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The map label for this gene is crtH [H]

Identifier: 148242641

GI number: 148242641

Start: 1359527

End: 1361074

Strand: Direct

Name: crtH [H]

Synonym: SynRCC307_1542

Alternate gene names: 148242641

Gene position: 1359527-1361074 (Clockwise)

Preceding gene: 148242640

Following gene: 148242644

Centisome position: 61.1

GC content: 62.27

Gene sequence:

>1548_bases
GTGAGCAGCAGCCCGGATTGGGACGTGATCGTGATCGGCGCCGGGATTGGCGGCCTGGTTACCGCCAGCCAACTGGCAGC
CAAAGGGGCCAAGGTGCTGGTGCTGGAGCGCTATTTGATTCCTGGAGGTAGCGGCGGCAGTTTCAAACGGGCCGGCTACA
CCTTCGATGTGGGCGCCTCCATGATTTTTGGCTTCGGCCAAAAAGGCCATACCAACCTGCTGACCAGGGCCCTCGCCGAT
GTGGGGGAGCACTGCGACACCATCGCTGACCCGGTGCAGCTGGAATATCACTTGCCAGGCGGCCTGAACGTGGCCGTCGA
TCGCAATTACGAGAGCTTTGTCGAACGGCTGAGCAGCCTGTTTCCCCATGAAGCCAAAGGGATCCGCGCCTTCTATGACA
CCTGTTGGCAAGTGTTCCGCTGCCTCGATGCGATGCCGCTGCTCTCGCTCGAGGATCCGGCCTATCTCGCCAAGGTGTTT
TTCAGGGCTCCACTGGCTTGCCTAGGGCTTGCCCGCTGGCTGCCGTTCAATGTCGGCGATGTGGCCCGACAACACATCAA
CGATCCCCAGCTGCTCCAATTCATTGACATGGAGTGCTTCTGCTGGTCGGTGATGCCAGCAGATCTCACCCCGATGATCA
ATGCCGGCATGGTGTTTTCCGATCGCCATGCCGGCGGCATCAACTACCCCAAAGGCGGCGTTGGCACGATTGCCTGCAGG
TTGGTGAGTGGCCTCGAACGCCACGGCGGCCAGATCCGCTACAAGGCCCGTGTCACGCGCGTGCTGATGGACGGCAGCCA
AGCCGTTGGCGTTGAACTCGCCGATGGCGAGACAATCCATGCTCGACGCGTGGTCAGCAATGCCACCCGTTGGGACACCT
TCAGTGGGGAAGGTTCAGCCAAAGCGCCGCTGGTGGATGCCGATCACACACCTGCACGGGAGGCGCGTTGGCGCAAGCGC
TACAAGGCCTCGCCCTCGTTCCTCTCGCTGCACCTGGGAATCGATGCCGCATTGGTGCCCAGCGGTTTCCACTGCCACCA
CCTGCTGCTGGAGGACTGGCAGGCCATGGAAGACGAGCAGGGAGTGATCTTTGTGTCGATGCCCAGCCTTCTGGATCCTG
AGCTGGCCCCCAGCGGTCGGCACATCTTGCACTGCTTCACGCCTTCGGCAATGGAGCACTGGCAAGGCCTGGGGCCAGAG
GCCTACAAGGCCAAAAAACAGGCGGATGCCGACCGCTTAATCCAACGCCTCGAGACCTTGCTGTTGCCTGGCCTCAGTGG
CAGCATCCATCACCGCGAAGTGGGGACCCCGCGCAGCCATCGCCGCTTCCTTGGCCGTCACCAAGGCAGCTATGGCCCGA
TCCCAGCGCTGCGGCTGCCCGGCCTGCTGCCGATGCCGTTCAACCGCACCGGCGTCGATGGCCTCTACTGCGTTGGCGAT
TCCTGCTTCCCGGGGCAAGGGCTCAATGCCGTGGCCTTCAGTGGCTTTGCTTGTGCCCATCGGATCGGTGCTGATCTAGG
GCTCAATCCCTGGGCTTTACCCCAATGA

Upstream 100 bases:

>100_bases
ACAAACGCCGCCGCTACGGGGCCTACCGCGATCGGGCCCTGGCCGACCTCGCCCCCTTCAGCTCAGCCCCTAAGGTCGCC
GAAGCCACTGCAGCGGCCCT

Downstream 100 bases:

>100_bases
CGCCAGGGCCCCATCGCGCAGGTTGAGGTAGATCGCCCCGAGACCCTTGGTGAGAAATTCCACGCCAATGGCCAGGGTGA
ACAGGCCCATCAGCTTGATG

Product: carotenoid isomerase

Products: H+; Nicotinamide adenine dinucleotide; Nicotinamide adenine dinucleotide phosphate - reduced [C]

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MSSSPDWDVIVIGAGIGGLVTASQLAAKGAKVLVLERYLIPGGSGGSFKRAGYTFDVGASMIFGFGQKGHTNLLTRALAD
VGEHCDTIADPVQLEYHLPGGLNVAVDRNYESFVERLSSLFPHEAKGIRAFYDTCWQVFRCLDAMPLLSLEDPAYLAKVF
FRAPLACLGLARWLPFNVGDVARQHINDPQLLQFIDMECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGGVGTIACR
LVSGLERHGGQIRYKARVTRVLMDGSQAVGVELADGETIHARRVVSNATRWDTFSGEGSAKAPLVDADHTPAREARWRKR
YKASPSFLSLHLGIDAALVPSGFHCHHLLLEDWQAMEDEQGVIFVSMPSLLDPELAPSGRHILHCFTPSAMEHWQGLGPE
AYKAKKQADADRLIQRLETLLLPGLSGSIHHREVGTPRSHRRFLGRHQGSYGPIPALRLPGLLPMPFNRTGVDGLYCVGD
SCFPGQGLNAVAFSGFACAHRIGADLGLNPWALPQ

Sequences:

>Translated_515_residues
MSSSPDWDVIVIGAGIGGLVTASQLAAKGAKVLVLERYLIPGGSGGSFKRAGYTFDVGASMIFGFGQKGHTNLLTRALAD
VGEHCDTIADPVQLEYHLPGGLNVAVDRNYESFVERLSSLFPHEAKGIRAFYDTCWQVFRCLDAMPLLSLEDPAYLAKVF
FRAPLACLGLARWLPFNVGDVARQHINDPQLLQFIDMECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGGVGTIACR
LVSGLERHGGQIRYKARVTRVLMDGSQAVGVELADGETIHARRVVSNATRWDTFSGEGSAKAPLVDADHTPAREARWRKR
YKASPSFLSLHLGIDAALVPSGFHCHHLLLEDWQAMEDEQGVIFVSMPSLLDPELAPSGRHILHCFTPSAMEHWQGLGPE
AYKAKKQADADRLIQRLETLLLPGLSGSIHHREVGTPRSHRRFLGRHQGSYGPIPALRLPGLLPMPFNRTGVDGLYCVGD
SCFPGQGLNAVAFSGFACAHRIGADLGLNPWALPQ
>Mature_514_residues
SSSPDWDVIVIGAGIGGLVTASQLAAKGAKVLVLERYLIPGGSGGSFKRAGYTFDVGASMIFGFGQKGHTNLLTRALADV
GEHCDTIADPVQLEYHLPGGLNVAVDRNYESFVERLSSLFPHEAKGIRAFYDTCWQVFRCLDAMPLLSLEDPAYLAKVFF
RAPLACLGLARWLPFNVGDVARQHINDPQLLQFIDMECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGGVGTIACRL
VSGLERHGGQIRYKARVTRVLMDGSQAVGVELADGETIHARRVVSNATRWDTFSGEGSAKAPLVDADHTPAREARWRKRY
KASPSFLSLHLGIDAALVPSGFHCHHLLLEDWQAMEDEQGVIFVSMPSLLDPELAPSGRHILHCFTPSAMEHWQGLGPEA
YKAKKQADADRLIQRLETLLLPGLSGSIHHREVGTPRSHRRFLGRHQGSYGPIPALRLPGLLPMPFNRTGVDGLYCVGDS
CFPGQGLNAVAFSGFACAHRIGADLGLNPWALPQ

