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The map label for this gene is coaD

Identifier: 148260182

GI number: 148260182

Start: 1313303

End: 1313812

Strand: Reverse

Name: coaD

Synonym: Acry_1178

Alternate gene names: 148260182

Gene position: 1313812-1313303 (Counterclockwise)

Preceding gene: 148260183

Following gene: 148260181

Centisome position: 38.76

GC content: 62.75

Gene sequence:

>510_bases
ATGGCTGATGGCGGTCTGATCGGTCTGTATCCGGGAACTTTCGATCCGATCACCAACGGGCATCTCGACATTATCGGCCG
CGCCGCCCAGCTCTGCTCGAAGCTGGTCATCGGCGTGGCCCGCAATGCCGGCAAGGGGCCGCTGTTTCCCACCGCCGAGC
GCGTCGAGATGGTCCGCGCCGAGATCGCGCCGATCGCCGAACGCACGGGCACCGAAATCGATGTGCAGGCGTTCGATTCG
CTGCTGATCGCCTTTGCCCAGCAGGTCAGCGCACAAGTGATCGTGCGCGGGTTGCGCGCCGTCTCCGACTTCGATTACGA
GTTCCAGATGGCCGGGATGAATGCACGACTCGACCAGCGGATCGAGACGATCTTCCTGATGGCAAGCGAGCGGCACCAGT
TCATCTCGTCGCGTTTCGTCAAGGAGATCGCCCAGCTGGGCGGCGACATCTCGAGCTTCGTTCCGAAACTGACGTTGGAG
AGGACCCTTCGCCGGGTTGGCAGACCATGA

Upstream 100 bases:

>100_bases
GCGATGGGCGTGACGCTTGTGCGGGTGGAAAAGGACGAACAGGTGACCAGCGTCTTCCCCGTCCTCGACGACAGCGGAGA
CGAAGCGGGGGAGGAACAGG

Downstream 100 bases:

>100_bases
TCATCAGACGCCGCACGCTTCTCGCCGCCGCCGCTTCCACCCCCCTTGCCGGAGTTTTCATGTCCGAATCCGCTTCCGCC
GCCAGCACGTCGAACACCAT

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MADGGLIGLYPGTFDPITNGHLDIIGRAAQLCSKLVIGVARNAGKGPLFPTAERVEMVRAEIAPIAERTGTEIDVQAFDS
LLIAFAQQVSAQVIVRGLRAVSDFDYEFQMAGMNARLDQRIETIFLMASERHQFISSRFVKEIAQLGGDISSFVPKLTLE
RTLRRVGRP

Sequences:

>Translated_169_residues
MADGGLIGLYPGTFDPITNGHLDIIGRAAQLCSKLVIGVARNAGKGPLFPTAERVEMVRAEIAPIAERTGTEIDVQAFDS
LLIAFAQQVSAQVIVRGLRAVSDFDYEFQMAGMNARLDQRIETIFLMASERHQFISSRFVKEIAQLGGDISSFVPKLTLE
RTLRRVGRP
>Mature_168_residues
ADGGLIGLYPGTFDPITNGHLDIIGRAAQLCSKLVIGVARNAGKGPLFPTAERVEMVRAEIAPIAERTGTEIDVQAFDSL
LIAFAQQVSAQVIVRGLRAVSDFDYEFQMAGMNARLDQRIETIFLMASERHQFISSRFVKEIAQLGGDISSFVPKLTLER
TLRRVGRP

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=149, Percent_Identity=42.9530201342282, Blast_Score=139, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_ACICJ (A5FXQ8)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001234309.1
- ProteinModelPortal:   A5FXQ8
- SMR:   A5FXQ8
- STRING:   A5FXQ8
- GeneID:   5161655
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_1178
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- BioCyc:   ACRY349163:ACRY_1178-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18520; Mature: 18388

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADGGLIGLYPGTFDPITNGHLDIIGRAAQLCSKLVIGVARNAGKGPLFPTAERVEMVRA
CCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
EIAPIAERTGTEIDVQAFDSLLIAFAQQVSAQVIVRGLRAVSDFDYEFQMAGMNARLDQR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHH
IETIFLMASERHQFISSRFVKEIAQLGGDISSFVPKLTLERTLRRVGRP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADGGLIGLYPGTFDPITNGHLDIIGRAAQLCSKLVIGVARNAGKGPLFPTAERVEMVRA
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
EIAPIAERTGTEIDVQAFDSLLIAFAQQVSAQVIVRGLRAVSDFDYEFQMAGMNARLDQR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHH
IETIFLMASERHQFISSRFVKEIAQLGGDISSFVPKLTLERTLRRVGRP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA