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The map label for this gene is holA

Identifier: 148284276

GI number: 148284276

Start: 446743

End: 447762

Strand: Direct

Name: holA

Synonym: OTBS_0469

Alternate gene names: NA

Gene position: 446743-447762 (Clockwise)

Preceding gene: 148284275

Following gene: 148284277

Centisome position: 21.0

GC content: 28.04

Gene sequence:

>1020_bases
GTGAAGTTCACGTCTTATAATATTGCTGCATTATGGTCTTATATTAAAAAGGGGGATATTAGAGCAATAGCAGTTTACGG
TAATGATCATGGATTAATTGATTACCGGTGTCAGGAAATTACTAAGTTGTTCAATGCTAATCTTAGAATATATGATTATA
GAGAGCTTACTGAAGCTGATTTTATTTTTATATTAAACTCTAATAACTTATTTTCTCAACGTGAAATAGTAAAAATATAT
AATACTCCTGGCAATATTAATGCAGCATTAAAAAAAGCTTTAACTTTCAATAATCAGAATTTTTTAATAGTGTTAGGCAA
TGAGTTCTCAGCTTCTTCTACCACTAGACAATGGTTTGAAACTCAAAAATATCTTGCAGCACTAGGATGTTATACAGAAA
ATAGCCAAGATATAAAGAAATTATTATCACAAATTGTGAATAAAGCAGGCAAAAATATTACTGCAGAAGCGGCAGTATAT
TTTTCTAATACTGCTTATGGAGATAAGTACTGTTATATTAATGAAATTAATAAGCTTATACTGTATTGTCATGATTGCGA
TACTATTAGTAAGAAGGAAGTAAATAAATGCATTAGCACAGAAATACTTGGAACATCTGATCTTATGTGTATATATTTCG
CCAAGGGAATAGCAATGAATTTTTTTAAAGAAGTAGAAAAGATAAGAAATAATAACATACCAGATGTTTGGATATTACGA
GCACTAATTAGATACTATATTAACCTGTATATTGTTTTAATGAAAAGAGAACATGGAGTTAGTATTGAACAAGCCATTAA
ATCAATTCAACCTTCCATATTTTTTAAATATGTTCAAGATTTTCAACTAATAGCACAAACTAAGACATTAAATAACGTAT
TGCATACATTGAATGAATTATATATGGCGGAATTATCAGTTAAGACAACACATCATCATATCAATAACATTATTGAAGTA
GTTTTTTTGAAAATAACCCATAAGTTGCGTTTGAGTTTTGAATTTACTGTATTAGTATAA

Upstream 100 bases:

>100_bases
CAGGTTAAAAAGCATATTGGCGATAAAGAAGTAAGAAAATGTATTTTTGTTCCAAATAAATTAATTAATATAATTATATG
ATAATATAGGATTATTACTA

Downstream 100 bases:

>100_bases
TTTGTTGCAAAAAAAATATACATAATAGTTGATTATTAGTTAATAATTTGATATCTAATGATTCAGGCGGTTGTGGCGGA
ATCGGTAGACGCGCAGCATT

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKFTSYNIAALWSYIKKGDIRAIAVYGNDHGLIDYRCQEITKLFNANLRIYDYRELTEADFIFILNSNNLFSQREIVKIY
NTPGNINAALKKALTFNNQNFLIVLGNEFSASSTTRQWFETQKYLAALGCYTENSQDIKKLLSQIVNKAGKNITAEAAVY
FSNTAYGDKYCYINEINKLILYCHDCDTISKKEVNKCISTEILGTSDLMCIYFAKGIAMNFFKEVEKIRNNNIPDVWILR
ALIRYYINLYIVLMKREHGVSIEQAIKSIQPSIFFKYVQDFQLIAQTKTLNNVLHTLNELYMAELSVKTTHHHINNIIEV
VFLKITHKLRLSFEFTVLV

Sequences:

>Translated_339_residues
MKFTSYNIAALWSYIKKGDIRAIAVYGNDHGLIDYRCQEITKLFNANLRIYDYRELTEADFIFILNSNNLFSQREIVKIY
NTPGNINAALKKALTFNNQNFLIVLGNEFSASSTTRQWFETQKYLAALGCYTENSQDIKKLLSQIVNKAGKNITAEAAVY
FSNTAYGDKYCYINEINKLILYCHDCDTISKKEVNKCISTEILGTSDLMCIYFAKGIAMNFFKEVEKIRNNNIPDVWILR
ALIRYYINLYIVLMKREHGVSIEQAIKSIQPSIFFKYVQDFQLIAQTKTLNNVLHTLNELYMAELSVKTTHHHINNIIEV
VFLKITHKLRLSFEFTVLV
>Mature_339_residues
MKFTSYNIAALWSYIKKGDIRAIAVYGNDHGLIDYRCQEITKLFNANLRIYDYRELTEADFIFILNSNNLFSQREIVKIY
NTPGNINAALKKALTFNNQNFLIVLGNEFSASSTTRQWFETQKYLAALGCYTENSQDIKKLLSQIVNKAGKNITAEAAVY
FSNTAYGDKYCYINEINKLILYCHDCDTISKKEVNKCISTEILGTSDLMCIYFAKGIAMNFFKEVEKIRNNNIPDVWILR
ALIRYYINLYIVLMKREHGVSIEQAIKSIQPSIFFKYVQDFQLIAQTKTLNNVLHTLNELYMAELSVKTTHHHINNIIEV
VFLKITHKLRLSFEFTVLV

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921 [H]

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 39277; Mature: 39277

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTSYNIAALWSYIKKGDIRAIAVYGNDHGLIDYRCQEITKLFNANLRIYDYRELTEAD
CCCCCCHHHHHHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHHHCCCCEEEEHHHCCCCC
FIFILNSNNLFSQREIVKIYNTPGNINAALKKALTFNNQNFLIVLGNEFSASSTTRQWFE
EEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHEECCCEEEEEECCCCCCCHHHHHHHH
TQKYLAALGCYTENSQDIKKLLSQIVNKAGKNITAEAAVYFSNTAYGDKYCYINEINKLI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEHCCCCEEE
LYCHDCDTISKKEVNKCISTEILGTSDLMCIYFAKGIAMNFFKEVEKIRNNNIPDVWILR
EEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALIRYYINLYIVLMKREHGVSIEQAIKSIQPSIFFKYVQDFQLIAQTKTLNNVLHTLNEL
HHHHHHHHHEEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMAELSVKTTHHHINNIIEVVFLKITHKLRLSFEFTVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEC
>Mature Secondary Structure
MKFTSYNIAALWSYIKKGDIRAIAVYGNDHGLIDYRCQEITKLFNANLRIYDYRELTEAD
CCCCCCHHHHHHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHHHCCCCEEEEHHHCCCCC
FIFILNSNNLFSQREIVKIYNTPGNINAALKKALTFNNQNFLIVLGNEFSASSTTRQWFE
EEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHEECCCEEEEEECCCCCCCHHHHHHHH
TQKYLAALGCYTENSQDIKKLLSQIVNKAGKNITAEAAVYFSNTAYGDKYCYINEINKLI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEHCCCCEEE
LYCHDCDTISKKEVNKCISTEILGTSDLMCIYFAKGIAMNFFKEVEKIRNNNIPDVWILR
EEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALIRYYINLYIVLMKREHGVSIEQAIKSIQPSIFFKYVQDFQLIAQTKTLNNVLHTLNEL
HHHHHHHHHEEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMAELSVKTTHHHINNIIEVVFLKITHKLRLSFEFTVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]