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: 1.6.1.1 [C]

Molecular weight: Translated: 56051; Mature: 55920

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSPDWDVIVIGAGIGGLVTASQLAAKGAKVLVLERYLIPGGSGGSFKRAGYTFDVGAS
CCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEEEECCHH
MIFGFGQKGHTNLLTRALADVGEHCDTIADPVQLEYHLPGGLNVAVDRNYESFVERLSSL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCHHHHHHHHHHH
FPHEAKGIRAFYDTCWQVFRCLDAMPLLSLEDPAYLAKVFFRAPLACLGLARWLPFNVGD
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VARQHINDPQLLQFIDMECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGGVGTIACR
HHHHHCCCHHHHHHHCHHHEEEECCCCCCCCHHCCCEEEECCCCCCCCCCCCCHHHHHHH
LVSGLERHGGQIRYKARVTRVLMDGSQAVGVELADGETIHARRVVSNATRWDTFSGEGSA
HHHHHHHCCCEEEEHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHCCCCCCCCCCCCCC
KAPLVDADHTPAREARWRKRYKASPSFLSLHLGIDAALVPSGFHCHHLLLEDWQAMEDEQ
CCCEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHCCCCC
GVIFVSMPSLLDPELAPSGRHILHCFTPSAMEHWQGLGPEAYKAKKQADADRLIQRLETL
CEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
LLPGLSGSIHHREVGTPRSHRRFLGRHQGSYGPIPALRLPGLLPMPFNRTGVDGLYCVGD
HCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEECC
SCFPGQGLNAVAFSGFACAHRIGADLGLNPWALPQ
CCCCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SSSPDWDVIVIGAGIGGLVTASQLAAKGAKVLVLERYLIPGGSGGSFKRAGYTFDVGAS
CCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEEEECCHH
MIFGFGQKGHTNLLTRALADVGEHCDTIADPVQLEYHLPGGLNVAVDRNYESFVERLSSL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCHHHHHHHHHHH
FPHEAKGIRAFYDTCWQVFRCLDAMPLLSLEDPAYLAKVFFRAPLACLGLARWLPFNVGD
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VARQHINDPQLLQFIDMECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGGVGTIACR
HHHHHCCCHHHHHHHCHHHEEEECCCCCCCCHHCCCEEEECCCCCCCCCCCCCHHHHHHH
LVSGLERHGGQIRYKARVTRVLMDGSQAVGVELADGETIHARRVVSNATRWDTFSGEGSA
HHHHHHHCCCEEEEHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHCCCCCCCCCCCCCC
KAPLVDADHTPAREARWRKRYKASPSFLSLHLGIDAALVPSGFHCHHLLLEDWQAMEDEQ
CCCEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCHHHHHHHHHHHCCCCC
GVIFVSMPSLLDPELAPSGRHILHCFTPSAMEHWQGLGPEAYKAKKQADADRLIQRLETL
CEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
LLPGLSGSIHHREVGTPRSHRRFLGRHQGSYGPIPALRLPGLLPMPFNRTGVDGLYCVGD
HCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEECC
SCFPGQGLNAVAFSGFACAHRIGADLGLNPWALPQ
CCCCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: 2'-AMP; FAD; p-Hydroxymercuribenzoate [C]

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H+; Nicotinamide adenine dinucleotide - reduced; Nicotinamide adenine dinucleotide phosphate [C]

Specific reaction: (2) H+ (Extracellular) + Nicotinamide adenine dinucleotide - reduced + Nicotinamide adenine dinucleotide phosphate --> (2) H+ + Nicotinamide adenine dinucleotide + Nicotinamide adenine dinucleotide phosphate - reduced [C]

General reaction: Redox reaction [C]

Inhibitor: p-Hydroxy mercuribenzoate reducedsubstrate, [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592436 [H]