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The map label for this gene is wzb [C]

Identifier: 148243167

GI number: 148243167

Start: 1788204

End: 1788677

Strand: Direct

Name: wzb [C]

Synonym: SynRCC307_2068

Alternate gene names: 148243167

Gene position: 1788204-1788677 (Clockwise)

Preceding gene: 148243166

Following gene: 148243170

Centisome position: 80.37

GC content: 63.29

Gene sequence:

>474_bases
ATGAGCTCCCAACCCACCCGCGTTCTGTTTGTTTGCCTCGGCAACATCTGCCGCTCACCGGCTGCCGAGGGGGTGTTTCT
CGATTTGCTTGAGCGTGAAAACCTCAACGATGCCTTTGAGGTGGATTCCGCTGGCACCGGGAACTGGCATGTGGGCAAAC
GCGCCGACCCGCGCATGCGCGCTGCGGCCGAACGCCGCGGCATCGACCTGCCGAGCCGCGCCCGTCAAATCGAGCCCGAG
GACCTCAGCCGCTTTGATTGGATCATCACCATGGATGACAGCAATCTGGCCAACGTGCGGGCCCTTGATCCCAGTGGCAG
CAGCCACGACCGCATCGTGCCGCTCACCAGCCACTGCAGCCGCCACCAGGCCAGCGAAGTGCCCGACCCCTACTACGGCG
GCGAGCAGGGGTTTGAGCATGTTCTCGATTTGCTCGAAGATGCCTGCAGCGGACTGCTCAAGCGTCTGCGTTGA

Upstream 100 bases:

>100_bases
CCCAGGCACGTGCCCTACTGCGGCAGAGGAGCCAACAGGAGATGGACGATACGCTCGTCGTTCGTTTGCGCGCGCTTCTC
GCCCTCGAGCGCCTGGCTGC

Downstream 100 bases:

>100_bases
GTGCCTCCACGGGCACCCACTCGCGGAATAGGGCAACGATCTGAGCCACCACCTCATCGATGCTGAGGCCATCACTAAGC
AACTCAACTGCGTCACTGGC

Product: low molecular weight protein-tyrosine-phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSSQPTRVLFVCLGNICRSPAAEGVFLDLLERENLNDAFEVDSAGTGNWHVGKRADPRMRAAAERRGIDLPSRARQIEPE
DLSRFDWIITMDDSNLANVRALDPSGSSHDRIVPLTSHCSRHQASEVPDPYYGGEQGFEHVLDLLEDACSGLLKRLR

Sequences:

>Translated_157_residues
MSSQPTRVLFVCLGNICRSPAAEGVFLDLLERENLNDAFEVDSAGTGNWHVGKRADPRMRAAAERRGIDLPSRARQIEPE
DLSRFDWIITMDDSNLANVRALDPSGSSHDRIVPLTSHCSRHQASEVPDPYYGGEQGFEHVLDLLEDACSGLLKRLR
>Mature_156_residues
SSQPTRVLFVCLGNICRSPAAEGVFLDLLERENLNDAFEVDSAGTGNWHVGKRADPRMRAAAERRGIDLPSRARQIEPED
LSRFDWIITMDDSNLANVRALDPSGSSHDRIVPLTSHCSRHQASEVPDPYYGGEQGFEHVLDLLEDACSGLLKRLR

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=157, Percent_Identity=38.8535031847134, Blast_Score=114, Evalue=2e-26,
Organism=Homo sapiens, GI4757714, Length=157, Percent_Identity=39.4904458598726, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI96304457, Length=83, Percent_Identity=45.7831325301205, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788375, Length=140, Percent_Identity=35.7142857142857, Blast_Score=64, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=152, Percent_Identity=34.2105263157895, Blast_Score=104, Evalue=7e-24,
Organism=Drosophila melanogaster, GI78706766, Length=149, Percent_Identity=42.2818791946309, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI78706768, Length=149, Percent_Identity=42.2818791946309, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI78706764, Length=126, Percent_Identity=44.4444444444444, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI78706770, Length=156, Percent_Identity=39.1025641025641, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78706772, Length=156, Percent_Identity=39.1025641025641, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78711846, Length=156, Percent_Identity=33.974358974359, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24648069, Length=113, Percent_Identity=31.858407079646, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17473; Mature: 17342

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQPTRVLFVCLGNICRSPAAEGVFLDLLERENLNDAFEVDSAGTGNWHVGKRADPRMR
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCHHHH
AAAERRGIDLPSRARQIEPEDLSRFDWIITMDDSNLANVRALDPSGSSHDRIVPLTSHCS
HHHHHCCCCCCHHHCCCCHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEHHHHHH
RHQASEVPDPYYGGEQGFEHVLDLLEDACSGLLKRLR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSQPTRVLFVCLGNICRSPAAEGVFLDLLERENLNDAFEVDSAGTGNWHVGKRADPRMR
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCHHHH
AAAERRGIDLPSRARQIEPEDLSRFDWIITMDDSNLANVRALDPSGSSHDRIVPLTSHCS
HHHHHCCCCCCHHHCCCCHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEHHHHHH
RHQASEVPDPYYGGEQGFEHVLDLLEDACSGLLKRLR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]