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The map label for this gene is argF [H]

Identifier: 148242854

GI number: 148242854

Start: 1536539

End: 1537477

Strand: Direct

Name: argF [H]

Synonym: SynRCC307_1755

Alternate gene names: 148242854

Gene position: 1536539-1537477 (Clockwise)

Preceding gene: 148242853

Following gene: 148242855

Centisome position: 69.06

GC content: 64.22

Gene sequence:

>939_bases
ATGGCCGCCGAGCTTTCGACCCTGAATGGGCTCGATTTCCTCTCCTCTGCTGATCTCAACGGCGCCCAAACCCAGGCGCT
GTTGACCCTGGCGGCCGATATCAAGGCAGGACGCCGCAACCCGCGCCTCGACGGCAAGGTGTTGGGGTTGATTTTTTCCA
AGGCCTCCACCCGCACGCGGGTGAGCTTCACCGTGGCGATGGCGCGCCTGGGCGGGCAAACCATCGACCTCAACCCATCA
GTCAGCCAGGTGGGCCGTGGTGAACCGATTAAAGACACCGCCCGAGTGTTGAGCCGCTACCTCAACGCCGTAGCCATTCG
CACCTTCGCCCAGAGCGATCTGCAGGCCTACGCCGATGCGGCCTCGATCCCGATCATCAATGCCCTCACCGACCTGGAGC
ACCCCTGCCAGGCGCTGGCCGACTACCTGACCATGCAGGAGGCCTTCGGCTCCCTGGAAGGGCTGACCATGACTTACGTG
GGCGATGGCAACAACGTGGCCCATTCACTGCTCATTGCTGGCGCGCTATTGGGCGTGAACGTGCGCATCGGCTGCCCCGC
GGGCTTCTATCCCCTCGATGAAGTAGTGGCCCAGGCCAAGGCCATCGCAGCGGGGCGCAGCGAGATCGTGATCAGCGAAG
ACCCCGCTGAAGCCGTGCGCGGGGCCCATGCCGTCTACACCGATGTGTGGGCGTCCATGGGCCAAGAAGAAGAGCAGAGC
ACCCGCGTGCAGGCCTTCCGCGGCTTCTGCGTGAATGAATCGCTGATGCGCCACGCCGATGCCAAGGCGATCGTGTTGCA
CTGCCTGCCGGCCCACCGCGGCGAAGAGATCAGCGCCGAGGTGATGGAGAGCTCCGCCAGCCGCATCTTTGATCAGGCCG
AGAACCGCTTGCATGCCCAACAGGCTCTGTTGGCAACACTTTTGGGCGCCGAGGGGTAG

Upstream 100 bases:

>100_bases
AAGAGCTGCTCTCCCGCAGCGTTGACCCTCAGCCCGTTGCAGCCTGAGTGCTTGACGGAATTCCATCTCATCACTGATAA
GTGACCTTTGGTTCTGAGTG

Downstream 100 bases:

>100_bases
ACAAACCGGCTTTTCAGTGGCACAAATGTATTAGTGCTGTTGCCCACGCCCCTGCCATGCCCCTTGAGGCCCTGACCGCC
GCCCAGCAAGAGCTCTACGA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MAAELSTLNGLDFLSSADLNGAQTQALLTLAADIKAGRRNPRLDGKVLGLIFSKASTRTRVSFTVAMARLGGQTIDLNPS
VSQVGRGEPIKDTARVLSRYLNAVAIRTFAQSDLQAYADAASIPIINALTDLEHPCQALADYLTMQEAFGSLEGLTMTYV
GDGNNVAHSLLIAGALLGVNVRIGCPAGFYPLDEVVAQAKAIAAGRSEIVISEDPAEAVRGAHAVYTDVWASMGQEEEQS
TRVQAFRGFCVNESLMRHADAKAIVLHCLPAHRGEEISAEVMESSASRIFDQAENRLHAQQALLATLLGAEG

Sequences:

>Translated_312_residues
MAAELSTLNGLDFLSSADLNGAQTQALLTLAADIKAGRRNPRLDGKVLGLIFSKASTRTRVSFTVAMARLGGQTIDLNPS
VSQVGRGEPIKDTARVLSRYLNAVAIRTFAQSDLQAYADAASIPIINALTDLEHPCQALADYLTMQEAFGSLEGLTMTYV
GDGNNVAHSLLIAGALLGVNVRIGCPAGFYPLDEVVAQAKAIAAGRSEIVISEDPAEAVRGAHAVYTDVWASMGQEEEQS
TRVQAFRGFCVNESLMRHADAKAIVLHCLPAHRGEEISAEVMESSASRIFDQAENRLHAQQALLATLLGAEG
>Mature_311_residues
AAELSTLNGLDFLSSADLNGAQTQALLTLAADIKAGRRNPRLDGKVLGLIFSKASTRTRVSFTVAMARLGGQTIDLNPSV
SQVGRGEPIKDTARVLSRYLNAVAIRTFAQSDLQAYADAASIPIINALTDLEHPCQALADYLTMQEAFGSLEGLTMTYVG
DGNNVAHSLLIAGALLGVNVRIGCPAGFYPLDEVVAQAKAIAAGRSEIVISEDPAEAVRGAHAVYTDVWASMGQEEEQST
RVQAFRGFCVNESLMRHADAKAIVLHCLPAHRGEEISAEVMESSASRIFDQAENRLHAQQALLATLLGAEG

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=307, Percent_Identity=42.3452768729642, Blast_Score=244, Evalue=5e-65,
Organism=Homo sapiens, GI18105007, Length=316, Percent_Identity=31.6455696202532, Blast_Score=122, Evalue=5e-28,
Organism=Escherichia coli, GI1786469, Length=333, Percent_Identity=40.5405405405405, Blast_Score=227, Evalue=9e-61,
Organism=Escherichia coli, GI1790703, Length=324, Percent_Identity=39.8148148148148, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI2367364, Length=308, Percent_Identity=30.8441558441558, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994908, Length=319, Percent_Identity=28.2131661442006, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193204318, Length=295, Percent_Identity=28.4745762711864, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322373, Length=281, Percent_Identity=34.1637010676157, Blast_Score=169, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6322331, Length=326, Percent_Identity=30.3680981595092, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24642586, Length=280, Percent_Identity=33.9285714285714, Blast_Score=124, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 33120; Mature: 32989

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAELSTLNGLDFLSSADLNGAQTQALLTLAADIKAGRRNPRLDGKVLGLIFSKASTRTR
CCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHH
VSFTVAMARLGGQTIDLNPSVSQVGRGEPIKDTARVLSRYLNAVAIRTFAQSDLQAYADA
HHHHHHHHHHCCCEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIPIINALTDLEHPCQALADYLTMQEAFGSLEGLTMTYVGDGNNVAHSLLIAGALLGVN
HCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCE
VRIGCPAGFYPLDEVVAQAKAIAAGRSEIVISEDPAEAVRGAHAVYTDVWASMGQEEEQS
EEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHH
TRVQAFRGFCVNESLMRHADAKAIVLHCLPAHRGEEISAEVMESSASRIFDQAENRLHAQ
HHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QALLATLLGAEG
HHHHHHHHCCCC
>Mature Secondary Structure 
AAELSTLNGLDFLSSADLNGAQTQALLTLAADIKAGRRNPRLDGKVLGLIFSKASTRTR
CCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHH
VSFTVAMARLGGQTIDLNPSVSQVGRGEPIKDTARVLSRYLNAVAIRTFAQSDLQAYADA
HHHHHHHHHHCCCEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIPIINALTDLEHPCQALADYLTMQEAFGSLEGLTMTYVGDGNNVAHSLLIAGALLGVN
HCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCE
VRIGCPAGFYPLDEVVAQAKAIAAGRSEIVISEDPAEAVRGAHAVYTDVWASMGQEEEQS
EEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHH
TRVQAFRGFCVNESLMRHADAKAIVLHCLPAHRGEEISAEVMESSASRIFDQAENRLHAQ
HHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QALLATLLGAEG
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]