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The map label for this gene is trpF [H]

Identifier: 148242679

GI number: 148242679

Start: 1395418

End: 1396071

Strand: Direct

Name: trpF [H]

Synonym: SynRCC307_1580

Alternate gene names: 148242679

Gene position: 1395418-1396071 (Clockwise)

Preceding gene: 148242677

Following gene: 148242680

Centisome position: 62.72

GC content: 66.21

Gene sequence:

>654_bases
ATGGCTGCACAGCTGAAAATCTGCGGACTGATGCAACCGCCGCAAGCGGCGGCTGTGGCAGGGCTCGGCGCCAATGCCAT
CGGGGTGATCGCTGCTCGCCGCTCCGCCCGCTTTTTAGAACCAGCACAGCGGCCAGCCCTCTGGGAGGCCGTGGCAGGCA
CCAACCCCAACTGCTGCCGGGTGCTGGTGGTGGTCAATCCCAGCGACAGCGAGCTGGAGAGTTTGCGGCCTGAGCAGGGC
CATCAACTGCTGCAGCTGCACGGCGAAGAAACGCCAGAGCGCTGCCAGCAACTGCGTGATGAGCTGGGCTTACCCCTGTG
GAAAGCCCTGCGAATCCGCAGCGCCGCTGACCTCCAACAAGCCCAGGCCTACAGCGCCGTGGTGGATGGCCTGTTGCTCG
ATGCCTGGAGTAACTCGGCCCATGGCGGCACGGGCGAGCGCTTGCCGCTGCAATGGTTGCAAGGGTTTCAGCCGCTGTTG
CCCTGGTGGCTCGCCGGCGGGCTCGGCCCCAGCAATGCGCGCAGCGCCCTTGATCAACTGGCGCAGCAGGGGCTGACGCC
CACGGGGCTCGATGCCAGCAGCGGCGTGGAGCAAGCGCCCGGACTGAAAGATTTGCAGCTGGTGGAGGCGCTCATCAAAG
CCGTTCACGGCTGA

Upstream 100 bases:

>100_bases
CGGAATTCCGGCCAGGCTCATCACCTTCCAGCCTTGGCCCTGTGGGGCGTTGCTCACCTGCTTGCCCCCTTTCGACAACC
ACCATCCTAGAAACGCAGTC

Downstream 100 bases:

>100_bases
AATGCGCACAATTCAGCTAGTTGCTTTGCCGCCATGCCGGCTCCATGGCTGTTGGCCCAAGGACTGCTGATGGGTTGTCA
GTTGATCGGCGGTCAACTGG

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAAQLKICGLMQPPQAAAVAGLGANAIGVIAARRSARFLEPAQRPALWEAVAGTNPNCCRVLVVVNPSDSELESLRPEQG
HQLLQLHGEETPERCQQLRDELGLPLWKALRIRSAADLQQAQAYSAVVDGLLLDAWSNSAHGGTGERLPLQWLQGFQPLL
PWWLAGGLGPSNARSALDQLAQQGLTPTGLDASSGVEQAPGLKDLQLVEALIKAVHG

Sequences:

>Translated_217_residues
MAAQLKICGLMQPPQAAAVAGLGANAIGVIAARRSARFLEPAQRPALWEAVAGTNPNCCRVLVVVNPSDSELESLRPEQG
HQLLQLHGEETPERCQQLRDELGLPLWKALRIRSAADLQQAQAYSAVVDGLLLDAWSNSAHGGTGERLPLQWLQGFQPLL
PWWLAGGLGPSNARSALDQLAQQGLTPTGLDASSGVEQAPGLKDLQLVEALIKAVHG
>Mature_216_residues
AAQLKICGLMQPPQAAAVAGLGANAIGVIAARRSARFLEPAQRPALWEAVAGTNPNCCRVLVVVNPSDSELESLRPEQGH
QLLQLHGEETPERCQQLRDELGLPLWKALRIRSAADLQQAQAYSAVVDGLLLDAWSNSAHGGTGERLPLQWLQGFQPLLP
WWLAGGLGPSNARSALDQLAQQGLTPTGLDASSGVEQAPGLKDLQLVEALIKAVHG

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 23046; Mature: 22914

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQLKICGLMQPPQAAAVAGLGANAIGVIAARRSARFLEPAQRPALWEAVAGTNPNCCR
CCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCHHHCCHHHHHHCCCCCCCEE
VLVVVNPSDSELESLRPEQGHQLLQLHGEETPERCQQLRDELGLPLWKALRIRSAADLQQ
EEEEECCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AQAYSAVVDGLLLDAWSNSAHGGTGERLPLQWLQGFQPLLPWWLAGGLGPSNARSALDQL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHH
AQQGLTPTGLDASSGVEQAPGLKDLQLVEALIKAVHG
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAQLKICGLMQPPQAAAVAGLGANAIGVIAARRSARFLEPAQRPALWEAVAGTNPNCCR
CCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCHHHCCHHHHHHCCCCCCCEE
VLVVVNPSDSELESLRPEQGHQLLQLHGEETPERCQQLRDELGLPLWKALRIRSAADLQQ
EEEEECCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AQAYSAVVDGLLLDAWSNSAHGGTGERLPLQWLQGFQPLLPWWLAGGLGPSNARSALDQL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHH
AQQGLTPTGLDASSGVEQAPGLKDLQLVEALIKAVHG
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA