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The map label for this gene is alr [H]

Identifier: 148243246

GI number: 148243246

Start: 1849244

End: 1850431

Strand: Direct

Name: alr [H]

Synonym: SynRCC307_2147

Alternate gene names: 148243246

Gene position: 1849244-1850431 (Clockwise)

Preceding gene: 148243244

Following gene: 148243247

Centisome position: 83.12

GC content: 64.39

Gene sequence:

>1188_bases
ATGCAGCATGAGTCCCTGCCAGGGCTGACGCGGGAGATGATCCCGTCGGTGCAACCACAGCAGCGGGCTTGGCTGGAGAT
TGATCGCGACGCCATTCGCTACAACACAGCACAGCTGAAGGGCTCGCTGAGTCCCGGTTGCGCCTTGATGGCTGTGGTCA
AGGCCGATGGCTATGGCCATGGCGCCGTGACGGTTGCTGAAGCTGCGCTCGATGGCGGTGCCAGCAGCTTTGGGGTGGCC
ACCCTCGCTGAAGGCATCGAACTTCGGCAAGCCGGAATCGAGGCCCCGATCCTGGTGCTGGGGAACCTGCAGCAGCCCGA
AGAATTCCGCTGCTGCCTGCACTGGCAACTCAGTCCCACGATCAGCAGCCTCAGGCAGGGGTTGATCGGCAGCAATGTGG
GTGTTGCCGGGGGGAAGCCATTGCTGGCCCACCTCAAGCTCGACACCGGCATGGCCCGGCTGGGCATCGACTGGCAACAG
GGCCCCAAACTGCTGGAGGAGCTGCAACAGCTCGATGGCTTAAGCATCGCCGGGGTGTATTCCCATCTCGCCGATGCTGA
TAATCCCGACGGCTTGCTCAACGCCACCCAGCAGGAGCGTTTTGAAGCAGTCCTGCGCCGCTTCCATGAGCTGGAACTGA
AACCTGGCCTGCGGCATCTGGCCAACAGCGCCGGCACCCTCAGCAGCCCTGAGCTGCACTACGACATGGTGCGGGTGGGG
TTGTCGCTCTATGGCCACTCGCCAGCTGCGCACCTAAAACAACTGCCGCTGCGGCCCGCCATGAGCGTGCACGCCAAGGT
CACCCTGCTTCGCGATGTGCCCGCCGGCGCTGGGGTGAGTTACGGCCATCAGTTCCACACCACACGACCGAGCCGACTGG
CCGTGCTCGGCATTGGCTACGCAGATGGCGTCAGCCGCCGCCTCTCCGGGCAGATGGAGGTGTTAGCCGAGGGGCGCCGC
CTGCCCCAAGTCGGAGCCATCACCATGGACCAAATCGTGATCGACGCCACAGATCTGCCGGAGTTGGACATTGGCGATTC
GGTGACGCTGCTGGGCAGCAGCGGCAGTGAAACCATTGGCCCGCAGGCCTGGAGCGATGTCTGCCAGAGCATTCCATGGG
AGGTGCTTTGCAGCTTCAAACACCGCCTGCCCCGCCTGCCCCGCCTGCCCCGCCGACCGGAGCACTGA

Upstream 100 bases:

>100_bases
CGGCTCGTAAGACGCATTGAGAACGAGGACGTGGCCCATGCCAGCTTCCCGTATTGCAGGCATGCTATCTGGGTCAACAA
GTGCCCCGACGTCGTCTCTG

Downstream 100 bases:

>100_bases
TAGGCTTGGCCGACCGCTGGAGAGGTGGCTGAGCGGTTGAAAGCGGCTCCCTGCTAAGGAGTTACAGGAGGCAACTTCTG
TCGAGGGTTCGAATCCCTCC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQHESLPGLTREMIPSVQPQQRAWLEIDRDAIRYNTAQLKGSLSPGCALMAVVKADGYGHGAVTVAEAALDGGASSFGVA
TLAEGIELRQAGIEAPILVLGNLQQPEEFRCCLHWQLSPTISSLRQGLIGSNVGVAGGKPLLAHLKLDTGMARLGIDWQQ
GPKLLEELQQLDGLSIAGVYSHLADADNPDGLLNATQQERFEAVLRRFHELELKPGLRHLANSAGTLSSPELHYDMVRVG
LSLYGHSPAAHLKQLPLRPAMSVHAKVTLLRDVPAGAGVSYGHQFHTTRPSRLAVLGIGYADGVSRRLSGQMEVLAEGRR
LPQVGAITMDQIVIDATDLPELDIGDSVTLLGSSGSETIGPQAWSDVCQSIPWEVLCSFKHRLPRLPRLPRRPEH

Sequences:

>Translated_395_residues
MQHESLPGLTREMIPSVQPQQRAWLEIDRDAIRYNTAQLKGSLSPGCALMAVVKADGYGHGAVTVAEAALDGGASSFGVA
TLAEGIELRQAGIEAPILVLGNLQQPEEFRCCLHWQLSPTISSLRQGLIGSNVGVAGGKPLLAHLKLDTGMARLGIDWQQ
GPKLLEELQQLDGLSIAGVYSHLADADNPDGLLNATQQERFEAVLRRFHELELKPGLRHLANSAGTLSSPELHYDMVRVG
LSLYGHSPAAHLKQLPLRPAMSVHAKVTLLRDVPAGAGVSYGHQFHTTRPSRLAVLGIGYADGVSRRLSGQMEVLAEGRR
LPQVGAITMDQIVIDATDLPELDIGDSVTLLGSSGSETIGPQAWSDVCQSIPWEVLCSFKHRLPRLPRLPRRPEH
>Mature_395_residues
MQHESLPGLTREMIPSVQPQQRAWLEIDRDAIRYNTAQLKGSLSPGCALMAVVKADGYGHGAVTVAEAALDGGASSFGVA
TLAEGIELRQAGIEAPILVLGNLQQPEEFRCCLHWQLSPTISSLRQGLIGSNVGVAGGKPLLAHLKLDTGMARLGIDWQQ
GPKLLEELQQLDGLSIAGVYSHLADADNPDGLLNATQQERFEAVLRRFHELELKPGLRHLANSAGTLSSPELHYDMVRVG
LSLYGHSPAAHLKQLPLRPAMSVHAKVTLLRDVPAGAGVSYGHQFHTTRPSRLAVLGIGYADGVSRRLSGQMEVLAEGRR
LPQVGAITMDQIVIDATDLPELDIGDSVTLLGSSGSETIGPQAWSDVCQSIPWEVLCSFKHRLPRLPRLPRRPEH

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=336, Percent_Identity=33.6309523809524, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787439, Length=364, Percent_Identity=30.4945054945055, Blast_Score=148, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42591; Mature: 42591

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHESLPGLTREMIPSVQPQQRAWLEIDRDAIRYNTAQLKGSLSPGCALMAVVKADGYGH
CCCCCCCCHHHHHCCCCCCCHHHHHEECHHHHHCCHHHHCCCCCCCCEEEEEEECCCCCC
GAVTVAEAALDGGASSFGVATLAEGIELRQAGIEAPILVLGNLQQPEEFRCCLHWQLSPT
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHEEEEEEEECHH
ISSLRQGLIGSNVGVAGGKPLLAHLKLDTGMARLGIDWQQGPKLLEELQQLDGLSIAGVY
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHCCCHHCCHHHHHHHHHHCCCCHHHHH
SHLADADNPDGLLNATQQERFEAVLRRFHELELKPGLRHLANSAGTLSSPELHYDMVRVG
HHHCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHH
LSLYGHSPAAHLKQLPLRPAMSVHAKVTLLRDVPAGAGVSYGHQFHTTRPSRLAVLGIGY
HHHHCCCHHHHHHHCCCCCCHHHHEEEEEEEECCCCCCCCCCCEECCCCCCEEEEEECCH
ADGVSRRLSGQMEVLAEGRRLPQVGAITMDQIVIDATDLPELDIGDSVTLLGSSGSETIG
HHHHHHHHCCHHHHHHCCCCCCCCCCEEHHHEEEECCCCCCCCCCCCEEEEECCCCCCCC
PQAWSDVCQSIPWEVLCSFKHRLPRLPRLPRRPEH
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQHESLPGLTREMIPSVQPQQRAWLEIDRDAIRYNTAQLKGSLSPGCALMAVVKADGYGH
CCCCCCCCHHHHHCCCCCCCHHHHHEECHHHHHCCHHHHCCCCCCCCEEEEEEECCCCCC
GAVTVAEAALDGGASSFGVATLAEGIELRQAGIEAPILVLGNLQQPEEFRCCLHWQLSPT
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHEEEEEEEECHH
ISSLRQGLIGSNVGVAGGKPLLAHLKLDTGMARLGIDWQQGPKLLEELQQLDGLSIAGVY
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHCCCHHCCHHHHHHHHHHCCCCHHHHH
SHLADADNPDGLLNATQQERFEAVLRRFHELELKPGLRHLANSAGTLSSPELHYDMVRVG
HHHCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHH
LSLYGHSPAAHLKQLPLRPAMSVHAKVTLLRDVPAGAGVSYGHQFHTTRPSRLAVLGIGY
HHHHCCCHHHHHHHCCCCCCHHHHEEEEEEEECCCCCCCCCCCEECCCCCCEEEEEECCH
ADGVSRRLSGQMEVLAEGRRLPQVGAITMDQIVIDATDLPELDIGDSVTLLGSSGSETIG
HHHHHHHHCCHHHHHHCCCCCCCCCCEEHHHEEEECCCCCCCCCCCCEEEEECCCCCCCC
PQAWSDVCQSIPWEVLCSFKHRLPRLPRLPRRPEH
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]