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The map label for this gene is ndhA [H]

Identifier: 148243376

GI number: 148243376

Start: 1979748

End: 1980872

Strand: Direct

Name: ndhA [H]

Synonym: SynRCC307_2277

Alternate gene names: 148243376

Gene position: 1979748-1980872 (Clockwise)

Preceding gene: 148243375

Following gene: 148243377

Centisome position: 88.98

GC content: 61.42

Gene sequence:

>1125_bases
ATGAGCACCGCGTTCACCCTCGATTTAGAAACTGGCTTCCGGGGCCTGCTGGAAGCTGGCGGCGTTAGCCCTGGGCTCAG
CCGGCTGATCTGGCTGCCCCTGCCAATGCTGCTGGTGCTGGTGGCTGCCGTGGTTGGCGTGCTGGTGACGGTGTGGCTGG
AGCGCAAGATTTCCGCTGCGGTTCAGCAGCGCATCGGCCCTGAGTACGCCGGTGCCCTTGGCATCCTCCAGCCCCTGGCA
GATGGCCTGAAGCTGCTGGTTAAAGAAGACATCGTCCCGGCACGGGCCGATGGCCTGCTGTTCACCCTCGGACCGGTGCT
GGTCGTGGTCCCGGTGATCCTGTCCTGGCTGATCGTGCCTTTTGGCCAGAACCTGCTGATCAGCAATGTGGGGGTTGGAA
TTTTCCTCTGGGTGGCCCTCAGCAGCATTCAGCCCATTGGCCTGCTGATGAGTGGCTACTCGAGCAATAACAAGTATTCG
CTGCTGGGCGGCCTGCGGGCTGCAGCCCAATCGATCAGCTACGAAATCCCCCTGGCCCTGGCGGTGCTGGCGGTGGTGAT
GATGACCAACTCGCTCAGCACGGTCGACATCGTCGATCAGCAAACCGGTGCTGGAATTTTGAGTTGGAACATCTGGCGCC
AACCGGTGGGCTTTTTGATCTTCTGGATCTGCGCCCTGGCCGAATGCGAACGCCTCCCCTTCGACTTGCCTGAAGCGGAA
GAAGAGCTGGTGGCCGGCTACCAGACCGAGTACGCGGGCATGAAATTTGCCCTCTTCTACCTGGGCAGCTACATCAACTT
GGTGCTCTCAGCCCTGCTGGTGGCTGTGCTCTATCTGGGTGGCTGGGGCTTCCCCCTGCCGGTGGAAACCCTGGCCGGCT
GGCTAAGTCAGCCGATTGATGCCCCCTTGGTGCAAGTCATCACCGGATCGGTGGGCATTGTGATGACGGTGCTGAAGGCC
TACGTCCTGGTCTTCACCGCGATCCTGCTGCGCTGGACCGTGCCCCGCGTGCGCATCGACCAACTGCTGGATTTCGGCTG
GAAGTTTCTGCTGCCGATCGCCCTGGTCAACCTGCTGGTGACCGCCGCCTTGAAACTTGCTTTTCCTGCCGTCTTTGGCG
GCTAA

Upstream 100 bases:

>100_bases
TCTATACGGGCCTCGAAACCCGCAGCTGGCTTCCTACTGAGCAGAGAAGCGGGCACAATGGCGAGCCGACTGGGTAGGTT
GCCTGCAACGGTCTGCGCTG

Downstream 100 bases:

>100_bases
GCGCCCTCAAGCCTGCCCAAAGCGGGTCATGATTGACCCAACGCCTTTCCGCTCCGCCCCTCCACGCCTCCATGTTCGGC
TTTCTCAAGCAGGTCGGTGA

Product: NADH dehydrogenase subunit H

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit 1; NDH-1 subunit 1; NDH-A [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSTAFTLDLETGFRGLLEAGGVSPGLSRLIWLPLPMLLVLVAAVVGVLVTVWLERKISAAVQQRIGPEYAGALGILQPLA
DGLKLLVKEDIVPARADGLLFTLGPVLVVVPVILSWLIVPFGQNLLISNVGVGIFLWVALSSIQPIGLLMSGYSSNNKYS
LLGGLRAAAQSISYEIPLALAVLAVVMMTNSLSTVDIVDQQTGAGILSWNIWRQPVGFLIFWICALAECERLPFDLPEAE
EELVAGYQTEYAGMKFALFYLGSYINLVLSALLVAVLYLGGWGFPLPVETLAGWLSQPIDAPLVQVITGSVGIVMTVLKA
YVLVFTAILLRWTVPRVRIDQLLDFGWKFLLPIALVNLLVTAALKLAFPAVFGG

Sequences:

>Translated_374_residues
MSTAFTLDLETGFRGLLEAGGVSPGLSRLIWLPLPMLLVLVAAVVGVLVTVWLERKISAAVQQRIGPEYAGALGILQPLA
DGLKLLVKEDIVPARADGLLFTLGPVLVVVPVILSWLIVPFGQNLLISNVGVGIFLWVALSSIQPIGLLMSGYSSNNKYS
LLGGLRAAAQSISYEIPLALAVLAVVMMTNSLSTVDIVDQQTGAGILSWNIWRQPVGFLIFWICALAECERLPFDLPEAE
EELVAGYQTEYAGMKFALFYLGSYINLVLSALLVAVLYLGGWGFPLPVETLAGWLSQPIDAPLVQVITGSVGIVMTVLKA
YVLVFTAILLRWTVPRVRIDQLLDFGWKFLLPIALVNLLVTAALKLAFPAVFGG
>Mature_373_residues
STAFTLDLETGFRGLLEAGGVSPGLSRLIWLPLPMLLVLVAAVVGVLVTVWLERKISAAVQQRIGPEYAGALGILQPLAD
GLKLLVKEDIVPARADGLLFTLGPVLVVVPVILSWLIVPFGQNLLISNVGVGIFLWVALSSIQPIGLLMSGYSSNNKYSL
LGGLRAAAQSISYEIPLALAVLAVVMMTNSLSTVDIVDQQTGAGILSWNIWRQPVGFLIFWICALAECERLPFDLPEAEE
ELVAGYQTEYAGMKFALFYLGSYINLVLSALLVAVLYLGGWGFPLPVETLAGWLSQPIDAPLVQVITGSVGIVMTVLKAY
VLVFTAILLRWTVPRVRIDQLLDFGWKFLLPIALVNLLVTAALKLAFPAVFGG

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=306, Percent_Identity=33.3333333333333, Blast_Score=159, Evalue=5e-39,
Organism=Escherichia coli, GI1788618, Length=340, Percent_Identity=37.9411764705882, Blast_Score=226, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: 1.6.5.3

Molecular weight: Translated: 40242; Mature: 40110

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAFTLDLETGFRGLLEAGGVSPGLSRLIWLPLPMLLVLVAAVVGVLVTVWLERKISAA
CCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQQRIGPEYAGALGILQPLADGLKLLVKEDIVPARADGLLFTLGPVLVVVPVILSWLIVP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FGQNLLISNVGVGIFLWVALSSIQPIGLLMSGYSSNNKYSLLGGLRAAAQSISYEIPLAL
CCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AVLAVVMMTNSLSTVDIVDQQTGAGILSWNIWRQPVGFLIFWICALAECERLPFDLPEAE
HHHHHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
EELVAGYQTEYAGMKFALFYLGSYINLVLSALLVAVLYLGGWGFPLPVETLAGWLSQPID
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC
APLVQVITGSVGIVMTVLKAYVLVFTAILLRWTVPRVRIDQLLDFGWKFLLPIALVNLLV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TAALKLAFPAVFGG
HHHHHHHHHHHCCC
>Mature Secondary Structure 
STAFTLDLETGFRGLLEAGGVSPGLSRLIWLPLPMLLVLVAAVVGVLVTVWLERKISAA
CCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQQRIGPEYAGALGILQPLADGLKLLVKEDIVPARADGLLFTLGPVLVVVPVILSWLIVP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FGQNLLISNVGVGIFLWVALSSIQPIGLLMSGYSSNNKYSLLGGLRAAAQSISYEIPLAL
CCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AVLAVVMMTNSLSTVDIVDQQTGAGILSWNIWRQPVGFLIFWICALAECERLPFDLPEAE
HHHHHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
EELVAGYQTEYAGMKFALFYLGSYINLVLSALLVAVLYLGGWGFPLPVETLAGWLSQPID
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC
APLVQVITGSVGIVMTVLKAYVLVFTAILLRWTVPRVRIDQLLDFGWKFLLPIALVNLLV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TAALKLAFPAVFGG
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA