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The map label for this gene is metA [H]

Identifier: 148241895

GI number: 148241895

Start: 727368

End: 728273

Strand: Direct

Name: metA [H]

Synonym: SynRCC307_0796

Alternate gene names: 148241895

Gene position: 727368-728273 (Clockwise)

Preceding gene: 148241894

Following gene: 148241896

Centisome position: 32.69

GC content: 57.73

Gene sequence:

>906_bases
GTGGCGCTCATTCTGCCGAAGAACTATCACAAAGTTGCGGCGATTGAGCGCAATGGGATCTCCTGGATTGAGCCTGAATT
GGCGGAGCGGCAAGACATCAGACCGCTGCGCATCGGCATCATCAACATCATGCCTTTGGGCATGCAATATGAGTTCAATT
TGTTGCATCCCCTTGGCCTTTCGCCGCTGCAGATTGAACCCGTGTGGATTCGTCTTCAATCCCACGACTACAAGACCTGG
GATCACGACCATCTCGATCAGCAATATCGCTCTTGGGAGCAAGCCAATGCATCAGCGTCCCTCGATGGTTTGATCATCAC
TGGTGCCCCTGTTGAGCATTTGGCCTACGAGCAGGTCACCTATTGGCAGGAAATGGTCGAGTTGGTTGGCATTGCCCGCA
CCCAGTGCGCCAGCACGCTGGGTCTGTGTTGGGCTGGATTTGCCTTGGCCTACCTGGCCGGGGTCGATAAGACGGCGTTT
GCGCAGAAGTTGTTTGGGGTGTTCCCCATGCGCAGCCTCAAGCCAGGGCATGCCCTGATGGGCACCCAAGACGACAGCTT
TTTCTGTCCGCAAAGCCGGCACGCTGGTTTGGATGATGCCGCCATGGAGCAGGCCCAGCGGCAAGGGCGCTTGCGTTTAC
TCGCCCACGGTGAGCAGGTGGGCTACAGCATTTTTGAAACCCCCGATCAACGTCAACTGATGCATTTGGGTCATCCGGAG
TACAGCTCCGGGCGCTTGCTCGCGGAGATGGAACGGGACCGTGCTCGCGGTGATGTGCCGCCGCCGCAAAACTTTGATGC
CGAACTGCCGCAAACGCTGTGGCGCTCCCACCGCAATCTGTTTTTTCAGCAGTGGCTCTGGTTCTGCTATCAGCGCATCA
GCCTGGCCTCCCCCGCAGGGGCTTAA

Upstream 100 bases:

>100_bases
CATGGTGCGCGTTTCGGTGGGCATTGAGCACATTGATGACATCGTTGCCGACTTCAGCCAGGCCCTCGCGGGCCTGAGTT
GACGACGAGGGCAAGAGACC

Downstream 100 bases:

>100_bases
GGCTTGACTGGCTTGATCCTCTACAGCTTTCGGCGTTGCCCCTATGCGATTCGGGCCCGTTTGGCCCTGCGTCAAGCCGG
CATTACCCCCGAACTGCGGG

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MALILPKNYHKVAAIERNGISWIEPELAERQDIRPLRIGIINIMPLGMQYEFNLLHPLGLSPLQIEPVWIRLQSHDYKTW
DHDHLDQQYRSWEQANASASLDGLIITGAPVEHLAYEQVTYWQEMVELVGIARTQCASTLGLCWAGFALAYLAGVDKTAF
AQKLFGVFPMRSLKPGHALMGTQDDSFFCPQSRHAGLDDAAMEQAQRQGRLRLLAHGEQVGYSIFETPDQRQLMHLGHPE
YSSGRLLAEMERDRARGDVPPPQNFDAELPQTLWRSHRNLFFQQWLWFCYQRISLASPAGA

Sequences:

>Translated_301_residues
MALILPKNYHKVAAIERNGISWIEPELAERQDIRPLRIGIINIMPLGMQYEFNLLHPLGLSPLQIEPVWIRLQSHDYKTW
DHDHLDQQYRSWEQANASASLDGLIITGAPVEHLAYEQVTYWQEMVELVGIARTQCASTLGLCWAGFALAYLAGVDKTAF
AQKLFGVFPMRSLKPGHALMGTQDDSFFCPQSRHAGLDDAAMEQAQRQGRLRLLAHGEQVGYSIFETPDQRQLMHLGHPE
YSSGRLLAEMERDRARGDVPPPQNFDAELPQTLWRSHRNLFFQQWLWFCYQRISLASPAGA
>Mature_300_residues
ALILPKNYHKVAAIERNGISWIEPELAERQDIRPLRIGIINIMPLGMQYEFNLLHPLGLSPLQIEPVWIRLQSHDYKTWD
HDHLDQQYRSWEQANASASLDGLIITGAPVEHLAYEQVTYWQEMVELVGIARTQCASTLGLCWAGFALAYLAGVDKTAFA
QKLFGVFPMRSLKPGHALMGTQDDSFFCPQSRHAGLDDAAMEQAQRQGRLRLLAHGEQVGYSIFETPDQRQLMHLGHPEY
SSGRLLAEMERDRARGDVPPPQNFDAELPQTLWRSHRNLFFQQWLWFCYQRISLASPAGA

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=299, Percent_Identity=32.7759197324415, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 34335; Mature: 34203

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALILPKNYHKVAAIERNGISWIEPELAERQDIRPLRIGIINIMPLGMQYEFNLLHPLGL
CEEECCCCCCEEEEEECCCCCCCCCHHHHHCCCCCEEEEEEEEEECCCEEEEEEECCCCC
SPLQIEPVWIRLQSHDYKTWDHDHLDQQYRSWEQANASASLDGLIITGAPVEHLAYEQVT
CCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHH
YWQEMVELVGIARTQCASTLGLCWAGFALAYLAGVDKTAFAQKLFGVFPMRSLKPGHALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEE
GTQDDSFFCPQSRHAGLDDAAMEQAQRQGRLRLLAHGEQVGYSIFETPDQRQLMHLGHPE
CCCCCCEECCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHCCHHHCCCCHHHHHHCCCCC
YSSGRLLAEMERDRARGDVPPPQNFDAELPQTLWRSHRNLFFQQWLWFCYQRISLASPAG
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
A
C
>Mature Secondary Structure 
ALILPKNYHKVAAIERNGISWIEPELAERQDIRPLRIGIINIMPLGMQYEFNLLHPLGL
EEECCCCCCEEEEEECCCCCCCCCHHHHHCCCCCEEEEEEEEEECCCEEEEEEECCCCC
SPLQIEPVWIRLQSHDYKTWDHDHLDQQYRSWEQANASASLDGLIITGAPVEHLAYEQVT
CCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHH
YWQEMVELVGIARTQCASTLGLCWAGFALAYLAGVDKTAFAQKLFGVFPMRSLKPGHALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEE
GTQDDSFFCPQSRHAGLDDAAMEQAQRQGRLRLLAHGEQVGYSIFETPDQRQLMHLGHPE
CCCCCCEECCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHCCHHHCCCCHHHHHHCCCCC
YSSGRLLAEMERDRARGDVPPPQNFDAELPQTLWRSHRNLFFQQWLWFCYQRISLASPAG
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]