Click here to switch to the map view.

The map label for this gene is fkpA [H]

Identifier: 148242889

GI number: 148242889

Start: 1554826

End: 1555452

Strand: Direct

Name: fkpA [H]

Synonym: SynRCC307_1790

Alternate gene names: 148242889

Gene position: 1554826-1555452 (Clockwise)

Preceding gene: 148242888

Following gene: 148242890

Centisome position: 69.88

GC content: 62.84

Gene sequence:

>627_bases
ATGCGCGACATCCTGATCAGCTCCGCCGTTTGCGTGGGCTGCCTGATGCTGGCTCTGGTTAGCCAGATCGTGGCCCCCAC
CCCAGCCCAGGCCACTGCTCCTGCGGCAAGCGAAGTGCGCCCAGCCGCCAAGGCAGCAGCCGTCAACCCCGCTGCACCTC
CCGCTGAGCTCGATCCCAACGAGAGCAACCCTCGTCTGTTTGCGATGGCTCCCGAAGCCAGCGATCAGGTCGCCCAAGGT
TCAGCAGCTGATTTATTGGGTGGCGACATGGAAGCCACCAAAGAGCGCATGACCCCCTCAGGCCTCAAGATCACCGACCT
GGTGGAAGGCACAGGAACAGAAGCCCAAAGCGGCAACACCGTCTCGGTGAACTACCGCGGCACCTTGACCAACGGTCAGG
AGTTCGACAGCAGCTACCGCCGCAACCAGGCCTTCACCTTCCCCCTTGGCGGCGGGCGAGTGATCCGCGGCTGGGATGAA
GGCGTTATGGGCATGAAAGAAGGCGGCAAGCGTCGTCTGGTGATCCCACCGGATCTGGCCTATGGCTCCCGCGGTGCTGG
CGGTGTGATCGGGCCCAACGAAACCCTGATCTTTGAAATCGAGCTGGTGAAGGTGCAGGGCAACTGA

Upstream 100 bases:

>100_bases
AGGTGGATGAACTGCGGGGCCGCATTGATCGCCTTGAGCAACAGCTGCGTCAAAACGGCGAACTTCGCTGACAGAATCAA
TCGGTCTTTCTCAGCCCTTG

Downstream 100 bases:

>100_bases
ACCGGCCGGTTATCCCCACGCCTAGGCGACAGTGGAGGACCGGAGTCCATCGTTAAGATCGCCGCGACCGTTTGATCCGG
CCATGGCCCACACCCTCCCT

Product: FKBP-type peptidyl-prolyl cis-trans isomeras

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MRDILISSAVCVGCLMLALVSQIVAPTPAQATAPAASEVRPAAKAAAVNPAAPPAELDPNESNPRLFAMAPEASDQVAQG
SAADLLGGDMEATKERMTPSGLKITDLVEGTGTEAQSGNTVSVNYRGTLTNGQEFDSSYRRNQAFTFPLGGGRVIRGWDE
GVMGMKEGGKRRLVIPPDLAYGSRGAGGVIGPNETLIFEIELVKVQGN

Sequences:

>Translated_208_residues
MRDILISSAVCVGCLMLALVSQIVAPTPAQATAPAASEVRPAAKAAAVNPAAPPAELDPNESNPRLFAMAPEASDQVAQG
SAADLLGGDMEATKERMTPSGLKITDLVEGTGTEAQSGNTVSVNYRGTLTNGQEFDSSYRRNQAFTFPLGGGRVIRGWDE
GVMGMKEGGKRRLVIPPDLAYGSRGAGGVIGPNETLIFEIELVKVQGN
>Mature_208_residues
MRDILISSAVCVGCLMLALVSQIVAPTPAQATAPAASEVRPAAKAAAVNPAAPPAELDPNESNPRLFAMAPEASDQVAQG
SAADLLGGDMEATKERMTPSGLKITDLVEGTGTEAQSGNTVSVNYRGTLTNGQEFDSSYRRNQAFTFPLGGGRVIRGWDE
GVMGMKEGGKRRLVIPPDLAYGSRGAGGVIGPNETLIFEIELVKVQGN

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=99, Percent_Identity=48.4848484848485, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI17149844, Length=99, Percent_Identity=48.4848484848485, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI17149842, Length=99, Percent_Identity=48.4848484848485, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI224809329, Length=122, Percent_Identity=45.9016393442623, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI224809327, Length=122, Percent_Identity=45.9016393442623, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4758384, Length=122, Percent_Identity=45.9016393442623, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI17149836, Length=107, Percent_Identity=44.8598130841121, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI4503725, Length=107, Percent_Identity=44.8598130841121, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI224809331, Length=122, Percent_Identity=45.9016393442623, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI192448443, Length=117, Percent_Identity=41.025641025641, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI4758380, Length=107, Percent_Identity=43.9252336448598, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI4503729, Length=100, Percent_Identity=46, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI150010552, Length=106, Percent_Identity=38.6792452830189, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI33469985, Length=92, Percent_Identity=44.5652173913043, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI4503727, Length=98, Percent_Identity=41.8367346938776, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI8923659, Length=96, Percent_Identity=40.625, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI206725547, Length=100, Percent_Identity=41, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI31317231, Length=101, Percent_Identity=41.5841584158416, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1789745, Length=111, Percent_Identity=46.8468468468468, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI87082390, Length=108, Percent_Identity=43.5185185185185, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17540882, Length=114, Percent_Identity=41.2280701754386, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71993519, Length=100, Percent_Identity=48, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17561778, Length=104, Percent_Identity=43.2692307692308, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561782, Length=88, Percent_Identity=47.7272727272727, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506169, Length=97, Percent_Identity=38.1443298969072, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17506167, Length=97, Percent_Identity=38.1443298969072, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320727, Length=100, Percent_Identity=52, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324194, Length=106, Percent_Identity=47.1698113207547, Blast_Score=95, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323482, Length=113, Percent_Identity=42.4778761061947, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323566, Length=118, Percent_Identity=39.8305084745763, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647110, Length=112, Percent_Identity=53.5714285714286, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363946, Length=93, Percent_Identity=49.4623655913978, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17352457, Length=93, Percent_Identity=49.4623655913978, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24655568, Length=107, Percent_Identity=49.5327102803738, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21356629, Length=104, Percent_Identity=51.9230769230769, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24583150, Length=102, Percent_Identity=50, Blast_Score=94, Evalue=5e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21599; Mature: 21599

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50059 FKBP_PPIASE ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDILISSAVCVGCLMLALVSQIVAPTPAQATAPAASEVRPAAKAAAVNPAAPPAELDPN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCHHHHHHCCCCCCCCCCCCCC
ESNPRLFAMAPEASDQVAQGSAADLLGGDMEATKERMTPSGLKITDLVEGTGTEAQSGNT
CCCCEEEEECCCCCCHHHCCCCHHHCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCCE
VSVNYRGTLTNGQEFDSSYRRNQAFTFPLGGGRVIRGWDEGVMGMKEGGKRRLVIPPDLA
EEEEEEEEECCCHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCCCCEEEEECCCCC
YGSRGAGGVIGPNETLIFEIELVKVQGN
CCCCCCCCCCCCCCEEEEEEEEEEEECC
>Mature Secondary Structure
MRDILISSAVCVGCLMLALVSQIVAPTPAQATAPAASEVRPAAKAAAVNPAAPPAELDPN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCHHHHHHCCCCCCCCCCCCCC
ESNPRLFAMAPEASDQVAQGSAADLLGGDMEATKERMTPSGLKITDLVEGTGTEAQSGNT
CCCCEEEEECCCCCCHHHCCCCHHHCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCCE
VSVNYRGTLTNGQEFDSSYRRNQAFTFPLGGGRVIRGWDEGVMGMKEGGKRRLVIPPDLA
EEEEEEEEECCCHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCCCCEEEEECCCCC
YGSRGAGGVIGPNETLIFEIELVKVQGN
CCCCCCCCCCCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]