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The map label for this gene is lspA

Identifier: 148242388

GI number: 148242388

Start: 1142939

End: 1143394

Strand: Direct

Name: lspA

Synonym: SynRCC307_1289

Alternate gene names: 148242388

Gene position: 1142939-1143394 (Clockwise)

Preceding gene: 148242387

Following gene: 148242389

Centisome position: 51.37

GC content: 59.87

Gene sequence:

>456_bases
ATGGCTGGCAAACGTTTCTGGATCCTGCTGAGTGCTGCTGGGCTGTTGCTGCTGGATCAGCTCAGTAAGCAGTGGTGGCT
GCAAAACCTGCCACCTGGCGTCAGCCAGAGCTGGATTCCTGGACTGCTCAACCTGAGGCTGGTCTGGAACGATGGCGCCG
CCTTCAGCCTGTTTCGCAGTGGCTCGCAGTGGCTGGGCTGGATCAGCCTGCTAGTCAGCGTTGGCCTGTTGATCTGGATT
GGGCGCCGTGGTCGGCAGTGGTCCCGCTGGCAAGCCGCAGCTGCCGCATTCCTGCTGGCAGGAAGCGTCGGCAATGGCAT
CGATCGCTGGCGCTATGGAGCGGTGATCGATGGCCTTGAACTGGTGCCATTCTCATTTCCCGTCTTCAATTTGGCCGACG
TTGCGATCAACTTGGCCGTGTTGTGTCTGTTGATCGAAGCCATCCGCCAGCGATGA

Upstream 100 bases:

>100_bases
TTATGGACTGCTTCCCCTGGGAGGCCAGATCTTGCTCTGCGCAGTCGTTGCTGTGGTGAGCCGGCTGCTGCGACCACTGC
TGACGGTCAACCACTAGGTC

Downstream 100 bases:

>100_bases
GCCCATTCCTACGCCTTCACATCAACGGTGAACCCAGCAGGGAGATCCAGCTGCTGGGGGAGGTGTATCGACTGGGGCGC
GATCCCGACGCCGAAATCGT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MAGKRFWILLSAAGLLLLDQLSKQWWLQNLPPGVSQSWIPGLLNLRLVWNDGAAFSLFRSGSQWLGWISLLVSVGLLIWI
GRRGRQWSRWQAAAAAFLLAGSVGNGIDRWRYGAVIDGLELVPFSFPVFNLADVAINLAVLCLLIEAIRQR

Sequences:

>Translated_151_residues
MAGKRFWILLSAAGLLLLDQLSKQWWLQNLPPGVSQSWIPGLLNLRLVWNDGAAFSLFRSGSQWLGWISLLVSVGLLIWI
GRRGRQWSRWQAAAAAFLLAGSVGNGIDRWRYGAVIDGLELVPFSFPVFNLADVAINLAVLCLLIEAIRQR
>Mature_150_residues
AGKRFWILLSAAGLLLLDQLSKQWWLQNLPPGVSQSWIPGLLNLRLVWNDGAAFSLFRSGSQWLGWISLLVSVGLLIWIG
RRGRQWSRWQAAAAAFLLAGSVGNGIDRWRYGAVIDGLELVPFSFPVFNLADVAINLAVLCLLIEAIRQR

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LSPA_SYNR3 (A5GTI3)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001227545.1
- STRING:   A5GTI3
- MEROPS:   A08.001
- GeneID:   5156864
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_1289
- eggNOG:   COG0597
- HOGENOM:   HBG724422
- OMA:   PADIAIN
- GO:   GO:0006508
- HAMAP:   MF_00161
- InterPro:   IPR001872
- PRINTS:   PR00781
- TIGRFAMs:   TIGR00077

Pfam domain/function: PF01252 Peptidase_A8

EC number: =3.4.23.36

Molecular weight: Translated: 16827; Mature: 16696

Theoretical pI: Translated: 11.62; Mature: 11.62

Prosite motif: PS00855 SPASE_II

Important sites: ACT_SITE 108-108 ACT_SITE 133-133

Signals:

None

Transmembrane regions:

HASH(0x23c07148)-; HASH(0x23a3ab84)-; HASH(0x20fb8ef8)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKRFWILLSAAGLLLLDQLSKQWWLQNLPPGVSQSWIPGLLNLRLVWNDGAAFSLFRS
CCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEEECCCCHHHHHHC
GSQWLGWISLLVSVGLLIWIGRRGRQWSRWQAAAAAFLLAGSVGNGIDRWRYGAVIDGLE
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCE
LVPFSFPVFNLADVAINLAVLCLLIEAIRQR
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
AGKRFWILLSAAGLLLLDQLSKQWWLQNLPPGVSQSWIPGLLNLRLVWNDGAAFSLFRS
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEEECCCCHHHHHHC
GSQWLGWISLLVSVGLLIWIGRRGRQWSRWQAAAAAFLLAGSVGNGIDRWRYGAVIDGLE
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCE
LVPFSFPVFNLADVAINLAVLCLLIEAIRQR
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA