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The map label for this gene is etfA [H]

Identifier: 148259167

GI number: 148259167

Start: 167310

End: 168245

Strand: Reverse

Name: etfA [H]

Synonym: Acry_0147

Alternate gene names: 148259167

Gene position: 168245-167310 (Counterclockwise)

Preceding gene: 148259168

Following gene: 148259166

Centisome position: 4.96

GC content: 68.8

Gene sequence:

>936_bases
ATGGCAGAGGTTCTGGTTCTCATCGAGCACGACGGCGCGCATGTGAAGCAGCCGGCGCGCAGCGCGGTTGCGGCGGCGGC
GAAGCTCGGCACGGTGCATGCGCTGGTCGCTGGCGAAAACGTGGGGGGCGCAGCGCAGGAAGCCGCCGCGATCGCCGGGG
TGGACAAGGTGCTGGTCGCGGACAGCAAGGCGCTGGCGCACGCGCTGGCCGAGCCGCTGGCCGACCTGATCGTGAAACTC
GCCGGCAATTACACGCATGTCCTCGCCGCCTCCACCGCGACCGGCAAGAACGTGATGCCCCGCGCCGCAGCCCTGCTCGA
CGTGCAGCCGATCAGCGACATCGCCGGGGTGGTGGATGCCGACACCTTCGTCCGCCCGATCTATGCCGGCAACGCGATGG
CAACGGTGAAATCCGCCGACGCGAAGAAGCTCATCACCGTGCGCGCGGCGAGCTTCGATCCCGCACCGGCCGAAGGCGGA
GCGGCGGCGATCGAGACGATCGAGGTCGGGGTCGACGCCGGTGGTTCGAGCTTCGTCGGCGCCGAGCTTTCGAAGAGCGA
GCGGCCGGAGCTGACGGCGGCGCGGATCGTGGTTTCCGGCGGGCGCGGCATGCAGAACGGCGAGAATTTCGGCAAGCTGC
TCGACCCGATCGCCGACCGGCTGGGGGCCGCGGTGGGCGCCTCGCGTGCGGCGGTCGATGCCGGGTTCGTGCCGAACGAC
TACCAGGTGGGGCAGACCGGCAAGATCGTCGCCCCCGACCTCTACATGGCGGTCGGCATTTCCGGCGCGATCCAGCATCT
CGCGGGCATGAAGGATTCCAAGGTCATCGTCGCGATCAACAAGGACGAGGACGCGCCGATCTTCCAGGTGGCCGATTACG
GCCTGGTGGGCGACCTGTTCACAGTGCTGCCGGAGTTGCAGAAGGAGCTCGGCTGA

Upstream 100 bases:

>100_bases
TGAAGGTGGCCGAGCCGCCGCAGCGCAAGGCCGGGGTCAAGGTCGGCTCGGTGGCCGAACTCGTCGAGAAACTGCGCAAC
GAAGCGAAGGTGATCTGATC

Downstream 100 bases:

>100_bases
GCCCTGCGGGCTTGAGCGACATCAAGGCGCCGGGCGGCCATAAAGGCTAGCCCGGCCTGTGTTTCAGGCGGAAGGAAAAG
TAGATGGAGATCAGGACTCT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MAEVLVLIEHDGAHVKQPARSAVAAAAKLGTVHALVAGENVGGAAQEAAAIAGVDKVLVADSKALAHALAEPLADLIVKL
AGNYTHVLAASTATGKNVMPRAAALLDVQPISDIAGVVDADTFVRPIYAGNAMATVKSADAKKLITVRAASFDPAPAEGG
AAAIETIEVGVDAGGSSFVGAELSKSERPELTAARIVVSGGRGMQNGENFGKLLDPIADRLGAAVGASRAAVDAGFVPND
YQVGQTGKIVAPDLYMAVGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVGDLFTVLPELQKELG

Sequences:

>Translated_311_residues
MAEVLVLIEHDGAHVKQPARSAVAAAAKLGTVHALVAGENVGGAAQEAAAIAGVDKVLVADSKALAHALAEPLADLIVKL
AGNYTHVLAASTATGKNVMPRAAALLDVQPISDIAGVVDADTFVRPIYAGNAMATVKSADAKKLITVRAASFDPAPAEGG
AAAIETIEVGVDAGGSSFVGAELSKSERPELTAARIVVSGGRGMQNGENFGKLLDPIADRLGAAVGASRAAVDAGFVPND
YQVGQTGKIVAPDLYMAVGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVGDLFTVLPELQKELG
>Mature_310_residues
AEVLVLIEHDGAHVKQPARSAVAAAAKLGTVHALVAGENVGGAAQEAAAIAGVDKVLVADSKALAHALAEPLADLIVKLA
GNYTHVLAASTATGKNVMPRAAALLDVQPISDIAGVVDADTFVRPIYAGNAMATVKSADAKKLITVRAASFDPAPAEGGA
AAIETIEVGVDAGGSSFVGAELSKSERPELTAARIVVSGGRGMQNGENFGKLLDPIADRLGAAVGASRAAVDAGFVPNDY
QVGQTGKIVAPDLYMAVGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVGDLFTVLPELQKELG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=309, Percent_Identity=55.9870550161812, Blast_Score=317, Evalue=7e-87,
Organism=Homo sapiens, GI189181759, Length=268, Percent_Identity=59.7014925373134, Blast_Score=303, Evalue=1e-82,
Organism=Escherichia coli, GI1786226, Length=182, Percent_Identity=36.8131868131868, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787990, Length=238, Percent_Identity=31.9327731092437, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082157, Length=184, Percent_Identity=33.1521739130435, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=316, Percent_Identity=55.0632911392405, Blast_Score=310, Evalue=8e-85,
Organism=Saccharomyces cerevisiae, GI6325261, Length=289, Percent_Identity=48.4429065743945, Blast_Score=281, Evalue=1e-76,
Organism=Drosophila melanogaster, GI17136898, Length=310, Percent_Identity=57.0967741935484, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24652801, Length=310, Percent_Identity=57.0967741935484, Blast_Score=323, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31441; Mature: 31310

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLVLIEHDGAHVKQPARSAVAAAAKLGTVHALVAGENVGGAAQEAAAIAGVDKVLVA
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCHHHEEE
DSKALAHALAEPLADLIVKLAGNYTHVLAASTATGKNVMPRAAALLDVQPISDIAGVVDA
CCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHEECCCHHHHHHHHCC
DTFVRPIYAGNAMATVKSADAKKLITVRAASFDPAPAEGGAAAIETIEVGVDAGGSSFVG
HHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCC
AELSKSERPELTAARIVVSGGRGMQNGENFGKLLDPIADRLGAAVGASRAAVDAGFVPND
CCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPDLYMAVGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVGDLF
CEECCCCCEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCHHHHHH
TVLPELQKELG
HHHHHHHHHCC
>Mature Secondary Structure 
AEVLVLIEHDGAHVKQPARSAVAAAAKLGTVHALVAGENVGGAAQEAAAIAGVDKVLVA
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCHHHEEE
DSKALAHALAEPLADLIVKLAGNYTHVLAASTATGKNVMPRAAALLDVQPISDIAGVVDA
CCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHEECCCHHHHHHHHCC
DTFVRPIYAGNAMATVKSADAKKLITVRAASFDPAPAEGGAAAIETIEVGVDAGGSSFVG
HHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCC
AELSKSERPELTAARIVVSGGRGMQNGENFGKLLDPIADRLGAAVGASRAAVDAGFVPND
CCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPDLYMAVGISGAIQHLAGMKDSKVIVAINKDEDAPIFQVADYGLVGDLF
CEECCCCCEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCHHHHHH
TVLPELQKELG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]