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The map label for this gene is 148243188

Identifier: 148243188

GI number: 148243188

Start: 1805893

End: 1807026

Strand: Direct

Name: 148243188

Synonym: SynRCC307_2089

Alternate gene names: NA

Gene position: 1805893-1807026 (Clockwise)

Preceding gene: 148243187

Following gene: 148243189

Centisome position: 81.17

GC content: 62.7

Gene sequence:

>1134_bases
ATGAGCCAAAGCTTGCTCAAGGGCTTTGAAGTGGAGATGTACACCGGCCGCCCCGACGGCACGGTGGTGGGCTGCTCCAG
CGAAGCTGCCGCGGCCATCGACGGGATCGTCACCGAGCCCGACCGCCGCAACCTGGAATACATCACACCGCCTGAAGCCT
CCTATGCAGCGCAGCTCCAGCACTTGCTGGAGCCTCGCCAGCGCCTACGCCAGTGGTTGCAACAGCGTCAGCTCACCTTG
CTGCCGGGGAGCAGCCTGAGCCTTGGCAACAGCCAACACTTTGAGCGCTCCAATCCCGACAACCCTTATCACCAGTTCAT
CGAGGACAGCTACGGCACCCGTGTGGTGACCGCCAGCGTTCACATCAACTTTGGTCTGGAGAGCAGCGAAACGATCATGG
CGGCCTGCCGGCTGCTGCGCTGCGAAGCCGCACTGCTGCTGGCCCTCAGTGCCAGCTCCCCGTTCCTTGATGGCCAAGCC
ACAGGGGCCCACTCCCAACGCTGGCGGCAATTCCCCATCACCCCACAGCAGGTGCCGCTGTTTGAAAACCATCAGCACTA
CATCGATTGGATGCATACCCAGCTGGAACAACAGCAGATGCGCAACGTGCGTCACTTCTGGGGATCGGTGCGTCCCAATG
GACCGGAGCGACCGCAGCAGCTCAATCGCGTCGAGCTGCGGGTCTGCGATTTGGTGAGTGATCCGCGCGATCTACTCGCC
ATCACTGCGTTTGCGGAATTGCGGCTGCTGCAACTGATCAATCGGGGCCAGAGCGAAGATCCCCTATTCAGCAGTGAGCT
GAGCGCAGCAGAGCTGGCTGAGCTGGCCGACCACAACGACCAGCAAGCCGCCCTGACCAGCCTGGATGCTGAGCTGCGCC
ACTGGCGCGATGGCCGCTCCATCAGCGCGCGGCAGTGGATCCAAGACCAACTTCAAGACCTCAACGCCTGGGCAGACCAA
CAGCCCGCCATGGCCTGGCTTGATCGCCTGCCAGCACTGCTCGAGCGCGGCAACACCGCCATGCAATGGCTGCAGCGCCA
GCAGAGCGGTGAGAGCATCTCCGCCATCCTCAGCGCGGATATTGCGGCCCTAGCGGCCCTTGAGCAGGACTTGCTGATGG
ACGGTTTGGGATGA

Upstream 100 bases:

>100_bases
TTGTGGCCGACTCTCAGCCGACCGCCGAGCACGAGGAAACCCTCAACAAAGCCCGCGGCATGCTCAAGGCCCTGGCTTGC
CTCGAGCCAGGCCAACAGCC

Downstream 100 bases:

>100_bases
TCGAAACGTCTTCCACTGCTTCGACCTCGCGCATGCCGGCTTCGCAGACCGAGACAGTCCAGCCCGTCGGTCGCCGCACG
CTGCGTCAGCTGAACGAACG

Product: glutamate-cysteine ligase family 2 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSQSLLKGFEVEMYTGRPDGTVVGCSSEAAAAIDGIVTEPDRRNLEYITPPEASYAAQLQHLLEPRQRLRQWLQQRQLTL
LPGSSLSLGNSQHFERSNPDNPYHQFIEDSYGTRVVTASVHINFGLESSETIMAACRLLRCEAALLLALSASSPFLDGQA
TGAHSQRWRQFPITPQQVPLFENHQHYIDWMHTQLEQQQMRNVRHFWGSVRPNGPERPQQLNRVELRVCDLVSDPRDLLA
ITAFAELRLLQLINRGQSEDPLFSSELSAAELAELADHNDQQAALTSLDAELRHWRDGRSISARQWIQDQLQDLNAWADQ
QPAMAWLDRLPALLERGNTAMQWLQRQQSGESISAILSADIAALAALEQDLLMDGLG

Sequences:

>Translated_377_residues
MSQSLLKGFEVEMYTGRPDGTVVGCSSEAAAAIDGIVTEPDRRNLEYITPPEASYAAQLQHLLEPRQRLRQWLQQRQLTL
LPGSSLSLGNSQHFERSNPDNPYHQFIEDSYGTRVVTASVHINFGLESSETIMAACRLLRCEAALLLALSASSPFLDGQA
TGAHSQRWRQFPITPQQVPLFENHQHYIDWMHTQLEQQQMRNVRHFWGSVRPNGPERPQQLNRVELRVCDLVSDPRDLLA
ITAFAELRLLQLINRGQSEDPLFSSELSAAELAELADHNDQQAALTSLDAELRHWRDGRSISARQWIQDQLQDLNAWADQ
QPAMAWLDRLPALLERGNTAMQWLQRQQSGESISAILSADIAALAALEQDLLMDGLG
>Mature_376_residues
SQSLLKGFEVEMYTGRPDGTVVGCSSEAAAAIDGIVTEPDRRNLEYITPPEASYAAQLQHLLEPRQRLRQWLQQRQLTLL
PGSSLSLGNSQHFERSNPDNPYHQFIEDSYGTRVVTASVHINFGLESSETIMAACRLLRCEAALLLALSASSPFLDGQAT
GAHSQRWRQFPITPQQVPLFENHQHYIDWMHTQLEQQQMRNVRHFWGSVRPNGPERPQQLNRVELRVCDLVSDPRDLLAI
TAFAELRLLQLINRGQSEDPLFSSELSAAELAELADHNDQQAALTSLDAELRHWRDGRSISARQWIQDQLQDLNAWADQQ
PAMAWLDRLPALLERGNTAMQWLQRQQSGESISAILSADIAALAALEQDLLMDGLG

Specific function: ATP-dependent carboxylate-amine ligase [H]

COG id: COG2170

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carboxylate-amine ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011793
- InterPro:   IPR006336 [H]

Pfam domain/function: PF04107 GCS2 [H]

EC number: NA

Molecular weight: Translated: 42444; Mature: 42313

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSLLKGFEVEMYTGRPDGTVVGCSSEAAAAIDGIVTEPDRRNLEYITPPEASYAAQLQ
CCCHHHCCCEEEEEECCCCCCEEECCCCHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHH
HLLEPRQRLRQWLQQRQLTLLPGSSLSLGNSQHFERSNPDNPYHQFIEDSYGTRVVTASV
HHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEE
HINFGLESSETIMAACRLLRCEAALLLALSASSPFLDGQATGAHSQRWRQFPITPQQVPL
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC
FENHQHYIDWMHTQLEQQQMRNVRHFWGSVRPNGPERPQQLNRVELRVCDLVSDPRDLLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
ITAFAELRLLQLINRGQSEDPLFSSELSAAELAELADHNDQQAALTSLDAELRHWRDGRS
HHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
ISARQWIQDQLQDLNAWADQQPAMAWLDRLPALLERGNTAMQWLQRQQSGESISAILSAD
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHH
IAALAALEQDLLMDGLG
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQSLLKGFEVEMYTGRPDGTVVGCSSEAAAAIDGIVTEPDRRNLEYITPPEASYAAQLQ
CCHHHCCCEEEEEECCCCCCEEECCCCHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHH
HLLEPRQRLRQWLQQRQLTLLPGSSLSLGNSQHFERSNPDNPYHQFIEDSYGTRVVTASV
HHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEE
HINFGLESSETIMAACRLLRCEAALLLALSASSPFLDGQATGAHSQRWRQFPITPQQVPL
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC
FENHQHYIDWMHTQLEQQQMRNVRHFWGSVRPNGPERPQQLNRVELRVCDLVSDPRDLLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
ITAFAELRLLQLINRGQSEDPLFSSELSAAELAELADHNDQQAALTSLDAELRHWRDGRS
HHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
ISARQWIQDQLQDLNAWADQQPAMAWLDRLPALLERGNTAMQWLQRQQSGESISAILSAD
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHH
IAALAALEQDLLMDGLG
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]