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The map label for this gene is ctaC [H]

Identifier: 148261158

GI number: 148261158

Start: 2391578

End: 2392528

Strand: Reverse

Name: ctaC [H]

Synonym: Acry_2167

Alternate gene names: 148261158

Gene position: 2392528-2391578 (Counterclockwise)

Preceding gene: 148261159

Following gene: 148261157

Centisome position: 70.59

GC content: 63.83

Gene sequence:

>951_bases
ATGAAACGATCCAACAAATATCTGTTCCTGGGCCTGGTCGGCTTCGCGGTTCTCGCCGCGGGCGCGCCGATGGCGCTTGC
CGCCGCGAAGAATGCCGTCGGGTTTCCGGTGCATGCGCCGACGCCGTGGGAATGGTGGTTCCAGCCCGCCGCCAGCCCGA
TCCAGAAGAGCATCGACTGGCTCATGCAGTTCGTGCTCTGGATCATGGCGGGCGTGGTCGGGCTGGTGGGCCTGCTGCTG
GCCATCGTGATCATCCGCTTCCGCGCCTCGAAGCACCCGGTGGCGACGACCACGACGCACAACACGCTGATCGAGGTGAT
CTGGACGGTGGTGCCGGCGTTGCTGCTGGTCGTGATCTTCGTGCCGTCGCTGAACCTGATCTACGAACAGTCGAACTACA
CGCACCGCTACATGACCGTGAAGGTCACCGGGCACCAGTGGTATTGGGAATACGACTATCCCGCCGCCAAGGGGGTCGAT
TTCACCTCGTACCCGATCCCCGACAACCAGATCAAACCCGGGCAGATCGCGCGGCTTTCGGCGGATCACCCGCTGGTGCT
GCCGGCGAACGAGAAGATCGTCTTCAAGATCACCAGCGCCGACGTGCTGCACTCGTTCTTCATTCCCTCGCTCGGCGTGC
AGCGCTACGCCATTCCCGGCCAGTACTGGCACCAGTGGACCAAGATCGACGCGCCGGGCATCTATTACGGCGAGTGCAAC
CAGATCTGCGGCATGAACCACGACAACATGCCGATCGAGATCGTCGCGCTTCCGCTGAAGCAGTTCAAGGCGTGGCTGGC
CGAGGCGAAGGCCGACGCCGCGCAGGGCAATGTGCCGCCCGTGCGCAAATACGAGGTGCTGGCCATGGCCGATGCGGCGA
AGAAGGCCGCATCGCGCGCGCAGGGGCACATCGCCCTGGCCAGCGCAACCACCGATGAAACGACGCGTTAA

Upstream 100 bases:

>100_bases
GGGCGTAATCGGCCCCGGCTGCGCTGTGACGTATTTTTATTTCAACTGACTTCGACGGCCGCGCCGAACGCGGTCCGAGT
ACACGGAACTGGCGGAGCTG

Downstream 100 bases:

>100_bases
TCTGTAGTCGGCGATCATCAGGAGCATATGACAATGTCCGCGACCGCACTGCACGATGCCCATGGCGAACATGCCCACCA
CCAGCCGGGATTCTTCCGGC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKRSNKYLFLGLVGFAVLAAGAPMALAAAKNAVGFPVHAPTPWEWWFQPAASPIQKSIDWLMQFVLWIMAGVVGLVGLLL
AIVIIRFRASKHPVATTTTHNTLIEVIWTVVPALLLVVIFVPSLNLIYEQSNYTHRYMTVKVTGHQWYWEYDYPAAKGVD
FTSYPIPDNQIKPGQIARLSADHPLVLPANEKIVFKITSADVLHSFFIPSLGVQRYAIPGQYWHQWTKIDAPGIYYGECN
QICGMNHDNMPIEIVALPLKQFKAWLAEAKADAAQGNVPPVRKYEVLAMADAAKKAASRAQGHIALASATTDETTR

Sequences:

>Translated_316_residues
MKRSNKYLFLGLVGFAVLAAGAPMALAAAKNAVGFPVHAPTPWEWWFQPAASPIQKSIDWLMQFVLWIMAGVVGLVGLLL
AIVIIRFRASKHPVATTTTHNTLIEVIWTVVPALLLVVIFVPSLNLIYEQSNYTHRYMTVKVTGHQWYWEYDYPAAKGVD
FTSYPIPDNQIKPGQIARLSADHPLVLPANEKIVFKITSADVLHSFFIPSLGVQRYAIPGQYWHQWTKIDAPGIYYGECN
QICGMNHDNMPIEIVALPLKQFKAWLAEAKADAAQGNVPPVRKYEVLAMADAAKKAASRAQGHIALASATTDETTR
>Mature_316_residues
MKRSNKYLFLGLVGFAVLAAGAPMALAAAKNAVGFPVHAPTPWEWWFQPAASPIQKSIDWLMQFVLWIMAGVVGLVGLLL
AIVIIRFRASKHPVATTTTHNTLIEVIWTVVPALLLVVIFVPSLNLIYEQSNYTHRYMTVKVTGHQWYWEYDYPAAKGVD
FTSYPIPDNQIKPGQIARLSADHPLVLPANEKIVFKITSADVLHSFFIPSLGVQRYAIPGQYWHQWTKIDAPGIYYGECN
QICGMNHDNMPIEIVALPLKQFKAWLAEAKADAAQGNVPPVRKYEVLAMADAAKKAASRAQGHIALASATTDETTR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=160, Percent_Identity=42.5, Blast_Score=146, Evalue=2e-35,
Organism=Escherichia coli, GI1786635, Length=286, Percent_Identity=25.8741258741259, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6226540, Length=236, Percent_Identity=38.5593220338983, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 35049; Mature: 35049

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSNKYLFLGLVGFAVLAAGAPMALAAAKNAVGFPVHAPTPWEWWFQPAASPIQKSIDW
CCCCCCEEEEHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHH
LMQFVLWIMAGVVGLVGLLLAIVIIRFRASKHPVATTTTHNTLIEVIWTVVPALLLVVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
VPSLNLIYEQSNYTHRYMTVKVTGHQWYWEYDYPAAKGVDFTSYPIPDNQIKPGQIARLS
HCCCEEEEECCCCEEEEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEC
ADHPLVLPANEKIVFKITSADVLHSFFIPSLGVQRYAIPGQYWHQWTKIDAPGIYYGECN
CCCCEEEECCCEEEEEECCHHHHHHHHCCCCCCEEEECCHHHHHHHHEECCCEEEECCCH
QICGMNHDNMPIEIVALPLKQFKAWLAEAKADAAQGNVPPVRKYEVLAMADAAKKAASRA
HHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHC
QGHIALASATTDETTR
CCCEEEEECCCCCCCC
>Mature Secondary Structure
MKRSNKYLFLGLVGFAVLAAGAPMALAAAKNAVGFPVHAPTPWEWWFQPAASPIQKSIDW
CCCCCCEEEEHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHH
LMQFVLWIMAGVVGLVGLLLAIVIIRFRASKHPVATTTTHNTLIEVIWTVVPALLLVVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
VPSLNLIYEQSNYTHRYMTVKVTGHQWYWEYDYPAAKGVDFTSYPIPDNQIKPGQIARLS
HCCCEEEEECCCCEEEEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEC
ADHPLVLPANEKIVFKITSADVLHSFFIPSLGVQRYAIPGQYWHQWTKIDAPGIYYGECN
CCCCEEEECCCEEEEEECCHHHHHHHHCCCCCCEEEECCHHHHHHHHEECCCEEEECCCH
QICGMNHDNMPIEIVALPLKQFKAWLAEAKADAAQGNVPPVRKYEVLAMADAAKKAASRA
HHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHC
QGHIALASATTDETTR
CCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA