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The map label for this gene is etfD [H]

Identifier: 148260065

GI number: 148260065

Start: 1177556

End: 1179190

Strand: Reverse

Name: etfD [H]

Synonym: Acry_1057

Alternate gene names: 148260065

Gene position: 1179190-1177556 (Counterclockwise)

Preceding gene: 148260069

Following gene: 148260064

Centisome position: 34.79

GC content: 66.85

Gene sequence:

>1635_bases
ATGTCAGACACAGTGCCGCCCCGGGAATCCATGGAATTCGACGTCGTCGTGGTCGGCGCCGGCCCGGCCGGCCTGTCGGC
GGCGATCAGGCTGAAACAGATCAACGCCGAGCTTTCGGTCTGCGTCGTCGAAAAAGGCGGCGAGGTCGGCGCGCATATTC
TCTCCGGCTGCGTGCTGGAACCGCGCGCGATGACCGAATTGCTGCCCGACGCCGATATCGGCGCGATCGAGTTCTCGGCG
AAGGCGGGCGAGGACCGTTTCCTGTTCCTCACCGAAACCGGCAGCCACCGCATGCCGACGCCGCCGCAGATGAACAATCA
CGGCAATTTCGTCGTCAGCCTCGGCAATGTGGTCCGCTTCCTGGGCGCGAAGGCGGAGGAGCTCGGCGTCGAGATCTATC
CCGGCTTCGCCGCGGCGGAGCTGCTGGTCGAGGAGGGCCGCGTCGCCGGCATCGCCACCGGCGACATGGGGATCGGCAAG
GACGGCCAGCCCACCGCGCAATACCAGCGCGGGATGGAACTGCGCGCGACATATACGGTGTTCGCCGAGGGCTGCCGCGG
CTCGCTCGGCAAGCAGCTGATGTCCCGCTTCGGCCTGCGCGACGGGGTCGATCCGCAGACCTACGGCATCGGCATCAAGG
AACTCTGGGAGGTGCCGGCGGAGCACCACAATCCCGGCATGGTCATGCACACGATCGGCTGGCCGCTCGATACCAAAACC
TATGGCGGCTCGTTCCTCTACCATCTGGGCGGCAACCTGATGGCCTACGGGTTCGTCATCGGACTCGACTACGAGAACCC
CTATCTCTCGCCCTTCGAGGAGATGCAGCGCTTCAAGACCCACAAGGCGATCCGTCCCTATTTCGAGGGCGCGAAGCGCA
TCTCCTACGGCGCGCGGGCGCTGAACGAGGGCGGGTTCCAGTCGATCCCCCGGCTCGCCTTTCCCGGCGGCGTGCTGGTC
GGCTGCGAGGCGGGATTCCTCAACGTGCCCAAGATCAAGGGCACCCACACCGCGATGAAATCCGGCATGCTCGCCGCCGA
GGCGATCGCCGAGGCGCTGTCCGGCAGCCGCCCCGCGACACTCGACGCCTTCCCCGAGAAGGTGCGCGCCTCCTGGCTCT
GGCCCGAGCTTCAGGCGGTGCGCAACATCCGCCCCGGCTTCGCGAAATTCGGCATGTGGGGCGGGCTGATCAACGCCGCG
TTCGAAACCTACGTCACCCGCGGCAAGTCGCCCTGGACGCTGCGCAACCACGCCGACAACACCGCGCTGAAGCCCGCCCG
CGACGCAACCCCCATCGCCTATCCGAAGCCCGATGGCGCGCTCACCTTCGACCGGCTGAGTTCGGTCTTCATCTCCAACA
CCAATCACGAGGAAAACCAGCCGGCGCATCTCACGCTGCTCGACCCGGCGAAGGCGATTTCGGTGAACTGGGCCGAATAC
CGCAGCCCGGAGACGCGCTACTGCCCGGCCGGCGTCTACGAGATCGTCGGCGCCGAGGCGGGCGATCCGAAGCTGCAGAT
CAACGCGCAGAACTGCGTGCACTGCAAGACCTGCGACATCAAGGACCCGACGCAGAACATCAACTGGGTGGTGCCCGAGG
GCGCCGGCGGCCCGGCCTATCCGGGCGGGATGTGA

Upstream 100 bases:

>100_bases
CTCCGCCTTGAGCGTTCATGGTCCGATTTGCGCCCGGGGCCGGGTTTTGCGCAATGCCGCGAGCTTCCCTATACGTTAAT
CGAAGCGCAGGAGGAATCGC

Downstream 100 bases:

>100_bases
GCATGGAGGCGGCGTGCTCCATCCGCGCCGCCGGCGAGGCCGACCTTGCCGCCGTGGCGCGGATCACCGCGGCGGCCTAC
GGGCCGTATGTCGCCGAATT

Product: electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSDTVPPRESMEFDVVVVGAGPAGLSAAIRLKQINAELSVCVVEKGGEVGAHILSGCVLEPRAMTELLPDADIGAIEFSA
KAGEDRFLFLTETGSHRMPTPPQMNNHGNFVVSLGNVVRFLGAKAEELGVEIYPGFAAAELLVEEGRVAGIATGDMGIGK
DGQPTAQYQRGMELRATYTVFAEGCRGSLGKQLMSRFGLRDGVDPQTYGIGIKELWEVPAEHHNPGMVMHTIGWPLDTKT
YGGSFLYHLGGNLMAYGFVIGLDYENPYLSPFEEMQRFKTHKAIRPYFEGAKRISYGARALNEGGFQSIPRLAFPGGVLV
GCEAGFLNVPKIKGTHTAMKSGMLAAEAIAEALSGSRPATLDAFPEKVRASWLWPELQAVRNIRPGFAKFGMWGGLINAA
FETYVTRGKSPWTLRNHADNTALKPARDATPIAYPKPDGALTFDRLSSVFISNTNHEENQPAHLTLLDPAKAISVNWAEY
RSPETRYCPAGVYEIVGAEAGDPKLQINAQNCVHCKTCDIKDPTQNINWVVPEGAGGPAYPGGM

Sequences:

>Translated_544_residues
MSDTVPPRESMEFDVVVVGAGPAGLSAAIRLKQINAELSVCVVEKGGEVGAHILSGCVLEPRAMTELLPDADIGAIEFSA
KAGEDRFLFLTETGSHRMPTPPQMNNHGNFVVSLGNVVRFLGAKAEELGVEIYPGFAAAELLVEEGRVAGIATGDMGIGK
DGQPTAQYQRGMELRATYTVFAEGCRGSLGKQLMSRFGLRDGVDPQTYGIGIKELWEVPAEHHNPGMVMHTIGWPLDTKT
YGGSFLYHLGGNLMAYGFVIGLDYENPYLSPFEEMQRFKTHKAIRPYFEGAKRISYGARALNEGGFQSIPRLAFPGGVLV
GCEAGFLNVPKIKGTHTAMKSGMLAAEAIAEALSGSRPATLDAFPEKVRASWLWPELQAVRNIRPGFAKFGMWGGLINAA
FETYVTRGKSPWTLRNHADNTALKPARDATPIAYPKPDGALTFDRLSSVFISNTNHEENQPAHLTLLDPAKAISVNWAEY
RSPETRYCPAGVYEIVGAEAGDPKLQINAQNCVHCKTCDIKDPTQNINWVVPEGAGGPAYPGGM
>Mature_543_residues
SDTVPPRESMEFDVVVVGAGPAGLSAAIRLKQINAELSVCVVEKGGEVGAHILSGCVLEPRAMTELLPDADIGAIEFSAK
AGEDRFLFLTETGSHRMPTPPQMNNHGNFVVSLGNVVRFLGAKAEELGVEIYPGFAAAELLVEEGRVAGIATGDMGIGKD
GQPTAQYQRGMELRATYTVFAEGCRGSLGKQLMSRFGLRDGVDPQTYGIGIKELWEVPAEHHNPGMVMHTIGWPLDTKTY
GGSFLYHLGGNLMAYGFVIGLDYENPYLSPFEEMQRFKTHKAIRPYFEGAKRISYGARALNEGGFQSIPRLAFPGGVLVG
CEAGFLNVPKIKGTHTAMKSGMLAAEAIAEALSGSRPATLDAFPEKVRASWLWPELQAVRNIRPGFAKFGMWGGLINAAF
ETYVTRGKSPWTLRNHADNTALKPARDATPIAYPKPDGALTFDRLSSVFISNTNHEENQPAHLTLLDPAKAISVNWAEYR
SPETRYCPAGVYEIVGAEAGDPKLQINAQNCVHCKTCDIKDPTQNINWVVPEGAGGPAYPGGM

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=555, Percent_Identity=57.2972972972973, Blast_Score=630, Evalue=0.0,
Organism=Escherichia coli, GI1787991, Length=330, Percent_Identity=30, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786227, Length=331, Percent_Identity=27.4924471299094, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87082155, Length=402, Percent_Identity=27.8606965174129, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144720, Length=554, Percent_Identity=55.0541516245487, Blast_Score=582, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6324932, Length=572, Percent_Identity=47.027972027972, Blast_Score=511, Evalue=1e-146,
Organism=Drosophila melanogaster, GI24652256, Length=548, Percent_Identity=57.4817518248175, Blast_Score=619, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 58730; Mature: 58598

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTVPPRESMEFDVVVVGAGPAGLSAAIRLKQINAELSVCVVEKGGEVGAHILSGCVLE
CCCCCCCCCCCEEEEEEEECCCCCCHHEEEEEEECCEEEEEEEECCCCHHHHHHHCCCCC
PRAMTELLPDADIGAIEFSAKAGEDRFLFLTETGSHRMPTPPQMNNHGNFVVSLGNVVRF
CHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHH
LGAKAEELGVEIYPGFAAAELLVEEGRVAGIATGDMGIGKDGQPTAQYQRGMELRATYTV
HCCCHHHCCEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHCCCEEEEEEEE
FAEGCRGSLGKQLMSRFGLRDGVDPQTYGIGIKELWEVPAEHHNPGMVMHTIGWPLDTKT
EHHCCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCC
YGGSFLYHLGGNLMAYGFVIGLDYENPYLSPFEEMQRFKTHKAIRPYFEGAKRISYGARA
CCCEEEEECCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNEGGFQSIPRLAFPGGVLVGCEAGFLNVPKIKGTHTAMKSGMLAAEAIAEALSGSRPAT
HCCCCHHHCCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCC
LDAFPEKVRASWLWPELQAVRNIRPGFAKFGMWGGLINAAFETYVTRGKSPWTLRNHADN
HHHCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCC
TALKPARDATPIAYPKPDGALTFDRLSSVFISNTNHEENQPAHLTLLDPAKAISVNWAEY
CCCCCCCCCCCCCCCCCCCCEEHHHHHHHEEECCCCCCCCCCEEEEECCCCEEEECHHHH
RSPETRYCPAGVYEIVGAEAGDPKLQINAQNCVHCKTCDIKDPTQNINWVVPEGAGGPAY
CCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCEEEECCCCCCCC
PGGM
CCCC
>Mature Secondary Structure 
SDTVPPRESMEFDVVVVGAGPAGLSAAIRLKQINAELSVCVVEKGGEVGAHILSGCVLE
CCCCCCCCCCEEEEEEEECCCCCCHHEEEEEEECCEEEEEEEECCCCHHHHHHHCCCCC
PRAMTELLPDADIGAIEFSAKAGEDRFLFLTETGSHRMPTPPQMNNHGNFVVSLGNVVRF
CHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHH
LGAKAEELGVEIYPGFAAAELLVEEGRVAGIATGDMGIGKDGQPTAQYQRGMELRATYTV
HCCCHHHCCEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHCCCEEEEEEEE
FAEGCRGSLGKQLMSRFGLRDGVDPQTYGIGIKELWEVPAEHHNPGMVMHTIGWPLDTKT
EHHCCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCC
YGGSFLYHLGGNLMAYGFVIGLDYENPYLSPFEEMQRFKTHKAIRPYFEGAKRISYGARA
CCCEEEEECCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNEGGFQSIPRLAFPGGVLVGCEAGFLNVPKIKGTHTAMKSGMLAAEAIAEALSGSRPAT
HCCCCHHHCCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCC
LDAFPEKVRASWLWPELQAVRNIRPGFAKFGMWGGLINAAFETYVTRGKSPWTLRNHADN
HHHCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCC
TALKPARDATPIAYPKPDGALTFDRLSSVFISNTNHEENQPAHLTLLDPAKAISVNWAEY
CCCCCCCCCCCCCCCCCCCCEEHHHHHHHEEECCCCCCCCCCEEEEECCCCEEEECHHHH
RSPETRYCPAGVYEIVGAEAGDPKLQINAQNCVHCKTCDIKDPTQNINWVVPEGAGGPAY
CCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCEEEECCCCCCCC
PGGM
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]