQGYFLGVSNNILLVQSSIAIMAASSICS
IFLVRFIYYNAIPKTQLQHKMQHEREARPKMNLHESFKYIISSRYLWLILICTASFGFSMNLVEGIWKAQIKNLYSTTNT
YAEFNGSCVVWTGVLIIFLTIIGNSVLRYHSWFVVAIITPIIIITTGTIFFIFVVFDKDILLWVNMLSSAQPIAIAVMAG
AIQNIIAKGAKYSIWDTSKEMLYIPLDKELKTKGKAAVDIISAKVGKSSGGLIQSLLFVLFPTASYISLSPALMIIFIVV
CIVWIFAVKQIYSEYKKIA
>Mature_498_residues
AISKIKLFFSRLVIHLWPVHRHELQKFIPTALLMFFILFNQNILRILKDSIVIPEISAEITSFIKAYCVTPTAALLVILY
AYMVNNLNYEKIYRYLTLAFLSFFLCFAFWFYPKASIFHLNIEKVNELMLIYPHFKWYIALAANWSYIIFYVLSELWPNI
FYALLFWQLVNEITTTEEAKRFYMLFSLFGNSSLIVVGLIVMHLASSNSILQGYFLGVSNNILLVQSSIAIMAASSICSI
FLVRFIYYNAIPKTQLQHKMQHEREARPKMNLHESFKYIISSRYLWLILICTASFGFSMNLVEGIWKAQIKNLYSTTNTY
AEFNGSCVVWTGVLIIFLTIIGNSVLRYHSWFVVAIITPIIIITTGTIFFIFVVFDKDILLWVNMLSSAQPIAIAVMAGA
IQNIIAKGAKYSIWDTSKEMLYIPLDKELKTKGKAAVDIISAKVGKSSGGLIQSLLFVLFPTASYISLSPALMIIFIVVC
IVWIFAVKQIYSEYKKIA

Specific function: Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism [H]

COG id: COG3202

COG function: function code C; ATP/ADP translocase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADP/ATP translocase tlc family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004667 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 57254; Mature: 57123

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISKIKLFFSRLVIHLWPVHRHELQKFIPTALLMFFILFNQNILRILKDSIVIPEISAE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ITSFIKAYCVTPTAALLVILYAYMVNNLNYEKIYRYLTLAFLSFFLCFAFWFYPKASIFH
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LNIEKVNELMLIYPHFKWYIALAANWSYIIFYVLSELWPNIFYALLFWQLVNEITTTEEA
EEHHHHCCEEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRFYMLFSLFGNSSLIVVGLIVMHLASSNSILQGYFLGVSNNILLVQSSIAIMAASSICS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEECHHHHHHHHHHHH
IFLVRFIYYNAIPKTQLQHKMQHEREARPKMNLHESFKYIISSRYLWLILICTASFGFSM
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCH
NLVEGIWKAQIKNLYSTTNTYAEFNGSCVVWTGVLIIFLTIIGNSVLRYHSWFVVAIITP
HHHHHHHHHHHHHHHHCCCCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIIITTGTIFFIFVVFDKDILLWVNMLSSAQPIAIAVMAGAIQNIIAKGAKYSIWDTSKE
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
MLYIPLDKELKTKGKAAVDIISAKVGKSSGGLIQSLLFVLFPTASYISLSPALMIIFIVV
EEEEECCHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CIVWIFAVKQIYSEYKKIA
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AISKIKLFFSRLVIHLWPVHRHELQKFIPTALLMFFILFNQNILRILKDSIVIPEISAE
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ITSFIKAYCVTPTAALLVILYAYMVNNLNYEKIYRYLTLAFLSFFLCFAFWFYPKASIFH
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LNIEKVNELMLIYPHFKWYIALAANWSYIIFYVLSELWPNIFYALLFWQLVNEITTTEEA
EEHHHHCCEEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRFYMLFSLFGNSSLIVVGLIVMHLASSNSILQGYFLGVSNNILLVQSSIAIMAASSICS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEECHHHHHHHHHHHH
IFLVRFIYYNAIPKTQLQHKMQHEREARPKMNLHESFKYIISSRYLWLILICTASFGFSM
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCH
NLVEGIWKAQIKNLYSTTNTYAEFNGSCVVWTGVLIIFLTIIGNSVLRYHSWFVVAIITP
HHHHHHHHHHHHHHHHCCCCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIIITTGTIFFIFVVFDKDILLWVNMLSSAQPIAIAVMAGAIQNIIAKGAKYSIWDTSKE
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
MLYIPLDKELKTKGKAAVDIISAKVGKSSGGLIQSLLFVLFPTASYISLSPALMIIFIVV
EEEEECCHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CIVWIFAVKQIYSEYKKIA
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA