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The map label for this gene is thiL [H]

Identifier: 148261107

GI number: 148261107

Start: 2344836

End: 2345774

Strand: Reverse

Name: thiL [H]

Synonym: Acry_2116

Alternate gene names: 148261107

Gene position: 2345774-2344836 (Counterclockwise)

Preceding gene: 148261108

Following gene: 148261103

Centisome position: 69.21

GC content: 72.84

Gene sequence:

>939_bases
GTGAGCGGCGAGTTCGGCCGCATCGCCCGGTATTTCGCGCCGCTCGCCTCGGCGGAAGCGCTCGGCCTGGCCGACGATGC
CGCGCTCTGGACGCCGCCGGCCGGGCGCCAGGCCGTGCTGACGGTGGATCAGATGATCGAGGGCGTGCACTTCCTGCCGG
ATGATCCCGCCGATCTGGTCGCCCGCAAGCTGATGCGCCGGAATCTTTCCGATCTCGCCGCCATGGGCGCGCGGGCGGAG
GGATACCTGCTTACGACCGCCTTGCGCGCCGACACGCCCGAGACCTGGCTTTCGGCGTTTGCCGAAGGCCTTGCCGCCGA
CCAGGCACGGTTCGGCCTGCCGCTCTGGGGGGGCGACAGCTCGTCCACGCCCGGTCCGGTGATGACGTCGATCACCATGA
TCGGCAGTGTCGAGCCCGGGGCGGCGCTGCGGCGCGGTGGGGCGGTTGCGGGCGACGCGCTCTACGTCACCGGCACGATC
GGCGATGCGGCGCTCGGGCTGCATGCCGCGCGCGGCGAGATCGCCGATCCGACCGGCCAGTTCCGCGCGCGCCGCCTGCT
GCCCGAGCCCCGCATCGGCCTAGCGCTCGCGGGTCTCGTTCATGCCGCGATCGATGTCTCCGACGGGCTGGTGCAGGATC
TCGGCCATGTGTGCCGAGCATCGGGCTGCGGCGCGGTGATCGAGGCGGACCGCGTTCCGCTCTCGCCGGCGGCGCGGGCG
GCGGGACCCGCCTGGCGGGAGACGATCCTCACCGGCGGCGACGATTACGAATTGCTGATCGCCGCCCCGGCCGGATCGGA
CCACGAGTTGCGGCAGGCCTGCGCCGGCACGCCGCTCACGCGGATCGGCCATTTCGTGGCGGGGGCGCCCGCGGTGACGG
CGGTGGACAAGGATGGCCGGCCGGTCACGCTGGCGCGAACCGGCTGGCAACATTTCTGA

Upstream 100 bases:

>100_bases
TTCCTCGAAGGCGATGCGGTGCAGATGGGCAACGCCGTGCTCGACCGGATTGCCCGCACGCTGCGCGAAGGCGAGTTCAC
CGACCCCGTCAGGGCATGAA

Downstream 100 bases:

>100_bases
CGAAGCGTCAGTTCTGCGGCGCCTTGAAGGCGACCTCCCGCTTGAGCGAGAACGGGTCGCTCGGGTCGCGCTGGTTCAGG
AGATCCTGCATCCGCAGTTC

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSGEFGRIARYFAPLASAEALGLADDAALWTPPAGRQAVLTVDQMIEGVHFLPDDPADLVARKLMRRNLSDLAAMGARAE
GYLLTTALRADTPETWLSAFAEGLAADQARFGLPLWGGDSSSTPGPVMTSITMIGSVEPGAALRRGGAVAGDALYVTGTI
GDAALGLHAARGEIADPTGQFRARRLLPEPRIGLALAGLVHAAIDVSDGLVQDLGHVCRASGCGAVIEADRVPLSPAARA
AGPAWRETILTGGDDYELLIAAPAGSDHELRQACAGTPLTRIGHFVAGAPAVTAVDKDGRPVTLARTGWQHF

Sequences:

>Translated_312_residues
MSGEFGRIARYFAPLASAEALGLADDAALWTPPAGRQAVLTVDQMIEGVHFLPDDPADLVARKLMRRNLSDLAAMGARAE
GYLLTTALRADTPETWLSAFAEGLAADQARFGLPLWGGDSSSTPGPVMTSITMIGSVEPGAALRRGGAVAGDALYVTGTI
GDAALGLHAARGEIADPTGQFRARRLLPEPRIGLALAGLVHAAIDVSDGLVQDLGHVCRASGCGAVIEADRVPLSPAARA
AGPAWRETILTGGDDYELLIAAPAGSDHELRQACAGTPLTRIGHFVAGAPAVTAVDKDGRPVTLARTGWQHF
>Mature_311_residues
SGEFGRIARYFAPLASAEALGLADDAALWTPPAGRQAVLTVDQMIEGVHFLPDDPADLVARKLMRRNLSDLAAMGARAEG
YLLTTALRADTPETWLSAFAEGLAADQARFGLPLWGGDSSSTPGPVMTSITMIGSVEPGAALRRGGAVAGDALYVTGTIG
DAALGLHAARGEIADPTGQFRARRLLPEPRIGLALAGLVHAAIDVSDGLVQDLGHVCRASGCGAVIEADRVPLSPAARAA
GPAWRETILTGGDDYELLIAAPAGSDHELRQACAGTPLTRIGHFVAGAPAVTAVDKDGRPVTLARTGWQHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=328, Percent_Identity=41.4634146341463, Blast_Score=181, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 32252; Mature: 32121

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEFGRIARYFAPLASAEALGLADDAALWTPPAGRQAVLTVDQMIEGVHFLPDDPADLV
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEEEEHHHHHCCCCCCCCCHHHHH
ARKLMRRNLSDLAAMGARAEGYLLTTALRADTPETWLSAFAEGLAADQARFGLPLWGGDS
HHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEECCCC
SSTPGPVMTSITMIGSVEPGAALRRGGAVAGDALYVTGTIGDAALGLHAARGEIADPTGQ
CCCCCCHHHHEEEECCCCCCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCHHH
FRARRLLPEPRIGLALAGLVHAAIDVSDGLVQDLGHVCRASGCGAVIEADRVPLSPAARA
HHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHH
AGPAWRETILTGGDDYELLIAAPAGSDHELRQACAGTPLTRIGHFVAGAPAVTAVDKDGR
CCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCC
PVTLARTGWQHF
EEEEECCCCCCC
>Mature Secondary Structure 
SGEFGRIARYFAPLASAEALGLADDAALWTPPAGRQAVLTVDQMIEGVHFLPDDPADLV
CCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEEEEHHHHHCCCCCCCCCHHHHH
ARKLMRRNLSDLAAMGARAEGYLLTTALRADTPETWLSAFAEGLAADQARFGLPLWGGDS
HHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEECCCC
SSTPGPVMTSITMIGSVEPGAALRRGGAVAGDALYVTGTIGDAALGLHAARGEIADPTGQ
CCCCCCHHHHEEEECCCCCCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCHHH
FRARRLLPEPRIGLALAGLVHAAIDVSDGLVQDLGHVCRASGCGAVIEADRVPLSPAARA
HHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHH
AGPAWRETILTGGDDYELLIAAPAGSDHELRQACAGTPLTRIGHFVAGAPAVTAVDKDGR
CCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCC
PVTLARTGWQHF
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]