Click here to switch to the map view.

The map label for this gene is ubiE [H]

Identifier: 148241680

GI number: 148241680

Start: 514751

End: 515443

Strand: Direct

Name: ubiE [H]

Synonym: SynRCC307_0581

Alternate gene names: 148241680

Gene position: 514751-515443 (Clockwise)

Preceding gene: 148241679

Following gene: 148241682

Centisome position: 23.14

GC content: 66.52

Gene sequence:

>693_bases
ATGCCGGCTGAAGCCCAGGCAGTACGCCAGCTCTTTGATGAGGTGGCTCCCCACTACGACCGCCTCAACGACCTGTTGAG
CCTCGGCCTGCACAGGCTGTGGAAGCGCGAAATGGTGCAGCGCTTGGCTCCCGTTGCCGGCGAGCAGTGGCTCGATCTCT
GCTGCGGCACTGGCGACTTGGCCCTCGTGCTGGCCGAGCGTTTGCGCCGCGGGGGGGCTGTGTTGGCTGTGGATGCAGCA
GCGGCTCCATTGCTGCAGGCCCGCCGCCGCCACAAGCGTTGCCCTTGGCTGCCGGTGGAGTGGCTCCAGGCTGATGCCCT
GGCGGTGCCTCGGGCGGCTGCAAGTTTTGACGGGGCGGTGATGGCCTATGGCCTGCGCAACCTCCCGGATCCAGCGGCGG
GTTTGCGGGAACTCAGGCGCTTGTTGCAACGCGATGGCCGCGCGGCGGTCTTGGATTTCAATCGCGGCGGCGGGGCAGCC
TCAGCGCTGCAGACCCAGGCCTTACGCCGGGTGGTGGTGCCGGTGGCGAGCCAGCTGGGGCTCAAGGAGCAATACGCCTA
TTTGGAGACGAGCATTGCTGAGTTCCCCACCGGCTTTGAGCAAGAGCAGATGGCCCTCTCAGCAGGCTTTAGCTGGGCGC
AGCATCGCCCGATTGCCGGGGGCTTGATGGGCTTGTTGGAACTGCGCTGCTGA

Upstream 100 bases:

>100_bases
ATGCTGGCCGGCTGTTTGGTGTGTTCGGCTGCCGTGGGGCTCTCTACCGTGATGGTGATCAGCCTGACGGGTCCCAACGC
GCCGTTGGTTCATATCTTTC

Downstream 100 bases:

>100_bases
GCTCTACCAGTTGAAGCTCACTTGCAGGCCCGGCACGACCAATGTCTCGTTGTCGCCGGTGCCCTCGGGATTGACGATCA
CTTGAACGCCGGGTTGCAGC

Product: menaquinone biosynthesis methyltransferase UbiE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MPAEAQAVRQLFDEVAPHYDRLNDLLSLGLHRLWKREMVQRLAPVAGEQWLDLCCGTGDLALVLAERLRRGGAVLAVDAA
AAPLLQARRRHKRCPWLPVEWLQADALAVPRAAASFDGAVMAYGLRNLPDPAAGLRELRRLLQRDGRAAVLDFNRGGGAA
SALQTQALRRVVVPVASQLGLKEQYAYLETSIAEFPTGFEQEQMALSAGFSWAQHRPIAGGLMGLLELRC

Sequences:

>Translated_230_residues
MPAEAQAVRQLFDEVAPHYDRLNDLLSLGLHRLWKREMVQRLAPVAGEQWLDLCCGTGDLALVLAERLRRGGAVLAVDAA
AAPLLQARRRHKRCPWLPVEWLQADALAVPRAAASFDGAVMAYGLRNLPDPAAGLRELRRLLQRDGRAAVLDFNRGGGAA
SALQTQALRRVVVPVASQLGLKEQYAYLETSIAEFPTGFEQEQMALSAGFSWAQHRPIAGGLMGLLELRC
>Mature_229_residues
PAEAQAVRQLFDEVAPHYDRLNDLLSLGLHRLWKREMVQRLAPVAGEQWLDLCCGTGDLALVLAERLRRGGAVLAVDAAA
APLLQARRRHKRCPWLPVEWLQADALAVPRAAASFDGAVMAYGLRNLPDPAAGLRELRRLLQRDGRAAVLDFNRGGGAAS
ALQTQALRRVVVPVASQLGLKEQYAYLETSIAEFPTGFEQEQMALSAGFSWAQHRPIAGGLMGLLELRC

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=228, Percent_Identity=32.0175438596491, Blast_Score=110, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17557039, Length=229, Percent_Identity=30.5676855895196, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24641702, Length=238, Percent_Identity=31.5126050420168, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 25180; Mature: 25049

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS01183 UBIE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAEAQAVRQLFDEVAPHYDRLNDLLSLGLHRLWKREMVQRLAPVAGEQWLDLCCGTGDL
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHH
ALVLAERLRRGGAVLAVDAAAAPLLQARRRHKRCPWLPVEWLQADALAVPRAAASFDGAV
HHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCHH
MAYGLRNLPDPAAGLRELRRLLQRDGRAAVLDFNRGGGAASALQTQALRRVVVPVASQLG
HHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
LKEQYAYLETSIAEFPTGFEQEQMALSAGFSWAQHRPIAGGLMGLLELRC
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PAEAQAVRQLFDEVAPHYDRLNDLLSLGLHRLWKREMVQRLAPVAGEQWLDLCCGTGDL
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHH
ALVLAERLRRGGAVLAVDAAAAPLLQARRRHKRCPWLPVEWLQADALAVPRAAASFDGAV
HHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCHH
MAYGLRNLPDPAAGLRELRRLLQRDGRAAVLDFNRGGGAASALQTQALRRVVVPVASQLG
HHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
LKEQYAYLETSIAEFPTGFEQEQMALSAGFSWAQHRPIAGGLMGLLELRC
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA