BacMap

Definition	Acidiphilium cryptum JF-5 chromosome, complete genome.
Accession	NC_009484
Length	3,389,227

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The map label for this gene is fabG [H]

Identifier: 148260854

GI number: 148260854

Start: 2051564

End: 2052337

Strand: Reverse

Name: fabG [H]

Synonym: Acry_1860

Alternate gene names: 148260854

Gene position: 2052337-2051564 (Counterclockwise)

Preceding gene: 148260857

Following gene: 148260853

Centisome position: 60.55

GC content: 70.93

Gene sequence:

>774_bases
ATGGACGGTCTGCCGGCGCGCGAGGGGAACATGAAACGGGCGCTGGAGGGGCGGGTTGCGGTCGTCACCGGCGCCGGCGG
CGCGATCGGCGCGGCGGTGGCCCGCGCGCTCGCGGCCGAGGGGGCGGTGCTCGTGCTGGTGGACATCGCCGCCGGGAAGC
TGGCCGCGACCGGCGCCGAACTCGGCGCTGCGGCGCGGGTGGTCGTGGCCGATCTCGGCGATCCGGACGCCATCGCCGCG
GCGGCTGCCGTCGTGAACGATAAGGGCGGCGCCGACATTCTCGTCAACAATGCCGGCATTCTCTCGAACCGCAAGATCGA
CGCGACCGATCTCGCCGAATGGCGGCGCGTGCAGGCGGTGAATCTCGACGGCGCCTTCCTGCTCACCCGCGCCCTGCTGC
CGGCGATGCGGCGGAAGGGCTGGGGGCGGATCGTGAATATCGCCTCCTACGCGGCGAAATGCGGCGGGCTGACGGCGGGC
ACGGCCTATACGGTGTCGAAGGCGGGGCTGGTGGGGCTGACCTTTTCGGTCGCCCGCGAGGTGGCCGCCGAGGGGATCAC
CGTCAACGCCATCGCGCCGGCCTACGTGATGTCGCCGATGGTGTCGGAAATGCTGACCGAGGCGCAGCGCGCCGAACAGC
TTGCGCAGATCCCCGTCGGCCGGTTCTGCCGGCCGGAGGAAGTGGCGCATGCGGTGATGTTCCTGGCCTCGCCGCTGGCG
GCCTCGATCACCGGCGAGGTGATCGACATGAATGGCGGATTGCAGTTTGACTGA

Upstream 100 bases:

>100_bases
CGGCATGGACGCAAGGCGTTTTGCACCGATCATACCGGGGGCGCGACATGTTTGACAGTCGTGATTTACCAATATACCGG
TATTTCGGGAGGGTCGATAC

Downstream 100 bases:

>100_bases
CGAGCCGTTATATCCGGCACGGCTCGCGTCGCTGCCGGCGGACATCGCCCGCCCGGGCTATGACCGCGATGCGGTGCGGA
CCGGCATCCTGCATCTCGGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDGLPAREGNMKRALEGRVAVVTGAGGAIGAAVARALAAEGAVLVLVDIAAGKLAATGAELGAAARVVVADLGDPDAIAA
AAAVVNDKGGADILVNNAGILSNRKIDATDLAEWRRVQAVNLDGAFLLTRALLPAMRRKGWGRIVNIASYAAKCGGLTAG
TAYTVSKAGLVGLTFSVAREVAAEGITVNAIAPAYVMSPMVSEMLTEAQRAEQLAQIPVGRFCRPEEVAHAVMFLASPLA
ASITGEVIDMNGGLQFD

Sequences:

>Translated_257_residues
MDGLPAREGNMKRALEGRVAVVTGAGGAIGAAVARALAAEGAVLVLVDIAAGKLAATGAELGAAARVVVADLGDPDAIAA
AAAVVNDKGGADILVNNAGILSNRKIDATDLAEWRRVQAVNLDGAFLLTRALLPAMRRKGWGRIVNIASYAAKCGGLTAG
TAYTVSKAGLVGLTFSVAREVAAEGITVNAIAPAYVMSPMVSEMLTEAQRAEQLAQIPVGRFCRPEEVAHAVMFLASPLA
ASITGEVIDMNGGLQFD
>Mature_257_residues
MDGLPAREGNMKRALEGRVAVVTGAGGAIGAAVARALAAEGAVLVLVDIAAGKLAATGAELGAAARVVVADLGDPDAIAA
AAAVVNDKGGADILVNNAGILSNRKIDATDLAEWRRVQAVNLDGAFLLTRALLPAMRRKGWGRIVNIASYAAKCGGLTAG
TAYTVSKAGLVGLTFSVAREVAAEGITVNAIAPAYVMSPMVSEMLTEAQRAEQLAQIPVGRFCRPEEVAHAVMFLASPLA
ASITGEVIDMNGGLQFD

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=33.2046332046332, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI66933014, Length=244, Percent_Identity=31.1475409836066, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=32.8, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=32.9218106995885, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=32.3076923076923, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=29.0836653386454, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4504505, Length=254, Percent_Identity=31.1023622047244, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=32.7935222672065, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI142976729, Length=237, Percent_Identity=30.379746835443, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI210032110, Length=202, Percent_Identity=31.1881188118812, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=259, Percent_Identity=32.046332046332, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=34.6733668341709, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=29.3650793650794, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=30.3846153846154, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI59889578, Length=210, Percent_Identity=30, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI10190704, Length=263, Percent_Identity=28.8973384030418, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=34, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI19743808, Length=221, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=30.8900523560209, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=230, Percent_Identity=26.9565217391304, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=27.3858921161826, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI166795268, Length=206, Percent_Identity=31.5533980582524, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI150247226, Length=210, Percent_Identity=30.4761904761905, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=33.1550802139037, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI157739938, Length=199, Percent_Identity=27.6381909547739, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=40.495867768595, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=37.6, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=35.7723577235772, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=31.6872427983539, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=33.8582677165354, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=32.0987654320988, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=31.3253012048193, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=34.136546184739, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=30.6451612903226, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=33.1983805668016, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787820, Length=236, Percent_Identity=25.8474576271186, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=29.3877551020408, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=28.515625, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=32.9218106995885, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=32.4, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=32.9411764705882, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=33.0769230769231, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=34.5177664974619, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=28.7878787878788, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=265, Percent_Identity=30.5660377358491, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=259, Percent_Identity=31.2741312741313, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=31.7829457364341, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=237, Percent_Identity=30.379746835443, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=206, Percent_Identity=30.0970873786408, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=31.2820512820513, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=29.5019157088123, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=32.6996197718631, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=30.1158301158301, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=268, Percent_Identity=29.4776119402985, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=29.2307692307692, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=28.1853281853282, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=199, Percent_Identity=28.643216080402, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=203, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=256, Percent_Identity=28.125, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.8461538461538, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=29.5880149812734, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=28.7449392712551, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=26.5151515151515, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17558628, Length=205, Percent_Identity=30.2439024390244, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=27.7566539923954, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=29.5719844357977, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=28.6792452830189, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=26.0700389105058, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=25.8687258687259, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=27.0161290322581, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=26.7175572519084, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=27.4436090225564, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=28.2527881040892, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=259, Percent_Identity=30.5019305019305, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=34.9593495934959, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=39.0438247011952, Blast_Score=121, Evalue=6e-28,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=34.7490347490347, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=36.0824742268041, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=32.9268292682927, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=33.0739299610895, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=32.9365079365079, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357673, Length=204, Percent_Identity=30.3921568627451, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=31.7829457364341, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI161076933, Length=195, Percent_Identity=34.3589743589744, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28574402, Length=211, Percent_Identity=31.7535545023697, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24584748, Length=210, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24584744, Length=211, Percent_Identity=31.7535545023697, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21358495, Length=208, Percent_Identity=27.8846153846154, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=29.1666666666667, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648693, Length=256, Percent_Identity=30.078125, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355889, Length=256, Percent_Identity=30.078125, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26088; Mature: 26088

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGLPAREGNMKRALEGRVAVVTGAGGAIGAAVARALAAEGAVLVLVDIAAGKLAATGAE
CCCCCCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCHH
LGAAARVVVADLGDPDAIAAAAAVVNDKGGADILVNNAGILSNRKIDATDLAEWRRVQAV
HCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHEEEE
NLDGAFLLTRALLPAMRRKGWGRIVNIASYAAKCGGLTAGTAYTVSKAGLVGLTFSVARE
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHH
VAAEGITVNAIAPAYVMSPMVSEMLTEAQRAEQLAQIPVGRFCRPEEVAHAVMFLASPLA
HHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ASITGEVIDMNGGLQFD
HHHCCEEEECCCCCCCC
>Mature Secondary Structure
MDGLPAREGNMKRALEGRVAVVTGAGGAIGAAVARALAAEGAVLVLVDIAAGKLAATGAE
CCCCCCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCHH
LGAAARVVVADLGDPDAIAAAAAVVNDKGGADILVNNAGILSNRKIDATDLAEWRRVQAV
HCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHEEEE
NLDGAFLLTRALLPAMRRKGWGRIVNIASYAAKCGGLTAGTAYTVSKAGLVGLTFSVARE
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHH
VAAEGITVNAIAPAYVMSPMVSEMLTEAQRAEQLAQIPVGRFCRPEEVAHAVMFLASPLA
HHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ASITGEVIDMNGGLQFD
HHHCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]