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The map label for this gene is hypB [H]

Identifier: 148259349

GI number: 148259349

Start: 381787

End: 382671

Strand: Reverse

Name: hypB [H]

Synonym: Acry_0330

Alternate gene names: 148259349

Gene position: 382671-381787 (Counterclockwise)

Preceding gene: 148259350

Following gene: 148259338

Centisome position: 11.29

GC content: 69.94

Gene sequence:

>885_bases
ATGTGCGGCATATGCGGCTGCGGCGATACCGGGGAACACCATCATGAGCATGAGCATGAGCATGGGCATGGGCATGGGCA
CGGGCACGACCACGGGCATGATCATGGCCACGCGGCGGAGCACGCGCACGCGGCGGGGCTGGCGCCGGCGCGGATGGTGC
GGGTGGAGCAGGACATCATGGCGGCGAACCAGCGCCATGCCGATGCCAACCGGACGTATTTCGCCGAGCGGGGCATTTTC
GTCGTCAACCTCGTCTCCAGCCCCGGCTCGGGCAAGACCTCGCTGCTGGTGCGGACGGTCGCGGCGCTGAAGGCGGAGAT
GCCGGTCGCGGTGATCGAGGGCGACCAGCAGACGGAGTTCGACGCCGAGCGGATCCGCGCGGCGGGGGCGCCGGCCTGGC
AGATCAATACCGGCAAGGCGTGCCATCTCGACGCGCACATGGTCGGCCACGCGCTGGAGCACCTGCCGGCGCTGGAGGGC
GGGATCCTGTTCATCGAGAATGTCGGCAACCTCGTCTGCCCGGCGGGGTTCGACCTCGGCGAGGCGCACAAGGTCGTCAT
TCTCTCGGTGACCGAGGGCGAGGACAAGCCGCTGAAATATCCGCACATGTTCCACGCCGCCGACCTGATGCTGGTCAACA
AGATCGACCTGCTGCCGCATGTGGCGTGCGACATGGAGCTGATCCTCGCCGGCGCGCTGCGGGTGAATCCGGCCATCGGG
TCGTTCGCGGTCTCGGCGGCGACGGGAGAGGGATTCGGCGCGTGGCTGGACTGGCTGCGCCAGGGGCGCGAGCGGGCGCG
GCGGGCGCAGCACGGGGCGATGCAGGCGCGGCGCGAGGCGTTGCGGCGGGAGCTGGCCTCGATCGACGCGACGCTCGCGG
GCTGA

Upstream 100 bases:

>100_bases
CGCTGCGGCGCTTCGGCGATCCGTGTCCGCATTGCGGCAGCCTGCAATTGCAGGTGCTCGACGGCAAGCAGATCAGGATC
AGGCAGATCGAGGTGACATG

Downstream 100 bases:

>100_bases
TCCCGCTCAGCAGATCCGCGGCAGCGGGTCGGATTCCAGTTCGGGCAGGGTCCGCGCGCCGCCGATGCGGGTGCGCAGGA
GAACCGGGGCATCGGCCGGG

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MCGICGCGDTGEHHHEHEHEHGHGHGHGHDHGHDHGHAAEHAHAAGLAPARMVRVEQDIMAANQRHADANRTYFAERGIF
VVNLVSSPGSGKTSLLVRTVAALKAEMPVAVIEGDQQTEFDAERIRAAGAPAWQINTGKACHLDAHMVGHALEHLPALEG
GILFIENVGNLVCPAGFDLGEAHKVVILSVTEGEDKPLKYPHMFHAADLMLVNKIDLLPHVACDMELILAGALRVNPAIG
SFAVSAATGEGFGAWLDWLRQGRERARRAQHGAMQARREALRRELASIDATLAG

Sequences:

>Translated_294_residues
MCGICGCGDTGEHHHEHEHEHGHGHGHGHDHGHDHGHAAEHAHAAGLAPARMVRVEQDIMAANQRHADANRTYFAERGIF
VVNLVSSPGSGKTSLLVRTVAALKAEMPVAVIEGDQQTEFDAERIRAAGAPAWQINTGKACHLDAHMVGHALEHLPALEG
GILFIENVGNLVCPAGFDLGEAHKVVILSVTEGEDKPLKYPHMFHAADLMLVNKIDLLPHVACDMELILAGALRVNPAIG
SFAVSAATGEGFGAWLDWLRQGRERARRAQHGAMQARREALRRELASIDATLAG
>Mature_294_residues
MCGICGCGDTGEHHHEHEHEHGHGHGHGHDHGHDHGHAAEHAHAAGLAPARMVRVEQDIMAANQRHADANRTYFAERGIF
VVNLVSSPGSGKTSLLVRTVAALKAEMPVAVIEGDQQTEFDAERIRAAGAPAWQINTGKACHLDAHMVGHALEHLPALEG
GILFIENVGNLVCPAGFDLGEAHKVVILSVTEGEDKPLKYPHMFHAADLMLVNKIDLLPHVACDMELILAGALRVNPAIG
SFAVSAATGEGFGAWLDWLRQGRERARRAQHGAMQARREALRRELASIDATLAG

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=290, Percent_Identity=51.3793103448276, Blast_Score=283, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 31558; Mature: 31558

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGICGCGDTGEHHHEHEHEHGHGHGHGHDHGHDHGHAAEHAHAAGLAPARMVRVEQDIM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
AANQRHADANRTYFAERGIFVVNLVSSPGSGKTSLLVRTVAALKAEMPVAVIEGDQQTEF
HHHHCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHH
DAERIRAAGAPAWQINTGKACHLDAHMVGHALEHLPALEGGILFIENVGNLVCPAGFDLG
HHHHHHHCCCCEEEECCCCEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCEECCCCCCCC
EAHKVVILSVTEGEDKPLKYPHMFHAADLMLVNKIDLLPHVACDMELILAGALRVNPAIG
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCC
SFAVSAATGEGFGAWLDWLRQGRERARRAQHGAMQARREALRRELASIDATLAG
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCGICGCGDTGEHHHEHEHEHGHGHGHGHDHGHDHGHAAEHAHAAGLAPARMVRVEQDIM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
AANQRHADANRTYFAERGIFVVNLVSSPGSGKTSLLVRTVAALKAEMPVAVIEGDQQTEF
HHHHCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHH
DAERIRAAGAPAWQINTGKACHLDAHMVGHALEHLPALEGGILFIENVGNLVCPAGFDLG
HHHHHHHCCCCEEEECCCCEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCEECCCCCCCC
EAHKVVILSVTEGEDKPLKYPHMFHAADLMLVNKIDLLPHVACDMELILAGALRVNPAIG
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCC
SFAVSAATGEGFGAWLDWLRQGRERARRAQHGAMQARREALRRELASIDATLAG
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]