Click here to switch to the map view.

The map label for this gene is ycgM [C]

Identifier: 148259432

GI number: 148259432

Start: 469280

End: 469963

Strand: Reverse

Name: ycgM [C]

Synonym: Acry_0415

Alternate gene names: 148259432

Gene position: 469963-469280 (Counterclockwise)

Preceding gene: 148259433

Following gene: 148259431

Centisome position: 13.87

GC content: 62.87

Gene sequence:

>684_bases
ATGTCCGAATTCGTGATCGCACCGCCGGCAATACCGGCTGTTCCCGTTGCGGGCGGTGGGCTCTTCCCGGTCCGACGCAT
CTTCTGTGTCGGCCGCAACTACGCGGCGCACACGCGGGAAATGGGGGGCGATCCGAATCGCGAGCCGCCGTTCTTCTTCA
CCAAACCCGCCGATGCGATTGCGCTGGGCGACAGCGTCCCCTTCCCTTCGGCAACGCAGAACCTTCATCACGAGATGGAA
CTCGTCGTGGCGCTGGGCGCAGGCGGCCGGGATATCCCGTCCGACGCGGCGCTGGCCCATATCTATGGCTATGCGGCCGG
CGTAGATCTGACCCGCCGGGATCTGCAGGACGAAGCAAAGTCGCTTCGCCGTCCGTGGGACATGAGCAAGGGTTTCGATC
TCTCTGCGCCGATCAGCCTCATTGTTCCGGCCGCACAAATTGGTCATCCTGCTGCTGGCCGCATCTCCCTCGCGGTGAAT
GGCGAGCAGCGCCAAAACGGCGATCTTTCCGACATGATCTGGCCGGTCGCCGACATTATCTCGTTCCTTTCGTCCCTCGT
GGAACTGAAGCCGGGCGATCTGATCTATACCGGCACGCCCGATGGCGTCGGCCAGATCCAACCTGGCGACCGCGTTTACG
GCGTCATTGATGGCGTCGGCGAACTGGAATTCACCCTCGCATGA

Upstream 100 bases:

>100_bases
GATTTCGAACATGATGCGGCATCCCGCCGCATTTTCGAGAGCTTCGGGGCCGCCGTGAACAAGGCGGTCTGATCAGTCAC
AATAAAGGCAGGAACAGAAT

Downstream 100 bases:

>100_bases
CCGCTCTGACCGTCGCGACCTGGAACATAAATTCGGTTCGACTCCGTCGGGATCTGCTGCACAGTCTCATGGATCAGGCC
GCGCCCGATATCGTTTGCCT

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSEFVIAPPAIPAVPVAGGGLFPVRRIFCVGRNYAAHTREMGGDPNREPPFFFTKPADAIALGDSVPFPSATQNLHHEME
LVVALGAGGRDIPSDAALAHIYGYAAGVDLTRRDLQDEAKSLRRPWDMSKGFDLSAPISLIVPAAQIGHPAAGRISLAVN
GEQRQNGDLSDMIWPVADIISFLSSLVELKPGDLIYTGTPDGVGQIQPGDRVYGVIDGVGELEFTLA

Sequences:

>Translated_227_residues
MSEFVIAPPAIPAVPVAGGGLFPVRRIFCVGRNYAAHTREMGGDPNREPPFFFTKPADAIALGDSVPFPSATQNLHHEME
LVVALGAGGRDIPSDAALAHIYGYAAGVDLTRRDLQDEAKSLRRPWDMSKGFDLSAPISLIVPAAQIGHPAAGRISLAVN
GEQRQNGDLSDMIWPVADIISFLSSLVELKPGDLIYTGTPDGVGQIQPGDRVYGVIDGVGELEFTLA
>Mature_226_residues
SEFVIAPPAIPAVPVAGGGLFPVRRIFCVGRNYAAHTREMGGDPNREPPFFFTKPADAIALGDSVPFPSATQNLHHEMEL
VVALGAGGRDIPSDAALAHIYGYAAGVDLTRRDLQDEAKSLRRPWDMSKGFDLSAPISLIVPAAQIGHPAAGRISLAVNG
EQRQNGDLSDMIWPVADIISFLSSLVELKPGDLIYTGTPDGVGQIQPGDRVYGVIDGVGELEFTLA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=203, Percent_Identity=42.8571428571429, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=43.8775510204082, Blast_Score=167, Evalue=5e-42,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=43.8775510204082, Blast_Score=167, Evalue=6e-42,
Organism=Homo sapiens, GI156231349, Length=203, Percent_Identity=31.5270935960591, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI40786394, Length=203, Percent_Identity=30.5418719211823, Blast_Score=107, Evalue=6e-24,
Organism=Escherichia coli, GI1787428, Length=199, Percent_Identity=42.713567839196, Blast_Score=163, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=34.1836734693878, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324161, Length=237, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28571789, Length=200, Percent_Identity=30, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28572127, Length=206, Percent_Identity=33.0097087378641, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24663695, Length=208, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24084; Mature: 23952

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFVIAPPAIPAVPVAGGGLFPVRRIFCVGRNYAAHTREMGGDPNREPPFFFTKPADAI
CCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCEE
ALGDSVPFPSATQNLHHEMELVVALGAGGRDIPSDAALAHIYGYAAGVDLTRRDLQDEAK
EECCCCCCCCHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
SLRRPWDMSKGFDLSAPISLIVPAAQIGHPAAGRISLAVNGEQRQNGDLSDMIWPVADII
HHCCCCCCCCCCCCCCCHHEEECHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
SFLSSLVELKPGDLIYTGTPDGVGQIQPGDRVYGVIDGVGELEFTLA
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEC
>Mature Secondary Structure 
SEFVIAPPAIPAVPVAGGGLFPVRRIFCVGRNYAAHTREMGGDPNREPPFFFTKPADAI
CCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCEE
ALGDSVPFPSATQNLHHEMELVVALGAGGRDIPSDAALAHIYGYAAGVDLTRRDLQDEAK
EECCCCCCCCHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
SLRRPWDMSKGFDLSAPISLIVPAAQIGHPAAGRISLAVNGEQRQNGDLSDMIWPVADII
HHCCCCCCCCCCCCCCCHHEEECHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
SFLSSLVELKPGDLIYTGTPDGVGQIQPGDRVYGVIDGVGELEFTLA
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]