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The map label for this gene is yyaJ [H]

Identifier: 148260087

GI number: 148260087

Start: 1203515

End: 1204942

Strand: Reverse

Name: yyaJ [H]

Synonym: Acry_1080

Alternate gene names: 148260087

Gene position: 1204942-1203515 (Counterclockwise)

Preceding gene: 148260089

Following gene: 148260086

Centisome position: 35.55

GC content: 70.31

Gene sequence:

>1428_bases
ATGACCGCCACCGACAATACCGCGGGGCTCCTGCTCGCGCGGCTCGACCGGATCCCGAACTGGACCCTGCCCAGGCTCTA
CGCGCTGGTGATCGGCATCGGGTTTCTCTTCACCTTCTACGATATCTTCGACATCAACGTCTCCTTCATCCAGACCTGCA
TGGCGCTGGTGCCGGGCTGCACGCCGGCGAAATCGGGCGCCTATATCGGCCTGCCGGTGCTGCTCAATCTCGCCGGCTAC
GTGGTCGGCACGCTGGTCCTCAGCCCGCTGGCCGACCGGATGGGGCGGCGCGACCTGCTGCTGGTGACGATGATCCTCAC
CGGCATCGGCTCGGCGCTCACCGCCATCGTGCAGTCCTACGGCACCTTCGTCGCCGCGCGCGCCTTCACCGGCGTCGGCA
TCGGCGCCGACCTCGCCATCGTCAACACCTATATCGGCGAACTCGCCCCGGCCGGCGGCCGCGCCCGCTACACCTCGATG
ATCTTCATCTTCTCCGCCCTCGGCGCGGTGGCCGGCATCTGGCTCGGCCTCTGGCTGACCACGCCGCCCACGCCGCTGCC
GCTCGGCCTGCCCTTCGCCCTCGCCGGCAAGGGTTTTCCGGATGGCTGGCGCGTGATGTATCTCATCGGCGCGGCCCTCG
CGCTGGTCGGCGTGCTGCTGCGCTTCCAGCTGCCGGAATCGCCGCGCTGGCTCATCGCCCAGGGCCGCCTCGAGGAGGCC
GGCCAGGTCGTCGCCGACATGGAGGCCCGCGCCCACGCGATCTTCCCGCTGCCGCCGCTGCCCGAGCGCCTGCCGCCCGC
ACCAAGGCGCGAGGAGGCGATGCCCTTCAGCGCGATCTTCCGCAACGCCACCTACCGCAACCGCACGCTGCTGCTGACCG
TGATGTGGTTCCTCGCCTACATCACGGTCTATTCCTTCGCCGCCGGCTTCACCACGCTGCTCGCCGCCCTGCATTACCCG
CCGCCCGAGGCCGGGCTGATCACCGCGATGGGCACGTTCGGCTTCGTGCTCTGCGCCATCGTCGCCTATGTCTGGGGCGA
GCGGATGGAGCGCCGGCGCTGGACGCCGCTGGCGGCCCTCATCACCCTCGGCGGCGGCGTGCTCATCGCGCTGGGCGGGC
AGACGCTGTGGCTCTCGGTGATCGGCGCGATGATCGTCTTCTTCGGCTTCAACGTCTGGGTGCCGATCGCCTATGCCTGG
TCGGTCGAGAACTACCCGACCCGCGCGCGCACCACCGGCTTCGCCCTGGTCGACGGCATCGGCCATCTCGGCGGCGGCGT
CGGCATGATCGCGATCGCCCCGCTCATCCCGCGGCTCGGCGTCATGGCGGCGTTCCTGCTGATCGGCGGCTTCCTCGCGC
TGGCGGCGCTGGTCGCCCAGTTCGGCATCAGCACCCGCGCCCGCCGGCTCGACGACATCTCGCCCTGA

Upstream 100 bases:

>100_bases
GGCGCCCCGTGCCGCGCGGTTGACTTTCGTTTCACTTGCACTGCACCCTTTCCGCCGGCCCGGCGCAAGACCGGGCGCCC
GATAAACACCGGGAGGAACC

Downstream 100 bases:

>100_bases
CCTCGCGCCCCGAAATCCCGCCCCGAAATCCGGCGCGGACCAGCGGCGGAAGCCGGATCGCGCGACCGGCCCGCCCGCCG
CGCCGCGCCGGCTTCCGCCA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTATDNTAGLLLARLDRIPNWTLPRLYALVIGIGFLFTFYDIFDINVSFIQTCMALVPGCTPAKSGAYIGLPVLLNLAGY
VVGTLVLSPLADRMGRRDLLLVTMILTGIGSALTAIVQSYGTFVAARAFTGVGIGADLAIVNTYIGELAPAGGRARYTSM
IFIFSALGAVAGIWLGLWLTTPPTPLPLGLPFALAGKGFPDGWRVMYLIGAALALVGVLLRFQLPESPRWLIAQGRLEEA
GQVVADMEARAHAIFPLPPLPERLPPAPRREEAMPFSAIFRNATYRNRTLLLTVMWFLAYITVYSFAAGFTTLLAALHYP
PPEAGLITAMGTFGFVLCAIVAYVWGERMERRRWTPLAALITLGGGVLIALGGQTLWLSVIGAMIVFFGFNVWVPIAYAW
SVENYPTRARTTGFALVDGIGHLGGGVGMIAIAPLIPRLGVMAAFLLIGGFLALAALVAQFGISTRARRLDDISP

Sequences:

>Translated_475_residues
MTATDNTAGLLLARLDRIPNWTLPRLYALVIGIGFLFTFYDIFDINVSFIQTCMALVPGCTPAKSGAYIGLPVLLNLAGY
VVGTLVLSPLADRMGRRDLLLVTMILTGIGSALTAIVQSYGTFVAARAFTGVGIGADLAIVNTYIGELAPAGGRARYTSM
IFIFSALGAVAGIWLGLWLTTPPTPLPLGLPFALAGKGFPDGWRVMYLIGAALALVGVLLRFQLPESPRWLIAQGRLEEA
GQVVADMEARAHAIFPLPPLPERLPPAPRREEAMPFSAIFRNATYRNRTLLLTVMWFLAYITVYSFAAGFTTLLAALHYP
PPEAGLITAMGTFGFVLCAIVAYVWGERMERRRWTPLAALITLGGGVLIALGGQTLWLSVIGAMIVFFGFNVWVPIAYAW
SVENYPTRARTTGFALVDGIGHLGGGVGMIAIAPLIPRLGVMAAFLLIGGFLALAALVAQFGISTRARRLDDISP
>Mature_474_residues
TATDNTAGLLLARLDRIPNWTLPRLYALVIGIGFLFTFYDIFDINVSFIQTCMALVPGCTPAKSGAYIGLPVLLNLAGYV
VGTLVLSPLADRMGRRDLLLVTMILTGIGSALTAIVQSYGTFVAARAFTGVGIGADLAIVNTYIGELAPAGGRARYTSMI
FIFSALGAVAGIWLGLWLTTPPTPLPLGLPFALAGKGFPDGWRVMYLIGAALALVGVLLRFQLPESPRWLIAQGRLEEAG
QVVADMEARAHAIFPLPPLPERLPPAPRREEAMPFSAIFRNATYRNRTLLLTVMWFLAYITVYSFAAGFTTLLAALHYPP
PEAGLITAMGTFGFVLCAIVAYVWGERMERRRWTPLAALITLGGGVLIALGGQTLWLSVIGAMIVFFGFNVWVPIAYAWS
VENYPTRARTTGFALVDGIGHLGGGVGMIAIAPLIPRLGVMAAFLLIGGFLALAALVAQFGISTRARRLDDISP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI216548223, Length=210, Percent_Identity=29.5238095238095, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI7662270, Length=284, Percent_Identity=26.7605633802817, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI262399383, Length=282, Percent_Identity=25.886524822695, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI73695465, Length=298, Percent_Identity=24.8322147651007, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI166064021, Length=421, Percent_Identity=26.603325415677, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4507005, Length=403, Percent_Identity=27.0471464019851, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI166197673, Length=382, Percent_Identity=25.130890052356, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4506999, Length=354, Percent_Identity=24.8587570621469, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI24497490, Length=399, Percent_Identity=26.8170426065163, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI302148518, Length=364, Percent_Identity=23.3516483516484, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788074, Length=452, Percent_Identity=23.4513274336283, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786229, Length=421, Percent_Identity=26.3657957244656, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788068, Length=477, Percent_Identity=24.3186582809224, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082159, Length=296, Percent_Identity=28.0405405405405, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790463, Length=266, Percent_Identity=25.187969924812, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71986689, Length=416, Percent_Identity=24.5192307692308, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193202825, Length=416, Percent_Identity=24.5192307692308, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320745, Length=357, Percent_Identity=23.249299719888, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323512, Length=504, Percent_Identity=23.2142857142857, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221330907, Length=379, Percent_Identity=23.7467018469657, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 50877; Mature: 50746

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00178 AA_TRNA_LIGASE_I ; PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATDNTAGLLLARLDRIPNWTLPRLYALVIGIGFLFTFYDIFDINVSFIQTCMALVPGC
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
TPAKSGAYIGLPVLLNLAGYVVGTLVLSPLADRMGRRDLLLVTMILTGIGSALTAIVQSY
CCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GTFVAARAFTGVGIGADLAIVNTYIGELAPAGGRARYTSMIFIFSALGAVAGIWLGLWLT
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
TPPTPLPLGLPFALAGKGFPDGWRVMYLIGAALALVGVLLRFQLPESPRWLIAQGRLEEA
CCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHH
GQVVADMEARAHAIFPLPPLPERLPPAPRREEAMPFSAIFRNATYRNRTLLLTVMWFLAY
HHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
ITVYSFAAGFTTLLAALHYPPPEAGLITAMGTFGFVLCAIVAYVWGERMERRRWTPLAAL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ITLGGGVLIALGGQTLWLSVIGAMIVFFGFNVWVPIAYAWSVENYPTRARTTGFALVDGI
HHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHCCHHHHHHH
GHLGGGVGMIAIAPLIPRLGVMAAFLLIGGFLALAALVAQFGISTRARRLDDISP
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
>Mature Secondary Structure 
TATDNTAGLLLARLDRIPNWTLPRLYALVIGIGFLFTFYDIFDINVSFIQTCMALVPGC
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
TPAKSGAYIGLPVLLNLAGYVVGTLVLSPLADRMGRRDLLLVTMILTGIGSALTAIVQSY
CCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GTFVAARAFTGVGIGADLAIVNTYIGELAPAGGRARYTSMIFIFSALGAVAGIWLGLWLT
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
TPPTPLPLGLPFALAGKGFPDGWRVMYLIGAALALVGVLLRFQLPESPRWLIAQGRLEEA
CCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHH
GQVVADMEARAHAIFPLPPLPERLPPAPRREEAMPFSAIFRNATYRNRTLLLTVMWFLAY
HHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
ITVYSFAAGFTTLLAALHYPPPEAGLITAMGTFGFVLCAIVAYVWGERMERRRWTPLAAL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ITLGGGVLIALGGQTLWLSVIGAMIVFFGFNVWVPIAYAWSVENYPTRARTTGFALVDGI
HHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHCCHHHHHHH
GHLGGGVGMIAIAPLIPRLGVMAAFLLIGGFLALAALVAQFGISTRARRLDDISP
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]