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The map label for this gene is trpC

Identifier: 148241715

GI number: 148241715

Start: 550132

End: 551016

Strand: Direct

Name: trpC

Synonym: SynRCC307_0616

Alternate gene names: 148241715

Gene position: 550132-551016 (Clockwise)

Preceding gene: 148241714

Following gene: 148241721

Centisome position: 24.73

GC content: 60.68

Gene sequence:

>885_bases
ATGGAAATCCGTCGCCGGCCGCCCAACCCCAAGGTGCGTGTGGCCCATCTGGAATACGCCGTCCCCCACGACGATGAGGC
CCCGCGCCACATCCTTGAGGAGATCGTTTGGGAGAAAGACCGCGAAGTCGCCCAGGCCCGTGAGCGGGTGCCACTGGAGA
AGCTGAAATCCCAGGTGGCGGCCTTGCCGGCGCCCCGTGATTTCGTCGCTGCGTTGAAGGCCAGCTGCCGTAAGCCGGCA
GTGATTGCTGAGGTGAAAAAGGCTAGCCCCAGCAAAGGGGTAATCCGCGAAGACTTTGACCCCGAGGCCATCGCCAAGGC
CTATGCCGAAGGTGGAGCCAGCTGCTTGTCGGTGCTCACCGACAAGCGCTTTTTCCAAGGTGGTTTTGAGGTGCTGGTGC
AGGTGCGCCAGGTGGTGGATTTGCCCCTGCTCTGCAAGGAGTTCATCCTCAGCCCCTATCAGCTGTATCAGGCCCGCGCC
GCTGGCGCTGATGCGGTGCTGTTGATTGCAGCGATCCTCACCGATCAAGACATCAGCTATCTGCTCAAAGTGGCCCGCAG
CCTTGGTTTGCAGGTGCTGCTGGAAGTGCATGACGCCGCTGAGCTGGAGCGTGCGCTCGGCTTTGAGGGCGTGCAGCTGA
TCGGCATCAACAACCGCGATCTCACCAGTTTTGACACCGATTTGGCGACAACAGAAACGCTGACGGCTACCTACGGCGAG
CAGTTACGTCAAAGCGGCGCGCTGCTGGTGAGTGAATCGGGTTTGTTCAGTCGTGATGATCTCGATCGGGTGCAGAGCGC
TGGGGCCGATGCGGTGCTGGTGGGTGAGGCCTTAATGCGCCAAAGCGATGTACAGCAGGCCCTGGAAACGTTGATTAGCG
GTTGA

Upstream 100 bases:

>100_bases
GTGACCTCGTTTATGAGGTGCATACCCATCCCACCTTGAGTGAGGTGGTGGAATCGGCCTACAAGCAGGCCGCCCATGCC
CTTGCTGCTTGAGCTCCGCC

Downstream 100 bases:

>100_bases
TTTCTGCTGCGTGACGTTGATTAGGGGATAGGGAGTACCGCAACAATTGTTCTGAATCGGTTGAATGGAAAAAGGCTCAG
AGTCTCTGCAAATTATTTCT

Product: indole-3-glycerol-phosphate synthase

Products: NA

Alternate protein names: IGPS

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MEIRRRPPNPKVRVAHLEYAVPHDDEAPRHILEEIVWEKDREVAQARERVPLEKLKSQVAALPAPRDFVAALKASCRKPA
VIAEVKKASPSKGVIREDFDPEAIAKAYAEGGASCLSVLTDKRFFQGGFEVLVQVRQVVDLPLLCKEFILSPYQLYQARA
AGADAVLLIAAILTDQDISYLLKVARSLGLQVLLEVHDAAELERALGFEGVQLIGINNRDLTSFDTDLATTETLTATYGE
QLRQSGALLVSESGLFSRDDLDRVQSAGADAVLVGEALMRQSDVQQALETLISG

Sequences:

>Translated_294_residues
MEIRRRPPNPKVRVAHLEYAVPHDDEAPRHILEEIVWEKDREVAQARERVPLEKLKSQVAALPAPRDFVAALKASCRKPA
VIAEVKKASPSKGVIREDFDPEAIAKAYAEGGASCLSVLTDKRFFQGGFEVLVQVRQVVDLPLLCKEFILSPYQLYQARA
AGADAVLLIAAILTDQDISYLLKVARSLGLQVLLEVHDAAELERALGFEGVQLIGINNRDLTSFDTDLATTETLTATYGE
QLRQSGALLVSESGLFSRDDLDRVQSAGADAVLVGEALMRQSDVQQALETLISG
>Mature_294_residues
MEIRRRPPNPKVRVAHLEYAVPHDDEAPRHILEEIVWEKDREVAQARERVPLEKLKSQVAALPAPRDFVAALKASCRKPA
VIAEVKKASPSKGVIREDFDPEAIAKAYAEGGASCLSVLTDKRFFQGGFEVLVQVRQVVDLPLLCKEFILSPYQLYQARA
AGADAVLLIAAILTDQDISYLLKVARSLGLQVLLEVHDAAELERALGFEGVQLIGINNRDLTSFDTDLATTETLTATYGE
QLRQSGALLVSESGLFSRDDLDRVQSAGADAVLVGEALMRQSDVQQALETLISG

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family

Homologues:

Organism=Escherichia coli, GI87081863, Length=264, Percent_Identity=40.9090909090909, Blast_Score=171, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6322638, Length=237, Percent_Identity=40.9282700421941, Blast_Score=166, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPC_SYNR3 (A5GRL0)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001226872.1
- ProteinModelPortal:   A5GRL0
- SMR:   A5GRL0
- STRING:   A5GRL0
- GeneID:   5158818
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_0616
- eggNOG:   COG0134
- HOGENOM:   HBG540956
- OMA:   VDLPLLC
- ProtClustDB:   PRK00278
- HAMAP:   MF_00134_B
- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00218 IGPS; SSF51366 RibP_bind_barrel

EC number: =4.1.1.48

Molecular weight: Translated: 32183; Mature: 32183

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00614 IGPS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRRRPPNPKVRVAHLEYAVPHDDEAPRHILEEIVWEKDREVAQARERVPLEKLKSQVA
CCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
ALPAPRDFVAALKASCRKPAVIAEVKKASPSKGVIREDFDPEAIAKAYAEGGASCLSVLT
CCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHH
DKRFFQGGFEVLVQVRQVVDLPLLCKEFILSPYQLYQARAAGADAVLLIAAILTDQDISY
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHH
LLKVARSLGLQVLLEVHDAAELERALGFEGVQLIGINNRDLTSFDTDLATTETLTATYGE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
QLRQSGALLVSESGLFSRDDLDRVQSAGADAVLVGEALMRQSDVQQALETLISG
HHHHCCCEEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIRRRPPNPKVRVAHLEYAVPHDDEAPRHILEEIVWEKDREVAQARERVPLEKLKSQVA
CCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
ALPAPRDFVAALKASCRKPAVIAEVKKASPSKGVIREDFDPEAIAKAYAEGGASCLSVLT
CCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHH
DKRFFQGGFEVLVQVRQVVDLPLLCKEFILSPYQLYQARAAGADAVLLIAAILTDQDISY
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHH
LLKVARSLGLQVLLEVHDAAELERALGFEGVQLIGINNRDLTSFDTDLATTETLTATYGE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
QLRQSGALLVSESGLFSRDDLDRVQSAGADAVLVGEALMRQSDVQQALETLISG
HHHHCCCEEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA