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The map label for this gene is ffh [H]

Identifier: 148261145

GI number: 148261145

Start: 2377538

End: 2378911

Strand: Reverse

Name: ffh [H]

Synonym: Acry_2154

Alternate gene names: 148261145

Gene position: 2378911-2377538 (Counterclockwise)

Preceding gene: 148261146

Following gene: 148261144

Centisome position: 70.19

GC content: 68.92

Gene sequence:

>1374_bases
ATGTTTGACGCCCTGTCGGGCAAGCTCGGGGATGTTTTCGACCGGTTGCGCCGGCGCGGCGCGCTGTCCGAAAGCGATGT
GATCGAGGCGATGCGGGATATCCGCCTCGCGCTGCTCGAAGCCGACGTCGCTTTGCCGGTGGTGCGGGATTTCATCGCCA
AGGTGCGGTTGCAGGCGGTGGGCGCGGAGGTGCTGCGGGCGGTCTCGCCGGGGCAGCAGGTCGTCAAGATCGTCAACGAC
GCGCTGGTCGACGCCCTCGGCGGCGAGGGGGCGGTGCCGCTCAACCTCAACGCGGCATCACCCATTCCGTTCCTGATGGT
CGGGTTGCAGGGCTCGGGCAAGACCACGACCTCGGGCAAGATCGCGCTCCTGCTCAAGGAGAAGCAGCGCAAGAAGGTGC
TGCTGGCGAGCCTCGATACCCAGCGCCCGGCCGCACAGCTCCAGCTCGCGCAGCTGGCCGAGCGCGCCGGGGTGGCGAGC
CTGCCGATCGTGCCGGGGGAGACGCCGGTGCAGATCGCGCGGCGGGCGATGGAGACCGGGCGGCGCGAGGTGTTCGACGT
CGTCATCCTCGACACCGCCGGACGGCTCGCGATCGACCAGGCGCTGATGGACGAGGTCAAGGCGATCCGCGACGTGACCG
CGCCGGCGGAGACGCTGCTGGTGGTCGACGCGATGACCGGCCAGGACGCGCTCGCCACGGCGACGGCGTTCAACGAGGCG
GTGAGCATCACCGGCATCGTCATGACGCGGCTCGATGGCGACGCGCGGGGCGGCGCCGCGCTGTCGATGCGGGCGGTGAC
GGGCGCGCCGATCAAGCTGATGGGCATGGGCGAGAAGCTCGATGCGCTGGAGCCGTTCCATCCCGAGCGCATCGCCGGGC
GCATCCTCGGCATGGGCGACATTGTCAGCCTGGTCGAGAAGGCGGCGGAGAATGTCGACCAGCAGAAGGCCGAACAGCTC
GCCAAGAAGATGGCGCGCGGCAAGTTCGACCTCGAGGATTATGCCGAGCAGCTCAAGCAGATCACCAAGATGGGCTCGCT
GTCGGGCATCATGGGCATGCTGCCCGGCGTGGGCAAGATCAAGCAGCAGCTCGCCGAGGCGGATCTCGACACCTCGATCC
TGAAGCGGCAGGCGGCGATCATCTCCTCGATGACCAAGGCCGAGCGGGCCAATCCGGACATCATGAAGGCGAGCCGGAAG
AAGCGCGTGGCGGCGGGCTCGGGCACCTCGGTGCAGGAGGTCAACCGGCTGCTCAAGCAGTTCGAGCAGATGAAGGACAT
GATGAAGCGGGCGCAGAAGCTGGGCCAGAAGGGCCTCGCGCGCGGCGGGCTGGCCGCGCTGCTGCCGCAGGGAGGCGGGC
GCCGCCCGTTCTGA

Upstream 100 bases:

>100_bases
TGCCAGCGGCGGGAAATTCGGCCATAGGCGGAGCGGAATAGAGCCGTCGCGCTGCGAGTTTCGCACCGCGGCGCGTTTTT
CGTTGATGGAGCGGGTTGCG

Downstream 100 bases:

>100_bases
GATCGCGGGTTTTTGCCCGGACTGAAAACCGCGGGTTTCGGCCCGGAGTGAAATAACGGGCTTCGGCCCGGAGCGAAATA
ACGGGCTTTGGCCCGGACTG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MFDALSGKLGDVFDRLRRRGALSESDVIEAMRDIRLALLEADVALPVVRDFIAKVRLQAVGAEVLRAVSPGQQVVKIVND
ALVDALGGEGAVPLNLNAASPIPFLMVGLQGSGKTTTSGKIALLLKEKQRKKVLLASLDTQRPAAQLQLAQLAERAGVAS
LPIVPGETPVQIARRAMETGRREVFDVVILDTAGRLAIDQALMDEVKAIRDVTAPAETLLVVDAMTGQDALATATAFNEA
VSITGIVMTRLDGDARGGAALSMRAVTGAPIKLMGMGEKLDALEPFHPERIAGRILGMGDIVSLVEKAAENVDQQKAEQL
AKKMARGKFDLEDYAEQLKQITKMGSLSGIMGMLPGVGKIKQQLAEADLDTSILKRQAAIISSMTKAERANPDIMKASRK
KRVAAGSGTSVQEVNRLLKQFEQMKDMMKRAQKLGQKGLARGGLAALLPQGGGRRPF

Sequences:

>Translated_457_residues
MFDALSGKLGDVFDRLRRRGALSESDVIEAMRDIRLALLEADVALPVVRDFIAKVRLQAVGAEVLRAVSPGQQVVKIVND
ALVDALGGEGAVPLNLNAASPIPFLMVGLQGSGKTTTSGKIALLLKEKQRKKVLLASLDTQRPAAQLQLAQLAERAGVAS
LPIVPGETPVQIARRAMETGRREVFDVVILDTAGRLAIDQALMDEVKAIRDVTAPAETLLVVDAMTGQDALATATAFNEA
VSITGIVMTRLDGDARGGAALSMRAVTGAPIKLMGMGEKLDALEPFHPERIAGRILGMGDIVSLVEKAAENVDQQKAEQL
AKKMARGKFDLEDYAEQLKQITKMGSLSGIMGMLPGVGKIKQQLAEADLDTSILKRQAAIISSMTKAERANPDIMKASRK
KRVAAGSGTSVQEVNRLLKQFEQMKDMMKRAQKLGQKGLARGGLAALLPQGGGRRPF
>Mature_457_residues
MFDALSGKLGDVFDRLRRRGALSESDVIEAMRDIRLALLEADVALPVVRDFIAKVRLQAVGAEVLRAVSPGQQVVKIVND
ALVDALGGEGAVPLNLNAASPIPFLMVGLQGSGKTTTSGKIALLLKEKQRKKVLLASLDTQRPAAQLQLAQLAERAGVAS
LPIVPGETPVQIARRAMETGRREVFDVVILDTAGRLAIDQALMDEVKAIRDVTAPAETLLVVDAMTGQDALATATAFNEA
VSITGIVMTRLDGDARGGAALSMRAVTGAPIKLMGMGEKLDALEPFHPERIAGRILGMGDIVSLVEKAAENVDQQKAEQL
AKKMARGKFDLEDYAEQLKQITKMGSLSGIMGMLPGVGKIKQQLAEADLDTSILKRQAAIISSMTKAERANPDIMKASRK
KRVAAGSGTSVQEVNRLLKQFEQMKDMMKRAQKLGQKGLARGGLAALLPQGGGRRPF

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=430, Percent_Identity=34.8837209302326, Blast_Score=215, Evalue=8e-56,
Organism=Homo sapiens, GI226371618, Length=345, Percent_Identity=37.3913043478261, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI89061728, Length=160, Percent_Identity=37.5, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI23308697, Length=202, Percent_Identity=33.1683168316832, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI295424842, Length=202, Percent_Identity=33.1683168316832, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1788963, Length=426, Percent_Identity=53.2863849765258, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1789874, Length=200, Percent_Identity=42, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17539958, Length=451, Percent_Identity=31.9290465631929, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI193206261, Length=201, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6325345, Length=429, Percent_Identity=34.032634032634, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6320498, Length=214, Percent_Identity=29.4392523364486, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17647949, Length=452, Percent_Identity=31.4159292035398, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24641198, Length=253, Percent_Identity=29.6442687747036, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 48706; Mature: 48706

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDALSGKLGDVFDRLRRRGALSESDVIEAMRDIRLALLEADVALPVVRDFIAKVRLQAV
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEVLRAVSPGQQVVKIVNDALVDALGGEGAVPLNLNAASPIPFLMVGLQGSGKTTTSGK
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCC
IALLLKEKQRKKVLLASLDTQRPAAQLQLAQLAERAGVASLPIVPGETPVQIARRAMETG
EEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
RREVFDVVILDTAGRLAIDQALMDEVKAIRDVTAPAETLLVVDAMTGQDALATATAFNEA
HHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCHHHHHHHHHHHH
VSITGIVMTRLDGDARGGAALSMRAVTGAPIKLMGMGEKLDALEPFHPERIAGRILGMGD
HHHHHHEEEECCCCCCCCCEEEEEEECCCCEEEEECCCHHCCCCCCCHHHHHHHHCCHHH
IVSLVEKAAENVDQQKAEQLAKKMARGKFDLEDYAEQLKQITKMGSLSGIMGMLPGVGKI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KQQLAEADLDTSILKRQAAIISSMTKAERANPDIMKASRKKRVAAGSGTSVQEVNRLLKQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FEQMKDMMKRAQKLGQKGLARGGLAALLPQGGGRRPF
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MFDALSGKLGDVFDRLRRRGALSESDVIEAMRDIRLALLEADVALPVVRDFIAKVRLQAV
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEVLRAVSPGQQVVKIVNDALVDALGGEGAVPLNLNAASPIPFLMVGLQGSGKTTTSGK
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCC
IALLLKEKQRKKVLLASLDTQRPAAQLQLAQLAERAGVASLPIVPGETPVQIARRAMETG
EEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
RREVFDVVILDTAGRLAIDQALMDEVKAIRDVTAPAETLLVVDAMTGQDALATATAFNEA
HHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCHHHHHHHHHHHH
VSITGIVMTRLDGDARGGAALSMRAVTGAPIKLMGMGEKLDALEPFHPERIAGRILGMGD
HHHHHHEEEECCCCCCCCCEEEEEEECCCCEEEEECCCHHCCCCCCCHHHHHHHHCCHHH
IVSLVEKAAENVDQQKAEQLAKKMARGKFDLEDYAEQLKQITKMGSLSGIMGMLPGVGKI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KQQLAEADLDTSILKRQAAIISSMTKAERANPDIMKASRKKRVAAGSGTSVQEVNRLLKQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FEQMKDMMKRAQKLGQKGLARGGLAALLPQGGGRRPF
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA