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The map label for this gene is thyX [H]

Identifier: 148259066

GI number: 148259066

Start: 44723

End: 45655

Strand: Reverse

Name: thyX [H]

Synonym: Acry_0045

Alternate gene names: 148259066

Gene position: 45655-44723 (Counterclockwise)

Preceding gene: 148259067

Following gene: 148259065

Centisome position: 1.35

GC content: 65.38

Gene sequence:

>933_bases
ATGCCGCTCAGCGATTCCGACCGGACCGAGATCGAGGCCGCGCGCGCCGAAACCACGCCGACCCGCCGCGCCACCGTACC
CACGCTCGAGGCCATGCTTTTCAGCGCGATTCCGGTGCTCGATCACGGTTTTGTCCGCGTCGTCGACTATATGGGCGACG
ATGCCGCCGTCGTGCAGGCGGCACGCGTCTCCTATGGCCGAGGCACCCGCAAAGTCAGCGAGGACGAGGGACTGATCCGC
TACCTCATGCGCCACCGGCATTCCACACCCTTCGAAATGTGCGAGATCAAGCTGCACGTGAAGCTGCCGATCTTCGTCGC
GCGCCAGTGGATCCGCCATCGCACCGCGAACGTGAACGAATATTCCGCGCGCTATTCGGTGATGGACCGCGAATTCTACA
TCCCCTCCCCGGCCAATCTCGCCGCCCAGTCGGCCAGCAACCGGCAAGGTCGGGGAGACCTGCTCGAGGGCGACGAGGCG
TCCGAGGTGCTTGCCATGCTGCGCGCGGATGCCGAGCGGAATTACAATCATTATGAGCGTATGCTGAACGAAGGCGGCGC
CGATCCCTCTCGCCGCGGCCTCGCGCGCGAACTGGCCAGGATGAACCTGACCCTCAACACCTATACCCAGTGGTACTGGA
AGACCGACCTGCACAACCTCTTCCACTTCCTGTCCCTGCGCGCCGATCCCCACGCCCAGTACGAGATCCGCGCCTATGCC
GAGGCAATCCTCGATATCGCCCGCGCCTGGGTTCCGGCCAGTTGCCGCGCCTTCGAGGATTACCGCATGGGGGCCGCGAC
CTTCTCGGCCACGATGCTCGCAGCCCTGCGCCGGATGCTGGCCGGCGAACCCGTCGATCAAGCGCAATCCGGCCTGTCGA
AGCGCGAATGGGCGGAAATGATGGCTGCACTCACCCCGCCCACGCCGGGCTGA

Upstream 100 bases:

>100_bases
CGCGCTCTATATAGGTGAAGGACACCGGCTGTGAAAGATCCTGTTCTTGCCGATGGCGCCGGACGGGCATAGGACGATCG
CTCAACCAGGGACTGCCGTC

Downstream 100 bases:

>100_bases
TCTGCGTACGGTCAAATTTTTCCGAAATATGTCTGCCGGTTGAACTTATGTCCTTGACGAGCGATGCCGCTTTCCCCGCA
ATAGTCAACGTTCGGGCACG

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MPLSDSDRTEIEAARAETTPTRRATVPTLEAMLFSAIPVLDHGFVRVVDYMGDDAAVVQAARVSYGRGTRKVSEDEGLIR
YLMRHRHSTPFEMCEIKLHVKLPIFVARQWIRHRTANVNEYSARYSVMDREFYIPSPANLAAQSASNRQGRGDLLEGDEA
SEVLAMLRADAERNYNHYERMLNEGGADPSRRGLARELARMNLTLNTYTQWYWKTDLHNLFHFLSLRADPHAQYEIRAYA
EAILDIARAWVPASCRAFEDYRMGAATFSATMLAALRRMLAGEPVDQAQSGLSKREWAEMMAALTPPTPG

Sequences:

>Translated_310_residues
MPLSDSDRTEIEAARAETTPTRRATVPTLEAMLFSAIPVLDHGFVRVVDYMGDDAAVVQAARVSYGRGTRKVSEDEGLIR
YLMRHRHSTPFEMCEIKLHVKLPIFVARQWIRHRTANVNEYSARYSVMDREFYIPSPANLAAQSASNRQGRGDLLEGDEA
SEVLAMLRADAERNYNHYERMLNEGGADPSRRGLARELARMNLTLNTYTQWYWKTDLHNLFHFLSLRADPHAQYEIRAYA
EAILDIARAWVPASCRAFEDYRMGAATFSATMLAALRRMLAGEPVDQAQSGLSKREWAEMMAALTPPTPG
>Mature_309_residues
PLSDSDRTEIEAARAETTPTRRATVPTLEAMLFSAIPVLDHGFVRVVDYMGDDAAVVQAARVSYGRGTRKVSEDEGLIRY
LMRHRHSTPFEMCEIKLHVKLPIFVARQWIRHRTANVNEYSARYSVMDREFYIPSPANLAAQSASNRQGRGDLLEGDEAS
EVLAMLRADAERNYNHYERMLNEGGADPSRRGLARELARMNLTLNTYTQWYWKTDLHNLFHFLSLRADPHAQYEIRAYAE
AILDIARAWVPASCRAFEDYRMGAATFSATMLAALRRMLAGEPVDQAQSGLSKREWAEMMAALTPPTPG

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 35101; Mature: 34970

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSDSDRTEIEAARAETTPTRRATVPTLEAMLFSAIPVLDHGFVRVVDYMGDDAAVVQA
CCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ARVSYGRGTRKVSEDEGLIRYLMRHRHSTPFEMCEIKLHVKLPIFVARQWIRHRTANVNE
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHCCCCHH
YSARYSVMDREFYIPSPANLAAQSASNRQGRGDLLEGDEASEVLAMLRADAERNYNHYER
HHHHHHHHCCEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHH
MLNEGGADPSRRGLARELARMNLTLNTYTQWYWKTDLHNLFHFLSLRADPHAQYEIRAYA
HHHCCCCCHHHHHHHHHHHHHCCEEEHHHHHEEHHHHHHHHHHHHHCCCCCCCHHHHHHH
EAILDIARAWVPASCRAFEDYRMGAATFSATMLAALRRMLAGEPVDQAQSGLSKREWAEM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHH
MAALTPPTPG
HHHCCCCCCC
>Mature Secondary Structure 
PLSDSDRTEIEAARAETTPTRRATVPTLEAMLFSAIPVLDHGFVRVVDYMGDDAAVVQA
CCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ARVSYGRGTRKVSEDEGLIRYLMRHRHSTPFEMCEIKLHVKLPIFVARQWIRHRTANVNE
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHCCCCHH
YSARYSVMDREFYIPSPANLAAQSASNRQGRGDLLEGDEASEVLAMLRADAERNYNHYER
HHHHHHHHCCEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHH
MLNEGGADPSRRGLARELARMNLTLNTYTQWYWKTDLHNLFHFLSLRADPHAQYEIRAYA
HHHCCCCCHHHHHHHHHHHHHCCEEEHHHHHEEHHHHHHHHHHHHHCCCCCCCHHHHHHH
EAILDIARAWVPASCRAFEDYRMGAATFSATMLAALRRMLAGEPVDQAQSGLSKREWAEM
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHH
MAALTPPTPG
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA