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The map label for this gene is ruvA

Identifier: 148242421

GI number: 148242421

Start: 1171301

End: 1171927

Strand: Direct

Name: ruvA

Synonym: SynRCC307_1322

Alternate gene names: 148242421

Gene position: 1171301-1171927 (Clockwise)

Preceding gene: 148242417

Following gene: 148242422

Centisome position: 52.64

GC content: 62.52

Gene sequence:

>627_bases
ATGATCGGTTGGTTGCATGGAACGATCGGTGATCGCTGGCAAGAGGGCAACCGCTGCTGGCTTCTGTTGATCTGCGGGCC
AGTTGGTTACGAGCTGCAGGTGAGCGAGAGCCTCTGGCGAGGCACCGCTTTGGAGAGCCCAACGACTGTCCATACCCATC
TGCAGCAACGCGAGGACGGCCAACAGCTCTATGGCTTTGAAACCAAAGCCGATCGCAACCTGTTCCGCTTGTTGATCAGT
GTCAATGGCGTGGGTCCGCAGGTCGCCCTGGGACTGATCTCAGGTTTGGGCGCGGTGAGCTTGCTGCAAGCAATGGCAGC
AGAAGACGTCAAAGTGCTTTGCCAAGCGCCCGGCGTTGGCAAACGCACCGCCGAGCGGCTCAGCCTGGAATGGCGCTCAC
GGCTGCAAGAGCGCTGGCAACAGCAGGGGGGATCCACACCGCTGCGCCTGGTGGAGCCGGTGGCGGAAAGCCGGGAACTG
CGCGCCACCCTGGAAGCCCTCGGCTATGGGCCAGAAGAAGTGAGCGCGGCGGTAGCCCAAGCGGGCAGCCAAGGCCTTGA
TCCGGAACAACCCATGGAGGAGTGGTTACGGCATTGCTTGGCGTGGCTGAGCCGTCAAGCGGGCTAG

Upstream 100 bases:

>100_bases
AAGCGGGCAACAGCACCAGCATCAACAACAGAGCCATTCCCACCACAAGGCGGCGCAGCACGGCGATCAACGGCAACATG
GCAGCACTTCTAGGCACAGC

Downstream 100 bases:

>100_bases
AGAACCGCGAACGGTATGCTTTTGGATTACACGAGCTGGGTCTCCCCTCCCGCATGCCCCTCAACACCGAGAAGAAACAA
GAACTGATCAACTCCCACCA

Product: Holliday junction resolvasome DNA-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MIGWLHGTIGDRWQEGNRCWLLLICGPVGYELQVSESLWRGTALESPTTVHTHLQQREDGQQLYGFETKADRNLFRLLIS
VNGVGPQVALGLISGLGAVSLLQAMAAEDVKVLCQAPGVGKRTAERLSLEWRSRLQERWQQQGGSTPLRLVEPVAESREL
RATLEALGYGPEEVSAAVAQAGSQGLDPEQPMEEWLRHCLAWLSRQAG

Sequences:

>Translated_208_residues
MIGWLHGTIGDRWQEGNRCWLLLICGPVGYELQVSESLWRGTALESPTTVHTHLQQREDGQQLYGFETKADRNLFRLLIS
VNGVGPQVALGLISGLGAVSLLQAMAAEDVKVLCQAPGVGKRTAERLSLEWRSRLQERWQQQGGSTPLRLVEPVAESREL
RATLEALGYGPEEVSAAVAQAGSQGLDPEQPMEEWLRHCLAWLSRQAG
>Mature_208_residues
MIGWLHGTIGDRWQEGNRCWLLLICGPVGYELQVSESLWRGTALESPTTVHTHLQQREDGQQLYGFETKADRNLFRLLIS
VNGVGPQVALGLISGLGAVSLLQAMAAEDVKVLCQAPGVGKRTAERLSLEWRSRLQERWQQQGGSTPLRLVEPVAESREL
RATLEALGYGPEEVSAAVAQAGSQGLDPEQPMEEWLRHCLAWLSRQAG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=213, Percent_Identity=36.150234741784, Blast_Score=110, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_SYNR3 (A5GTL6)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001227578.1
- ProteinModelPortal:   A5GTL6
- SMR:   A5GTL6
- STRING:   A5GTL6
- GeneID:   5157998
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_1322
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   ISWINGD
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like

EC number: =3.6.4.12

Molecular weight: Translated: 22935; Mature: 22935

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGWLHGTIGDRWQEGNRCWLLLICGPVGYELQVSESLWRGTALESPTTVHTHLQQREDG
CCCEEECCCCHHHCCCCCEEEEEEECCCCCEEEEHHHHHCCCCCCCCCHHHHHHHHHCCC
QQLYGFETKADRNLFRLLISVNGVGPQVALGLISGLGAVSLLQAMAAEDVKVLCQAPGVG
HHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KRTAERLSLEWRSRLQERWQQQGGSTPLRLVEPVAESRELRATLEALGYGPEEVSAAVAQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGSQGLDPEQPMEEWLRHCLAWLSRQAG
HCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGWLHGTIGDRWQEGNRCWLLLICGPVGYELQVSESLWRGTALESPTTVHTHLQQREDG
CCCEEECCCCHHHCCCCCEEEEEEECCCCCEEEEHHHHHCCCCCCCCCHHHHHHHHHCCC
QQLYGFETKADRNLFRLLISVNGVGPQVALGLISGLGAVSLLQAMAAEDVKVLCQAPGVG
HHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KRTAERLSLEWRSRLQERWQQQGGSTPLRLVEPVAESRELRATLEALGYGPEEVSAAVAQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGSQGLDPEQPMEEWLRHCLAWLSRQAG
HCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA