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The map label for this gene is cobQ

Identifier: 148242798

GI number: 148242798

Start: 1483022

End: 1484503

Strand: Direct

Name: cobQ

Synonym: SynRCC307_1699

Alternate gene names: 148242798

Gene position: 1483022-1484503 (Clockwise)

Preceding gene: 148242797

Following gene: 148242800

Centisome position: 66.66

GC content: 64.44

Gene sequence:

>1482_bases
GTGACGCCGCCCACCCCCTTGATGGTGCTGGGCACGAGCAGTGGTGCCGGCAAATCCCTGATGACAGCGGCGCTCTGCCG
AGTGCTCAAACGCCGCGGCGAGCAGCCCCTGCCCTTTAAGGGGCAGAACATGAGCAACAACGCCTGGGTGGATCAAAGCG
GCGGCGAGATGGCCTATTCCCAAGCGCTGCAGTCTTGGGCCGCTGGGCTTGAGCCGAACTGCGCCATGAACCCGGTGTTG
CTCAAACCCCAGGGCAACAGCACCAGTGAAGTGATCCATGGCGGTGAATCAGTTGGCATGGCGCGGGCCGAGACCTACTA
CCAGGAGTGGTTCAAACCAGGATGGCTCGCGATTCGCCAAGGACTGGAGCAATTGCGACAGCAACACCCCCACGGCCGGC
TGGTGCTGGAAGGAGCCGGCAGCCCAGTGGAGGTGAACCTGCAGCACCGCGACCTCACCAATCTGCGCTTGGCCCAATAC
CTGCGGGCCCGCTGCTTGCTGGTGGCTGATATCGAGCGGGGCGGCGTCTTTGCCCAACTGGTGGGCACCTTGCAATTGCT
GCGGCCGGTGGAGCGGCCCCTGGTGAAGGGCCTGTTGATCAATCGCTTCCGCGGCCGCCAGGAACTGTTTGACCCAGGCG
TCAGCTGGCTTTCAGACAACACCGGCGTGCCGGTGCTTGGCGTGATGCCCTGGCTTGATGAACTCTTTCCGCCAGAAGAC
TCCCTGGATCTGTTGGAGCGCCGCGGCCGCAAAGCCAATGCTGAGCTGGAGATCGCCGTGTTGCGGCTGCCCTCCCTCAG
CAACTTCTCGGATCTCGATCCACTAGAGGCCGAACCCAGCGTGCAACTGCGCTGGGTGCAGCCCGGCGAAGCCCTCGGCC
AGCCCGATGCGGTGGTGCTGCCAGGCAGCAAACAAACCCTGCGGGATCTCAAGGCGCTGCAGGCCAGCGGCCTGGCTCGT
GAACTGCAGCGCTTCAGCGCTGGTGGCGGCGCTGTGCTCGGCATTTGCGGCGGCCTGCAGATGCTCGGCCGTGAACTGCT
GGATCCTGATGGGCTGGAGGGAGCGGCAGGCGCTAGTGCAGCGGGGCTGAATCTGCTGCCGCTGCAAACCCGCTTTGGCG
GCAGCAAAGCCCTACGCCAGCGGCAGGCTGTCGCGCACTGGCCAACCGCTGAGTCCTGCCCAATCGAAGGTTTCGAGCTG
CATCGCGGCAGCACCATCGCCCTTGAGCCCCTGCAAGCGCTGTGCCAAGAAGAGGGGCTGGGCTGGGTGCAAGGCCAAGT
GGCCGGCAGCTACCTGCATGGCCTATTGGAGAACGGCCGCTGGCGCCGCCAGTGGCTCAACCAGCTCAGGCGCCGCAAAC
AGCTCCCCGAACTCGCCGAAGACCAAGGGCATCACTCCCTGCAGCGCGAAGAACTGCTCGATCGGCTCGCTGATGCCTTT
GAAGCCAATGTTGATCTAACGCCGCTGATTAGTGATCCGTGA

Upstream 100 bases:

>100_bases
CCATGGGCAACCAACTGCTCAAGCGCTGGCCGCAAGGCTGGCCGCCCGCAAGCCCCTGGCAGCGGCTGCGCCATGGCATC
CGCCGGCGCTGGCCACGGCT

Downstream 100 bases:

>100_bases
GCTCTTCGGTGATGGTGACGCTCAGATCGGAGTGGGGGGTGCGCAGTTCAATCAACTTCTGGTAGTCCGCTGATTCGTAG
GCCGCCACCGCCGCCTCGCG

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MTPPTPLMVLGTSSGAGKSLMTAALCRVLKRRGEQPLPFKGQNMSNNAWVDQSGGEMAYSQALQSWAAGLEPNCAMNPVL
LKPQGNSTSEVIHGGESVGMARAETYYQEWFKPGWLAIRQGLEQLRQQHPHGRLVLEGAGSPVEVNLQHRDLTNLRLAQY
LRARCLLVADIERGGVFAQLVGTLQLLRPVERPLVKGLLINRFRGRQELFDPGVSWLSDNTGVPVLGVMPWLDELFPPED
SLDLLERRGRKANAELEIAVLRLPSLSNFSDLDPLEAEPSVQLRWVQPGEALGQPDAVVLPGSKQTLRDLKALQASGLAR
ELQRFSAGGGAVLGICGGLQMLGRELLDPDGLEGAAGASAAGLNLLPLQTRFGGSKALRQRQAVAHWPTAESCPIEGFEL
HRGSTIALEPLQALCQEEGLGWVQGQVAGSYLHGLLENGRWRRQWLNQLRRRKQLPELAEDQGHHSLQREELLDRLADAF
EANVDLTPLISDP

Sequences:

>Translated_493_residues
MTPPTPLMVLGTSSGAGKSLMTAALCRVLKRRGEQPLPFKGQNMSNNAWVDQSGGEMAYSQALQSWAAGLEPNCAMNPVL
LKPQGNSTSEVIHGGESVGMARAETYYQEWFKPGWLAIRQGLEQLRQQHPHGRLVLEGAGSPVEVNLQHRDLTNLRLAQY
LRARCLLVADIERGGVFAQLVGTLQLLRPVERPLVKGLLINRFRGRQELFDPGVSWLSDNTGVPVLGVMPWLDELFPPED
SLDLLERRGRKANAELEIAVLRLPSLSNFSDLDPLEAEPSVQLRWVQPGEALGQPDAVVLPGSKQTLRDLKALQASGLAR
ELQRFSAGGGAVLGICGGLQMLGRELLDPDGLEGAAGASAAGLNLLPLQTRFGGSKALRQRQAVAHWPTAESCPIEGFEL
HRGSTIALEPLQALCQEEGLGWVQGQVAGSYLHGLLENGRWRRQWLNQLRRRKQLPELAEDQGHHSLQREELLDRLADAF
EANVDLTPLISDP
>Mature_492_residues
TPPTPLMVLGTSSGAGKSLMTAALCRVLKRRGEQPLPFKGQNMSNNAWVDQSGGEMAYSQALQSWAAGLEPNCAMNPVLL
KPQGNSTSEVIHGGESVGMARAETYYQEWFKPGWLAIRQGLEQLRQQHPHGRLVLEGAGSPVEVNLQHRDLTNLRLAQYL
RARCLLVADIERGGVFAQLVGTLQLLRPVERPLVKGLLINRFRGRQELFDPGVSWLSDNTGVPVLGVMPWLDELFPPEDS
LDLLERRGRKANAELEIAVLRLPSLSNFSDLDPLEAEPSVQLRWVQPGEALGQPDAVVLPGSKQTLRDLKALQASGLARE
LQRFSAGGGAVLGICGGLQMLGRELLDPDGLEGAAGASAAGLNLLPLQTRFGGSKALRQRQAVAHWPTAESCPIEGFELH
RGSTIALEPLQALCQEEGLGWVQGQVAGSYLHGLLENGRWRRQWLNQLRRRKQLPELAEDQGHHSLQREELLDRLADAFE
ANVDLTPLISDP

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBQ_SYNR3 (A5GUP3)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001227955.1
- ProteinModelPortal:   A5GUP3
- STRING:   A5GUP3
- GeneID:   5157898
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_1699
- eggNOG:   COG1492
- HOGENOM:   HBG302271
- OMA:   AHTDLNP
- ProtClustDB:   PRK00784
- HAMAP:   MF_00028
- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00313

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: 6.3.5.10

Molecular weight: Translated: 53928; Mature: 53797

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS51274 GATASE_COBBQ

Important sites: ACT_SITE 336-336 ACT_SITE 433-433

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPTPLMVLGTSSGAGKSLMTAALCRVLKRRGEQPLPFKGQNMSNNAWVDQSGGEMAYS
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHH
QALQSWAAGLEPNCAMNPVLLKPQGNSTSEVIHGGESVGMARAETYYQEWFKPGWLAIRQ
HHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHCCCCHHCHHHHHHHHHHHCCCHHHHHHH
GLEQLRQQHPHGRLVLEGAGSPVEVNLQHRDLTNLRLAQYLRARCLLVADIERGGVFAQL
HHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEECCCCCHHHHH
VGTLQLLRPVERPLVKGLLINRFRGRQELFDPGVSWLSDNTGVPVLGVMPWLDELFPPED
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHCCCCCCCCEEHHHHHHHHCCCCC
SLDLLERRGRKANAELEIAVLRLPSLSNFSDLDPLEAEPSVQLRWVQPGEALGQPDAVVL
CHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHCCCCEEEE
PGSKQTLRDLKALQASGLARELQRFSAGGGAVLGICGGLQMLGRELLDPDGLEGAAGASA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AGLNLLPLQTRFGGSKALRQRQAVAHWPTAESCPIEGFELHRGSTIALEPLQALCQEEGL
CCCEEEEEHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEHHHHHHHHHHCCC
GWVQGQVAGSYLHGLLENGRWRRQWLNQLRRRKQLPELAEDQGHHSLQREELLDRLADAF
CEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHH
EANVDLTPLISDP
HCCCCCCCCCCCC
>Mature Secondary Structure 
TPPTPLMVLGTSSGAGKSLMTAALCRVLKRRGEQPLPFKGQNMSNNAWVDQSGGEMAYS
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHH
QALQSWAAGLEPNCAMNPVLLKPQGNSTSEVIHGGESVGMARAETYYQEWFKPGWLAIRQ
HHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHCCCCHHCHHHHHHHHHHHCCCHHHHHHH
GLEQLRQQHPHGRLVLEGAGSPVEVNLQHRDLTNLRLAQYLRARCLLVADIERGGVFAQL
HHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEECCCCCHHHHH
VGTLQLLRPVERPLVKGLLINRFRGRQELFDPGVSWLSDNTGVPVLGVMPWLDELFPPED
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHCCCCCCCCEEHHHHHHHHCCCCC
SLDLLERRGRKANAELEIAVLRLPSLSNFSDLDPLEAEPSVQLRWVQPGEALGQPDAVVL
CHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHCCCCEEEE
PGSKQTLRDLKALQASGLARELQRFSAGGGAVLGICGGLQMLGRELLDPDGLEGAAGASA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AGLNLLPLQTRFGGSKALRQRQAVAHWPTAESCPIEGFELHRGSTIALEPLQALCQEEGL
CCCEEEEEHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEHHHHHHHHHHCCC
GWVQGQVAGSYLHGLLENGRWRRQWLNQLRRRKQLPELAEDQGHHSLQREELLDRLADAF
CEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHH
EANVDLTPLISDP
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA