Click here to switch to the map view.

The map label for this gene is codA [H]

Identifier: 148259839

GI number: 148259839

Start: 917514

End: 918797

Strand: Reverse

Name: codA [H]

Synonym: Acry_0828

Alternate gene names: 148259839

Gene position: 918797-917514 (Counterclockwise)

Preceding gene: 148259840

Following gene: 148259825

Centisome position: 27.11

GC content: 68.85

Gene sequence:

>1284_bases
GTGACGGGCGACCTGCTCATCCGCAACGCGGCGCTGCCGGATGGGCGGCGCGGGGTCGACATCCTGATCCGCGGCGGCGT
GATCGAGACGGTCGGCCCCGGTCTTCCAGAGGCGGCCGCGCCGGCGGTGATCGACGCGGCGGGGGATCTGGTCGCGCCAC
CCTTCGTCGATTCGCATCTGCACCTCGATTCGACGCTGTCGCTCGGGCTGCCGCGGCTGAACCGCAGCGGCACGCTGCTG
GAGGGCATCGCCCTCTGGGGCGAGCTCAAGCCGGACCTGACCGTGGAGGCCATCCATGCGCGGGCGAAGCGGCTCTGCAC
CTGGTCGATCGCGCAGGGGATCGGGGCGATCCGCTCGCATGTCGATATCTGCGACGACCGTCTGCTCGCGGTGGAGGCGC
TGACAGCGCTGCGGGCGGAGATGGCGCCGTGGATCACCATCCAGCTCGTCGCCTTTCCGCAGGATGGCTGGCTACGCTAT
CCGCGTTCGGCCGAGAACCTGCGCCGGGCGATGGCGATGGGGATCGACGTGATCGGCGGGATTCCGCATTTCGAGCGGAC
CATGGCGGACGGGGCGGAGAGCGTGCGCCAGCTGATGGCCATCGCCGCCGAGGCCGGGATGATGGTCGACATGCATTGCG
ACGAGAGCGACGATCCGCTGTCGCGCCATATCGAGACGCTGGCGGCGGAGACCGTGCGGCACGGGATGCAGGGGCGCGTT
GCCGGATCGCATCTCACCTCGATGCACTCGATGGATAATTATTACGCGAGCAAGCTGATTCCGCTGATCGCCGAGGCCGG
GGTTTCCGCGATCGCCAATCCGCTGATCAATATCACGTTGCAGGGGCGGCACGACACCTATCCGAAGCGGCGGGGCATGA
CGCGGGTGCCGGAGCTGATGGCGGCCGGGGTGAATGTCGCCTTCGGGCATGATTGCGTGATGGATCCGTGGTATCCGCTC
GGCACGCACGACATGCTGGAGGTGGCATCGATGGGACTTCACGTCGCGCAGATGACCGGCGTGGACGCGATGCGTTCCTG
TTTCGATGCCGTTACGGTAAACGCGGCGCGGGCGATGGGGCTGGAGGGTTACGGCATCGCCCCCGGATGCCGGGGCGATC
TGGTGCTGCTCGATGCCGGCGATCCGATCGAGGCGATCCGCACCCGCGCCGCGCGGCGCGCGGTGATTCGCGGCGGGATC
GCGATCGCCGAATCGCCGGCGCGCGTCAGCCGGCTTCGCCTCGGCGACGAGGCGATGGAGGTTCGCTTCCGCGCGGCGGG
GTGA

Upstream 100 bases:

>100_bases
CCGATTCGATCGAGTTCTGGCAGGACCGGGACTTCCGCCTGCACGACCGCGCGGTGTTCACCCGCACCGGCGACGCCTGG
TCGGCGACGAGACTGTTCCC

Downstream 100 bases:

>100_bases
GGCGCGGCGGCGTCAGGCAAGGGCCATCCCCCCTGCCCGCAGCGCCGCGATATTCGCCGCATAGGCCGCCCTGCCGCCGC
GAAAGACCGAGGAGCCGGCG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MTGDLLIRNAALPDGRRGVDILIRGGVIETVGPGLPEAAAPAVIDAAGDLVAPPFVDSHLHLDSTLSLGLPRLNRSGTLL
EGIALWGELKPDLTVEAIHARAKRLCTWSIAQGIGAIRSHVDICDDRLLAVEALTALRAEMAPWITIQLVAFPQDGWLRY
PRSAENLRRAMAMGIDVIGGIPHFERTMADGAESVRQLMAIAAEAGMMVDMHCDESDDPLSRHIETLAAETVRHGMQGRV
AGSHLTSMHSMDNYYASKLIPLIAEAGVSAIANPLINITLQGRHDTYPKRRGMTRVPELMAAGVNVAFGHDCVMDPWYPL
GTHDMLEVASMGLHVAQMTGVDAMRSCFDAVTVNAARAMGLEGYGIAPGCRGDLVLLDAGDPIEAIRTRAARRAVIRGGI
AIAESPARVSRLRLGDEAMEVRFRAAG

Sequences:

>Translated_427_residues
MTGDLLIRNAALPDGRRGVDILIRGGVIETVGPGLPEAAAPAVIDAAGDLVAPPFVDSHLHLDSTLSLGLPRLNRSGTLL
EGIALWGELKPDLTVEAIHARAKRLCTWSIAQGIGAIRSHVDICDDRLLAVEALTALRAEMAPWITIQLVAFPQDGWLRY
PRSAENLRRAMAMGIDVIGGIPHFERTMADGAESVRQLMAIAAEAGMMVDMHCDESDDPLSRHIETLAAETVRHGMQGRV
AGSHLTSMHSMDNYYASKLIPLIAEAGVSAIANPLINITLQGRHDTYPKRRGMTRVPELMAAGVNVAFGHDCVMDPWYPL
GTHDMLEVASMGLHVAQMTGVDAMRSCFDAVTVNAARAMGLEGYGIAPGCRGDLVLLDAGDPIEAIRTRAARRAVIRGGI
AIAESPARVSRLRLGDEAMEVRFRAAG
>Mature_426_residues
TGDLLIRNAALPDGRRGVDILIRGGVIETVGPGLPEAAAPAVIDAAGDLVAPPFVDSHLHLDSTLSLGLPRLNRSGTLLE
GIALWGELKPDLTVEAIHARAKRLCTWSIAQGIGAIRSHVDICDDRLLAVEALTALRAEMAPWITIQLVAFPQDGWLRYP
RSAENLRRAMAMGIDVIGGIPHFERTMADGAESVRQLMAIAAEAGMMVDMHCDESDDPLSRHIETLAAETVRHGMQGRVA
GSHLTSMHSMDNYYASKLIPLIAEAGVSAIANPLINITLQGRHDTYPKRRGMTRVPELMAAGVNVAFGHDCVMDPWYPLG
THDMLEVASMGLHVAQMTGVDAMRSCFDAVTVNAARAMGLEGYGIAPGCRGDLVLLDAGDPIEAIRTRAARRAVIRGGIA
IAESPARVSRLRLGDEAMEVRFRAAG

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=380, Percent_Identity=46.0526315789474, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1786517, Length=380, Percent_Identity=28.6842105263158, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 45723; Mature: 45592

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDLLIRNAALPDGRRGVDILIRGGVIETVGPGLPEAAAPAVIDAAGDLVAPPFVDSHL
CCCCEEEEECCCCCCCCCCEEEEECCCHHHCCCCCCCHHCCHHEECCCCCCCCCCCCCCC
HLDSTLSLGLPRLNRSGTLLEGIALWGELKPDLTVEAIHARAKRLCTWSIAQGIGAIRSH
CCCCHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDICDDRLLAVEALTALRAEMAPWITIQLVAFPQDGWLRYPRSAENLRRAMAMGIDVIGG
HHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHCC
IPHFERTMADGAESVRQLMAIAAEAGMMVDMHCDESDDPLSRHIETLAAETVRHGMQGRV
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
AGSHLTSMHSMDNYYASKLIPLIAEAGVSAIANPLINITLQGRHDTYPKRRGMTRVPELM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHH
AAGVNVAFGHDCVMDPWYPLGTHDMLEVASMGLHVAQMTGVDAMRSCFDAVTVNAARAMG
HCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHCC
LEGYGIAPGCRGDLVLLDAGDPIEAIRTRAARRAVIRGGIAIAESPARVSRLRLGDEAME
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCHHHE
VRFRAAG
EEEEECC
>Mature Secondary Structure 
TGDLLIRNAALPDGRRGVDILIRGGVIETVGPGLPEAAAPAVIDAAGDLVAPPFVDSHL
CCCEEEEECCCCCCCCCCEEEEECCCHHHCCCCCCCHHCCHHEECCCCCCCCCCCCCCC
HLDSTLSLGLPRLNRSGTLLEGIALWGELKPDLTVEAIHARAKRLCTWSIAQGIGAIRSH
CCCCHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDICDDRLLAVEALTALRAEMAPWITIQLVAFPQDGWLRYPRSAENLRRAMAMGIDVIGG
HHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHCC
IPHFERTMADGAESVRQLMAIAAEAGMMVDMHCDESDDPLSRHIETLAAETVRHGMQGRV
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
AGSHLTSMHSMDNYYASKLIPLIAEAGVSAIANPLINITLQGRHDTYPKRRGMTRVPELM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHH
AAGVNVAFGHDCVMDPWYPLGTHDMLEVASMGLHVAQMTGVDAMRSCFDAVTVNAARAMG
HCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHCC
LEGYGIAPGCRGDLVLLDAGDPIEAIRTRAARRAVIRGGIAIAESPARVSRLRLGDEAME
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHCCCHHHE
VRFRAAG
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]