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The map label for this gene is yedX [C]

Identifier: 148260156

GI number: 148260156

Start: 1283213

End: 1283563

Strand: Reverse

Name: yedX [C]

Synonym: Acry_1152

Alternate gene names: 148260156

Gene position: 1283563-1283213 (Counterclockwise)

Preceding gene: 148260157

Following gene: 148260155

Centisome position: 37.87

GC content: 66.95

Gene sequence:

>351_bases
ATGACTGACCTGACCACGCATGTTCTCGACACTGCCCACGGCATTCCGGCGGCCGGTGTGCGTATCCGCCTGTTCGCTGC
CGGAGCGGCCGGAGGGCCCCTGGCCGAAGCCGAGACGGATGCTAACGGCCGCGCGAAGATTGTGCCCGCGAACGGCGTGG
CCTTCGATTCCGGCAGCTATGACCTCGTGTTTTCCGTCGGCGCCTATTTCGGCGCGAAGGGCGCGGCCGAGCCGGCACCG
CGCTTTCTGGACGATGTCGTGATCCGCTTCGGTCTCCGCGCCGGGGCCGCGCACCTTCATGTCCCGCTGCTGATCTCGCC
GTTCGGCTACACGACCTATCGGGGACAATGA

Upstream 100 bases:

>100_bases
ACCGGATCATAAGCGGGGAATTATATCGACAATTTCGGATCGCGGGCGCGGCAGCGGGCTGCCACCATCGCCCGCGCATG
AGAGGAAACGGACCGGATCG

Downstream 100 bases:

>100_bases
CGACAATGACGGCCTATATGGCGCAATGGGCGATGGCCCTGCTGATCTGGCTCCACGTGATCGCGGCGATCGCCTGGATC
GGCGAATCCTTCTACTTCGT

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase; HIUHase [H]

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MTDLTTHVLDTAHGIPAAGVRIRLFAAGAAGGPLAEAETDANGRAKIVPANGVAFDSGSYDLVFSVGAYFGAKGAAEPAP
RFLDDVVIRFGLRAGAAHLHVPLLISPFGYTTYRGQ

Sequences:

>Translated_116_residues
MTDLTTHVLDTAHGIPAAGVRIRLFAAGAAGGPLAEAETDANGRAKIVPANGVAFDSGSYDLVFSVGAYFGAKGAAEPAP
RFLDDVVIRFGLRAGAAHLHVPLLISPFGYTTYRGQ
>Mature_115_residues
TDLTTHVLDTAHGIPAAGVRIRLFAAGAAGGPLAEAETDANGRAKIVPANGVAFDSGSYDLVFSVGAYFGAKGAAEPAPR
FLDDVVIRFGLRAGAAHLHVPLLISPFGYTTYRGQ

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=113, Percent_Identity=35.3982300884956, Blast_Score=70, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534555, Length=115, Percent_Identity=34.7826086956522, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24652571, Length=114, Percent_Identity=35.0877192982456, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 11954; Mature: 11822

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLTTHVLDTAHGIPAAGVRIRLFAAGAAGGPLAEAETDANGRAKIVPANGVAFDSGSY
CCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCE
DLVFSVGAYFGAKGAAEPAPRFLDDVVIRFGLRAGAAHLHVPLLISPFGYTTYRGQ
EEEEEECHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECCC
>Mature Secondary Structure 
TDLTTHVLDTAHGIPAAGVRIRLFAAGAAGGPLAEAETDANGRAKIVPANGVAFDSGSY
CCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCE
DLVFSVGAYFGAKGAAEPAPRFLDDVVIRFGLRAGAAHLHVPLLISPFGYTTYRGQ
EEEEEECHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]