Click here to switch to the map view.

The map label for this gene is gmpB [H]

Identifier: 148241966

GI number: 148241966

Start: 788160

End: 789701

Strand: Direct

Name: gmpB [H]

Synonym: SynRCC307_0867

Alternate gene names: 148241966

Gene position: 788160-789701 (Clockwise)

Preceding gene: 148241961

Following gene: 148241967

Centisome position: 35.42

GC content: 62.78

Gene sequence:

>1542_bases
TTGCCCACGGAGGGGCGCTCGACGCTTTGCGCCAACGACACACCCCAGATCAAGGCGGCGATCGCAAAGCTCAGCAAAGC
CAGCAAGGTCAGCCATGGGGTCGATCGCCTGGTTGGTTCCTTGCTTGGCACCGGGGCTCAGTCACTGCAAGGCATTGTCA
CCGGTGAGCGCAAGGTTGGTGCGTACGATGCGCCCCGAACTGAGTCAGGGCCCTTGGCGACGCGGATCTTGCTGGTGCGG
CACGGCCTCAGCAGCTTCAACTTGGAGGGCCGGATTCAAGGCCGGGAAGATGCCTCCAAGTTGAGCGATCCAGGCATGGA
GCAGGCCCGTCAGGTGGGCCGTGCCCTGCGCGATATTCCTCTCACCGCGGCATTTTGTTCGCCATTGCAGCGCGCCCAGT
TCACTGCTGAGCTCGCCCTGCAGGAGCAAGGCCAAGGCCTCAAGGCCACCAGCACCGATCAGTTGCTGGAGATCGACCTC
ACCCCTTGGAGTGGTTTGGCCCGTGGAGAGGTGGCCCAAAAAGATCCGCAGCAGGAATTGAACTGGCGCCAAGCACCTGC
CGAATTGCAACTGCAGCGCGCCGATGGCAGCTCCTATTACCCGGTGCGGGAACTCCGGCAGCAGGCCGAAGCGTTTTGGC
AGGACTTGCAGCAACGCTTCCCCGCCGAGGAAGACCACAGCGTGTTGGTGGTGGCCCATAACGGCATCCTGCGTTGCCTG
TTATTGGCGGCCCTTGGCTTGCCGGCTGAGCACTTCAATCGCTACCGCATCAACAATGCCTCGCTCTCGGTGCTCAACCT
GCGTCCAGGCGGACAAGTGCAGATTGAGTCGCTGAACACCGTCTCCCATCTCGGTGAGGCCTTGCCCAAGCGCAGCTCTG
GTCCGCGTGTGCTGCTGGTGCGCCACGGCGAAACCAATTGGAACCGGCAAGGGCGCTTTCAAGGCCAGATCGATATCCCC
CTCAATGAGCAGGGCCACGCCCAGGCCCATGCGGCCGGTGAGTTCCTGAAGACGGTGGCTCTCGATCGCGCCTACACCAG
CTCCATGTCGCGTCCGCGTCAGACCGCTGAGGCGATTTTGAAATTGCAGGGTGCTTCAGTACCGATGACCAGCTGCCCGG
GTCTGGTGGAGATCGGCCATGGCGCTTGGGAAGGATGCCTGGAGGAGGAAATTCGCGCCGGCTGGCCTGATCTGTTAGCC
GCCTGGCAGAGCCTTCCCCACACCGTGGAAATGCCCGGCGAGGGAGGCGAAACGATTCAGCAGGTGTGGGATCGCTCGGT
GCAGGCCTTTGCGCGAATCGTTGCTGGCCTCGGCGATGGAGAAACGGCGCTGGTGGTGGCCCACGATGCGGTGAATAAAA
CGATCCTTTGCCATCTGCTCGGTCTTGGCCCCGCCGACATCTGGGCGGTCAAGCAGGGCAACGGTGGGGTCAGCGTGATC
GATTACGGCGCTGGGGCTCAAGGAGATGCCGTAGTGGCCAGCCTCAACCTCACCAGCCATCTTGGAGGCGTGTTGGATCG
CACGGCGGCCGGGGCTCTTTGA

Upstream 100 bases:

>100_bases
TTGTTGCAGGGCTTGCAGCAATTTTGCTTCGGCCGCTTTGGATGAATCGCCTTGTCGGCTGGCGAGCACTTCCAGCTCCA
GCTGACGTTGCTCCAGGGCA

Downstream 100 bases:

>100_bases
AACGTCTTCTGCGGGGAGTGCAGCTGCTGGAGGGGCCAGGCGTTCCCTTGCAGCGCACCTCTGCTCTGTTGGAAGGCCAA
TCGCTCCTGGCTTGGGGTGA

Product: phosphoglycerate mutase

Products: 3-phospho-D-glycerate

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MPTEGRSTLCANDTPQIKAAIAKLSKASKVSHGVDRLVGSLLGTGAQSLQGIVTGERKVGAYDAPRTESGPLATRILLVR
HGLSSFNLEGRIQGREDASKLSDPGMEQARQVGRALRDIPLTAAFCSPLQRAQFTAELALQEQGQGLKATSTDQLLEIDL
TPWSGLARGEVAQKDPQQELNWRQAPAELQLQRADGSSYYPVRELRQQAEAFWQDLQQRFPAEEDHSVLVVAHNGILRCL
LLAALGLPAEHFNRYRINNASLSVLNLRPGGQVQIESLNTVSHLGEALPKRSSGPRVLLVRHGETNWNRQGRFQGQIDIP
LNEQGHAQAHAAGEFLKTVALDRAYTSSMSRPRQTAEAILKLQGASVPMTSCPGLVEIGHGAWEGCLEEEIRAGWPDLLA
AWQSLPHTVEMPGEGGETIQQVWDRSVQAFARIVAGLGDGETALVVAHDAVNKTILCHLLGLGPADIWAVKQGNGGVSVI
DYGAGAQGDAVVASLNLTSHLGGVLDRTAAGAL

Sequences:

>Translated_513_residues
MPTEGRSTLCANDTPQIKAAIAKLSKASKVSHGVDRLVGSLLGTGAQSLQGIVTGERKVGAYDAPRTESGPLATRILLVR
HGLSSFNLEGRIQGREDASKLSDPGMEQARQVGRALRDIPLTAAFCSPLQRAQFTAELALQEQGQGLKATSTDQLLEIDL
TPWSGLARGEVAQKDPQQELNWRQAPAELQLQRADGSSYYPVRELRQQAEAFWQDLQQRFPAEEDHSVLVVAHNGILRCL
LLAALGLPAEHFNRYRINNASLSVLNLRPGGQVQIESLNTVSHLGEALPKRSSGPRVLLVRHGETNWNRQGRFQGQIDIP
LNEQGHAQAHAAGEFLKTVALDRAYTSSMSRPRQTAEAILKLQGASVPMTSCPGLVEIGHGAWEGCLEEEIRAGWPDLLA
AWQSLPHTVEMPGEGGETIQQVWDRSVQAFARIVAGLGDGETALVVAHDAVNKTILCHLLGLGPADIWAVKQGNGGVSVI
DYGAGAQGDAVVASLNLTSHLGGVLDRTAAGAL
>Mature_512_residues
PTEGRSTLCANDTPQIKAAIAKLSKASKVSHGVDRLVGSLLGTGAQSLQGIVTGERKVGAYDAPRTESGPLATRILLVRH
GLSSFNLEGRIQGREDASKLSDPGMEQARQVGRALRDIPLTAAFCSPLQRAQFTAELALQEQGQGLKATSTDQLLEIDLT
PWSGLARGEVAQKDPQQELNWRQAPAELQLQRADGSSYYPVRELRQQAEAFWQDLQQRFPAEEDHSVLVVAHNGILRCLL
LAALGLPAEHFNRYRINNASLSVLNLRPGGQVQIESLNTVSHLGEALPKRSSGPRVLLVRHGETNWNRQGRFQGQIDIPL
NEQGHAQAHAAGEFLKTVALDRAYTSSMSRPRQTAEAILKLQGASVPMTSCPGLVEIGHGAWEGCLEEEIRAGWPDLLAA
WQSLPHTVEMPGEGGETIQQVWDRSVQAFARIVAGLGDGETALVVAHDAVNKTILCHLLGLGPADIWAVKQGNGGVSVID
YGAGAQGDAVVASLNLTSHLGGVLDRTAAGAL

Specific function: Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activtiy [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=187, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790856, Length=193, Percent_Identity=33.160621761658, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786970, Length=94, Percent_Identity=39.3617021276596, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322896, Length=193, Percent_Identity=30.0518134715026, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 5.4.2.1

Molecular weight: Translated: 54997; Mature: 54866

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTEGRSTLCANDTPQIKAAIAKLSKASKVSHGVDRLVGSLLGTGAQSLQGIVTGERKVG
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
AYDAPRTESGPLATRILLVRHGLSSFNLEGRIQGREDASKLSDPGMEQARQVGRALRDIP
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHCC
LTAAFCSPLQRAQFTAELALQEQGQGLKATSTDQLLEIDLTPWSGLARGEVAQKDPQQEL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCCHHHC
NWRQAPAELQLQRADGSSYYPVRELRQQAEAFWQDLQQRFPAEEDHSVLVVAHNGILRCL
CHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHH
LLAALGLPAEHFNRYRINNASLSVLNLRPGGQVQIESLNTVSHLGEALPKRSSGPRVLLV
HHHHHCCCHHHHCCEEECCCCEEEEEECCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEE
RHGETNWNRQGRFQGQIDIPLNEQGHAQAHAAGEFLKTVALDRAYTSSMSRPRQTAEAIL
ECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KLQGASVPMTSCPGLVEIGHGAWEGCLEEEIRAGWPDLLAAWQSLPHTVEMPGEGGETIQ
HHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCHHHH
QVWDRSVQAFARIVAGLGDGETALVVAHDAVNKTILCHLLGLGPADIWAVKQGNGGVSVI
HHHHHHHHHHHHHHHCCCCCCEEEEEEECHHCHHHHHHHHCCCCCCEEEEEECCCCEEEE
DYGAGAQGDAVVASLNLTSHLGGVLDRTAAGAL
ECCCCCCCCEEEEEECHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PTEGRSTLCANDTPQIKAAIAKLSKASKVSHGVDRLVGSLLGTGAQSLQGIVTGERKVG
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
AYDAPRTESGPLATRILLVRHGLSSFNLEGRIQGREDASKLSDPGMEQARQVGRALRDIP
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHCC
LTAAFCSPLQRAQFTAELALQEQGQGLKATSTDQLLEIDLTPWSGLARGEVAQKDPQQEL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCCHHHC
NWRQAPAELQLQRADGSSYYPVRELRQQAEAFWQDLQQRFPAEEDHSVLVVAHNGILRCL
CHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHH
LLAALGLPAEHFNRYRINNASLSVLNLRPGGQVQIESLNTVSHLGEALPKRSSGPRVLLV
HHHHHCCCHHHHCCEEECCCCEEEEEECCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEE
RHGETNWNRQGRFQGQIDIPLNEQGHAQAHAAGEFLKTVALDRAYTSSMSRPRQTAEAIL
ECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KLQGASVPMTSCPGLVEIGHGAWEGCLEEEIRAGWPDLLAAWQSLPHTVEMPGEGGETIQ
HHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCCHHHH
QVWDRSVQAFARIVAGLGDGETALVVAHDAVNKTILCHLLGLGPADIWAVKQGNGGVSVI
HHHHHHHHHHHHHHHCCCCCCEEEEEEECHHCHHHHHHHHCCCCCCEEEEEECCCCEEEE
DYGAGAQGDAVVASLNLTSHLGGVLDRTAAGAL
ECCCCCCCCEEEEEECHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-phospho-D-glycerate

Specific reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]