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The map label for this gene is gcp

Identifier: 148284673

GI number: 148284673

Start: 1188990

End: 1190024

Strand: Direct

Name: gcp

Synonym: OTBS_1219

Alternate gene names: 148284673

Gene position: 1188990-1190024 (Clockwise)

Preceding gene: 148284672

Following gene: 148284674

Centisome position: 55.9

GC content: 32.95

Gene sequence:

>1035_bases
GTGAATGTTATTGGTATTGAGTCTAGTTGTGATGATACAGCTATTGCTATAGTTAATAGTAATAGAGAGATAATTGCTAA
TGTAGTAATTTCCCAATATACTGAACATCTTCCTTATAGCGGTGTAGTACCTGAAATTGCAGCTAGGGCTCATCTGAAAA
ATTTGCAATATGCTATGAAAGAAACTTTAAATCAAGCAAAAATTAATTTCACAGATATTGATGTAATTGCAGCTACATCT
GGTCCTGGCTTAATTGGGGGGATAATAGTAGGCTCAGTATTTGGGCAGGCAATTGCATGCGCATTAGGCAAAGATTTCAT
TGCAGTAAATCATTTAGAAGGGCATATACTAGCAGTGCGACTAAATGAGAACATTAGTTTTCCTTATTTGGTATTGCTTG
TTTCTGGAGGGCATTGCCAATTTATTGCAGTATTAGGAGTTGGTAAATATAAGATTTTAGGACAAACTATTGATGATGCT
GTTGGTGAAGCATTTGATAAAACAGCTAGACTATTAAAACTTGGATATCCTGGAGGACCAATCATTGAAAAATTAGCTAG
TAAAGGTGATCCTCACAAATATTCTTTACCATTGTCAATGACAAAGAAATCTGGCTGTGATCTATCATTTTCTGGATTAA
AAACAGCAGTTAAGCAATTAATATTTAGTATAGAATCTTTATCTGAAAAAGTAATTTGTGATATATGCGCTTCGTTTCAA
TACACTGTAGTTCAGATTCTACTGTGCCGTAGTATTAATGCTATTAAATTGTTTGAAAGTTATTGTAGCAATAATTTTAA
AATTAATAGGAAAAATTATTTTGTTATATCAGGAGGAGTAGCAGCTAATCAATATCTGAGACAAGAAATATTTAATTTAG
CTAATACATATGGCTACTGCGGTGTTGCTCCACCTAGCAATTTGTGTACTGATAATGCAGCAATGATAGCTTGGGCAGGA
ATAGAAAGATTAAACGCTAATTTATTTAGTAGTAATTTTGTTCCAAGAGCTAAATGGAGTGTTGAAGAACTTTAA

Upstream 100 bases:

>100_bases
CTATCTTGGAATCTGTAAAATATGAAGAAATAATTGAAAAGCTAACTGAAATCTTGAAAAATAGAAATACTGTATAATCA
ACATACATAAGAAGTTTATT

Downstream 100 bases:

>100_bases
TTTAATAGCCCCATGAATGTAAAGAACATAAGATATTTTACTTCTAATTTAGCTAAGTCTGCACAGATAGCAAATGAATT
ACAACAAAAATATAATATTC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMKETLNQAKINFTDIDVIAATS
GPGLIGGIIVGSVFGQAIACALGKDFIAVNHLEGHILAVRLNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDA
VGEAFDKTARLLKLGYPGGPIIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLANTYGYCGVAPPSNLCTDNAAMIAWAG
IERLNANLFSSNFVPRAKWSVEEL

Sequences:

>Translated_344_residues
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMKETLNQAKINFTDIDVIAATS
GPGLIGGIIVGSVFGQAIACALGKDFIAVNHLEGHILAVRLNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDA
VGEAFDKTARLLKLGYPGGPIIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLANTYGYCGVAPPSNLCTDNAAMIAWAG
IERLNANLFSSNFVPRAKWSVEEL
>Mature_344_residues
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMKETLNQAKINFTDIDVIAATS
GPGLIGGIIVGSVFGQAIACALGKDFIAVNHLEGHILAVRLNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDA
VGEAFDKTARLLKLGYPGGPIIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLANTYGYCGVAPPSNLCTDNAAMIAWAG
IERLNANLFSSNFVPRAKWSVEEL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=341, Percent_Identity=36.950146627566, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI8923380, Length=326, Percent_Identity=31.9018404907975, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1789445, Length=347, Percent_Identity=40.9221902017291, Blast_Score=265, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17557464, Length=350, Percent_Identity=32.2857142857143, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71995670, Length=327, Percent_Identity=32.1100917431193, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=374, Percent_Identity=31.5508021390374, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6322891, Length=321, Percent_Identity=32.398753894081, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=36.8421052631579, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI21357207, Length=332, Percent_Identity=30.1204819277108, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_ORITB (A5CE49)

Other databases:

- EMBL:   AM494475
- RefSeq:   YP_001248763.1
- STRING:   A5CE49
- MEROPS:   M22.001
- GeneID:   5219809
- GenomeReviews:   AM494475_GR
- KEGG:   ots:OTBS_1219
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   OTSU357244:OTBS_1219-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37240; Mature: 37240

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMK
CCEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ETLNQAKINFTDIDVIAATSGPGLIGGIIVGSVFGQAIACALGKDFIAVNHLEGHILAVR
HHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEE
LNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDAVGEAFDKTARLLKLGYPGGP
ECCCCCCCEEEEEEECCCEEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHEEECCCCCH
IIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
HHHHHHCCCCCCEEECCEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLANTYGYC
HHHHHHHHHCCCCHHHHHHHHHCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHCCCC
GVAPPSNLCTDNAAMIAWAGIERLNANLFSSNFVPRAKWSVEEL
CCCCCCCCCCCCCCEEEEHHHHHHCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMK
CCEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ETLNQAKINFTDIDVIAATSGPGLIGGIIVGSVFGQAIACALGKDFIAVNHLEGHILAVR
HHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEE
LNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDAVGEAFDKTARLLKLGYPGGP
ECCCCCCCEEEEEEECCCEEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHEEECCCCCH
IIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
HHHHHHCCCCCCEEECCEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLANTYGYC
HHHHHHHHHCCCCHHHHHHHHHCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHCCCC
GVAPPSNLCTDNAAMIAWAGIERLNANLFSSNFVPRAKWSVEEL
CCCCCCCCCCCCCCEEEEHHHHHHCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA