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The map label for this gene is speA

Identifier: 148243477

GI number: 148243477

Start: 2070063

End: 2071985

Strand: Direct

Name: speA

Synonym: SynRCC307_2378

Alternate gene names: 148243477

Gene position: 2070063-2071985 (Clockwise)

Preceding gene: 148243475

Following gene: 148243478

Centisome position: 93.04

GC content: 62.77

Gene sequence:

>1923_bases
ATGGTGGTGGCCCCAAGCCAGGTGGAACAGCAGAACTGGACGCCGGCCGCCAGCGCTCAGCTCTATGGGCTCGATCAATG
GGGTGATCCCTATTTCAGCGTCAATGCGCGCGGCCACGTGCTGGTGCAGCCCCGCGGTGATCGCGGCGGGTCGTTGGATC
TGGTGGAGCTGGTGGAGGGATTGCAGAGCCGCGACCTGCAGTTGCCGCTGCTGATCCGCTTTGAAGACATCCTCGAAGAC
CGCCTAGAGCGGCTGCATGGCGCCTTTGAGCGGGCCATTGCCCAGTACGGCTATGGCGGCCACTACCAAGGCGTTTTCCC
GGTGAAATGCAACCAGCAGCGCCACGTGGTGGAGCAGCTGGTGGAAAGCGGCCGCCGCTGGCACTTCGGCCTGGAGGCCG
GCAGCAAAGCGGAGCTACTGATTGCGCTCTCGCTGCTGGATGACCCCAAGGCGCTGCTGATCTGCAATGGCTACAAAGAC
CAGCGCTACATCGAAACGGCGATCCTGGCGCGTCAACTGGGGCGTCAGCCCGTGGTTGTCATCGAGCAAGCCGATGAGGT
GCCGCGCATCATCGAAGCCAGCCGCAACCTTGGGGCAGCGCCTTTGATCGGCGTAAGGGCCAAGTTGTCGACCCGGAGCA
CCGGTCGCTGGGGCAGTTCGGTGGGCGAGAAGGCCAAGTTCGGTCTCTCGATCCCTGATCTACTGGCGACGGTGGAAGCC
CTGCGTGACGCCGATCTACTCGGTGACCTGCGTCTGCTGCACTTTCACGTCGGCAGCCAGATCTGCGATATCGCCGTGCT
GAAAGACGCCTTGCAGGAGGCCGGTCAGCTGTATGTCCAACTGGCTTCCCTGGGCGCACCAATGGGCTTCCTGGATGTGG
GCGGCGGCCTTGGCGTGGACTACGACGGCAGCCGCAGCGCCACAGCGGCATCAACGAACTACTCGCTGCAGAACTACGCC
AACGACGTGGTGGCCACCATCCGCGAGTGCTGCGAACCCCAGGGCATCGTCGTCCCCACTCTGGTGAGCGAAAGTGGCCG
TGCCATCGCCAGCCATTTCTCGGTGCTGGTGTTCAACGTGTTGGGCCAAAGCGGCGTCAACCAACCATCCATCCCCGAGG
CGGTGGAAGGTGAGGCCTTGATCGTGCGCAACCTGCGCGAAACCCTCTCCGGAATCGGGCCCGACAACCTGCAGGAAGCC
TGGAACGACGCGCTCAAGTTCAAAGATGACGCCCTGGCCGCGTTCCGTCTGGGCTACTTGAGCCTGACCGAACGGGGGAA
AGCCGAGCAGCTCTATTGGGCCTGCTGCAGCGCCATCGCTGATCTCCTGCCTGGTGAAGAGGAATTGCCCGATGAGCTCA
AAGGCCTCAAAGCGGCCTTTGCCAGCACCTATTACGCCAACCTCTCGGTCTTCCGTTCGGCCCCGGACACCTGGGCCATT
GACCAACTGTTCCCGGTGATGCCGATTCACCGGTTGGAGGAGCAGCCGCGCGAGCTCGGCAGCTTTGCCGACCTCACCTG
CGACTCCGACGGCAAGCTGGCGCGCTTCATTGCCAGCGGCAGCGCCAAGCCGCTGCTGGAACTCCATGAACTCAAAGACG
GCGAGCCCTATTGGATCGGTTTGTTTCTCGGAGGCGCCTATCAGGAGGTCATGGGCAACCTGCACAACCTCTTTGGCAGC
ACCAATGCCGTCTCCATTCGCCTCAGCCCGGGCGGGCCATACAGGGTCGAGCATGTAGTGCGCGGCCAAACCAACTCCGA
TGTGCTCGAGGCCATGGAACACAACCCCGAAGCGCTACTCGAACGGCTGCGGCAAGCCAGCGAAGAAGCGATCGGCAGCG
GTGATCTATCGATCAGTGCAGCCAGGCGCTTGATGCAGCACTTGGAAGGCAGCCTGCGGCAAACCACTTACCTCGAGGAA
TAA

Upstream 100 bases:

>100_bases
GGCCGCCCTACCGCTTGGCAAGCACACCCACATCAGTGGGAGCGCAGATGGCCGAGCCTTCCTACATTTCACTCATCAGA
TGAATTGATGGGCGGCGTCG

Downstream 100 bases:

>100_bases
AAGCAGCGCTATCAAAGAGATAGAAGCTGGGCCCACATGTGGGGCGACGAACCACAACTGGAAGCCTTCCGTGAGCGCCT
GAAGGTGCTGCTGGAGGCCC

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MVVAPSQVEQQNWTPAASAQLYGLDQWGDPYFSVNARGHVLVQPRGDRGGSLDLVELVEGLQSRDLQLPLLIRFEDILED
RLERLHGAFERAIAQYGYGGHYQGVFPVKCNQQRHVVEQLVESGRRWHFGLEAGSKAELLIALSLLDDPKALLICNGYKD
QRYIETAILARQLGRQPVVVIEQADEVPRIIEASRNLGAAPLIGVRAKLSTRSTGRWGSSVGEKAKFGLSIPDLLATVEA
LRDADLLGDLRLLHFHVGSQICDIAVLKDALQEAGQLYVQLASLGAPMGFLDVGGGLGVDYDGSRSATAASTNYSLQNYA
NDVVATIRECCEPQGIVVPTLVSESGRAIASHFSVLVFNVLGQSGVNQPSIPEAVEGEALIVRNLRETLSGIGPDNLQEA
WNDALKFKDDALAAFRLGYLSLTERGKAEQLYWACCSAIADLLPGEEELPDELKGLKAAFASTYYANLSVFRSAPDTWAI
DQLFPVMPIHRLEEQPRELGSFADLTCDSDGKLARFIASGSAKPLLELHELKDGEPYWIGLFLGGAYQEVMGNLHNLFGS
TNAVSIRLSPGGPYRVEHVVRGQTNSDVLEAMEHNPEALLERLRQASEEAIGSGDLSISAARRLMQHLEGSLRQTTYLEE

Sequences:

>Translated_640_residues
MVVAPSQVEQQNWTPAASAQLYGLDQWGDPYFSVNARGHVLVQPRGDRGGSLDLVELVEGLQSRDLQLPLLIRFEDILED
RLERLHGAFERAIAQYGYGGHYQGVFPVKCNQQRHVVEQLVESGRRWHFGLEAGSKAELLIALSLLDDPKALLICNGYKD
QRYIETAILARQLGRQPVVVIEQADEVPRIIEASRNLGAAPLIGVRAKLSTRSTGRWGSSVGEKAKFGLSIPDLLATVEA
LRDADLLGDLRLLHFHVGSQICDIAVLKDALQEAGQLYVQLASLGAPMGFLDVGGGLGVDYDGSRSATAASTNYSLQNYA
NDVVATIRECCEPQGIVVPTLVSESGRAIASHFSVLVFNVLGQSGVNQPSIPEAVEGEALIVRNLRETLSGIGPDNLQEA
WNDALKFKDDALAAFRLGYLSLTERGKAEQLYWACCSAIADLLPGEEELPDELKGLKAAFASTYYANLSVFRSAPDTWAI
DQLFPVMPIHRLEEQPRELGSFADLTCDSDGKLARFIASGSAKPLLELHELKDGEPYWIGLFLGGAYQEVMGNLHNLFGS
TNAVSIRLSPGGPYRVEHVVRGQTNSDVLEAMEHNPEALLERLRQASEEAIGSGDLSISAARRLMQHLEGSLRQTTYLEE
>Mature_640_residues
MVVAPSQVEQQNWTPAASAQLYGLDQWGDPYFSVNARGHVLVQPRGDRGGSLDLVELVEGLQSRDLQLPLLIRFEDILED
RLERLHGAFERAIAQYGYGGHYQGVFPVKCNQQRHVVEQLVESGRRWHFGLEAGSKAELLIALSLLDDPKALLICNGYKD
QRYIETAILARQLGRQPVVVIEQADEVPRIIEASRNLGAAPLIGVRAKLSTRSTGRWGSSVGEKAKFGLSIPDLLATVEA
LRDADLLGDLRLLHFHVGSQICDIAVLKDALQEAGQLYVQLASLGAPMGFLDVGGGLGVDYDGSRSATAASTNYSLQNYA
NDVVATIRECCEPQGIVVPTLVSESGRAIASHFSVLVFNVLGQSGVNQPSIPEAVEGEALIVRNLRETLSGIGPDNLQEA
WNDALKFKDDALAAFRLGYLSLTERGKAEQLYWACCSAIADLLPGEEELPDELKGLKAAFASTYYANLSVFRSAPDTWAI
DQLFPVMPIHRLEEQPRELGSFADLTCDSDGKLARFIASGSAKPLLELHELKDGEPYWIGLFLGGAYQEVMGNLHNLFGS
TNAVSIRLSPGGPYRVEHVVRGQTNSDVLEAMEHNPEALLERLRQASEEAIGSGDLSISAARRLMQHLEGSLRQTTYLEE

Specific function: Catalyzes the biosynthesis of agmatine from arginine

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily

Homologues:

Organism=Escherichia coli, GI1789307, Length=626, Percent_Identity=37.6996805111821, Blast_Score=435, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEA_SYNR3 (A5GWM2)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001228634.1
- ProteinModelPortal:   A5GWM2
- STRING:   A5GWM2
- GeneID:   5156587
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_2378
- eggNOG:   COG1166
- HOGENOM:   HBG321436
- OMA:   TCDSDGE
- ProtClustDB:   PRK05354
- HAMAP:   MF_01417
- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183
- Gene3D:   G3DSA:2.40.37.10
- PANTHER:   PTHR11482:SF3
- PIRSF:   PIRSF001336
- PRINTS:   PR01180
- PRINTS:   PR01179
- TIGRFAMs:   TIGR01273

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC; SSF50621 Racem_decarbox_C

EC number: =4.1.1.19

Molecular weight: Translated: 69863; Mature: 69863

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00878 ODR_DC_2_1; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVAPSQVEQQNWTPAASAQLYGLDQWGDPYFSVNARGHVLVQPRGDRGGSLDLVELVEG
CCCCCCHHHHCCCCCCCCCEEEECCCCCCCCEEECCCEEEEEEECCCCCCCCHHHHHHHH
LQSRDLQLPLLIRFEDILEDRLERLHGAFERAIAQYGYGGHYQGVFPVKCNQQRHVVEQL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHH
VESGRRWHFGLEAGSKAELLIALSLLDDPKALLICNGYKDQRYIETAILARQLGRQPVVV
HHCCCCEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
IEQADEVPRIIEASRNLGAAPLIGVRAKLSTRSTGRWGSSVGEKAKFGLSIPDLLATVEA
EECCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHCCHHHCCCCHHHHHHHHHH
LRDADLLGDLRLLHFHVGSQICDIAVLKDALQEAGQLYVQLASLGAPMGFLDVGGGLGVD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
YDGSRSATAASTNYSLQNYANDVVATIRECCEPQGIVVPTLVSESGRAIASHFSVLVFNV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LGQSGVNQPSIPEAVEGEALIVRNLRETLSGIGPDNLQEAWNDALKFKDDALAAFRLGYL
HCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
SLTERGKAEQLYWACCSAIADLLPGEEELPDELKGLKAAFASTYYANLSVFRSAPDTWAI
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQLFPVMPIHRLEEQPRELGSFADLTCDSDGKLARFIASGSAKPLLELHELKDGEPYWIG
HHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEE
LFLGGAYQEVMGNLHNLFGSTNAVSIRLSPGGPYRVEHVVRGQTNSDVLEAMEHNPEALL
EEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEHHEECCCCCHHHHHHHHCCHHHHH
ERLRQASEEAIGSGDLSISAARRLMQHLEGSLRQTTYLEE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure
MVVAPSQVEQQNWTPAASAQLYGLDQWGDPYFSVNARGHVLVQPRGDRGGSLDLVELVEG
CCCCCCHHHHCCCCCCCCCEEEECCCCCCCCEEECCCEEEEEEECCCCCCCCHHHHHHHH
LQSRDLQLPLLIRFEDILEDRLERLHGAFERAIAQYGYGGHYQGVFPVKCNQQRHVVEQL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHH
VESGRRWHFGLEAGSKAELLIALSLLDDPKALLICNGYKDQRYIETAILARQLGRQPVVV
HHCCCCEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
IEQADEVPRIIEASRNLGAAPLIGVRAKLSTRSTGRWGSSVGEKAKFGLSIPDLLATVEA
EECCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHCCHHHCCCCHHHHHHHHHH
LRDADLLGDLRLLHFHVGSQICDIAVLKDALQEAGQLYVQLASLGAPMGFLDVGGGLGVD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
YDGSRSATAASTNYSLQNYANDVVATIRECCEPQGIVVPTLVSESGRAIASHFSVLVFNV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LGQSGVNQPSIPEAVEGEALIVRNLRETLSGIGPDNLQEAWNDALKFKDDALAAFRLGYL
HCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
SLTERGKAEQLYWACCSAIADLLPGEEELPDELKGLKAAFASTYYANLSVFRSAPDTWAI
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQLFPVMPIHRLEEQPRELGSFADLTCDSDGKLARFIASGSAKPLLELHELKDGEPYWIG
HHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEE
LFLGGAYQEVMGNLHNLFGSTNAVSIRLSPGGPYRVEHVVRGQTNSDVLEAMEHNPEALL
EEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEHHEECCCCCHHHHHHHHCCHHHHH
ERLRQASEEAIGSGDLSISAARRLMQHLEGSLRQTTYLEE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA