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The map label for this gene is betC [H]

Identifier: 148260014

GI number: 148260014

Start: 1114913

End: 1116469

Strand: Reverse

Name: betC [H]

Synonym: Acry_1005

Alternate gene names: 148260014

Gene position: 1116469-1114913 (Counterclockwise)

Preceding gene: 148260016

Following gene: 148260013

Centisome position: 32.94

GC content: 70.2

Gene sequence:

>1557_bases
ATGATGCCTGGGGTTGATGGCAACGGAGCAGACAAGGCGGCGGACGGGCGGCCCAATATCCTGATCGTGATGGCCGACCA
GCTCGGCGCGCGGGCGCTGCCGGCCTATGGCAACCAGGTCGCGCTGACGCCCAATATCGACGCGCTCGCCGCCGGCGGGG
TGGTGTTCGACAACGCCTATTGCAACAGCCCGCTCTGCGGCCCCTCGCGCTACGTGTTCATGAGCGGGCAGCTGCCCTCG
GCGATCGGCGCCTTCGACAACGCGGCCGAGTTTCCGGCGATGCTGCCGAGCTTCGCGCACCACATGCGCGCCGCCGGATA
CCGCACGATCCTGTCCGGCAAGATGCATTTCTGCGGGCCGGACCAGATGCACGGATTCGAGGAGCGGCTGACCACCGACA
TCTACCCGGCCGATTTCGGCTGGACGCCGGACTGGACCGATTTCGCGACGCGGCCGAGCTGGTACCACGACATGAGCTCG
GTGCGCGAGGCGGGGCTGTGCGTGCGGACCAACCAGATGGACTATGACGACGAGGTGGTGTTCGCGGCGCGGCAGAAGCT
GTTCGACCTCGCGCGCGATGACGACGGGCGGCCGTTCTGCATGGTGGTGTCGCTGACGCATCCGCACGATCCCTTCGCGA
TGACGGAGGAATACTGGAACCTCTACGACCACGACGCGATCGACATGCCGCGGGTGCGGACGGCGCCGGCTTCGATGGAC
CCGCATTCGCTGCGGCTGCGCCACGTGTCGAACATGGACAACGAGCCGGTGACCGAGGCGCAGGTGCGCAACGCGCGGCA
CGCCTATTACGCGGCGATCTCCTTCGTCGACCGCCAGCTCGGCCGGCTGCGCGAGACGGTCGAGGCGTGCGGGCTCGCGG
CGCGGACGGTGACGGTGATGACCGCCGATCACGGCGAGCTGCTCGGCGAGCACGGGCTCTGGTACAAGATGAGCTTCTTC
GAGGACGCGTGCCGGATTCCGCTGATCGTGCATGCGCCGGGGCGGTTCGCGCCGGCGCGGGTGGGGGCGGCGGTGTCCTC
GGTCGACATGCTGCCGACGCTGGTCGGGCTCGGCGGCGGGAGGATCCCGGCGGGGCTCGCCTGCGACGGGACCTCGCTGC
TCGGCCATCTCGAAGGGCGCGGCGGGCATGACGGCGCGTTCGGCGAATATCTCGCCGAGGGGGCGATCGCGCCGATCGTG
ATGATCCGGCGCGGGCGGCACAAGTTCATCCATTGCCCGGCCGATCCGGACCAGCTCTTCGACCTCGAGGCCGATCCGGA
CGAGCGGGCGAACCTCGCGGCGGCGCCGGAGCACGCGGCGCTGGTGGCCGCGTTCCGCGCCGAGGTGGCGGCGCGCTGGG
ACCTCGACGCGGTGCATCGCGCGGTGCTGGCGAGCCAGGCGCGGCGGCGCTTCATCGACGCGGCGCTGCGGCAGGGGCGG
CGGAAGTCGTGGGATTTCCAGCCCTTCGTCGATGCCTCGGAACAGTACATGCGCAACCACATGCGGCTCGGCGACCTCGA
GAAGCGGGCGCGGTTTCCCCGGCCGGCGGGGGACTGA

Upstream 100 bases:

>100_bases
TGCTGATGGGTTCCATTCATCGATTCGGTCTTCAAGCGGGCCCGGTTTCAAGGCAGCGTGCCGCCGGATCGATATTGGAC
GCAAGGGGAGATGGCGAGAG

Downstream 100 bases:

>100_bases
CCCGCCGGCGCGATGCGGCGCGATGCGGGATGCATGATTTCCGTATCGCGATCCGCGCGAGTGTGGTGATATGCGGTTCC
GCCGCATGGCTCGTATGCGG

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MMPGVDGNGADKAADGRPNILIVMADQLGARALPAYGNQVALTPNIDALAAGGVVFDNAYCNSPLCGPSRYVFMSGQLPS
AIGAFDNAAEFPAMLPSFAHHMRAAGYRTILSGKMHFCGPDQMHGFEERLTTDIYPADFGWTPDWTDFATRPSWYHDMSS
VREAGLCVRTNQMDYDDEVVFAARQKLFDLARDDDGRPFCMVVSLTHPHDPFAMTEEYWNLYDHDAIDMPRVRTAPASMD
PHSLRLRHVSNMDNEPVTEAQVRNARHAYYAAISFVDRQLGRLRETVEACGLAARTVTVMTADHGELLGEHGLWYKMSFF
EDACRIPLIVHAPGRFAPARVGAAVSSVDMLPTLVGLGGGRIPAGLACDGTSLLGHLEGRGGHDGAFGEYLAEGAIAPIV
MIRRGRHKFIHCPADPDQLFDLEADPDERANLAAAPEHAALVAAFRAEVAARWDLDAVHRAVLASQARRRFIDAALRQGR
RKSWDFQPFVDASEQYMRNHMRLGDLEKRARFPRPAGD

Sequences:

>Translated_518_residues
MMPGVDGNGADKAADGRPNILIVMADQLGARALPAYGNQVALTPNIDALAAGGVVFDNAYCNSPLCGPSRYVFMSGQLPS
AIGAFDNAAEFPAMLPSFAHHMRAAGYRTILSGKMHFCGPDQMHGFEERLTTDIYPADFGWTPDWTDFATRPSWYHDMSS
VREAGLCVRTNQMDYDDEVVFAARQKLFDLARDDDGRPFCMVVSLTHPHDPFAMTEEYWNLYDHDAIDMPRVRTAPASMD
PHSLRLRHVSNMDNEPVTEAQVRNARHAYYAAISFVDRQLGRLRETVEACGLAARTVTVMTADHGELLGEHGLWYKMSFF
EDACRIPLIVHAPGRFAPARVGAAVSSVDMLPTLVGLGGGRIPAGLACDGTSLLGHLEGRGGHDGAFGEYLAEGAIAPIV
MIRRGRHKFIHCPADPDQLFDLEADPDERANLAAAPEHAALVAAFRAEVAARWDLDAVHRAVLASQARRRFIDAALRQGR
RKSWDFQPFVDASEQYMRNHMRLGDLEKRARFPRPAGD
>Mature_518_residues
MMPGVDGNGADKAADGRPNILIVMADQLGARALPAYGNQVALTPNIDALAAGGVVFDNAYCNSPLCGPSRYVFMSGQLPS
AIGAFDNAAEFPAMLPSFAHHMRAAGYRTILSGKMHFCGPDQMHGFEERLTTDIYPADFGWTPDWTDFATRPSWYHDMSS
VREAGLCVRTNQMDYDDEVVFAARQKLFDLARDDDGRPFCMVVSLTHPHDPFAMTEEYWNLYDHDAIDMPRVRTAPASMD
PHSLRLRHVSNMDNEPVTEAQVRNARHAYYAAISFVDRQLGRLRETVEACGLAARTVTVMTADHGELLGEHGLWYKMSFF
EDACRIPLIVHAPGRFAPARVGAAVSSVDMLPTLVGLGGGRIPAGLACDGTSLLGHLEGRGGHDGAFGEYLAEGAIAPIV
MIRRGRHKFIHCPADPDQLFDLEADPDERANLAAAPEHAALVAAFRAEVAARWDLDAVHRAVLASQARRRFIDAALRQGR
RKSWDFQPFVDASEQYMRNHMRLGDLEKRARFPRPAGD

Specific function: Converts choline-O-sulfate into choline [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI39930577, Length=530, Percent_Identity=25.8490566037736, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI4557659, Length=422, Percent_Identity=26.7772511848341, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI71852584, Length=436, Percent_Identity=27.7522935779816, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI262118210, Length=228, Percent_Identity=29.8245614035088, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI31742482, Length=522, Percent_Identity=25.095785440613, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI146229331, Length=458, Percent_Identity=25.1091703056769, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI146229329, Length=458, Percent_Identity=25.1091703056769, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI6005990, Length=458, Percent_Identity=25.1091703056769, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI146229324, Length=458, Percent_Identity=25.1091703056769, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4503899, Length=408, Percent_Identity=26.2254901960784, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI53831991, Length=139, Percent_Identity=39.568345323741, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI58743319, Length=437, Percent_Identity=24.2562929061785, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4504061, Length=485, Percent_Identity=21.8556701030928, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI157266309, Length=121, Percent_Identity=33.8842975206612, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI71852586, Length=111, Percent_Identity=39.6396396396396, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1790112, Length=432, Percent_Identity=29.1666666666667, Blast_Score=129, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24656835, Length=434, Percent_Identity=27.4193548387097, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24647401, Length=391, Percent_Identity=24.0409207161125, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281366397, Length=430, Percent_Identity=24.1860465116279, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281366395, Length=430, Percent_Identity=24.1860465116279, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666163, Length=430, Percent_Identity=24.1860465116279, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR017785
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.6 [H]

Molecular weight: Translated: 57033; Mature: 57033

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPGVDGNGADKAADGRPNILIVMADQLGARALPAYGNQVALTPNIDALAAGGVVFDNAY
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCHHHCCCCEEECCCC
CNSPLCGPSRYVFMSGQLPSAIGAFDNAAEFPAMLPSFAHHMRAAGYRTILSGKMHFCGP
CCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCC
DQMHGFEERLTTDIYPADFGWTPDWTDFATRPSWYHDMSSVREAGLCVRTNQMDYDDEVV
HHHCCHHHHHHCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHCCCEEECCCCCCCHHHH
FAARQKLFDLARDDDGRPFCMVVSLTHPHDPFAMTEEYWNLYDHDAIDMPRVRTAPASMD
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PHSLRLRHVSNMDNEPVTEAQVRNARHAYYAAISFVDRQLGRLRETVEACGLAARTVTVM
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
TADHGELLGEHGLWYKMSFFEDACRIPLIVHAPGRFAPARVGAAVSSVDMLPTLVGLGGG
ECCCHHHHCCCCCEEEEHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
RIPAGLACDGTSLLGHLEGRGGHDGAFGEYLAEGAIAPIVMIRRGRHKFIHCPADPDQLF
CCCCCEEECCHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHEECCCCCEEECCCCHHHEE
DLEADPDERANLAAAPEHAALVAAFRAEVAARWDLDAVHRAVLASQARRRFIDAALRQGR
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
RKSWDFQPFVDASEQYMRNHMRLGDLEKRARFPRPAGD
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MMPGVDGNGADKAADGRPNILIVMADQLGARALPAYGNQVALTPNIDALAAGGVVFDNAY
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCHHHCCCCEEECCCC
CNSPLCGPSRYVFMSGQLPSAIGAFDNAAEFPAMLPSFAHHMRAAGYRTILSGKMHFCGP
CCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCC
DQMHGFEERLTTDIYPADFGWTPDWTDFATRPSWYHDMSSVREAGLCVRTNQMDYDDEVV
HHHCCHHHHHHCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHCCCEEECCCCCCCHHHH
FAARQKLFDLARDDDGRPFCMVVSLTHPHDPFAMTEEYWNLYDHDAIDMPRVRTAPASMD
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PHSLRLRHVSNMDNEPVTEAQVRNARHAYYAAISFVDRQLGRLRETVEACGLAARTVTVM
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
TADHGELLGEHGLWYKMSFFEDACRIPLIVHAPGRFAPARVGAAVSSVDMLPTLVGLGGG
ECCCHHHHCCCCCEEEEHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
RIPAGLACDGTSLLGHLEGRGGHDGAFGEYLAEGAIAPIVMIRRGRHKFIHCPADPDQLF
CCCCCEEECCHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHEECCCCCEEECCCCHHHEE
DLEADPDERANLAAAPEHAALVAAFRAEVAARWDLDAVHRAVLASQARRRFIDAALRQGR
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
RKSWDFQPFVDASEQYMRNHMRLGDLEKRARFPRPAGD
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141699; 11481430; 9736747 [H]