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The map label for this gene is dapB

Identifier: 148260063

GI number: 148260063

Start: 1176276

End: 1177019

Strand: Reverse

Name: dapB

Synonym: Acry_1055

Alternate gene names: 148260063

Gene position: 1177019-1176276 (Counterclockwise)

Preceding gene: 148260064

Following gene: 148260062

Centisome position: 34.73

GC content: 73.25

Gene sequence:

>744_bases
ATGAACGGAGCAGACCTGCGGATCGGCATTGCCGGCATCACCGGCCGGATGGGCAAGCTGCTGGCCGAGGCCGTGCCGCT
GGCCGGCGCCACGCTGGCCGGCGGCATCGGCCGCGACGGTGACCTCGCCGCCCTCGCGCGCGAAAGCGATGTGGTGATCG
ACTTCACCGTGGCCGCCACGGTCAGCCGCCATGCCGGCATCCTCGCCGCAGCCGGCACGCCCTGGGTGCTCGGCACCACC
GGATTCGATCCGGCCGCCGAGGCCGACATCGCCGATGCGGCCGCGCGGATTCCGGTTTTTCAGGCGGCGAATTTCGCGCC
GGGCGTGAACCTGGTGATCGCGCTGGCCGAGCGCCTCGGCGCCACGCTCGCCGCCGAGACCCACGACGCCGAAATCCTCG
AGATGCACCACCGCCAGAAGATCGACGCGCCCTCCGGCACCGCGCTGGCGATCGGTGCTGCGGTGGCGCGGGGCAGGGGC
GTCGACCTTGCGGCGGTGAAGGACTCCGGGCGCGATGGCCATACCGGCAAGCGCGAGACCGGCGCCATCGGCTTTGCCGC
CCTGCGCGGCGGGCAGATCGTCGGCAGCCACAGCGCGATCTTCACCAGCGCCGTCGAGCAGATCACGCTCACCCACCACG
CGCTCGACCGGCGGATTTTCGCCGAAGGGGCGGTCCGCGCCGCGCTGTGGCTGGCCGGCCGCGCGCCCGGGCGCTACGGC
ATGCGCGACCTGCTCGGCCTGTAG

Upstream 100 bases:

>100_bases
GACGCTGGTGGACATGGCCAAGACCCTCGATCGTCCCTGACCGGCCCGACCCGTGCCGCCGATTTGCAAAATCCCGCCAT
TGGCCCGATAGGCAGACGCC

Downstream 100 bases:

>100_bases
CCGCGCCGCCCCTTGTCTTGACCCCCGGGCGCGATTGCGCCATGCCCCGGCACGCTCCGGCATTCGGCCGGCGCCGCCGC
CCGGCCCGGGCACGACGTCT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MNGADLRIGIAGITGRMGKLLAEAVPLAGATLAGGIGRDGDLAALARESDVVIDFTVAATVSRHAGILAAAGTPWVLGTT
GFDPAAEADIADAAARIPVFQAANFAPGVNLVIALAERLGATLAAETHDAEILEMHHRQKIDAPSGTALAIGAAVARGRG
VDLAAVKDSGRDGHTGKRETGAIGFAALRGGQIVGSHSAIFTSAVEQITLTHHALDRRIFAEGAVRAALWLAGRAPGRYG
MRDLLGL

Sequences:

>Translated_247_residues
MNGADLRIGIAGITGRMGKLLAEAVPLAGATLAGGIGRDGDLAALARESDVVIDFTVAATVSRHAGILAAAGTPWVLGTT
GFDPAAEADIADAAARIPVFQAANFAPGVNLVIALAERLGATLAAETHDAEILEMHHRQKIDAPSGTALAIGAAVARGRG
VDLAAVKDSGRDGHTGKRETGAIGFAALRGGQIVGSHSAIFTSAVEQITLTHHALDRRIFAEGAVRAALWLAGRAPGRYG
MRDLLGL
>Mature_247_residues
MNGADLRIGIAGITGRMGKLLAEAVPLAGATLAGGIGRDGDLAALARESDVVIDFTVAATVSRHAGILAAAGTPWVLGTT
GFDPAAEADIADAAARIPVFQAANFAPGVNLVIALAERLGATLAAETHDAEILEMHHRQKIDAPSGTALAIGAAVARGRG
VDLAAVKDSGRDGHTGKRETGAIGFAALRGGQIVGSHSAIFTSAVEQITLTHHALDRRIFAEGAVRAALWLAGRAPGRYG
MRDLLGL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=271, Percent_Identity=42.0664206642066, Blast_Score=177, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_ACICJ (A5FXD9)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001234190.1
- ProteinModelPortal:   A5FXD9
- SMR:   A5FXD9
- STRING:   A5FXD9
- GeneID:   5162498
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_1055
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   ACRY349163:ACRY_1055-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 25070; Mature: 25070

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGADLRIGIAGITGRMGKLLAEAVPLAGATLAGGIGRDGDLAALARESDVVIDFTVAAT
CCCCEEEEEEECCCHHHHHHHHHHCCCCCCHHCCCCCCCCCEEEEECCCCEEEEEEHHHH
VSRHAGILAAAGTPWVLGTTGFDPAAEADIADAAARIPVFQAANFAPGVNLVIALAERLG
HHHCCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHC
ATLAAETHDAEILEMHHRQKIDAPSGTALAIGAAVARGRGVDLAAVKDSGRDGHTGKRET
CEEECCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHCCCCCEEEEECCCCCCCCCCCCCC
GAIGFAALRGGQIVGSHSAIFTSAVEQITLTHHALDRRIFAEGAVRAALWLAGRAPGRYG
CCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MRDLLGL
HHHHHCC
>Mature Secondary Structure
MNGADLRIGIAGITGRMGKLLAEAVPLAGATLAGGIGRDGDLAALARESDVVIDFTVAAT
CCCCEEEEEEECCCHHHHHHHHHHCCCCCCHHCCCCCCCCCEEEEECCCCEEEEEEHHHH
VSRHAGILAAAGTPWVLGTTGFDPAAEADIADAAARIPVFQAANFAPGVNLVIALAERLG
HHHCCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHC
ATLAAETHDAEILEMHHRQKIDAPSGTALAIGAAVARGRGVDLAAVKDSGRDGHTGKRET
CEEECCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHCCCCCEEEEECCCCCCCCCCCCCC
GAIGFAALRGGQIVGSHSAIFTSAVEQITLTHHALDRRIFAEGAVRAALWLAGRAPGRYG
CCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MRDLLGL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA