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The map label for this gene is recQ [H]

Identifier: 148241552

GI number: 148241552

Start: 425605

End: 427197

Strand: Direct

Name: recQ [H]

Synonym: SynRCC307_0453

Alternate gene names: 148241552

Gene position: 425605-427197 (Clockwise)

Preceding gene: 148241551

Following gene: 148241555

Centisome position: 19.13

GC content: 65.41

Gene sequence:

>1593_bases
GTGAAGGAATCCAGTGCATCTCTGCTGCAGTCGCTGCAGCAGCACTTCGGTTACAGCGACTTTCGTCCCGGTCAGCGCGA
GGTGGTTGAGGCCCTGCTTGAGGGCCGTGATTGCTTGGCTGTTTTGCCGACGGGGGCGGGGAAGTCGCTTTGTTATCAAC
TGCCGGCCCTGGTGCGCGGTGGGGTGGTGCTTGTGATTTCTCCACTGGTCGCCTTGATGCAAGACCAGGTGGCTCAGCTG
CGCCGCCGCGGCATCGCCGCGGCTTGTTTGCATAACGGGTTGCCGTTGCAGGAGCTGCGCAAGCTGCAGCAGCAGATTCA
GCAAGGCACGCTGCGGCTGTTGTATCTCGCCCCTGAGCGCCTGCAGGGTGAGGCTTGCCGCCAGTTGCTGGAGGATCTGC
ATGATCAACGCCAGCTCGTGGCATTGGCGGTGGATGAAGCCCACTGCATCAGCAATTGGGGCCACGACTTTCGGCCTGAT
TACCGTCGCTTGGGCCAACTGCGCCGGCTGTGCCCTGGCGTTCCCCTGGTCGCGCTGAGTGCCACGGCCCCACCGCGGGT
GCGGGCCGACATCATTCGCTTGCTCAGCTTGCGGCGACCGTTGATCCAGGTGCGCTCAGCCCAGAGGCCCAACCTGCGCT
ACCGCATGCTTTGGCGCCCGGAGGATCCCTTGGAGCTGGTGCTGGCGGAAGCCCGCAGCGCCCGCGGTGCCGTGCTGATC
TACAGCCGCACTCGCCGAGGTGTGGAGCGTTGGGCGGCCAAGTTGCGTCAGGCCGGATTGCCGGCCTTGGCGTATCACGC
CGGCATGGATGCTGAGAGTCGCCTGTTGGCGCTGCAGCAATTTCAAGAGGAGCCCCAGCCGGTGCTGGTGGCCACCGTGG
CCTTTGGGATGGGGGTCGACCGCCCGGATGTGGGCTTGGTGCTGCACCTCGAACTGCCGGCCAGCCCGGAGGGCTATTTG
CAGGAATCAGGCCGTGCCGGCCGTGATGGTCAGCCCGCTGAGGTGCTGCTGCTGTATTCCGATAGCGACCGCAGCCGCTT
GGCCTGGGCTGTGCGCCAGGGCCGCGATGGCGCGGCAGCTCAGCTGCGGCGGATGGAGTCGATTGCGGAAGGTCCTGATT
GCCGCCAGCAGGCCTTGCTCTTGGCGGTTGGTGAGATGGCTGAACCTTGCGGTTGTTGCGACCGCTGCGAGGAGCCAGTG
TTGATTCAAGACGGCCAACAGTTGGCTCAGCCCCTGCTGCGCGCGCTTCAGCAAGCCGAGGAAGGCCTCGAAGCGGCTGA
TCTGGCGGCTGATTTGGCTGATCAGGCCCACCCAGCACCGCTGTGGCGCTGGGCCTTGCGGCGCCTGGTAGAGGCGGAAC
TGGTGAAGGAAGACGCCAGCGGCAAGCGCCACTGGCTCAGCAGCGCTGGAGCTGGTTGGTTGCGCCGGCCCAGGCCGCTG
CGCTGGCCTCAGCCTTTGCCGATTTTGGGATCGGCGCAGGCGGCTTTCACCAAGTCGCGCTCAAAGGCTTCAGCCGGAGA
TTCCCAGGTTTTCCAGGTGCCGCCTGAGCCGGTGATGTTGAGCTTGCGGGCGCCGCAGTTAACGGCCACATAG

Upstream 100 bases:

>100_bases
TTCAGCTGGTGGAAGAGGGGGCAGATCAGCTGGAGGCGCCACCGCTGCAGCAGGCCGCCTGAGGCCTTGCGCCCCGGGGG
GCAACCGGTACCGTCCGTGG

Downstream 100 bases:

>100_bases
AGGGGCTGTTTTTGCTTATTCAGGGTTGGGGCCACCAGGCTGCCGGCCATGGTGCGCCAGTTGTTCCAATCCACCTGCAG
TGGGCCGAAATAACGCCAGT

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MKESSASLLQSLQQHFGYSDFRPGQREVVEALLEGRDCLAVLPTGAGKSLCYQLPALVRGGVVLVISPLVALMQDQVAQL
RRRGIAAACLHNGLPLQELRKLQQQIQQGTLRLLYLAPERLQGEACRQLLEDLHDQRQLVALAVDEAHCISNWGHDFRPD
YRRLGQLRRLCPGVPLVALSATAPPRVRADIIRLLSLRRPLIQVRSAQRPNLRYRMLWRPEDPLELVLAEARSARGAVLI
YSRTRRGVERWAAKLRQAGLPALAYHAGMDAESRLLALQQFQEEPQPVLVATVAFGMGVDRPDVGLVLHLELPASPEGYL
QESGRAGRDGQPAEVLLLYSDSDRSRLAWAVRQGRDGAAAQLRRMESIAEGPDCRQQALLLAVGEMAEPCGCCDRCEEPV
LIQDGQQLAQPLLRALQQAEEGLEAADLAADLADQAHPAPLWRWALRRLVEAELVKEDASGKRHWLSSAGAGWLRRPRPL
RWPQPLPILGSAQAAFTKSRSKASAGDSQVFQVPPEPVMLSLRAPQLTAT

Sequences:

>Translated_530_residues
MKESSASLLQSLQQHFGYSDFRPGQREVVEALLEGRDCLAVLPTGAGKSLCYQLPALVRGGVVLVISPLVALMQDQVAQL
RRRGIAAACLHNGLPLQELRKLQQQIQQGTLRLLYLAPERLQGEACRQLLEDLHDQRQLVALAVDEAHCISNWGHDFRPD
YRRLGQLRRLCPGVPLVALSATAPPRVRADIIRLLSLRRPLIQVRSAQRPNLRYRMLWRPEDPLELVLAEARSARGAVLI
YSRTRRGVERWAAKLRQAGLPALAYHAGMDAESRLLALQQFQEEPQPVLVATVAFGMGVDRPDVGLVLHLELPASPEGYL
QESGRAGRDGQPAEVLLLYSDSDRSRLAWAVRQGRDGAAAQLRRMESIAEGPDCRQQALLLAVGEMAEPCGCCDRCEEPV
LIQDGQQLAQPLLRALQQAEEGLEAADLAADLADQAHPAPLWRWALRRLVEAELVKEDASGKRHWLSSAGAGWLRRPRPL
RWPQPLPILGSAQAAFTKSRSKASAGDSQVFQVPPEPVMLSLRAPQLTAT
>Mature_530_residues
MKESSASLLQSLQQHFGYSDFRPGQREVVEALLEGRDCLAVLPTGAGKSLCYQLPALVRGGVVLVISPLVALMQDQVAQL
RRRGIAAACLHNGLPLQELRKLQQQIQQGTLRLLYLAPERLQGEACRQLLEDLHDQRQLVALAVDEAHCISNWGHDFRPD
YRRLGQLRRLCPGVPLVALSATAPPRVRADIIRLLSLRRPLIQVRSAQRPNLRYRMLWRPEDPLELVLAEARSARGAVLI
YSRTRRGVERWAAKLRQAGLPALAYHAGMDAESRLLALQQFQEEPQPVLVATVAFGMGVDRPDVGLVLHLELPASPEGYL
QESGRAGRDGQPAEVLLLYSDSDRSRLAWAVRQGRDGAAAQLRRMESIAEGPDCRQQALLLAVGEMAEPCGCCDRCEEPV
LIQDGQQLAQPLLRALQQAEEGLEAADLAADLADQAHPAPLWRWALRRLVEAELVKEDASGKRHWLSSAGAGWLRRPRPL
RWPQPLPILGSAQAAFTKSRSKASAGDSQVFQVPPEPVMLSLRAPQLTAT

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=477, Percent_Identity=35.4297693920335, Blast_Score=285, Evalue=9e-77,
Organism=Homo sapiens, GI14591902, Length=426, Percent_Identity=35.2112676056338, Blast_Score=268, Evalue=1e-71,
Organism=Homo sapiens, GI14591904, Length=426, Percent_Identity=35.2112676056338, Blast_Score=268, Evalue=1e-71,
Organism=Homo sapiens, GI148612816, Length=423, Percent_Identity=37.5886524822695, Blast_Score=265, Evalue=8e-71,
Organism=Homo sapiens, GI51242943, Length=396, Percent_Identity=38.6363636363636, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI51242947, Length=396, Percent_Identity=38.6363636363636, Blast_Score=263, Evalue=4e-70,
Organism=Homo sapiens, GI110735439, Length=407, Percent_Identity=36.1179361179361, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI169218196, Length=407, Percent_Identity=36.1179361179361, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI284005309, Length=364, Percent_Identity=40.6593406593407, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI4758138, Length=342, Percent_Identity=25.1461988304094, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI148613856, Length=360, Percent_Identity=24.4444444444444, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI38201710, Length=360, Percent_Identity=24.4444444444444, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI262118318, Length=380, Percent_Identity=24.2105263157895, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI262231852, Length=380, Percent_Identity=24.2105263157895, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI216548263, Length=380, Percent_Identity=24.2105263157895, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI13518015, Length=380, Percent_Identity=24.2105263157895, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI7661920, Length=359, Percent_Identity=23.6768802228412, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI188035877, Length=354, Percent_Identity=25.4237288135593, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI41327773, Length=372, Percent_Identity=23.6559139784946, Blast_Score=76, Evalue=9e-14,
Organism=Escherichia coli, GI48994977, Length=418, Percent_Identity=46.4114832535885, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI87082221, Length=359, Percent_Identity=27.0194986072423, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71987997, Length=398, Percent_Identity=38.9447236180905, Blast_Score=272, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71987993, Length=398, Percent_Identity=38.9447236180905, Blast_Score=272, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI25145561, Length=415, Percent_Identity=35.6626506024096, Blast_Score=267, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17552866, Length=430, Percent_Identity=35.3488372093023, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI32564293, Length=411, Percent_Identity=36.4963503649635, Blast_Score=262, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17507121, Length=362, Percent_Identity=26.2430939226519, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71995724, Length=362, Percent_Identity=25.9668508287293, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17510309, Length=362, Percent_Identity=25.1381215469613, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17510307, Length=362, Percent_Identity=25.1381215469613, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995514, Length=362, Percent_Identity=25.1381215469613, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995718, Length=372, Percent_Identity=24.7311827956989, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32565321, Length=386, Percent_Identity=25.1295336787565, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17507945, Length=356, Percent_Identity=23.314606741573, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323844, Length=435, Percent_Identity=35.1724137931034, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6324217, Length=342, Percent_Identity=25.1461988304094, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320041, Length=346, Percent_Identity=23.4104046242775, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646066, Length=420, Percent_Identity=38.3333333333333, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24664226, Length=430, Percent_Identity=33.7209302325581, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI62472181, Length=430, Percent_Identity=33.7209302325581, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24664230, Length=430, Percent_Identity=33.7209302325581, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI21358123, Length=376, Percent_Identity=34.8404255319149, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28574962, Length=344, Percent_Identity=23.8372093023256, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24645031, Length=368, Percent_Identity=25, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24642151, Length=366, Percent_Identity=21.5846994535519, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644487, Length=340, Percent_Identity=22.6470588235294, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551833, Length=340, Percent_Identity=22.6470588235294, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644485, Length=340, Percent_Identity=22.6470588235294, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644483, Length=340, Percent_Identity=22.6470588235294, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644479, Length=340, Percent_Identity=22.6470588235294, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281361218, Length=340, Percent_Identity=22.6470588235294, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644481, Length=340, Percent_Identity=22.6470588235294, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17985987, Length=366, Percent_Identity=25.1366120218579, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17977678, Length=351, Percent_Identity=25.0712250712251, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666101, Length=362, Percent_Identity=24.0331491712707, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 58551; Mature: 58551

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKESSASLLQSLQQHFGYSDFRPGQREVVEALLEGRDCLAVLPTGAGKSLCYQLPALVRG
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHC
GVVLVISPLVALMQDQVAQLRRRGIAAACLHNGLPLQELRKLQQQIQQGTLRLLYLAPER
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCHH
LQGEACRQLLEDLHDQRQLVALAVDEAHCISNWGHDFRPDYRRLGQLRRLCPGVPLVALS
CCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
ATAPPRVRADIIRLLSLRRPLIQVRSAQRPNLRYRMLWRPEDPLELVLAEARSARGAVLI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEE
YSRTRRGVERWAAKLRQAGLPALAYHAGMDAESRLLALQQFQEEPQPVLVATVAFGMGVD
EHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCC
RPDVGLVLHLELPASPEGYLQESGRAGRDGQPAEVLLLYSDSDRSRLAWAVRQGRDGAAA
CCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCHHH
QLRRMESIAEGPDCRQQALLLAVGEMAEPCGCCDRCEEPVLIQDGQQLAQPLLRALQQAE
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHHH
EGLEAADLAADLADQAHPAPLWRWALRRLVEAELVKEDASGKRHWLSSAGAGWLRRPRPL
HCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
RWPQPLPILGSAQAAFTKSRSKASAGDSQVFQVPPEPVMLSLRAPQLTAT
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKESSASLLQSLQQHFGYSDFRPGQREVVEALLEGRDCLAVLPTGAGKSLCYQLPALVRG
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHC
GVVLVISPLVALMQDQVAQLRRRGIAAACLHNGLPLQELRKLQQQIQQGTLRLLYLAPER
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCHH
LQGEACRQLLEDLHDQRQLVALAVDEAHCISNWGHDFRPDYRRLGQLRRLCPGVPLVALS
CCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
ATAPPRVRADIIRLLSLRRPLIQVRSAQRPNLRYRMLWRPEDPLELVLAEARSARGAVLI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEE
YSRTRRGVERWAAKLRQAGLPALAYHAGMDAESRLLALQQFQEEPQPVLVATVAFGMGVD
EHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCC
RPDVGLVLHLELPASPEGYLQESGRAGRDGQPAEVLLLYSDSDRSRLAWAVRQGRDGAAA
CCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCHHH
QLRRMESIAEGPDCRQQALLLAVGEMAEPCGCCDRCEEPVLIQDGQQLAQPLLRALQQAE
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHHH
EGLEAADLAADLADQAHPAPLWRWALRRLVEAELVKEDASGKRHWLSSAGAGWLRRPRPL
HCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
RWPQPLPILGSAQAAFTKSRSKASAGDSQVFQVPPEPVMLSLRAPQLTAT
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]