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The map label for this gene is uppS [H]

Identifier: 148241891

GI number: 148241891

Start: 723325

End: 724104

Strand: Direct

Name: uppS [H]

Synonym: SynRCC307_0792

Alternate gene names: 148241891

Gene position: 723325-724104 (Clockwise)

Preceding gene: 148241890

Following gene: 148241892

Centisome position: 32.51

GC content: 62.69

Gene sequence:

>780_bases
ATGAGCCGGCTTCCGGTGGCGGCCGCTAGGCCTGCCCCCACCACTGCCTTGCCTGCTGTCTTGCAGGCAGACCAGCTGCC
CGTCCATGTGGCCGTGATCATGGATGGCAATGGCCGCTGGGCGCGTCAGCGGGGCTTGCCCAGGGTGATGGGCCATCGCC
AGGGGGTGGAAGCCCTCAAGCGCACCTTGCGTTTATGCAGTGACTGGGGCATTGGGGCGTTGACGGCCTATGCCTTCTCG
ACGGAGAACTGGTCCCGTCCTGGCGAAGAGGTCAGCTTTTTGATGACCCTGTTTGAGCAGGTGTTGGCCCGTGAGCTCGA
GGCCCTCCAGAAAGAGCAGGTGCGCATTCGCTTCCTCGGCGATCTGGCTCCCTTGCCCGCCAAGCTTCAGGCCCTCATCA
CCGAAGCCACTGAGCGTTCAGCAGCCAACAGCGGCATTCATTTCAATGTATGCACCAACTACGGCAGCCGCCAGGAGCTG
GTGCACGCGGCCCGCGCCTTGGCAGCTCAGGTGCAGCGCGGTGAGTTGGACCCCGACGCCATCGATGAGCGTGCCTTTGC
GGCCCAGTTGCATACGGCCGGACAACCGGATCCTGATTTATTGATTCGCACCAGCGGTGAGCAGCGGCTGAGCAATTTCC
TGCTCTGGCAGCTGGCCTACGCCGAACTGCATGTCACCGATGTGTTGTGGCCTGATTTTGATGCGACGGCCCTGACGCAG
GCCCTGGTTGATTTCCAGGGCCGTCAGCGCCGTTTTGGTGGCGTGCAAGAGGAGATCTGA

Upstream 100 bases:

>100_bases
GCGAGTTGCTGAGTGAGGCGGTGAGCCGGCGTCAGGCGCGTACGCTGCCTAAATCCTCTTTGAGTGGAGATCGTTCCGAC
TCCACCACGCGAGTGCGTTC

Downstream 100 bases:

>100_bases
TGTCCGCTCTGATTCGCCACGACTGGGATCTCGCTGAAATCGAAGCCTTGCTGGAGCTGCCGTTGGTGGATCTGCTTTGG
CACGCTCAGCAGGTGCATCG

Product: undecaprenyl pyrophosphate synthase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSRLPVAAARPAPTTALPAVLQADQLPVHVAVIMDGNGRWARQRGLPRVMGHRQGVEALKRTLRLCSDWGIGALTAYAFS
TENWSRPGEEVSFLMTLFEQVLARELEALQKEQVRIRFLGDLAPLPAKLQALITEATERSAANSGIHFNVCTNYGSRQEL
VHAARALAAQVQRGELDPDAIDERAFAAQLHTAGQPDPDLLIRTSGEQRLSNFLLWQLAYAELHVTDVLWPDFDATALTQ
ALVDFQGRQRRFGGVQEEI

Sequences:

>Translated_259_residues
MSRLPVAAARPAPTTALPAVLQADQLPVHVAVIMDGNGRWARQRGLPRVMGHRQGVEALKRTLRLCSDWGIGALTAYAFS
TENWSRPGEEVSFLMTLFEQVLARELEALQKEQVRIRFLGDLAPLPAKLQALITEATERSAANSGIHFNVCTNYGSRQEL
VHAARALAAQVQRGELDPDAIDERAFAAQLHTAGQPDPDLLIRTSGEQRLSNFLLWQLAYAELHVTDVLWPDFDATALTQ
ALVDFQGRQRRFGGVQEEI
>Mature_258_residues
SRLPVAAARPAPTTALPAVLQADQLPVHVAVIMDGNGRWARQRGLPRVMGHRQGVEALKRTLRLCSDWGIGALTAYAFST
ENWSRPGEEVSFLMTLFEQVLARELEALQKEQVRIRFLGDLAPLPAKLQALITEATERSAANSGIHFNVCTNYGSRQELV
HAARALAAQVQRGELDPDAIDERAFAAQLHTAGQPDPDLLIRTSGEQRLSNFLLWQLAYAELHVTDVLWPDFDATALTQA
LVDFQGRQRRFGGVQEEI

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580742, Length=230, Percent_Identity=44.7826086956522, Blast_Score=187, Evalue=7e-48,
Organism=Homo sapiens, GI45580738, Length=230, Percent_Identity=44.7826086956522, Blast_Score=187, Evalue=8e-48,
Organism=Escherichia coli, GI1786371, Length=238, Percent_Identity=46.6386554621849, Blast_Score=231, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI71993029, Length=226, Percent_Identity=39.3805309734513, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319474, Length=230, Percent_Identity=37.8260869565217, Blast_Score=142, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6323748, Length=230, Percent_Identity=33.9130434782609, Blast_Score=122, Evalue=4e-29,
Organism=Drosophila melanogaster, GI18857969, Length=209, Percent_Identity=39.7129186602871, Blast_Score=154, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 28654; Mature: 28523

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLPVAAARPAPTTALPAVLQADQLPVHVAVIMDGNGRWARQRGLPRVMGHRQGVEALK
CCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHH
RTLRLCSDWGIGALTAYAFSTENWSRPGEEVSFLMTLFEQVLARELEALQKEQVRIRFLG
HHHHHHHCCCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DLAPLPAKLQALITEATERSAANSGIHFNVCTNYGSRQELVHAARALAAQVQRGELDPDA
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHH
IDERAFAAQLHTAGQPDPDLLIRTSGEQRLSNFLLWQLAYAELHVTDVLWPDFDATALTQ
HHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ALVDFQGRQRRFGGVQEEI
HHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure 
SRLPVAAARPAPTTALPAVLQADQLPVHVAVIMDGNGRWARQRGLPRVMGHRQGVEALK
CCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHH
RTLRLCSDWGIGALTAYAFSTENWSRPGEEVSFLMTLFEQVLARELEALQKEQVRIRFLG
HHHHHHHCCCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DLAPLPAKLQALITEATERSAANSGIHFNVCTNYGSRQELVHAARALAAQVQRGELDPDA
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHH
IDERAFAAQLHTAGQPDPDLLIRTSGEQRLSNFLLWQLAYAELHVTDVLWPDFDATALTQ
HHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ALVDFQGRQRRFGGVQEEI
HHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]