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The map label for this gene is pntB [H]

Identifier: 148261146

GI number: 148261146

Start: 2379081

End: 2380499

Strand: Reverse

Name: pntB [H]

Synonym: Acry_2155

Alternate gene names: 148261146

Gene position: 2380499-2379081 (Counterclockwise)

Preceding gene: 148261147

Following gene: 148261145

Centisome position: 70.24

GC content: 67.09

Gene sequence:

>1419_bases
ATGAATTACGCATCCGATCCGGGGATCACGCTCGCCTATCTGGTGGCGGCCGTCCTGTTCATCCTGGCCCTGCGCGGGCT
TTCGCATCCCGAGACCGCGCGGCGCGGCAACCTGCTCGGCATGGCCGGCATGGCGATCGCCGCGCTGGCGACGCTGGCGC
ATCCGGCGATGCTGCTCTCGGGCGTGGGGCTCATCGTGCTCGGCGTCGTCATCGGCGGCGCGATCGGCGCGGTGGTGGCG
CGGCGGGTCAACATGACCGCGCTGCCGCAGCTCGTCGCCGCGTTCCACTCGCTGGTGGGGCTTGCCGCGGTGTTCGTCGC
CGCCTCGGCGCTGAACGCGCCGCAGAGCTTCGGCATCGGCACGCCGGGGCACCTGCATCTCGAAAGCCTGATCGAGATGT
CGCTCGGCCTGTCGATCGGCGCCATCACCTTCACCGGCGCGGTCATCGCCTTCGCCAAGCTGCAGGCGCTGATGAGCGGC
GCGCCGATCAACTTCCCCGGCCAGCACAAGCTCAATCTCGGCCTCGGCATCCTGCTCGTGGTGCTGATCATCGCCTTCGT
CGCCTCGGGCGGCTCGCAGGTGCTGTTCTGGATCATCGCGGCCCTCGCGCTCGCGCTTGGCGTGCTGCTGATCATCCCGA
TCGGCGGTGCGGACATGCCGGTGGTGATCTCGATGCTGAACTCCTATTCCGGCTGGGCGGCGGCGGGCATCGGCTTCACC
ATCAGCAACATCGCGCTGATCGTGACCGGCGCGCTGGTCGGCTCGTCGGGTGCGATTCTCTCCTACATCATGTGCAAGGG
GATGAACCGCTCGATCCTCAACGTGCTGCTCGGCGGCTTCGGCACCGATGCCGCCGCCGCGGCCGGCCCCGCGGGGGCCG
CCGGCGACAAGGCGGTGAAGATCGGCTCGGCCGAGGATGCGAGCTTCATCATGAGCAACGCCTCGAAGGTGATCATCGTG
CCGGGCTACGGCATGGCGGTGGCCCAGGCGCAGCACGCGGTGCGCGAGATGTCCGACCTGCTGAAGGAGGCGGGCGTCGA
GGTGAAATACGCGATCCATCCGGTCGCCGGCCGCATGCCGGGGCACATGAACGTGCTGCTCGCCGAGGCGCAGGTGCCGT
ATGACGAGGTGTTCGAACTCGAGGAGATCAACAACGAGTTCTCGACCGCCGACGTGGTCTACGTGATCGGCGCGAACGAC
GTGACCAACCCGGCGGCGAAGACCAATTCGTCGAGCCCGATCTACGGCATGCCGATCCTCGAGGTCGACAAGGCGAAGAC
GGTGCTGTTCGTCAAGCGCTCGATGGCCTCGGGCTATGCCGGCGTGGAGAACGAGCTGTTCTTCCGCGACAACACGATGA
TGCTGTTCGGCGACGCGAAGAAGATGACCGAGGAGATCGTGCAGTCGCTCGGCAAGTAA

Upstream 100 bases:

>100_bases
GCGGTGCTGCTGGCCAGCGTGAACATCGTGGGCGGCTTCCTCGTGACCCAGCGCATGCTGGCCATGTTCAAGAAAAAAGC
GAAGTAAGGGCGGCGCGACA

Downstream 100 bases:

>100_bases
GCCGGGCGAACGCGGGACGATCCGGCGGCGGGGGCCACTGGCTCCGCCGCTTTCGTTTGGGGACGCGCTTGCCAGCGGCG
GGAAATTCGGCCATAGGCGG

Product: NAD(P)(+) transhydrogenase

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MNYASDPGITLAYLVAAVLFILALRGLSHPETARRGNLLGMAGMAIAALATLAHPAMLLSGVGLIVLGVVIGGAIGAVVA
RRVNMTALPQLVAAFHSLVGLAAVFVAASALNAPQSFGIGTPGHLHLESLIEMSLGLSIGAITFTGAVIAFAKLQALMSG
APINFPGQHKLNLGLGILLVVLIIAFVASGGSQVLFWIIAALALALGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFT
ISNIALIVTGALVGSSGAILSYIMCKGMNRSILNVLLGGFGTDAAAAAGPAGAAGDKAVKIGSAEDASFIMSNASKVIIV
PGYGMAVAQAQHAVREMSDLLKEAGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEEINNEFSTADVVYVIGAND
VTNPAAKTNSSSPIYGMPILEVDKAKTVLFVKRSMASGYAGVENELFFRDNTMMLFGDAKKMTEEIVQSLGK

Sequences:

>Translated_472_residues
MNYASDPGITLAYLVAAVLFILALRGLSHPETARRGNLLGMAGMAIAALATLAHPAMLLSGVGLIVLGVVIGGAIGAVVA
RRVNMTALPQLVAAFHSLVGLAAVFVAASALNAPQSFGIGTPGHLHLESLIEMSLGLSIGAITFTGAVIAFAKLQALMSG
APINFPGQHKLNLGLGILLVVLIIAFVASGGSQVLFWIIAALALALGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFT
ISNIALIVTGALVGSSGAILSYIMCKGMNRSILNVLLGGFGTDAAAAAGPAGAAGDKAVKIGSAEDASFIMSNASKVIIV
PGYGMAVAQAQHAVREMSDLLKEAGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEEINNEFSTADVVYVIGAND
VTNPAAKTNSSSPIYGMPILEVDKAKTVLFVKRSMASGYAGVENELFFRDNTMMLFGDAKKMTEEIVQSLGK
>Mature_472_residues
MNYASDPGITLAYLVAAVLFILALRGLSHPETARRGNLLGMAGMAIAALATLAHPAMLLSGVGLIVLGVVIGGAIGAVVA
RRVNMTALPQLVAAFHSLVGLAAVFVAASALNAPQSFGIGTPGHLHLESLIEMSLGLSIGAITFTGAVIAFAKLQALMSG
APINFPGQHKLNLGLGILLVVLIIAFVASGGSQVLFWIIAALALALGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFT
ISNIALIVTGALVGSSGAILSYIMCKGMNRSILNVLLGGFGTDAAAAAGPAGAAGDKAVKIGSAEDASFIMSNASKVIIV
PGYGMAVAQAQHAVREMSDLLKEAGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEEINNEFSTADVVYVIGAND
VTNPAAKTNSSSPIYGMPILEVDKAKTVLFVKRSMASGYAGVENELFFRDNTMMLFGDAKKMTEEIVQSLGK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=462, Percent_Identity=46.7532467532467, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI122939153, Length=462, Percent_Identity=46.7532467532467, Blast_Score=370, Evalue=1e-102,
Organism=Escherichia coli, GI1787886, Length=465, Percent_Identity=53.9784946236559, Blast_Score=464, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17550456, Length=474, Percent_Identity=45.1476793248945, Blast_Score=360, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 48469; Mature: 48469

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYASDPGITLAYLVAAVLFILALRGLSHPETARRGNLLGMAGMAIAALATLAHPAMLLS
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GVGLIVLGVVIGGAIGAVVARRVNMTALPQLVAAFHSLVGLAAVFVAASALNAPQSFGIG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
TPGHLHLESLIEMSLGLSIGAITFTGAVIAFAKLQALMSGAPINFPGQHKLNLGLGILLV
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHH
VLIIAFVASGGSQVLFWIIAALALALGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCCCHHCCCHH
ISNIALIVTGALVGSSGAILSYIMCKGMNRSILNVLLGGFGTDAAAAAGPAGAAGDKAVK
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCEEE
IGSAEDASFIMSNASKVIIVPGYGMAVAQAQHAVREMSDLLKEAGVEVKYAIHPVAGRMP
ECCCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
GHMNVLLAEAQVPYDEVFELEEINNEFSTADVVYVIGANDVTNPAAKTNSSSPIYGMPIL
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCCE
EVDKAKTVLFVKRSMASGYAGVENELFFRDNTMMLFGDAKKMTEEIVQSLGK
EECCCCEEEEEHHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYASDPGITLAYLVAAVLFILALRGLSHPETARRGNLLGMAGMAIAALATLAHPAMLLS
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GVGLIVLGVVIGGAIGAVVARRVNMTALPQLVAAFHSLVGLAAVFVAASALNAPQSFGIG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
TPGHLHLESLIEMSLGLSIGAITFTGAVIAFAKLQALMSGAPINFPGQHKLNLGLGILLV
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHH
VLIIAFVASGGSQVLFWIIAALALALGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCCCHHCCCHH
ISNIALIVTGALVGSSGAILSYIMCKGMNRSILNVLLGGFGTDAAAAAGPAGAAGDKAVK
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCEEE
IGSAEDASFIMSNASKVIIVPGYGMAVAQAQHAVREMSDLLKEAGVEVKYAIHPVAGRMP
ECCCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
GHMNVLLAEAQVPYDEVFELEEINNEFSTADVVYVIGANDVTNPAAKTNSSSPIYGMPIL
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCCE
EVDKAKTVLFVKRSMASGYAGVENELFFRDNTMMLFGDAKKMTEEIVQSLGK
EECCCCEEEEEHHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]