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The map label for this gene is metH [H]

Identifier: 148242308

GI number: 148242308

Start: 1067999

End: 1071589

Strand: Direct

Name: metH [H]

Synonym: SynRCC307_1209

Alternate gene names: 148242308

Gene position: 1067999-1071589 (Clockwise)

Preceding gene: 148242307

Following gene: 148242309

Centisome position: 48.0

GC content: 58.7

Gene sequence:

>3591_bases
GTGATGCACCGCTTTCTGGAGAGACTGCACGCTCCGGAGCGGCCAGTTCTCGTCTTCGATGGGGCGACGGGTACCTCGCT
CCAACAGATGGATCTTGGCCCCGATGATTTCGGTGGCGCTGCCCTGGAGGGCTGCAACGAAAACCTGGTGGTGACCAGGC
CGGATGCCGTGCAAGAGGTGCACCGGCAGTTCCTTGAGGCCGGTTGCGATGTGATTGAAACCGACACCTTCGGGGCCACC
TCGTTGGTGTTGGCTGAATACGACCTGCAGGACCAGACCTACGAGCTCAATGTCAAAGCGGCTCAACTGGCCCGTGAGAT
GGCCGATCGCTACAGCACCCCAGAGAAGCCGCGCTTTGTGGCCGGCTCCATGGGGCCCACCACGAAGCTGCCAACCCTGG
GGCATGTGGGCTTCGATGCGATGCGCGATTCCTTTGCCGAACAGGCCCGCGGCTTGCTGGCCGGCAATGTTGACCTGTTC
ATCATCGAAACCTGCCAAGACCCGCTGCAAATCAAGGCAGCCTTAGCTGGCCTTGAGCAGGCGTTTGCTGCCGCTGGCGA
GCGGCGGCCGGTGATGGTCAGCGTGACGATGGAAACCACCGGCACGATGTTGGTGGGCTCCGACATCGCCGCTGTGGTGG
CGATCCTCGAACCCTTCCCGATTGATGTGTTGGGCCTCAATTGCGCCACGGGCCCGGAGCAAATGAAAGAGCACGTGCGC
TACCTCAGCGCGCATGCTCCCTTTGTTGTGAGTTGCATCCCCAATGCCGGTTTGCCGGAAAACGTGGGGGGTGTGGCCCA
CTACCGGCTAACCCCGGTGGAAATGAAGATGGCGATGCACCACTTCATCGAAGACCTCGGGGTTCAGGTCATTGGTGGCT
GTTGCGGCACCACGCCAGCCCACATTGCTGCCCTGGCTGAGTTGGCCCAGGAGATGACCCCAGCGGAACGGCCGGTGCGC
ACGCCCCAGGCCCAACTCCAACGCCCCTTGTTGGGTGCTGAGGCATCGGCGGCCTCGATTTATGGGACGACGCCTTATCA
CCAGGACAACTCCTTTTTGATCATTGGTGAGCGGCTCAACGCCAGTGGCTCCAAGAAGGTGCGCGAGCTGCTGAACAGCG
AAGACTGGGATGGCCTGGTGGCTGTTGCTAGGGGCCAGGTCAAAGAGAATGCCCACGTGCTCGATGTCAACGTCGACTAT
GTCGGCCGTGACGGTGAGAAAGATATGCACGACTTGGTGAGCCGTTTGGTCACCAACGTCAACCTGCCGTTGATGCTCGA
CTCCACGGAATGGCAAAAGATGGAGGCCGGGCTGAAGGTGGCTGGTGGTAAGTGCCTGCTGAATTCCACCAACTACGAAG
ACGGCGACGAGCGCTTCTTCAAAGTGCTGGAGCTGGCTCGGACCTATGGCGCTGGTGTGGTGGTGGGCACCATCGATGAA
GAGGGAATGGCACGAACCGCCGATCGCAAGTTCGCCATTGCCCAACGCGCTTATCGAGATGCCGTGGAGTTCGGCATCCC
GGCCCATGAAATCTTTTACGACCCCCTGGCGTTACCGATTTCAACCGGCATCGAAGAAGACCGGCGCAATGGCTGCGAAA
CCATTGAAGCGATTCGGCGCATCATCACCGACTTGCCTGGAGTTCACGTCGTCCTCGGCGTGAGCAATATCAGCTTTGGT
CTCTCACCGGCTGCACGGATCACCTTGAACTCCGTGTTCCTGCATGACTGCTGTGAAGCCGGGATGGACGCCGCCATCGT
GAGCCCAGCCAAAATCCTGCCGCTGATGAAGATCAGCGATGAGCATCAACAGGTGTGCCGGGATCTGATCAACGACAACC
GTCGTTTTGAGGGCTCGGTTTGCATTTACGACCCCCTCACCGAACTCACCACGATGTTCGAAGGGGTGAGCACCAAAGAG
GCACGAGCCTCAGGCCCCTCATTGGCTGACTTGCCGGTCGAGGAACGGCTCAAACAACACATCATTGATGGTGAACGAAT
TGGCTTAGAGCCGGCCTTGGATGAAGGCCTGCAGAACTACAAACCCCTTCAGATCGTCAACACCTTTTTGCTCGATGGCA
TGAAGGTGGTGGGGGAATTGTTTGGTTCGGGCCAAATGCAACTTCCGTTTGTGCTGCAGAGCGCCGAAACCATGAAAAGC
GCTGTGGCTTATCTCGAGCCCCATATGGAGAAAACAGAAGGGGAAAGTTCAGGCAAGGCCAAATTCTTGATCGCCACGGT
GAAAGGCGACGTGCATGACATTGGCAAAAATCTGGTTGACATCATCCTCACCAATAACGGCTATGAGGTGGTCAACCTCG
GCATCAAACAGTCTGTTGATGCCATCATCGAAGCCCAGCAAACCCATCAGGCTGATTGCATTGCCATGAGCGGTCTGCTG
GTGAAATCGACGGCCTTCATGAAGGACAACCTGCAGGCCTTCAATGACGCCGGCATCTCGGTCCCTGTAATTCTTGGCGG
AGCAGCCTTAACGCCACGCTTTGTGCAGAAGGACTGCCGTGAGGTTTATAACGGTCAAGTCATCTATGGCCGTGATGCGT
TCGCTGATCTGCGCTTTATGGACGCGCTGGTGGATGCGAAAAAAGGTGGTGAGTGGAGTGACACCGAGGGTTTCCTTGGA
GCCGTTCCCGAGGGTCTGGGGCTCAACGGCGATGCCCATAGCGATTCAGCAAGCTCGGATGGCGCAGCCAGCGAGCCCAC
CGAGGAGAAGCCATCACTGCCTGTGAGCCTTGAGCGGTCCGCTGCTGTGCCAGAAGAACCGGCACTAGAGCCTCCCTTCT
GGGGGACCAAGGTGCTCAGCGAGCAGGACATGGATCTGGAGGAGGTGTTTGGCTACCTCGATCGCAACGCGCTGTTTGCA
GGCCAGTGGCAAATGCGCAAAAGCAAGGACCAAAGCCGCGAGGAGTATGAGCAACAACTCCGCGATAAGGCTGAGCCGGT
GTTGCAGGAGTGGTTGCAACGGGCCCGCAGCGAGAAGCTGCTGACGCCGCGTGTGGCCTATGGGTATTTCCCGTGCGGAC
GCGATGGCAATGCCGTTGTGGTGTTCGATCCCAACGACACCACGCGTGAGCTGGGACGCTTTGAGTTGCCACGGCAACGC
TCGGGCAACACCTACTGCATCGCTGATTTTTATCGGGATCTCAGCAGCAATGGCGAACCCACCGATATGTTGCCCATGCA
AGCGGTGACCATGGGTGAGAAGGCCAGTGCTTTTGCCAAGGAGCTCTTCCAAGCAGATCGCTACAGCGATTACCTCTACT
TCCACGGCTTGGGTGTGCAGATGGCTGAAGCCCTTGCTGAGTGGACCCACGCGCGCATTCGCGCTGAGCTTGGCTTCGCT
GCCGATGAGCCTGAAGCCCTGCGGGATGTGTTGGCCCAGCGCTACCGAGGCAGCCGGTATTCCTTTGGCTACCCCGCCTG
TCCCAACGTCGCCGATTCAAGGCCTCAGCTGGATTGGCTTGAGGCTGATCGCATTGGCCTGTCCATGGATGACAGCGATC
AATTGGAGCCAGAACAGAGCACAACCGCCCTGGTGGCCCTGCACAGCCAGGCGCGCTATTTCAGCGCTTGA

Upstream 100 bases:

>100_bases
CTGATCGGCCGGTCATGGATGCCTTGCGCGAGCGCATCACCGCCATTACCGAGGGGCGAGACCCTAACTTTGAGCACTGG
GTGACGCGGATTCGGATTAA

Downstream 100 bases:

>100_bases
TTGTGAGAGCCTGAGCGCTTGCTGCGCTGAATCAATGGCGATTGCTGGACCTGGCGGCGTTGATGACGCCATTGCCGCTG
GCCTGGACCTCGATGGAACA

Product: methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase)

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1196; Mature: 1196

Protein sequence:

>1196_residues
MMHRFLERLHAPERPVLVFDGATGTSLQQMDLGPDDFGGAALEGCNENLVVTRPDAVQEVHRQFLEAGCDVIETDTFGAT
SLVLAEYDLQDQTYELNVKAAQLAREMADRYSTPEKPRFVAGSMGPTTKLPTLGHVGFDAMRDSFAEQARGLLAGNVDLF
IIETCQDPLQIKAALAGLEQAFAAAGERRPVMVSVTMETTGTMLVGSDIAAVVAILEPFPIDVLGLNCATGPEQMKEHVR
YLSAHAPFVVSCIPNAGLPENVGGVAHYRLTPVEMKMAMHHFIEDLGVQVIGGCCGTTPAHIAALAELAQEMTPAERPVR
TPQAQLQRPLLGAEASAASIYGTTPYHQDNSFLIIGERLNASGSKKVRELLNSEDWDGLVAVARGQVKENAHVLDVNVDY
VGRDGEKDMHDLVSRLVTNVNLPLMLDSTEWQKMEAGLKVAGGKCLLNSTNYEDGDERFFKVLELARTYGAGVVVGTIDE
EGMARTADRKFAIAQRAYRDAVEFGIPAHEIFYDPLALPISTGIEEDRRNGCETIEAIRRIITDLPGVHVVLGVSNISFG
LSPAARITLNSVFLHDCCEAGMDAAIVSPAKILPLMKISDEHQQVCRDLINDNRRFEGSVCIYDPLTELTTMFEGVSTKE
ARASGPSLADLPVEERLKQHIIDGERIGLEPALDEGLQNYKPLQIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKS
AVAYLEPHMEKTEGESSGKAKFLIATVKGDVHDIGKNLVDIILTNNGYEVVNLGIKQSVDAIIEAQQTHQADCIAMSGLL
VKSTAFMKDNLQAFNDAGISVPVILGGAALTPRFVQKDCREVYNGQVIYGRDAFADLRFMDALVDAKKGGEWSDTEGFLG
AVPEGLGLNGDAHSDSASSDGAASEPTEEKPSLPVSLERSAAVPEEPALEPPFWGTKVLSEQDMDLEEVFGYLDRNALFA
GQWQMRKSKDQSREEYEQQLRDKAEPVLQEWLQRARSEKLLTPRVAYGYFPCGRDGNAVVVFDPNDTTRELGRFELPRQR
SGNTYCIADFYRDLSSNGEPTDMLPMQAVTMGEKASAFAKELFQADRYSDYLYFHGLGVQMAEALAEWTHARIRAELGFA
ADEPEALRDVLAQRYRGSRYSFGYPACPNVADSRPQLDWLEADRIGLSMDDSDQLEPEQSTTALVALHSQARYFSA

Sequences:

>Translated_1196_residues
MMHRFLERLHAPERPVLVFDGATGTSLQQMDLGPDDFGGAALEGCNENLVVTRPDAVQEVHRQFLEAGCDVIETDTFGAT
SLVLAEYDLQDQTYELNVKAAQLAREMADRYSTPEKPRFVAGSMGPTTKLPTLGHVGFDAMRDSFAEQARGLLAGNVDLF
IIETCQDPLQIKAALAGLEQAFAAAGERRPVMVSVTMETTGTMLVGSDIAAVVAILEPFPIDVLGLNCATGPEQMKEHVR
YLSAHAPFVVSCIPNAGLPENVGGVAHYRLTPVEMKMAMHHFIEDLGVQVIGGCCGTTPAHIAALAELAQEMTPAERPVR
TPQAQLQRPLLGAEASAASIYGTTPYHQDNSFLIIGERLNASGSKKVRELLNSEDWDGLVAVARGQVKENAHVLDVNVDY
VGRDGEKDMHDLVSRLVTNVNLPLMLDSTEWQKMEAGLKVAGGKCLLNSTNYEDGDERFFKVLELARTYGAGVVVGTIDE
EGMARTADRKFAIAQRAYRDAVEFGIPAHEIFYDPLALPISTGIEEDRRNGCETIEAIRRIITDLPGVHVVLGVSNISFG
LSPAARITLNSVFLHDCCEAGMDAAIVSPAKILPLMKISDEHQQVCRDLINDNRRFEGSVCIYDPLTELTTMFEGVSTKE
ARASGPSLADLPVEERLKQHIIDGERIGLEPALDEGLQNYKPLQIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKS
AVAYLEPHMEKTEGESSGKAKFLIATVKGDVHDIGKNLVDIILTNNGYEVVNLGIKQSVDAIIEAQQTHQADCIAMSGLL
VKSTAFMKDNLQAFNDAGISVPVILGGAALTPRFVQKDCREVYNGQVIYGRDAFADLRFMDALVDAKKGGEWSDTEGFLG
AVPEGLGLNGDAHSDSASSDGAASEPTEEKPSLPVSLERSAAVPEEPALEPPFWGTKVLSEQDMDLEEVFGYLDRNALFA
GQWQMRKSKDQSREEYEQQLRDKAEPVLQEWLQRARSEKLLTPRVAYGYFPCGRDGNAVVVFDPNDTTRELGRFELPRQR
SGNTYCIADFYRDLSSNGEPTDMLPMQAVTMGEKASAFAKELFQADRYSDYLYFHGLGVQMAEALAEWTHARIRAELGFA
ADEPEALRDVLAQRYRGSRYSFGYPACPNVADSRPQLDWLEADRIGLSMDDSDQLEPEQSTTALVALHSQARYFSA
>Mature_1196_residues
MMHRFLERLHAPERPVLVFDGATGTSLQQMDLGPDDFGGAALEGCNENLVVTRPDAVQEVHRQFLEAGCDVIETDTFGAT
SLVLAEYDLQDQTYELNVKAAQLAREMADRYSTPEKPRFVAGSMGPTTKLPTLGHVGFDAMRDSFAEQARGLLAGNVDLF
IIETCQDPLQIKAALAGLEQAFAAAGERRPVMVSVTMETTGTMLVGSDIAAVVAILEPFPIDVLGLNCATGPEQMKEHVR
YLSAHAPFVVSCIPNAGLPENVGGVAHYRLTPVEMKMAMHHFIEDLGVQVIGGCCGTTPAHIAALAELAQEMTPAERPVR
TPQAQLQRPLLGAEASAASIYGTTPYHQDNSFLIIGERLNASGSKKVRELLNSEDWDGLVAVARGQVKENAHVLDVNVDY
VGRDGEKDMHDLVSRLVTNVNLPLMLDSTEWQKMEAGLKVAGGKCLLNSTNYEDGDERFFKVLELARTYGAGVVVGTIDE
EGMARTADRKFAIAQRAYRDAVEFGIPAHEIFYDPLALPISTGIEEDRRNGCETIEAIRRIITDLPGVHVVLGVSNISFG
LSPAARITLNSVFLHDCCEAGMDAAIVSPAKILPLMKISDEHQQVCRDLINDNRRFEGSVCIYDPLTELTTMFEGVSTKE
ARASGPSLADLPVEERLKQHIIDGERIGLEPALDEGLQNYKPLQIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKS
AVAYLEPHMEKTEGESSGKAKFLIATVKGDVHDIGKNLVDIILTNNGYEVVNLGIKQSVDAIIEAQQTHQADCIAMSGLL
VKSTAFMKDNLQAFNDAGISVPVILGGAALTPRFVQKDCREVYNGQVIYGRDAFADLRFMDALVDAKKGGEWSDTEGFLG
AVPEGLGLNGDAHSDSASSDGAASEPTEEKPSLPVSLERSAAVPEEPALEPPFWGTKVLSEQDMDLEEVFGYLDRNALFA
GQWQMRKSKDQSREEYEQQLRDKAEPVLQEWLQRARSEKLLTPRVAYGYFPCGRDGNAVVVFDPNDTTRELGRFELPRQR
SGNTYCIADFYRDLSSNGEPTDMLPMQAVTMGEKASAFAKELFQADRYSDYLYFHGLGVQMAEALAEWTHARIRAELGFA
ADEPEALRDVLAQRYRGSRYSFGYPACPNVADSRPQLDWLEADRIGLSMDDSDQLEPEQSTTALVALHSQARYFSA

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1255, Percent_Identity=30.7569721115538, Blast_Score=506, Evalue=1e-143,
Organism=Homo sapiens, GI13162290, Length=339, Percent_Identity=27.7286135693215, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI1790450, Length=1247, Percent_Identity=31.4354450681636, Blast_Score=537, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17535405, Length=1244, Percent_Identity=33.1993569131833, Blast_Score=558, Evalue=1e-159,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 130911; Mature: 130911

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHRFLERLHAPERPVLVFDGATGTSLQQMDLGPDDFGGAALEGCNENLVVTRPDAVQEV
CHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCCCCCCCHHHHCCCCCEEEECCHHHHHH
HRQFLEAGCDVIETDTFGATSLVLAEYDLQDQTYELNVKAAQLAREMADRYSTPEKPRFV
HHHHHHCCCCEEECCCCCCEEEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCEE
AGSMGPTTKLPTLGHVGFDAMRDSFAEQARGLLAGNVDLFIIETCQDPLQIKAALAGLEQ
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHHHHH
AFAAAGERRPVMVSVTMETTGTMLVGSDIAAVVAILEPFPIDVLGLNCATGPEQMKEHVR
HHHHCCCCCCEEEEEEECCCCCEEECCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHH
YLSAHAPFVVSCIPNAGLPENVGGVAHYRLTPVEMKMAMHHFIEDLGVQVIGGCCGTTPA
HHHCCCCEEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHEECCCCCCCHH
HIAALAELAQEMTPAERPVRTPQAQLQRPLLGAEASAASIYGTTPYHQDNSFLIIGERLN
HHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCC
ASGSKKVRELLNSEDWDGLVAVARGQVKENAHVLDVNVDYVGRDGEKDMHDLVSRLVTNV
CCCHHHHHHHHCCCCCCCEEHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCC
NLPLMLDSTEWQKMEAGLKVAGGKCLLNSTNYEDGDERFFKVLELARTYGAGVVVGTIDE
CCEEEECCCHHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCC
EGMARTADRKFAIAQRAYRDAVEFGIPAHEIFYDPLALPISTGIEEDRRNGCETIEAIRR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCHHCCCCHHHHCCHHHHHHHHH
IITDLPGVHVVLGVSNISFGLSPAARITLNSVFLHDCCEAGMDAAIVSPAKILPLMKISD
HHHHCCCCEEEEEECCCCCCCCCCHHEEHHHHHHHHHHHCCCCEEECCHHHHCCHHHCCH
EHQQVCRDLINDNRRFEGSVCIYDPLTELTTMFEGVSTKEARASGPSLADLPVEERLKQH
HHHHHHHHHHCCCCEECCCEEEECCHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHH
IIDGERIGLEPALDEGLQNYKPLQIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKS
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
AVAYLEPHMEKTEGESSGKAKFLIATVKGDVHDIGKNLVDIILTNNGYEVVNLGIKQSVD
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHEEEEEEECCCCEEEECCHHHHHH
AIIEAQQTHQADCIAMSGLLVKSTAFMKDNLQAFNDAGISVPVILGGAALTPRFVQKDCR
HHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
EVYNGQVIYGRDAFADLRFMDALVDAKKGGEWSDTEGFLGAVPEGLGLNGDAHSDSASSD
HHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
GAASEPTEEKPSLPVSLERSAAVPEEPALEPPFWGTKVLSEQDMDLEEVFGYLDRNALFA
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHCCCCEEE
GQWQMRKSKDQSREEYEQQLRDKAEPVLQEWLQRARSEKLLTPRVAYGYFPCGRDGNAVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEE
VFDPNDTTRELGRFELPRQRSGNTYCIADFYRDLSSNGEPTDMLPMQAVTMGEKASAFAK
EECCCCCHHHHHCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHH
ELFQADRYSDYLYFHGLGVQMAEALAEWTHARIRAELGFAADEPEALRDVLAQRYRGSRY
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
SFGYPACPNVADSRPQLDWLEADRIGLSMDDSDQLEPEQSTTALVALHSQARYFSA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCEEEEEEHHHHHHCCC
>Mature Secondary Structure
MMHRFLERLHAPERPVLVFDGATGTSLQQMDLGPDDFGGAALEGCNENLVVTRPDAVQEV
CHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCCCCCCCHHHHCCCCCEEEECCHHHHHH
HRQFLEAGCDVIETDTFGATSLVLAEYDLQDQTYELNVKAAQLAREMADRYSTPEKPRFV
HHHHHHCCCCEEECCCCCCEEEEEEEECCCCCEEEECHHHHHHHHHHHHHCCCCCCCCEE
AGSMGPTTKLPTLGHVGFDAMRDSFAEQARGLLAGNVDLFIIETCQDPLQIKAALAGLEQ
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHHHHH
AFAAAGERRPVMVSVTMETTGTMLVGSDIAAVVAILEPFPIDVLGLNCATGPEQMKEHVR
HHHHCCCCCCEEEEEEECCCCCEEECCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHH
YLSAHAPFVVSCIPNAGLPENVGGVAHYRLTPVEMKMAMHHFIEDLGVQVIGGCCGTTPA
HHHCCCCEEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHEECCCCCCCHH
HIAALAELAQEMTPAERPVRTPQAQLQRPLLGAEASAASIYGTTPYHQDNSFLIIGERLN
HHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCC
ASGSKKVRELLNSEDWDGLVAVARGQVKENAHVLDVNVDYVGRDGEKDMHDLVSRLVTNV
CCCHHHHHHHHCCCCCCCEEHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCC
NLPLMLDSTEWQKMEAGLKVAGGKCLLNSTNYEDGDERFFKVLELARTYGAGVVVGTIDE
CCEEEECCCHHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCC
EGMARTADRKFAIAQRAYRDAVEFGIPAHEIFYDPLALPISTGIEEDRRNGCETIEAIRR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCHHCCCCHHHHCCHHHHHHHHH
IITDLPGVHVVLGVSNISFGLSPAARITLNSVFLHDCCEAGMDAAIVSPAKILPLMKISD
HHHHCCCCEEEEEECCCCCCCCCCHHEEHHHHHHHHHHHCCCCEEECCHHHHCCHHHCCH
EHQQVCRDLINDNRRFEGSVCIYDPLTELTTMFEGVSTKEARASGPSLADLPVEERLKQH
HHHHHHHHHHCCCCEECCCEEEECCHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHH
IIDGERIGLEPALDEGLQNYKPLQIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKS
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
AVAYLEPHMEKTEGESSGKAKFLIATVKGDVHDIGKNLVDIILTNNGYEVVNLGIKQSVD
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHEEEEEEECCCCEEEECCHHHHHH
AIIEAQQTHQADCIAMSGLLVKSTAFMKDNLQAFNDAGISVPVILGGAALTPRFVQKDCR
HHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHH
EVYNGQVIYGRDAFADLRFMDALVDAKKGGEWSDTEGFLGAVPEGLGLNGDAHSDSASSD
HHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCC
GAASEPTEEKPSLPVSLERSAAVPEEPALEPPFWGTKVLSEQDMDLEEVFGYLDRNALFA
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHCCCCEEE
GQWQMRKSKDQSREEYEQQLRDKAEPVLQEWLQRARSEKLLTPRVAYGYFPCGRDGNAVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEE
VFDPNDTTRELGRFELPRQRSGNTYCIADFYRDLSSNGEPTDMLPMQAVTMGEKASAFAK
EECCCCCHHHHHCCCCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHH
ELFQADRYSDYLYFHGLGVQMAEALAEWTHARIRAELGFAADEPEALRDVLAQRYRGSRY
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
SFGYPACPNVADSRPQLDWLEADRIGLSMDDSDQLEPEQSTTALVALHSQARYFSA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCEEEEEEHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]