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The map label for this gene is ywlC [H]

Identifier: 148241524

GI number: 148241524

Start: 404817

End: 405404

Strand: Direct

Name: ywlC [H]

Synonym: SynRCC307_0425

Alternate gene names: 148241524

Gene position: 404817-405404 (Clockwise)

Preceding gene: 148241523

Following gene: 148241528

Centisome position: 18.19

GC content: 68.03

Gene sequence:

>588_bases
ATGACGGCGGAAGGGTTCCAGGTGCTGGCGCAGCGGTTGCAACAGGGGGAGCCGGCCCTGTTCCCCACCGACACCTTGCC
GGCATTGGCCGCGATTCCATCTGCTGCCCAGGCGATCTGGCAGTTGAAGCAGCGACCTGCCGATAAGCCCTTGATCTTGA
TGGGGGCCTCTGTGGAGCAGCTGCTCCCTTGCTTGGGCCAAGAGCCCCCCGCTGGCTGGCAGCGCCTGGCCGAGCTGGGT
TGGCCCGGGGCACTCACGCTGGTGCTACCGGCCTGCGGGCCGGTGGTGGAGGCCCTCAACCCAGAAGGCGGGTGCAGTCT
TGGCTTGCGGGTGCCCGCCTGTGAGGCGGCCTTGCAATTGCTGCGCTGCAGTGGGCCGCTGGCCACTAGCAGTGCCAACC
GCTCCGGTGAGCCCGCTTGCCGCACGGCAGCTGAGCTGGCGCACTGCTTCCCCGAGGTGATTCGCTTGGCGCCAGAGCCT
TGGTTGCCAGGCTCTGGGCAGGCCAGCACCGTGGTGAGCTGGCAGAGCGATGGTTGGCGCGTCCTGCGTCAGGGACAGGT
GGTTGTGCCTGAGATCCTTGGCCCCTAG

Upstream 100 bases:

>100_bases
CGGTGGCTGAGCTCTTGGGCGCTGCCGGCCTGCAGGAGCGCCGTCAGGAGAGGGATCTGGAGGGGCAAATGCGTTTTGCG
GTGGTGCGCCGCTCCAACCC

Downstream 100 bases:

>100_bases
GCCAGCTCCTTGGGGATCGCTGATTAGGCCGGAAACAAATCCTCGTTGCGGTTGGCGATCGCCACCAGTGAAAGCATCAC
TGGGACCTCCACCAGCACGC

Product: translation factor

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MTAEGFQVLAQRLQQGEPALFPTDTLPALAAIPSAAQAIWQLKQRPADKPLILMGASVEQLLPCLGQEPPAGWQRLAELG
WPGALTLVLPACGPVVEALNPEGGCSLGLRVPACEAALQLLRCSGPLATSSANRSGEPACRTAAELAHCFPEVIRLAPEP
WLPGSGQASTVVSWQSDGWRVLRQGQVVVPEILGP

Sequences:

>Translated_195_residues
MTAEGFQVLAQRLQQGEPALFPTDTLPALAAIPSAAQAIWQLKQRPADKPLILMGASVEQLLPCLGQEPPAGWQRLAELG
WPGALTLVLPACGPVVEALNPEGGCSLGLRVPACEAALQLLRCSGPLATSSANRSGEPACRTAAELAHCFPEVIRLAPEP
WLPGSGQASTVVSWQSDGWRVLRQGQVVVPEILGP
>Mature_194_residues
TAEGFQVLAQRLQQGEPALFPTDTLPALAAIPSAAQAIWQLKQRPADKPLILMGASVEQLLPCLGQEPPAGWQRLAELGW
PGALTLVLPACGPVVEALNPEGGCSLGLRVPACEAALQLLRCSGPLATSSANRSGEPACRTAAELAHCFPEVIRLAPEPW
LPGSGQASTVVSWQSDGWRVLRQGQVVVPEILGP

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=135, Percent_Identity=35.5555555555556, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 20462; Mature: 20331

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEGFQVLAQRLQQGEPALFPTDTLPALAAIPSAAQAIWQLKQRPADKPLILMGASVEQ
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCHHH
LLPCLGQEPPAGWQRLAELGWPGALTLVLPACGPVVEALNPEGGCSLGLRVPACEAALQL
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHCHHHHHHHCCCCCCCEECCCCCHHHHHHHH
LRCSGPLATSSANRSGEPACRTAAELAHCFPEVIRLAPEPWLPGSGQASTVVSWQSDGWR
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHH
VLRQGQVVVPEILGP
HHHCCCEECCHHCCC
>Mature Secondary Structure 
TAEGFQVLAQRLQQGEPALFPTDTLPALAAIPSAAQAIWQLKQRPADKPLILMGASVEQ
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCHHH
LLPCLGQEPPAGWQRLAELGWPGALTLVLPACGPVVEALNPEGGCSLGLRVPACEAALQL
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHCHHHHHHHCCCCCCCEECCCCCHHHHHHHH
LRCSGPLATSSANRSGEPACRTAAELAHCFPEVIRLAPEPWLPGSGQASTVVSWQSDGWR
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHH
VLRQGQVVVPEILGP
HHHCCCEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]