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The map label for this gene is ppiD [H]

Identifier: 148260238

GI number: 148260238

Start: 1374925

End: 1376811

Strand: Reverse

Name: ppiD [H]

Synonym: Acry_1235

Alternate gene names: 148260238

Gene position: 1376811-1374925 (Counterclockwise)

Preceding gene: 148260243

Following gene: 148260237

Centisome position: 40.62

GC content: 70.85

Gene sequence:

>1887_bases
ATGCTTTCGATGATCCGCCAACTGCTCGACAACTGGATCGTGCGCGCGTTTTTCGTCGTGCTGATCGGCGTGTTCGTGTT
CTGGGGCGTCTCCAGCGTGGTGATGGGCATCGGCGCGTCCGACGCGATCGCGACGGTGGGCGGGCAGCCGATCAAGATCG
AGGCGGTGAATGCCGCCTACCAGCGCACGCTGAACGCCTATGCGACGCAGAACAGCGGCCGCGAGCCGAGCAAGGGCGAG
CGCCGGCTGTTCGCCGACCAGGCGCTGGGCACCGCGATCGACCGCGCGGCGATGGAGCTGGAGGCGCGGCGGATGGGGGT
GGTGGCACCGCCCGCGGCGATCCGCCAGCAGGTCTTCGCGATTCCGGCGTTCCACGGGCCGGACGGCAAGTTCGACAAGG
CGACGTTCAACGCCGTGCTCGCCAACCACAACCTGACGCCGGCGGCGTTCATGGCCGAGATCGCCAGCGGGCTGAAGACG
TCGCAGATCATCGATGCGGTGACCGCCGGGGTGAGCGCGCCGGCGCCGCTGGTGGACCAGATCTTCGCCTATGCCGCGCA
GGAGCGGACGGTGCAGTTCGCGCAGCTGCCCTTCGCCGCCGCCAACCCGCCGCCGGCGCCGGCCGAGACCGTGCTGCGGC
GCTACTGGCGGGATCATCCGGGGCGGTTCTCGACGCCGGCGCTGCGCGATGCGGACGTCGTCGTGCTCTCGCCGGCGCTG
ATCGCCAGGGGCGAGGCGGTGTCGCAGGCGGAGATCGCGGCGCAGTATCAGCAGGAGAAGGCGAAATTCGCGCAGACGCC
GACGCGGACCGTCGAGATCATCACCGCGGAGGATGCGAAGAGCGCCGCGGCGCTGGCCAATGCGTGGAAGGGCGGGGCCG
ACTGGGCGGCGATGCAGAAGGCGGCCGCCGCGGCGACGGCCACCGCCATCGTCATGACCGACGCGAAGCCCTCCGACCTG
CCCTCGGCCACGCTGGCCAAGGCGGCGTTCGCGGCGACGCCGGGCGAGGTTTCCGCGCCGGTGAAGGGGGCGCTCGGCAC
CTATGTGTTCAAGGTGACGAAGGCCGTCGCCGGCGGCGACAAGCCGCTCTCGGCGGTGGCGGACCAGATCCGCGCCGAGA
TCCAGCTGCGCAAGGCGCGCAACGTGGTGGACAACACGCTGAGCCACCTGCAGGACGCGCTGGCGGGCAGCACGGCGCTC
GGCAAGCTGCCGGCGAGCCTGCATCTCGCCAAGGCGCGGGTGAGCGTGGACCGCGAGGGCATGACGGTGGACGGCAAGCC
GGCGGGGATTCCCGGGCCGGCGGCGCTGCGGCAGGCGATCGTCAAGGCGATTTTCGCCACCGCGCCGGGCAACACCCCGC
AGGCGGTGAGCGGGCCGGGCGACAGCTATTACGCCATCGCGGTGCACCGGATCATCAAGCCGGCGCTCAAGCCCTATGAC
AAGGTGAAGGCCGACGTGCTGGCCGACTGGACCGGCGCGCAGGTGGAGCGGCAGGAGGAGGTGGCGGCGGCGAAGCTGCT
GACCGCGGTGAAGGGTGGCAAGACCCTGGCGGCGGCGGCCTCGGCGGCGGGGCTGACGGTGACGACCTCGGCGCCGATGA
CGCGCGCGAAGCCAGCCAAGGGCGTGCCGCCGCAGCTCGCCCAGGTGGCGTTCAGCCTCAAGAAGGGCGCGCCCACCATG
GTGCAGACGCAGGAGGGCTTCGTCGTCGGCGTGGTGAGCGACATCGCCGAGCCGAAGCCGGGCAGCGACAAGGCGTTCCA
CCAGCGGGTGGCCGATTCGCTCGGCCAGTCGATGCAGGAAGACGTGCTGCAGACCTATGCCGCGGCGCTGCGCCAGCGCG
ACCATGTGAAGATCAACACGAAGCTGCTGAACCAGATCAGCAATTGA

Upstream 100 bases:

>100_bases
CCTGACGTGGCGCGACCGAGGTAGACGAGGCGGGGCCGGGTGGCAATCGGGCGCGCCCGTGGTAAGACGCGGCTTTCCCG
CTGGATGAGGGTTCTGCCGC

Downstream 100 bases:

>100_bases
GGCCAGCGAGATGACACCCGAGACCGACCAGCACGCCCGTTTCCGCGCCGCCTACGATGCCGGGCGGGGCGCGCTGGCCT
GGCGACTGCTCGCCGCCGAC

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MLSMIRQLLDNWIVRAFFVVLIGVFVFWGVSSVVMGIGASDAIATVGGQPIKIEAVNAAYQRTLNAYATQNSGREPSKGE
RRLFADQALGTAIDRAAMELEARRMGVVAPPAAIRQQVFAIPAFHGPDGKFDKATFNAVLANHNLTPAAFMAEIASGLKT
SQIIDAVTAGVSAPAPLVDQIFAYAAQERTVQFAQLPFAAANPPPAPAETVLRRYWRDHPGRFSTPALRDADVVVLSPAL
IARGEAVSQAEIAAQYQQEKAKFAQTPTRTVEIITAEDAKSAAALANAWKGGADWAAMQKAAAAATATAIVMTDAKPSDL
PSATLAKAAFAATPGEVSAPVKGALGTYVFKVTKAVAGGDKPLSAVADQIRAEIQLRKARNVVDNTLSHLQDALAGSTAL
GKLPASLHLAKARVSVDREGMTVDGKPAGIPGPAALRQAIVKAIFATAPGNTPQAVSGPGDSYYAIAVHRIIKPALKPYD
KVKADVLADWTGAQVERQEEVAAAKLLTAVKGGKTLAAAASAAGLTVTTSAPMTRAKPAKGVPPQLAQVAFSLKKGAPTM
VQTQEGFVVGVVSDIAEPKPGSDKAFHQRVADSLGQSMQEDVLQTYAAALRQRDHVKINTKLLNQISN

Sequences:

>Translated_628_residues
MLSMIRQLLDNWIVRAFFVVLIGVFVFWGVSSVVMGIGASDAIATVGGQPIKIEAVNAAYQRTLNAYATQNSGREPSKGE
RRLFADQALGTAIDRAAMELEARRMGVVAPPAAIRQQVFAIPAFHGPDGKFDKATFNAVLANHNLTPAAFMAEIASGLKT
SQIIDAVTAGVSAPAPLVDQIFAYAAQERTVQFAQLPFAAANPPPAPAETVLRRYWRDHPGRFSTPALRDADVVVLSPAL
IARGEAVSQAEIAAQYQQEKAKFAQTPTRTVEIITAEDAKSAAALANAWKGGADWAAMQKAAAAATATAIVMTDAKPSDL
PSATLAKAAFAATPGEVSAPVKGALGTYVFKVTKAVAGGDKPLSAVADQIRAEIQLRKARNVVDNTLSHLQDALAGSTAL
GKLPASLHLAKARVSVDREGMTVDGKPAGIPGPAALRQAIVKAIFATAPGNTPQAVSGPGDSYYAIAVHRIIKPALKPYD
KVKADVLADWTGAQVERQEEVAAAKLLTAVKGGKTLAAAASAAGLTVTTSAPMTRAKPAKGVPPQLAQVAFSLKKGAPTM
VQTQEGFVVGVVSDIAEPKPGSDKAFHQRVADSLGQSMQEDVLQTYAAALRQRDHVKINTKLLNQISN
>Mature_628_residues
MLSMIRQLLDNWIVRAFFVVLIGVFVFWGVSSVVMGIGASDAIATVGGQPIKIEAVNAAYQRTLNAYATQNSGREPSKGE
RRLFADQALGTAIDRAAMELEARRMGVVAPPAAIRQQVFAIPAFHGPDGKFDKATFNAVLANHNLTPAAFMAEIASGLKT
SQIIDAVTAGVSAPAPLVDQIFAYAAQERTVQFAQLPFAAANPPPAPAETVLRRYWRDHPGRFSTPALRDADVVVLSPAL
IARGEAVSQAEIAAQYQQEKAKFAQTPTRTVEIITAEDAKSAAALANAWKGGADWAAMQKAAAAATATAIVMTDAKPSDL
PSATLAKAAFAATPGEVSAPVKGALGTYVFKVTKAVAGGDKPLSAVADQIRAEIQLRKARNVVDNTLSHLQDALAGSTAL
GKLPASLHLAKARVSVDREGMTVDGKPAGIPGPAALRQAIVKAIFATAPGNTPQAVSGPGDSYYAIAVHRIIKPALKPYD
KVKADVLADWTGAQVERQEEVAAAKLLTAVKGGKTLAAAASAAGLTVTTSAPMTRAKPAKGVPPQLAQVAFSLKKGAPTM
VQTQEGFVVGVVSDIAEPKPGSDKAFHQRVADSLGQSMQEDVLQTYAAALRQRDHVKINTKLLNQISN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=657, Percent_Identity=25.4185692541857, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 65684; Mature: 65684

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSMIRQLLDNWIVRAFFVVLIGVFVFWGVSSVVMGIGASDAIATVGGQPIKIEAVNAAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEHHHHH
QRTLNAYATQNSGREPSKGERRLFADQALGTAIDRAAMELEARRMGVVAPPAAIRQQVFA
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IPAFHGPDGKFDKATFNAVLANHNLTPAAFMAEIASGLKTSQIIDAVTAGVSAPAPLVDQ
CCCEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHH
IFAYAAQERTVQFAQLPFAAANPPPAPAETVLRRYWRDHPGRFSTPALRDADVVVLSPAL
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHH
IARGEAVSQAEIAAQYQQEKAKFAQTPTRTVEIITAEDAKSAAALANAWKGGADWAAMQK
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHH
AAAAATATAIVMTDAKPSDLPSATLAKAAFAATPGEVSAPVKGALGTYVFKVTKAVAGGD
HHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
KPLSAVADQIRAEIQLRKARNVVDNTLSHLQDALAGSTALGKLPASLHLAKARVSVDREG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHEECCCC
MTVDGKPAGIPGPAALRQAIVKAIFATAPGNTPQAVSGPGDSYYAIAVHRIIKPALKPYD
CEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHH
KVKADVLADWTGAQVERQEEVAAAKLLTAVKGGKTLAAAASAAGLTVTTSAPMTRAKPAK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECCCCCCCCCCCC
GVPPQLAQVAFSLKKGAPTMVQTQEGFVVGVVSDIAEPKPGSDKAFHQRVADSLGQSMQE
CCCHHHHHHHHHHHCCCCCEEEECCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DVLQTYAAALRQRDHVKINTKLLNQISN
HHHHHHHHHHHCCCCEEEHHHHHHHHCC
>Mature Secondary Structure
MLSMIRQLLDNWIVRAFFVVLIGVFVFWGVSSVVMGIGASDAIATVGGQPIKIEAVNAAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEHHHHH
QRTLNAYATQNSGREPSKGERRLFADQALGTAIDRAAMELEARRMGVVAPPAAIRQQVFA
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IPAFHGPDGKFDKATFNAVLANHNLTPAAFMAEIASGLKTSQIIDAVTAGVSAPAPLVDQ
CCCEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHH
IFAYAAQERTVQFAQLPFAAANPPPAPAETVLRRYWRDHPGRFSTPALRDADVVVLSPAL
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHH
IARGEAVSQAEIAAQYQQEKAKFAQTPTRTVEIITAEDAKSAAALANAWKGGADWAAMQK
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHH
AAAAATATAIVMTDAKPSDLPSATLAKAAFAATPGEVSAPVKGALGTYVFKVTKAVAGGD
HHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
KPLSAVADQIRAEIQLRKARNVVDNTLSHLQDALAGSTALGKLPASLHLAKARVSVDREG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHEECCCC
MTVDGKPAGIPGPAALRQAIVKAIFATAPGNTPQAVSGPGDSYYAIAVHRIIKPALKPYD
CEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHH
KVKADVLADWTGAQVERQEEVAAAKLLTAVKGGKTLAAAASAAGLTVTTSAPMTRAKPAK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECCCCCCCCCCCC
GVPPQLAQVAFSLKKGAPTMVQTQEGFVVGVVSDIAEPKPGSDKAFHQRVADSLGQSMQE
CCCHHHHHHHHHHHCCCCCEEEECCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DVLQTYAAALRQRDHVKINTKLLNQISN
HHHHHHHHHHHCCCCEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]